Procrustes Analysis Research Articles

The Slavcleft: A Three-Center Study of the Outcome of Treatment of Cleft Lip and Palate Considering Palatal Shape.

The degree of deviation of palatal shape from the norm may reflect facial growth disturbance in cleft lip and palate (CLP). The objective of this study was to compare the palatal morphology in children treated with different surgical protocols. Palatal shape was assessed with geometric morphometrics (GM) including Procrustes superimposition, principal component analysis (PCA), and permutation tests with 10,000 permutations, in 24 children treated with two-stage repair with a late palatoplasty (Prague group; mean age at assessment 8.9 years), 16 children after two-stage repair with early palatoplasty (Bratislava group; mean age 8.2 years), and 53 children treated with a one-stage repair (Warsaw group, mean age 10.3 years). The non-cleft control group comprised 60 children at 8.6 years. The first five principal components (PCs) accounted for a minimum of 5% of the total shape variability (65.9% in total). The Procrustes distance was largest for the Prague vs. Control pair and smallest for the Prague vs. Bratislava pair. Nonetheless, all intergroup differences were statistically significant (p < 0.01). One can conclude that variations in palatal shape roughly correspond to cephalometric and dental arch relationship findings from prior research. Among the children who underwent a one-stage repair of the complete cleft, their palatal morphology most closely resembled that of the non-cleft controls. Conversely, children who received late palatoplasty exhibited the greatest degree of deviation.

Evaluation of the hoof centre-of-pressure path in horses affected by chronic osteoarthritic pain.

The Centre of Pressure (COP) is the single point summarising all forces transferred to the hoof during the stance phase of a stride. COP path (COPp) is the trajectory that COP follows from footstrike to lift-off. Aim of the present study was to characterize the COP and COPp in horses affected by osteoarthritis and chronic lameness. Seventeen adult horses with a diagnosis of osteoarthritis and single limb chronic lameness were recruited. The COP was recorded using a wireless pressure measuring system (TekScan®) with sensors taped to the hooves (either fore- or hind limb, depending on lameness location). The COPp coordinates were further processed. Procrustes analysis was performed to assess the variability of single strides COPp and average COPp among strides, gaits, and limbs by calculating Procrustes distances (D-values). A linear mixed-effects model was run to analyse D-values differences for lame and sound limbs. Additionally, average COPp D-values and COPp hoofprint shape indices were compared for lame and sound limbs with the Signed Rank Test. At walk and trot the single-stride COPp D-values were significantly lower in lame than in sound limbs (marginal effects p<0.001). Analysis of the average COPp D-values confirmed that each hoof COPp is highly consistent with itself over subsequent trials but is different from the contralateral. COPp and hoofprint shape indices did not differ between sound and lame limbs. Footstrike and lift-off within the hoofprint showed that most horses had lateral footstrike and lift-off, independently of the lameness location. Our findings are in line with previous observations that COPp are highly repetitive and characteristic for each horse and limb. There seems to be a further decrease in COPp variability in the presence of a painful limb pathology.

Size and shape of human mandible: Sex differences and influence of age on sex estimation accuracy

The degree of sexual dimorphism expressed by human bones is of primary importance for the development of accurate methods for sex estimation. The objective of the present study was to investigate sex differences in shape and size of the mandible using geometric morphometric methods. The study also aimed to examine the impact of age on the sex classification ability of the size and shape of the mandible. Computed tomography images of 190 Bulgarians (98 males and 92 females) were used in the study. Polygonal surface models of the skulls were generated and used for digitizing 45 landmarks located on the mandible. The raw three-dimensional coordinates of the landmarks were processed via generalized Procrustes superimposition. The sex differences in mandibular size and shape were evaluated for statistical significance. Multivariate regression was applied for correction of the allometric effect. Principal component analysis, discriminant analysis, and canonical variate analysis were also used in the study. Mandibular size differed significantly between males and females and achieved a sex classification accuracy of 87%. The significance of the sex differences in mandibular shape depended on the type of shape variables used in the analysis. The shape variables provided different classification accuracy: 78% using the Procrustes coordinates and 53% using the regression residuals. The male and female mandibles differed significantly in size and shape, including the allometric component. Mandibular size is a more effective sex indicator than shape. Age has an ambiguous effect on the classification accuracy of the size and shape variables of the mandible.

