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- Research Article
- 10.1007/s00266-025-05389-4
- Jan 1, 2026
- Aesthetic plastic surgery
- Cristian Teuber Lobos + 4 more
Various surgical options exist for correcting long, hyperprojected chins, including modified genioplasty techniques, pogonion burring, soft tissue rejuvenation, and custom implants. These can be performed as standalone procedures or in conjunction with orthognathic surgery. Among these, lower chin border resection combined with meticulous soft tissue suspension offers a reliable method for enhancing mandibular contour and cervicomental definition. From 2018 to 2024, 24 patients with elongated, protrusive chins underwent genioplasty with symphysis resection and soft tissue suspension. The technique involved segmental resection of the mandibular symphysis, typically extending from the mandibular angle or first molar. Muscle insertions, including platysma and medial pterygoid, were carefully released with electrocautery. The inferior chin periosteum was sutured and repositioned. Contouring of the mandibular edge was achieved using a round bur, followed by precise hemostasis and suspension of the cervical soft tissues, including the platysma. In 14 patients, the genioglossus and digastric muscles were also anchored to the resected symphysis to enhance submental support. Mandibular reductions ranged from 5 to 10 mm. No major complications were observed. All patients expressed high satisfaction with aesthetic and functional outcomes, with a mean FACE-Q score of 96.02. This technique proved particularly valuable in cases where standard advancement or setback genioplasty alone would not sufficiently address vertical excess or soft tissue laxity. Genioplasty with symphysis resection and soft tissue suspension is a safe, reproducible technique for treating long, hyperprojected chins. The integration of soft tissue suspension is critical to optimize cervicomental angle definition and overall facial harmony. Further comparative studies are warranted to refine indications and validate long-term outcomes. (1) Genioplasty with symphysis resection and soft tissue suspension is a safe and effective alternative to conventional techniques for correcting long and prominent chins, offering aesthetic and functional results when standard genioplasty is insufficient. (2) 3D imaging and CAD/CAM surgical guides enhance precision, reduce intraoperative risks, especially nerve injury, and are recommended for complex asymmetric patients and resections exceeding 5 mm. (3) Soft tissue suspension is essential for optimal outcomes. Proper muscular reattachment (mentalis, platysma, digastric, and optionally geniohyoid/genioglossus) reassures long-term soft tissue adaptation and aesthetic results.Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
- Research Article
- 10.14436/2358-2782.11.3:e252537.oar
- Oct 1, 2025
- Journal of the Brazilian College of Oral and Maxillofacial Surgery
- Bruna Ribeiro + 4 more
Introduction: Facial feminization surgery (FFS) plays a crucial role in gender-affirming care, particularly when addressing mandibular shape. While genioplasty is commonly performed to reduce chin prominence, it often neglects the mandibular structure, potentially resulting in an undesired square appearance and contributing to gender-related dysphoria. Case Report: We present the case of a 20-year-old transgender woman who underwent revision surgery following an unsatisfactory genioplasty. The patient reported significant psychological distress linked to her facial appearance. A new...
- Research Article
- 10.54995/asc.5.2.1
- Sep 30, 2025
- Kapadokya Üniversitesi
- Fatih Celebi + 2 more
Objective: The aim of this study was to determine the cephalometric variables that can predict the treatment success of Twin Block appliance in patients with skeletal class II divison 1 malocclusion. Materials and Methods: The patients who were treated with the Twin Block applian-ce were recruited from the archive of the clinic. They were divided into 2 groups as success and failure according to the change in ANB angle. By the 6th month after treatment, patients with a change in ANB angle of 3º or more were included in the success group (14 patients; 7 females, 7 males). Patients with a change of 1º or less were included in the failure group (14 patients; 5 females, 9 males). Seventy-five variables were measured on the pre-treatment lateral cephalograms and the groups were compared. For each variable that showed a statis-tically significant difference between the two groups, the percentage of correct classifications was calculated. Results: Of the seventy-five variables, fifteen showed a statistically significant diffe-rence between the two groups (p < 0.05). The percentages of correct classification ability of the variables varied between 82% and 57%. The variables with the highest classification suc-cess were as follows: Pg-NB (mm) (82.1%), U1NA (°) (78.6%), and L1-NB (mm) (75%). Conclusions: The variables with the highest predictive ability showed that patients with a prominent chin tip, protrusive upper incisors and retrusive lower incisors were more likely to be successfully treated with Twin Block appliance.
