Motion Processing Research Articles

감각조절에 어려움이 있는 학령기 아동에게 전정고유활동이 시운동능력에 미치는 영향

This study investigated the effects of vestibulo-proprioceptive activities on sensory processing and visuo-motor integration in school-aged children with sensory processing difficulties. The study included one school-aged child aged 9 years, and the experiment was conducted from March to April 2022, with a total of 16 sessions held twice a week for 40 minutes each. The child’s sensory processing ability was measured using the KV-SP-2, and visuo-motor integration ability was measured using the VMI-6. To determine the effectiveness of the intervention, the results before and after the vestibulo-proprioceptive activities were compared. The results of KV-SP-2 showed that the child sought more sensory input than before. Auditory and motion processing changed from much more than peers to more than peers. Visual and tactile processing changed from similar to peers to much more than peers. Sensory-seeking behaviors changed from similar to peers to much more than peers, while attentional responses to sensory processing changed from much more than peers to similar to peer. The results of VMI-6 showed that the child’s VMI and visual perception were at an average level, but their motor coordination was slightly lower than average. Specifically, the age equivalence for motor coordination was slightly lower, at 5 years and 3 months, compared 5 years and 6 months for the other domains. In conclusion, vestibulo-proprioceptive activities hand an effect on both sensory and behavioral areas, as well as motor coordination in visuo-motor integration development, in school-aged child with sensory processing difficulties.

Associations Between Autism Spectrum Quotient and Integration of Visual Stimuli in 9-year-old Children: Preliminary Evidence of Sex Differences.

The dorsal stream vulnerability hypothesis posits that the dorsal stream, responsible for visual motion and visuo-motor processing, may be particularly vulnerable during neurodevelopment. Consistent with this, autism spectrum disorder (ASD) has been associated with deficits in global motion integration, though deficits in ventral stream tasks, such as form identification, have also been reported. In the current study, we examined whether a similar pattern of results is found in a cohort of 381 children born with neurodevelopmental risk factors and exhibiting a wide spectrum of caregiver-reported autistic traits. We examined the associations between global motion perception, global form perception, fine motor function, visual-motor integration, and autistic traits (autism spectrum quotient, AQ) using linear regression, accounting for possible interactions with sex and other factors relevant to neurodevelopment. All assessments of dorsal stream function were significantly associated with AQ such that worse performance predicted higher AQ scores. We also observed a significant sex interaction, with worse global form perception associated with higher AQ in boys (n = 202) but not girls (n = 179). We found widespread associations between dorsal stream functions and autistic traits. These associations were observed in a large group of children with a range of AQ scores, demonstrating a range of visual function across the full spectrum of autistic traits. In addition, ventral function was associated with AQ in boys but not girls. Sex differences in the associations between visual processing and neurodevelopment should be considered in the designs of future studies.

Canonical circuit computations for computer vision.

Advanced computer vision mechanisms have been inspired by neuroscientific findings. However, with the focus on improving benchmark achievements, technical solutions have been shaped by application and engineering constraints. This includes the training of neural networks which led to the development of feature detectors optimally suited to the application domain. However, the limitations of such approaches motivate the need to identify computational principles, or motifs, in biological vision that can enable further foundational advances in machine vision. We propose to utilize structural and functional principles of neural systems that have been largely overlooked. They potentially provide new inspirations for computer vision mechanisms and models. Recurrent feedforward, lateral, and feedback interactions characterize general principles underlying processing in mammals. We derive a formal specification of core computational motifs that utilize these principles. These are combined to define model mechanisms for visual shape and motion processing. We demonstrate how such a framework can be adopted to run on neuromorphic brain-inspired hardware platforms and can be extended to automatically adapt to environment statistics. We argue that the identified principles and their formalization inspires sophisticated computational mechanisms with improved explanatory scope. These and other elaborated, biologically inspired models can be employed to design computer vision solutions for different tasks and they can be used to advance neural network architectures of learning.