A new spike-in-based method for quantitative metabarcoding of soil fungi and bacteria.

Metabarcoding is a powerful tool to characterize biodiversity in biological samples. The interpretation of taxonomic profiles from metabarcoding data has been hindered by their compositional nature. Several strategies have been proposed to transform compositional data into quantitative data, but they have intrinsic limitations. Here, I propose a workflow based on bacterial and fungal cellular internal standards (spike-ins) for absolute quantification of the microbiota in soil samples. These standards were added to the samples before DNA extraction in amounts estimated after qPCRs, to target around 1-2% coverage in the sequencing run. In bacteria, proportions of spike-in reads in the sequencing run were very similar (< 2-fold change) to those predicted by the qPCR assessment, and for fungi they differed up to 40-fold. The low variation among replicates highlights the reproducibility of the method. Estimates based on multiple bacterial spike-ins were highly correlated (r = 0.99). Procrustes analysis evidenced significant biological effects on the community composition when normalizing compositional data. A protocol based on qPCR estimation of input amounts of cellular spikes is proposed as a cheap and reliable strategy for quantitative metabarcoding of biological samples.

Geometric Morphometric Analysis of the Condylus Occipitalis and Foramen Magnum in Sheep and Goat

Aim: The aim of this study was to reveal the dimorphic structures of the foramen magnum and condyle occipitalis through an interspecies shape analysis and to determine the variability between sheep and goats. Materials and Methods: The study includes data from 81 skulls (46 sheep and 35 goat) for this aim. The foramen magnum frame shape and the condyle occipitalis variation were determined using type I (anatomical) and type III (semilandmarks). Results: Accordingly, was determined 30.76, 14.94 and 14.07 of the total shape variation of PC1, PC2 and PC3, respectively. It was determined that condylus occipitalis was primarily responsible for the shape variation according to PC1, and foramen magnum was responsible for the secondarly. It was found to explain the shape variation of the right condyle occipitalis to a great extent compared with PC2, while in PC3, it caused the entire right condyle occipitalis to explain the shape variation of the extreme lateral corner of the left condyle occipitalis and the left edge of the foramen magnum. The discriminant function analysis determined the Procrustes and Mahalanobis distances to be 0.12293879 (p &lt; 0.0001) and 67.7482 (p &lt; 0.0044), respectively. Conclusion: As a result, the geometric morphometry method is regarded to be a useful tool for detecting changes in skull shape between species and can thus be used successfully for taxonomic, archaeological, and forensic research.

Uncovering untapped potentials: diversifying business may yield profitable earnings, yet it remains an overlooked strategy among beekeepers

Beekeeping is a rewarding business that offers numerous opportunities beyond just honey production. While most beekeepers are solely focused on honey production, this approach can be limiting due to the fluctuation of weather and market conditions. Therefore, it is essential to diversify your business by exploring other honey bee products and services. Our research investigated the beekeeping practices of 100 beekeepers from seven regions in southern Brazil to identify the most common practices and potential opportunities for diversification. Our study focused on ten major beekeeping practices, including products or services as honey, queen rearing, swarm, propolis, pollen, beeswax, royal jelly, sanitary control activity, digital technology enthusiasm, and migratory beekeeping. We used a semi-structured questionnaire consisting of 86 questions that were analysed with generalized Procrustes analysis and clustered heatmap. Overall, we found that honey production, digital technology enthusiasm, and migratory beekeeping are the most common beekeeping practices among beekeepers, regionally. Conversely, the exploitation of beeswax, pollen, swarm, and royal jelly production were relatively rare, creating opportunities for beekeepers looking to diversify their earnings and reduce competition. Additionally, our research revealed that certain regions have adopted specific beekeeping practices better than others, which suggests that there are possibilities for improvement and growth in the beekeeping industry. Finally, our research demonstrates the potential for beekeepers to diversify their business beyond just honey production. By exploring other honey bee products and services, beekeepers can reduce the impact of market limitations caused by weather and market fluctuations, ultimately creating a more resilient and profitable business.