- Research Article
- 10.17116/plast.hirurgia202503112
- Sep 17, 2025
- Plastic Surgery and Aesthetic Medicine
- A.S Borisenko + 6 more
Objective. To evaluate the effectiveness of fat autografts for cervicomental rejuvenation procedures and chin augmentation. Material and methods. The study included 70 male and female patients aged 35-65 years with age-related changes in the lower third of the face, localized fat deposits in cervicomental area and insufficient chin projection between 2020 and 2024. All patients were divided into three groups: the 1st group (n=30) — medial platysmaplasty and chin augmentation with subplatysmal fat autograft; the 2nd group (n=15) — removal of Bichat’s fat and chin augmentation with fat autograft using Bichat’s fat pad; the 3rd group (n=25) — medial platysmaplasty and chin contouring with lipofilling. Results. Patients with various age-related changes in the lower third of the face and insufficient chin projection underwent cervicomental rejuvenation and chin augmentation. In case of chin augmentation with subplatysmal fat autograft, chin prominence increased by 0.6±0.2 cm after 3 months, 0.5±0.3 cm after 6 months and 0.4±0.2 cm after 12 months. In chin augmentation using Bichat’s fat pad autograft, chin projection increased by 0.5±0.2, 0.4±0.2 and 0.3±0.4 cm, respectively. In chin contouring with lipofilling, chin projection increased by 0.6±0.4, 0.4±0.2 and 0.2±0.1 cm, respectively. In the 1st group, 2 (3%) patients had uneven chin contours. There were no infectious-inflammatory complications. Conclusion. Autologous fat injections (lipofilling and fat autografts) are preferable for chin augmentation. Augmentation with subplatysmal fat autografts is a minimally invasive, safe, predictable, and long-term method for chin augmentation.
- Research Article
- 10.1007/s44162-025-00107-9
- Aug 5, 2025
- Journal of Rare Diseases
- Shagufta Shaikh + 3 more
Abstract Introduction The Nuclear Factor I X (NFIX) gene encodes a transcription factor associated with Malan syndrome (MS) and Marshall-Smith syndrome (MSS). MS-associated NFIX microdeletions or NFIX intragenic variants, primarily clustered in exon 2, show no significant genotype–phenotype correlations among the individuals except higher frequency of epilepsy and EEG abnormalities in NFIX microdeletions cases. In contrast, MSS-associated NFIX variants are distributed across exons 6–10, with recurrent intragenic deletions involving exons 6 and 7. Clinical findings We report a male child who presented with global developmental delay with intellectual disability and stranger anxiety. His craniofacial features included a long, narrow triangular face, midfacial hypoplasia, broad forehead, deep-set eyes, blue sclera, and thick everted lips. Additionally, the patient exhibited pectus excavatum, scoliosis, and lumbar lordosis. Neurological and systemic examinations were unremarkable. The proband’s non-consanguineous parents and his elder brother showed no phenotypic similarity with the proband. A unique finding in this case was the equal length of the great toe and the adjacent two toes, a previously unreported feature in MS. Genetic analysis and novel findings Whole exome sequencing (WES) identified a novel heterozygous de novo single-base deletion in exon 6 of the NFIX gene (NM_001365902.3):p.(Thr275Profs*49), leading to a frameshift that introduces a premature stop codon after 49 incorrect amino acids, likely subjecting the transcript to degradation via nonsense-mediated decay. Notably, our proband exhibited phenotypic variability as compared with the commonly described MS phenotype. His birth weight, length, and occipitofrontal circumference were all below the 3rd percentile, which deviates from the MS phenotype. Furthermore, macrocephaly, prominent chin, down-slanting palpebral fissures, short nose, anteverted nares, hypotonia, and advanced bone age were absent. Conclusion Our proband had anthropometric measurements below the 3rd percentile along with phenotypic heterogeneity within MS and introduced a novel foot anomaly. A reassessment of the previously reported cases could provide deeper insights into the genetic and developmental mechanisms contributing to these distinct features.