Zebrafish optomotor response to second-order motion illustrates that age-related changes in motion detection depend on the activated motion system

Various aspects of visual functioning, including motion perception, change with age. Yet, there is a lack of comprehensive understanding of age-related alterations at different stages of motion processing and in each motion system. To understand the effects of aging on second-order motion processing, we investigated optomotor responses (OMR) in younger and older wild-type (AB-strain) and acetylcholinesterase (achesb55/+) mutant zebrafish. The mutant fish with decreased levels of acetylcholinesterase have been shown to have delayed age-related cognitive decline. Compared to previous results on first-order motion, we found distinct changes in OMR to second-order motion. The polarity of OMR was dependent on age, such that second-order stimulation led to mainly negative OMR in the younger group while older zebrafish had positive responses. Hence, these findings revealed an overall aging effect on the detection of second-order motion. Moreover, neither the genotype of zebrafish nor the spatial frequency of motion significantly changed the response magnitude. Our findings support the view that age-related changes in motion detection depend on the activated motion system.

Pathway and directional specificity of Hebbian plasticity in the cortical visual motion processing network

Cortico-cortical paired associative stimulation (ccPAS), which repeatedly pairs single-pulse transcranial magnetic stimulation (TMS) over two distant brain regions, is thought to modulate synaptic plasticity. We explored its spatial selectivity (pathway and direction specificity) and its nature (oscillatory signature and perceptual consequences) when applied along the ascending (Forward) and descending (Backward) motion discrimination pathway. We found unspecific connectivity increases in bottom-up inputs in the low gamma band, probably reflecting visual task exposure. A clear distinction in information transfer occurred in the re-entrant alpha signals, which were only modulated by Backward-ccPAS, and predictive of visual improvements in healthy participants. These results suggest a causal involvement of the re-entrant MT-to-V1 low-frequency inputs in motion discrimination and integration in healthy participants. Modulating re-entrant input activity could provide single-subject prediction scenarios for visual recovery. Visual recovery might indeed partly rely on these residual inputs projecting to spared V1 neurons.

Using Lean Six Sigma Methodology to Improve Resident Engagement

An engagement survey was administered in 2018 to all physicians at our institution, including residents and fellows. The results showed very low engagement scores among trainees, which focused the attention of hospital administration. In response, the Process Improvement Office (PIO) was tasked by administration to collect information about residents' concerns. A Lean Six Sigma performance improvement technique, the “waste walk,” was chosen. Lean Six Sigma is a management technique originally developed in the manufacturing sector, but now frequently used in health care settings. Lean methodology identifies specified wastes that lead to inefficiency in production, and Six Sigma methodology aims to decrease error.1,2 A waste walk is a structured visit to the workplace (the hospital, in this case) to identify 8 Lean waste types (defects, overproduction, waiting, non-utilized talent, transportation, inventory, motion, and extra processing), in order to prioritize improvement opportunities.The PIO conducted a series of waste walks to cover areas of the hospital where inefficiencies were expected or where it was suspected that waste would impact patient care. Specific programs with large hospital-based services were included, with residents selected to be included in the observations by their program directors and chief residents. Evening and overnight shifts were included in the sampling. Observations were conducted by staff from the PIO and included Lean Six Sigma Green Belts (intermediate) and Black Belts (management). Observers shadowed the resident for all clinical activities during their shift, including their interactions with patients and other staff. Observers made note of all Lean wastes noted. Over a 1-month period, 23 residents covering 20 different services and representing 16 training programs were observed, constituting 183 hours of shadowing by PIO staff. The observations were collated and categorized to the 8 Lean waste types. All trainees were then able to vote on the issues that were of greatest importance to them.Opportunities identified included issues with communication, availability of equipment, admission process for transfer patients, residents performing duties outside their scope, (eg, cleaning equipment, making appointments), and resident staffing issues. Most residents identified procedure scheduling and transfer of patients as major issues to be addressed. Tangible results of the process included improvements in information availability in the electronic medical record for outside transfers, allocation of resources to improve a resident work room, and establishment of a working group to improve handoffs. In the 2 years following the intervention, there were 12 resident-run quality improvement projects concerning communication. Education vs service scores in the Accreditation Council for Graduate Medical Education Resident/Fellow Survey improved from the 72nd percentile in 2019 to the 93rd percentile in 2020. Resident engagement scores in the 2 years following improved to a score of 4.08 out of 5. While the sources of these improvements were multifactorial, the waste walk was a tangible demonstration to the residents of the institution's commitment to them and its interest in their voices. The walks also educated the administration in the day-to-day systemic obstacles residents face in providing care.The authors acknowledge the assistance of the staff of the Process Improvement Office of Cooper Health System.