Variations in Otolith and Scale Shape of the Invasive Round Goby Neogobius melanostomus Populations from Different Habitats of the Sava River Basin, Croatia

Abstract Round goby Neogobius melanostomus is one of the three invasive Ponto-Caspian gobies found in the Sava River basin in Croatia. It has a negative effect on the native ecosystems due to its high invasive potential that enables its rapid spread upstream in inland watercourses. The objective of this study was to determine the differences in sagittal otolith and scale shape of the frontal and established populations of N. melanostomus in two different habitat types. At two sampling sites in the main course of the Sava (Babina Greda, Slavonski Brod) and in a modified habitat (Sava-Odra canal), 20 individuals of N. melanostomus were collected and analysed. The geometric morphometric method was used together with Procrustes analysis of variance, canonical variate analysis and discriminant function analysis to analyse the otolith and scale shape. Significant differences in both otolith and scale shapes were found between settled (Babina Greda) and frontal (Slavonski Brod) populations from the main course of the Sava River. The main differences were the wider anterior part of the scales and a more pronounced open indentation on the otolith of the Babina Greda population. The settled population in the Sava-Odra canal was significantly different in otolith shape from the Babina Greda population but not from the Slavonski Brod population, suggesting that the upstream migration consisted of individuals with specific phenotype and genotype. Otoliths generally expressed greater shape variability than scales and thus may be more useful for differentiating between closely related populations on a finer scale. The results of this study suggest that the shape of otoliths and scales can be used to distinguish between closely related populations of N. melanostomus from different habitats but more comprehensive studies are needed due to the small number of samples.

Extraction and analysis of flow features in planar synthetic jets using different machine learning techniques

Synthetic jets are useful fluid devices with several industrial applications. In this study, we use the flow fields generated by two synchronously operating synthetic jets and simulated using direct numerical simulations. These flow fields are characterized by a jet Reynolds number, Re=100, 150, and 200, and a Strouhal number, St=0.03. We benchmark four different dimensionality reduction techniques: (1) higher-order dynamic mode decomposition (HODMD), (2) proper orthogonal decomposition, (3) vector quantization via principal component analysis (VQPCA), and (4) linear autoencoders. These techniques are often used in generating reduced-order models (ROMs). The performances of these techniques are compared (i) in terms of their ability to accurately reconstruct the high-dimensional flow fields from their low-dimensional manifolds and (ii) in terms of their ability to extract meaningful low-dimensional patterns/features/structures that best describe the main dynamics of the synthetic jets. The similarity between the extracted features is also quantitatively assessed with the help of Procrustes analysis, showing how manifolds from different techniques become more similar when a larger number of modes are retained. Accurate reconstruction and model complexity (or interpretability) are often two counter-balancing objectives. In this comparative study, we found that among the four techniques, VQPCA has clear advantages for developing accurate ROMs, while HODMD is useful for understanding the dynamics of synthetic jets, providing additional information that is not readily available with other methods.

Three-dimensional assessment of facial asymmetry in class III subjects, part 2: evaluating asymmetry index and asymmetry scores.

To evaluate the outcomes of corrective surgical treatment for craniofacial asymmetry using four different methods with the aim of developing the best technique for craniofacial asymmetry assessment. CBCT images of twenty-one class III subjects with surgically corrected craniofacial asymmetry and twenty-one matched controls were analyzed. Twenty-seven hard tissue landmarks were used to quantify asymmetry using the following methodologies: the asymmetry index (AI), asymmetry scores based on the clinically derived midline (CM), Procrustes analysis (PA), and modified Procrustes analysis (MPA). Modified Procrustes analysis successfully identified pre-operative asymmetry and revealed severe asymmetry at the mandibular regions compared to controls, which was comparable to the asymmetry index and clinically derived midline methods, while Procrustes analysis masked the asymmetric characteristics. Likewise, when comparing the post-surgical outcomes, modified Procrustes analysis not only efficiently determined the changes evidencing decrease in facial asymmetry but also revealed significant residual asymmetry in the mandible, which was congruent with the asymmetry index and clinically derived midline methods but contradictory to the results shown by Procrustes analysis. In terms of quantifying cranio-facial asymmetry, modified Procrustes analysis has evidenced to produce promising results that were comparable to the asymmetry index and the clinically derived midline, making it a more viable option for craniofacial asymmetry assessment. Modified Procrustes analysis is proficient in evaluating cranio-facial asymmetry with more valid clinical representation and has potential applications in assessing asymmetry in a wide spectrum of patients, including syndromic patients.