- Research Article
- 10.3389/fpsyt.2025.1481739
- Mar 5, 2025
- Frontiers in psychiatry
- Marta Kożybska + 5 more
Class III malocclusion represents one type of anterior malocclusions, characterised by a longer face and a more prominent chin. Class III malocclusions are a type of malocclusion related to the relationship between the maxilla and mandible. They are often characterized by mandibular protrusion relative to the maxilla, and in some cases, features such as elongation of the lower facial third or a more prominent chin may also be present. Due to their appearance, patients experience a range of psychosocial and emotional difficulties, which have also been identified as risk factors for problematic internet use (PIU), including depression, negative body image, and lower self-esteem. A cross-sectional study was conducted and 170 fully completed questionnaires were obtained, 85 from people with Class III malocclusions aged between 18 and 42 years, and 85 from individuals without Class III malocclusions aged between 18 and 40 years. Participants with Class III malocclusions obtained statistically significantly more PIU points than participants without Class III malocclusions (p < 0.001). Among people with Class III malocclusions 45.9% showed a high or very high risk of Internet addiction, while in the comparison group, it was only 9.4% (p < 0.001). Among participants with Class III malocclusions, there was a statistically significant, although weak, correlation between the PIU score and feeling uncomfortable when being the centre of attention (rho = 0.284; p < 0.01), and between the PIU score and concern with appearance (rho = 0.272; p < 0.05). Individuals with Class III malocclusion are at a much higher risk of problematic Internet use than people without the disorder. This problem especially concerns patients who feel discomfort when being the centre of attention and are more concerned about their appearance. Therefore, it seems that people suffering from disorders that cause changes in appearance should have access to extensive psychological support, including the prevention of problematic Internet use.
- Research Article
- 10.4041/kjod24.152
- Oct 23, 2024
- Korean journal of orthodontics
- Pareeya Yongwongsoontorn + 1 more
To evaluate the ideal anteroposterior position of incisors in lateral smiling profiles with different chin prominences and to relate these positions to nose and chin landmarks based on the perceptions of orthodontists and laypersons. A lateral smiling profile image of a female subject was adjusted to create five levels of chin prominence (-6, -3, 0, +3, +6 mm). For each level, the anteroposterior positions of the maxillary incisors were adjusted across five positions (-4, -2, 0, +2, +4 mm). Thirty-six orthodontists and 36 laypersons rated the attractiveness of each profile using a visual analog scale. The maxillary incisor position (U1) was measured relative to the external nose and chin landmarks (E-lines). Differences in perceptions between orthodontists and laypersons were analyzed. For profiles with 6 and 3 mm chin retrusion, the most favored incisor positions were the 2 mm retrusion and unaltered positions, respectively. For the unaltered chin prominence, orthodontists preferred unaltered incisors, while laypersons favored 2 mm protrusion. Conversely, for 3 and 6 mm chin protrusion, both groups preferred 4 and 2 mm protrusion, respectively. The distance between U1 and the E-line is the most attractive images ranged from 8.5 to 11.5 mm. Based on the regression model, an optimal U1-E-line distance of 8.95 mm was recommended. The preferred incisor position is influenced by chin prominence, with the incisor position shifting in the same direction as the chin. The U1 E-line can be a useful clinical tool for determining the proper incisor positioning. Esthetic perceptions were generally consistent between orthodontists and laypersons.
- Research Article
- 10.1097/scs.0000000000010269
- May 10, 2024
- The Journal of craniofacial surgery
- Sung Gyun Jung + 2 more
The authors introduce a short story about the lifestyle of a cleft lip woman in Korea, published in 1936, about 2 decades before Dr Millard operated on his first patient in Korea. A short story entitled "Ugly Thing," written by Yao-hsieh Chu, analyzed by Eonnyeon, a girl born in a rural area with a cleft lip and palate who excelled at household tasks such as sewing. Her forehead was bulging, and her eyes were protruding. She had a low-profile nose with wide nostrils. She had a left unilateral complete primary cleft, including an alveolar cleft. There was midface retraction, accompanied by a relatively prominent chin. Her voice exhibited hypernasality. People often laugh when they see Eonnyeon eating her food, exclaiming, "She's eating like a rabbit!" However, she married a young man who deserted her on their wedding night because of her appearance. Subsequently, she moved to an urban area and found work as a housemaid. One day, she was raped by a middle-aged water delivery man, who then fled. Ten months later, she gave birth to a girl who also had a cleft lip. In a moment of despair, Eonnyeon attempted to smother her baby with a pillow but stopped herself. She resolved to raise her daughter despite the challenges ahead. The mockery directed at her could be viewed as an expression of the latent sadism inherent in human nature. It is remarkable to consider the progress made since Millard performed his first cleft lip surgery in Korea in 1954.
