In mining, particularly for phosphates, extraction is a crucial step. This phase presents several problems that must be treated to optimize ore flow. Among those constraints we find clogging of phosphate ore on different metal supports. It is therefore necessary to understand the factors behind this phenomenon to control it. We focused, in this paper, on the mechanical and thermal characterization of natural phosphate under different conditions of pressure, temperature and humidity. First, we evaluated the compressive strength of raw phosphate, to determine the threshold pressure, which lead to a compact solid phase. We also measured its different limits of friability. Secondly, we studied the structural properties of phosphate ore as a function of temperature and water content. This study was carried out using heating and water adsorption protocols. The results show that phosphate ore compacts easily when subjected to high pressures. In addition, it becomes easily friable when the mass handled is high. Furthermore, the source of phosphate, as well as external conditions, play an important role in its ability to lose moisture, which is the main reason for agglutination.