Elemental Assessments in Paddy Soil for Geographical Traceability of Rice from Peninsular Malaysia

This investigation aimed to establish the geographical traceability of Malaysian rice by assessing the elemental composition in paddy soil. Multi-element determination in combination with a chemometric approach was applied to evaluate the elemental concentrations of paddy soil from granaries cultivated with the same rice variety and to assess the relationship between elements in the soil and rice (SAR) system. A total of 29 elements (aluminum, arsenic, barium, bromine, calcium, chlorine, cobalt, chromium, cesium, europium, iron, gallium, hafnium, potassium, lanthanum, lutetium, magnesium, manganese, sodium, rubidium, antimony, scandium, samarium, thorium, titanium, uranium, vanadium, ytterbium and zinc) were successfully determined in paddy soil from Kedah, Selangor and Langkawi by neutron activation analysis. A significant difference (P < 0.05) between 18 elements in the soil samples was obtained. The chemometric approaches of principal component and linear discriminant analyses demonstrated clear discrimination and highly corrected classification (100%) of the soil samples. A high classification (98.1%) was also achieved by assessing 10 elements (aluminum, arsenic, bromine, chlorine, potassium, magnesium, manganese, sodium, rubidium and zinc), which similarly applied to rice geographical origin determination. Similar elements in SAR were also observed for differences in the pattern of correlation and bioaccumulation factor between the granaries. Furthermore, the generalized Procrustes analysis showed a 98% consensus between SAR and clear differences between the studied regions. The canonical correlation analysis demonstrated a significant correlation between the chemical profile of SAR (r2 = 0.88, P < 0.001). Therefore, the current work model provides a reliable assessment to establish rice provenance.

Regional plantar forces and surface geometry variations of a chronic ankle instability population described by statistical shape modelling

BackgroundUnderstanding detailed foot morphology as well as regional plantar forces could provide insight into foot function and provide recommendation for footwear design for chronic ankle instability (CAI) people. Research QuestionThis study presented 3-dimensional statistical shape models of feet from three different populations including CAI, copers and healthy individuals, with regional plantar forces also acquired. MethodsSixty-six males (22 participants per group) were included in this study to capture 3-dimensional foot shapes under a standing condition and regional plantar forces during a cutting maneuver. Principal component analysis was performed to generate a mean foot shape of each group as well as modes of variations. A generalized procrustes analysis was used to achieve rapid registration of mean shapes. Besides, regional plantar forces and contact duration among these three populations were compared. ResultsFor 3-dimensional foot shapes, although no significant differences of the average distance between each mode and mean shape were found among three populations, there were subtle variations in mean shapes. The CAI population presented a more bulging of the lateral malleolus; copers were characterized by the flexion of the lesser toes, a more bulging of the medial foot in the sagittal plane; and healthy individuals showed a greater heel width and a more bulging of the heel in the sagittal plane. In terms of plantar forces, healthy individuals had significantly greater summated plantar forces and greater plantar forces in the lateral heel area during the early contact phase compared to copers and CAI participants. SignificanceOverall, this study suggested that repetitive ankle sprains may lead to the bulging of the lateral malleolus. Further, CAI and copers seem to stabilize the ankle joint by medially shifting the center of pressure compared to healthy individuals under the static and less challenging dynamic conditions.

AI-based diagnosis in mandibulofacial dysostosis with microcephaly using external ear shapes.