- Research Article
- 10.17656/sdj.10183
- Apr 1, 2024
- Sulaimani Dental Journal
- Havana Nadir + 1 more
Objective: This retrospective comparative cephalometric study aims to identify the cephalometric features of skeletal class II malocclusion in a sample of the Kurdish population, the result of this study willl be useful in diagnosing and treating orthodontic and jaw surgery. Methods: A total of 85 pre-treatment lateral cephalometric radiographs with skeletal class II malocclusion (ANB>=4) and 81 with skeletal class I malocclusion (1=<ANB<4) were obtained from the pre-orthodontic patient records in a private orthodontic clinic in Sulaimani city. The patients were between 18 and 35 years old. The lateral cephalometric radiographs were analyzed digitally using FACAD cephalometric software. Twenty-two variables were measured from each cephalometric radiograph. The correlation between Class I and II was analyzed using the Mann-Whitney Test. Results: The result showed that the values of SNA, ANB, Y-axis, Convexity angle, Gonial angle, Intermaxillary angle, facial angle and FMA, posterior cranial base, effective maxillary length, LAFH were higher in skeletal Class II than in Class I cases, which indicates that skeletal class II Kurdish population have more vertical mandibular growth and prognathic maxilla, retrognathic mandible, and longer face than class I. Meanwhile, SNB, Mandibular length, TFH, UAFH, Maxillary length, UI-Palatal plane angle, IMPA, and effective mandibular length values were lower and the difference was statistically significant in the majority of cases.This illustrates that the incisors are more proclined in class I than skeletal class II, whereas the mandible is shorter in skeletal class II patients. These results summarize the characteristic features of skeletal class II patients in a sample of the Kurdish population in Sulaimani City, which are caused by etiological factors (genetic, congenital). This information is useful for enabling orthodontists and maxillofacial surgeons to attain a diagnosis and treatment plan for skeletal class II patients in a shorter period. Conclusions: Skeletal class II malocclusion in the Kurdish population is characterized by a prognathic but short maxilla, retrognathic, short, backward, and downward rotated mandible, and a prominent chin.
- Research Article
- 10.1097/gox.0000000000005725
- Apr 1, 2024
- Plastic and Reconstructive Surgery - Global Open
- Toshitsugu Hirohi
Summary: There are various types of chin deformities, and the least established surgical method for deformity correction may be reduction for anteroposterior macrogenia. Anteroposterior macrogenia is commonly corrected by either setback genioplasty or burring reduction, but these approaches are less likely to produce aesthetically pleasing results. Both procedures have poor reduction effects because of the low response rate of soft tissues to skeletal alterations. There is a high likelihood of chin ptosis and flattening. Setback genioplasty can also yield step deformities at the inferior mandibular border. To overcome these drawbacks of conventional methods, I developed a novel technique of coronal-splitting reduction genioplasty. I have performed more than 83 procedures with a high success rate over the past 10 years. Alloplastic chin implant-shaped bone fragments were resected from the prominent bony chin, in which the average thickness of resected bone was 8.2 mm. Sufficient sagittal reduction effects were then achieved in most cases, although the soft tissue response rate remains 25%–50%, as reported in the literature. The no-degloving technique with cephalic suspension of the mentalis muscle prevents chin ptosis. Combined bilateral oblique osteotomies of the inferior mandibular border contribute to minimizing obvious postoperative chin flattening. Moreover, macrogenia can be large in multiple planes, including anteroposterior, vertical, transverse, or their combinations. This new technique can handle all three planes by combining both bilateral oblique osteotomies of the inferior mandibular border and burr ostectomy. Overall, these findings suggest that the coronal-splitting genioplasty method may replace conventional methods for correcting macrogenia.
- Research Article
4
- 10.4274/turkjorthod.2023.2022.20
- Mar 1, 2024
- Turkish Journal of Orthodontics
- Philippe Farha + 2 more
To compare soft tissue profile variations between Class I and Class II adult patients due to three vertical skeletal facial patterns (normodivergent, hypodivergent and hyperdivergent) and determine which skeletal variation has the most significant impact on soft tissue profile. Retrospective soft tissue profile analysis was performed on lateral cephalograms of 131 adult patients. The analysis was divided into two categories correlated with subnasal and general soft tissue profiles. The sample was divided based on two sagittal skeletal patterns (Class I and II) and three vertical groups. In addition, comparisons were made between males and females. Viewbox 4 was used for the analysis. Descriptive, comparative, and correlation statistics were performed using SPSS software. Statistically significant inter-gender differences were found at the subnasal profile level, but not at the general profile level. No significant differences were observed when comparing subnasal profiles for the sagittal groups. However, significant differences were observed at the level of the general profile, especially at the level of Z-angle, lower lip, and chin prominence. In the vertical groups, hyperdivergent facial patterns had significant differences at the level of subnasal and general profiles compared with other vertical facial patterns. Females had more convex subnasal profiles than males. Hyperdivergent facial patterns had an impact on both general and subnasal soft tissue profiles. The sagittal dimension affected only the general soft tissue profile. Therefore, changes in the vertical dimension had the greatest impact on facial esthetics.
- Research Article
4
- 10.1016/j.ortho.2023.100842
- Jan 12, 2024
- International Orthodontics
- Monika A Hersberger-Zurfluh + 5 more
This study aimed to discover the genetic and environmental factors that contribute to the mandibular development of untreated monozygotic and dizygotic twins. The sample, taken from the Forsyth Moorrees Twin Study, included 52 untreated monozygotic twins (36 male, 16 female) and 46 untreated dizygotic twins (23 male, 23 female). At the ages of 12 and 17, lateral cephalograms were collected and traced to assess total mandibular length, mandibular ramus length, mandibular corpus length, gonial angle, SNB, and bony chin prominence. The genetic and environmental components of variation were assessed using multilevel mixed-effects structural equation modelling. At 12 years of age, high additive genetic influences were observed for total mandibular length (74%), gonial angle (76%), SNB (41%), and bony chin prominence (64%), whereas strong dominant genetic components were observed for corpus length (72%), and mandibular ramus length was under unique environment influence (54%). At 17 years of age, only total mandibular length (45%), ramus length (53%), gonial angle (76%), and bony chin prominence (68%) were under strong additive genetic control, while the remainder were under strong dominant genetic control. Although monozygotic and dizygotic twins share at least a portion of their DNA, additive, dominant, or environmental components were discovered during adolescence. Nonetheless, by the age of 17, the majority of the mandibular traits are under either additive or dominant genetic impact.
- Research Article
- 10.18231/j.jco.2023.032
- Oct 15, 2023
- Journal of Contemporary Orthodontics
- Randheer Meena + 5 more
This study was aimed to determine and compare soft tissue cephalometric norms between male and female population of Jaipur and compare them with Arnett’s soft tissue cephalometric norms with 50 males and 50 females which fall under selected inclusion criteria. One hundred samples (50 males and 50 females) were selected on random basis with harmonious facial appearances, good functional occlusions and first permanent molars in Angle's class I relation. Samples selected for the study were of age group between 18 to 25 years. Measurements were recorded and subjected to statistical analysis. 1.Cephalometric norms using Arnett's Soft tissue Analysis were established formales and females of Jaipur population. 2. Soft tissue cephalometric values show Sexual dimorphism with all the soft tissue thicknesses and the facial lengths being greater in males indicating longer faces, long upper & lower lips for males and more prominent the midfacial region in Jaipur females compared to males with more protrusive mandibular dentition with a prominent chin.