Mandibulo-Facial Dysostosis with Microcephaly (MFDM) is a rare disease with a broad spectrum of symptoms, characterized by zygomatic and mandibular hypoplasia, microcephaly, and ear abnormalities. Here, we aimed at describing the external ear phenotype of MFDM patients, and train an Artificial Intelligence (AI)-based model to differentiate MFDM ears from non-syndromic control ears (binary classification), and from ears of the main differential diagnoses of this condition (multi-class classification): Treacher Collins (TC), Nager (NAFD) and CHARGE syndromes. The training set contained 1,592 ear photographs, corresponding to 550 patients. We extracted 48 patients completely independent of the training set, with only one photograph per ear per patient. After a CNN-(Convolutional Neural Network) based ear detection, the images were automatically landmarked. Generalized Procrustes Analysis was then performed, along with a dimension reduction using PCA (Principal Component Analysis). The principal components were used as inputs in an eXtreme Gradient Boosting (XGBoost) model, optimized using a 5-fold cross-validation. Finally, the model was tested on an independent validation set. We trained the model on 1,592 ear photographs, corresponding to 1,296 control ears, 105 MFDM, 33 NAFD, 70 TC and 88 CHARGE syndrome ears. The model detected MFDM with an accuracy of 0.969 [0.838-0.999] (p < 0.001) and an AUC (Area Under the Curve) of 0.975 within controls (binary classification). Balanced accuracies were 0.811 [0.648-0.920] (p = 0.002) in a first multiclass design (MFDM vs. controls and differential diagnoses) and 0.813 [0.544-0.960] (p = 0.003) in a second multiclass design (MFDM vs. differential diagnoses). This is the first AI-based syndrome detection model in dysmorphology based on the external ear, opening promising clinical applications both for local care and referral, and for expert centers.

Virtual trail assembly of prefabricated structures based on point cloud and BIM

During the construction of prefabricated structures, manufacturing deviations and assembly deviations will accumulate. By detecting dimensional deviations of precast concrete (PC) components, rework can be avoided. This paper presents a Scan-vs-BIM (Building Information Modeling) method based on point clouds to identify PC components and evaluate manufacturing deviations. Based on Extended Orthogonal Procrustes Analysis (EOPA), a virtual trial assembly (VTA) approach is introduced to quantify cumulative deviation between PC components and the corresponding nominal specifications. The method has been applied to a two-story prefabricated frame, and the obtained results show that the average absolute deviation and standard deviation between the structure and the BIM model were 11.55 mm, and 3.60 mm, respectively. This study presents a solution for predicting the assembly deviation of PC components, and for enhancing the quality of prefabricated structures.

Изменчивость лицевого скелета у носителей джетыасарской археологической культуры Восточного Приаралья по данным 3D геометрической морфометрии

Introduction. The origin of the Jetyasar culture’s population remains a subject of debate. It was generally accepted that the Xiongnu penetrated into the Aral Sea region and participated in the formation of the local population. Previous studies have shown a complex and admixed origin of the Jetyasar people. But the spread of the head deformation tradition in this population imposes serious limitations on the application of craniometric methods for studying Jetyasar samples. Those limitations can be potentially mitigated with the use of geometric morphometrics (GM). The purpose of this work was to assess the degree of variation in the facial skeleton of the Jetyasar people in comparison with populations of the Early Iron Age and the Hunno-Sarmatian period. Material and methods. Digital, three-dimensional models of the skulls were created. Ten landmarks were placed on each of the models and subjected to general Procrustes analysis (GPA) and principal component analysis (PCA). Results. The first PC of the analysis of the total male sample reflects variation in the height of the face, nasal bridge protrusion, and the relative width of the infraorbital region. The second component describes the height of the lateral part of the zygomatic process of the maxilla and the adjacent part of the zygomatic bone. The Kosasar 2 male sample is the most diverse morphologically. This burial ground, according to archeological data, belonged to a migrant population related to the Xiongnu. In the female total sample, high values of the first PC are associated with a tall face, a weak nasal bridge protrusion, and a long zygomatic-maxillary suture. The second PC describes the morphology of the zygomatic process of the upper jaw. The Jetyasar samples are morphologically distinct from the skulls from China, Mongolia, Western Siberia, and Southern Siberia. An exception are the crania from the burial grounds of Kosasar 2, 3, and Altyn-Asar 4t which are similar to the early Iron Age samples from China (inner Mongolia, Warring States period, 5 th – 3rd centuries BC), Mongolia (Xiongnu period), and Tuva (Arzhan-2). Discussion. The Xiongnu migration could become a catalyst for the admixture and ethnogenetic processes in the region. Conclusion. Our study shows that the population of the Jetyasar culture was morphologically heterogeneous at all stages of the culture’s development. The hypothesis about the migrant roots of a part of the population is confirmed by our data.