- Research Article
5
- 10.1016/j.bjoms.2023.08.213
- Sep 12, 2023
- The British journal of oral & maxillofacial surgery
- Noura M Alotaibi + 3 more
Facial appearance significantly affects psychosocial wellbeing, and an improvement in facial aesthetics is considered an essential outcome of orthognathic treatment. The surgery-first approach (SFA) has emerged as a promising alternative to the conventional orthodontics-first approach (OFA) due to its potential advantages in reducing treatment duration and cost, delivering early aesthetic improvement, and increasing patient satisfaction. However, its impact on final facial aesthetics and how it compares with the OFA has, to our knowledge, not yet been investigated. This retrospective study aimed to compare the improvement in facial aesthetics after orthognathic surgery in an SFA and an OFA group. Preoperative and postoperative 3-dimensional stereophotogrammetry facial images of 40 patients were evaluated by five professional assessors using the Global Aesthetic Improvement Scale (GAIS). Similar aesthetic improvement outcomes were found in both the SFA and OFA groups. The GAIS score significantly correlated with the following facial variables: upper lip projection, chin prominence, facial proportions, paranasal hollowing, lip competence, mandibular projection, and facial profile. No significant correlation was found between a change in aesthetic score and the surgical variables. There was a positive association between overall GAIS score and the gender and experience level of the individual assessors. This study suggests that aesthetic facial improvement achieved with the SFA is satisfactory and comparable to that of the OFA.
- Research Article
2
- 10.15406/jdc.2023.07.00245
- Sep 8, 2023
- Journal of Dermatology & Cosmetology
- Layla Dias + 2 more
Purpose: This study aims to present a clinical case of significant reduction in submental fat using the Endolifting®technique and the 1470nm diode laser, supported by an extensive literature review. Case report: The ongoing quest for innovative and minimally invasive aesthetic procedures has propelled research in the field of aesthetic dermatology. Submental fat reduction, commonly referred to as a double chin, is a prevalent aesthetic concern that impacts facial harmony and the self-esteem of many patients. In this clinical case report, we introduce the application of the 1470nm diode laser in combination with the Endolifting®technique as a non-surgical alternative for double chin reduction. A 45-year-old patient with a prominent double chin performed a single treatment session. Following the treatment, a noticeable reduction in submental fat was observed, resulting in a more balanced and rejuvenated facial profile. The patient reported an enhancement in self-esteem and satisfaction with the outcomes. Conclusion: This case report validates the effectiveness of the 1470nm diode laser and the Endolifting®technique in reducing double chin, showing it as an innovative, efficient, safe, and replicable approach for submental fat reduction.
- Research Article
1
- 10.1111/pai.13944
- Apr 1, 2023
- Pediatric Allergy and Immunology
- Anna Peirolo + 7 more
<scp>Hyper‐IgE</scp> syndrome presenting with early life craniosynostosis in monozygotic twin sisters
- Research Article
6
- 10.1016/j.jobcr.2023.02.014
- Jan 1, 2023
- Journal of Oral Biology and Craniofacial Research
- Afrah Khazal Al Hamdany + 3 more
PowerScope 2 is a fixed functional appliance for patients with Class II malocclusion and a retrognathic mandible, that has recently received attention due to its pronounced advantages, for both orthodontists and patients.Objectiveof study: This study evaluated the action of the PowerScope 2 appliance for correcting Class II malocclusion and the stresses and displacement of the mandible during loading using three-dimensional finite element analysis (FEA). The sites of the mandibular skeletal and/or dental corrections were also distinguished.Materials and methodsUsing the AutoCAD (2010) Program, a 3D model of the human mandible with teeth was created based on a CT image of a 20-yr-old patient. Orthodontic stainless-steel brackets with Standard Edgewise (0.022 in) slots bonded to five mandibular teeth and inserted into a bounded tube on the first molar were simulated. A rectangular archwire (0.019 × 0.025 in) ligated the brackets. The created models were uploaded to the Autodesk Inventor Professional Computer Program (FE) version (2020).ResultsThe FEA presented the three-dimensional results qualitatively and quantitatively as von Mises stress and displacement. The colour ruler on the upper left side demonstrates the stress and displacement distribution pattern of the mandible, with the minimum value in blue and the maximum value in red. Mandibular movement was achieved three-dimensionally. There was obvious sagittal forward mandibular movement, and high stress was observed at the chin prominence (the pogonion). In the transverse plane, the mandible was highly bent buccally, especially at the gonial angle and antegonial notch. In the vertical plane, the highest ranges of mandibular movements were seen in the chin, the anterior part of the mandibular body, and the associated dentoalveolar region.ConclusionsThe results of this FEA, PowerScope 2 functional appliance proved to be effective as a Class II malocclusion corrector. Its mode of action on the mandible was achieved in three planes of space, and its orthodontic effects were gained dentally and skeletally. An bbvious sagittal forward mandibular movement was observed, particularly at the chin prominence. Apparent buccal bending, especially at the gonial angle and antegonial notch, was observed. Vertically, the chin and anterior part of the mandible, with the associated dentoalveolar structures, were clearly stressed under the action of this appliance.