Geometric morphometric assessment of the fossil bears of Namur, Belgium: Allometry and ecomorphology

The Namur area in Belgium is useful to study brown (Ursus arctos) and cave bears (Ursus spelaeus) as the assemblage contains little temporal and no geographical variation. Here, we aim to assess ontogenetic allometry within cave bears, as well as ecomorphological differences between adult brown bears (n = 9), adult cave bears (n = 5) and juvenile cave bears (n = 3). Landmarks for 3D digitization of the mandible were chosen based on the taphonomical damage of the specimens. Extant brown bears and extinct Pleistocene brown and cave bears were digitized with a Microscribe G2. Generalized Procrustes superimposition was performed on the coordinates. Allometry was studied using regression analysis. Principal component analysis (PCA) was conducted to assess ecomorphological differences between the groups. 61% of the shape variance within juvenile and adult cave bears was predicted by size (n = 8, p &lt; 0.01). The juvenile cave bears have relatively deep horizontal rami. In adult cave bears, the horizontal ramus is much narrower dorsoventrally. Juvenile cave bears have a small masseteric fossa and a short coronoid process, whereas both are larger, relative to mandible size, in adult cave bears. This made juvenile cave bears likely less effective masticators than fully grown cave bears. In the PCA, principal component (PC) 1 accounts for 45.0% of the total variance and PC2 accounts for 27.6%. Fossil U. arctos from Namur fall within the 95% confidence interval of modern North American U. arctos on both PCs, but are more similar to cave bears than the average extant brown bear. From the similarity of fossil and modern brown bears, it can be deduced that the diet of fossil brown bears was probably also within the range of their modern North American conspecifics, although they might have been more efficient at masticating plant matter.

A Novel Procrustes Analysis Method to Quantify Multi-Joint Coordination of the Upper Extremity after Stroke.

Upper extremity motor impairment affects about 80% of persons after strokes. For stroke rehabilitation, upper limb kinematic assessments have increasingly been used as primary or secondary outcome measures. There is currently no universal standardized scale for categorizing multi-joint upper extremity movement. We propose a modified Procrustes statistical shape method as a quantitative analysis that can recognize segments of movement where multiple limb segments are coordinating movement. Rather than rely solely on discrete kinematic values to contrast movement, this method allows evaluation of how movement progresses. The Procrustes analysis of able-bodied movement showed that the hand and forearm segments moved in a more coordinated manner during initiation. The shoulder and elbow become more coordinated during movement completion. In impaired movement, this coordination between the hand and forearm is disrupted as the arm decelerates. The utilization of Procrustes analysis may be a step towards developing a comprehensive and universal quantitative tool that does not require changes to existing treatments or increase patient burden.Clinical relevance- This modified Procrustes Shape Analysis method can be applied by clinicians to motion capture data from patients suffering upper extremity movement deficits to objectively identify multi-joint coordination and recovery.

Evaluation of sex dimorphism of the mandible with geometric morphometric analysis: conventional and reconstructed panoramic radiography study.

The purpose of the study was to investigate the mandible shape dimorphism between males and females both on conventional panoramic radiographs (cPR) and reconstructed panoramic radiographs obtained from cone beam computed tomography (rPR) with geometric morphometric method. Panoramic radiographs and cone beam computed tomography scans were performed on 33 males and 35 females with median age 23.0 (13.0-57.0) years old. The mandibular shape comparisons between genders were examined with Procrustes analysis, mandible shape classification analysis was made with principal component analysis and shape deformations were concluded from thin plate spline (TPS) analysis. Age had no statistically significant difference between gender (p = 0.580). For the shape of mandible on cPR and rPR, there were statistically significant differences between males and females (p = 0.002, p = 0.032, respectively). The shape variabilities of mandible on cPR for females were 0.054 and for males 0.053. The shape variabilities of mandible on rPR for females were 0.051 and for males 0.049. Both on cPR and rPR, the shape variability of the females' mandible was similar within their group, the shape variability of the males' mandible was similar within their group. In the examination of mandibular dimorphism in cPR, maximal deformations were seen in the region between the mandibular notch, posterior ramus, anterior ramus, gonion, in both sides, in TPS graphs. On the other hand, a high level of deformations was observed in all landmarks that define the mandibular shape on rPR. The mandible dimorphism can be detected in the examination performed with geometric morphometric methods on cPR and rPR. While mandible shape differences according to gender are seen most in the ramus region in cPR, differences can be detected in all landmarks in rRP.