- Research Article
4
- 10.1080/17446651.2022.2144229
- Nov 2, 2022
- Expert Review of Endocrinology & Metabolism
- Andrea D’Souza + 2 more
ABSTRACT Introduction The use of facial recognition technology has diversified the diagnostic toolbelt for clinicians and researchers for the accurate diagnoses of patients with rare and challenging disorders. Specific identifiers in patient images can be grouped using artificial intelligence to allow the recognition of diseases and syndromes with similar features. Lysosomal storage disorders are rare, and some have prominent and unique features that may be used to train the accuracy of facial recognition software algorithms. Noteworthy features of lysosomal storage disorders (LSDs) include facial features such as prominent brows, wide noses, thickened lips, mouth, and chin, resulting in coarse and rounded facial features. Areas covered We evaluated and report the prevalence of facial phenotypes in patients with different LSDs, noting two current examples when artificial intelligence strategies have been utilized to identify distinctive facies. Expert opinion Specific LSDs, including Gaucher disease, Mucolipidosis IV and Fabry disease have recently been distinguished using facial recognition software. Additional lysosomal disorders LSDs lysosomal storage disorders with unique and distinguishable facial features also merit evaluation using this technology. These tools may ultimately aid in the identification of specific LSDs and shorten the diagnostic odyssey for patients with these rare and under-recognized disorders.
- Research Article
- 10.5812/ijp-117984
- Aug 21, 2022
- Iranian Journal of Pediatrics
- Golnaz Ghazizadeh Esslami + 3 more
Introduction: A 6-year-old boy was referred to our hospital because of the stiffness of both knees, which had commenced two years ago and gradually progressed to both hips, ankles, elbows, fingers, and toes. He occasionally had arthralgia with no complaint of joint swelling. He had a long face, a prominent forehead and chin, and a short neck. There was a limitation in the range of motion in all appendicular joints with stiffness and deformity. Case Presentation: Skeletal survey images revealed central beaking and a bullet shape appearance in the cervical and lumbar vertebra, tapering of iliac wings, deformity of the femoral head, and short sacral length. A +3 glycosaminoglycan (GAG) excretion was detected in the urine test, but genetic analysis revealed Mucolipidosis type III. Conclusions: The diagnosis of metabolic diseases should be considered whenever there is joint stiffness without any evidence of inflammation. Mucopolysaccharidoses and Mucolipidoses are progressive storage disorders with many clinical and radiological characteristics.
- Research Article
1
- 10.4103/jdrntruhs.jdrntruhs_19_21
- Jul 1, 2022
- Journal of Dr. NTR University of Health Sciences
- Agrima Thakur + 1 more
Background: The success of orthodontic treatment to a significant extent is largely dependent on the patient's and lay peoples' perception. Treatment can influence the soft tissue profile of the face, which is why, it is important for orthodontists to perceive what is considered attractive and unattractive amongst locals, and further, incorporate this knowledge in their diagnosis and treatment planning for population-specific groups. Aim: To evaluate differences in perception of attractiveness of the human face (in profile view) among ethnic Telangana subjects when compared to ideal Caucasian facial profile attractiveness standards. Methods: Profile silhouettes of ethnic Telangana subjects with straight, convex and concave facial profiles were rated by 10 adult laypersons (ethnic Telangana origin) and scored from least to most attractive. Fifteen relevant soft-tissue parameters from the Ricketts, Legan-Burstone, Steiner's and Z-Merrifield analysis were then evaluated on lateral cephalometric radiographs of the highest scoring subjects (considered most attractive) and sample t test statistical analysis was done in order to investigate differences between obtained values of the 'attractive' group as compared to standard values given in these analyses. Results: Of 15 parameters compared, significant differences from standard cephalometric values were evident for- vertical lip-chin ratio, lower lip protrusion, mento-labial sulcus and Z- angle. These measurements were smaller in the evaluated population group as compared to orthodontic norms. Conclusion: People of ethnic Telangana origin considered a shorter and less prominent lower lip and chin and a shallower mento-labial sulcus to be more attractive, as compared to standard orthodontic cephalometric norms of Caucasian populations.