Sella turcica morphometrics in subjects with down syndrome

ObjectiveSince the number of patients diagnosed with Down syndrome seeking orthodontic treatment is increasing, clinicians could contribute by applying diagnostic modalities used frequently in the orthodontic field for research purposes. Thus, The aim of the present study is to implement morphometric methods to investigate the size and shape of sella turcica in subjects with Down syndrome. Materials and MethodsIn this retrospective study, archive records of 24 individuals with Down syndrome were compared to 48 healthy controls matched for age and gender. Parameters such as sella anterior, midpoint, and posterior height were measured, as well as sella width, area, and length were calculated. Independent sample t-tests were applied for the comparison of differences in sella turcica dimensions. Geometric morphometric analysis of the sella was performed with, implementing methods such as Procrustes superimposition and principal component analysis. Statistical significance was set at p<0.05. ResultsStatistically significant differences were found for sella anterior height, sella midpoint height, sella posterior height, sella maximum height, sella length, and sella area. All the aforementioned values were significantly increased in the Down syndrome subjects (p<0.05). Principal component analysis (PCA) depicted a statistically significant difference in sella shape between patients with Down syndrome and healthy controls (p<0.05). ConclusionsSubjects with Down syndrome presented significantly increased sella turcica dimensions as well statistically significant differences in shape compared to healthy controls.

An innovative analysis of nasolabial dynamics of surgically managed adult patients with unilateral cleft lip and palate using 3D facial motion capture

To compare dynamic nasolabial movement between end-of-treatment cleft and a matched non-cleft group in adult patients. Thirteen treated adult participants with unilateral cleft lip and palate had images taken using a facial motion capture system performing a maximum smile. Seventeen landmarks were automatically tracked. For each landmark pair, on either side of the midline, changes in the x, y, and z directions were used to analyze the magnitude of displacement and path of motion. An asymmetry score was developed at rest, mid-smile, and maximum smile to assess the shape of the mouth and/or nose. At maximum smile, displacement of right and left cheilion was clinically and statistically (p<0.05) less in the cleft group. The lip asymmetry score was greater (p<0.05) at each time point in the cleft group using the clinical midline. Using Procrustes superimposition, the differences were significant (p<0.05) only at rest and mid-smile. The alar bases were displaced significantly less (p<0.05) in the z direction in the cleft group. The asymmetry score of the alar base was significantly higher using the clinical midline than using Procrustes superimposition in patients with cleft conditions (p<0.001). In the cleft group, at maximum smile, the right and left cristae philter moved significantly less (p<0.05) in the x and z directions. There was an increase in asymmetry score of the corners of the mouth and alar bases from rest to maximum smile. The lips were similar in shape but oriented differently in the faces of patients with cleft conditions than in individuals without those conditions.

Graphical Image Rendering: Modeling, Animation of Facial or Wild Images

In this comparative study, we intend to analyse different methodologies to perform 3-Dimensional modeling and printing, by using raw images as input without any supervision by a human. Since the input consists of only raw images, the foundation of the methods is finding symmetry in images. But the images that seem symmetric are not symmetric due to the perspective effect and utterance of other factors. The method uses factors like depth, albedo, point of view, and lighting from the input image to formulate 3D shapes. A 3D template model with feature points is created, and by deforming the 3D template model, a 3D model of the subject is then reconstructed from orthogonal photos. The number and locations of the proper amount of feature points are derived. Procrustes Analysis and Radial Basis Functions (RBFs) are used for the deformation. Images are then mapped onto the mesh following the deformations for realistic visualization. Characterization of the input image shows an asymmetric cause of shading, lighting, and albedo rendering the symmetry of images. The experiments show that using these methods can give exact 3D shapes of objects like human faces, cars, and cats.