Abnormal functional connectivity density involvement in freezing of gait and its application for subtyping Parkinson's disease.

The pathophysiological mechanisms at work in Parkinson's disease (PD) patients with freezing of gait (FOG) remain poorly understood. Functional connectivity density (FCD) could provide an unbiased way to analyse connectivity across the brain. In this study, a total of 23 PD patients with FOG (PD FOG + patients), 26 PD patients without FOG (PD FOG- patients), and 22 healthy controls (HCs) were recruited, and their resting-state functional magnetic resonance imaging (rs-fMRI) images were collected. FCD mapping was first performed to identify differences between groups. Pearson correlation analysis was used to explore relationships between FCD values and the severity of FOG. Then, a machine learning model was employed to classify each pair of groups. PD FOG + patients showed significantly increased short-range FCD in the precuneus, cingulate gyrus, and fusiform gyrus and decreased long-range FCD in the frontal gyrus, temporal gyrus, and cingulate gyrus. Short-range FCD values in the middle temporal gyrus and inferior temporal gyrus were positively correlated with FOG questionnaire (FOGQ) scores, and long-range FCD values in the middle frontal gyrus were negatively correlated with FOGQ scores. Using FCD in abnormal regions as input, a support vector machine (SVM) classifier can achieve classification with good performance. The mean accuracy values were 0.895 (PD FOG + vs. HC), 0.966 (PD FOG- vs. HC), and 0.897 (PD FOG + vs. PD FOG-). This study demonstrates that PD FOG + patients showed altered short- and long-range FCD in several brain regions involved in action planning and control, motion processing, emotion, cognition, and object recognition.

Pathway and directional specificity of Hebbian plasticity in the cortical visual motion processing network

Pathway and directional specificity of Hebbian plasticity in the cortical visual motion processing network

Motion Processing and Categorical Decisions in Medial Superior Temporal and Lateral Intraparietal Areas.

Neurons in different brain regions code information for various types of decisions. Decision-making tasks based on the direction of moving dots have been used extensively to research how different brain regions process information during perceptual decisions. For example, neurons in the middle

The Influence of Lean Principles on USTP Electro-Mechanical Technology Department Waste Management and Sustainability Efforts: Case Study

This study aims to assess waste in the Electro-mechanical Department of the University of Science and Technology of Southern Philippines (USTP) based on lean principles and their impact on sustainability efforts. The study uses a case study approach, categorizing waste into eight categories and creating a risk ranking using the FMEA technique. Data collection for the risk ranking was not possible due to scheduling constraints. The literature review discusses the implementation of lean principles in higher education institutions (HEIs), waste modes in HEIs, and the potential benefits and challenges of implementing lean principles in HEIs. The study findings indicate that waste modes such as defects, overproduction, waiting, non-utilized talent, extra transportation, excess inventory, extra motion, and extra processing exist in the USTP Electro-mechanical Department. The implementation of lean principles has the potential to reduce these waste modes and improve the overall sustainability of the department. However, successful implementation requires collaboration among multiple stakeholders and adequate resources. Further research is needed to identify best practices for implementing lean principles in HEIs.

Optoelectronic graded neurons for bioinspired in-sensor motion perception.

Motion processing has proven to be a computational challenge and demands considerable computational resources. Contrast this with the fact that flying insects can agilely perceive real-world motion with their tiny vision system. Here we show that phototransistor arrays can directly perceive different types of motion at sensory terminals, emulating the non-spiking graded neurons of insect vision systems. The charge dynamics of the shallow trapping centres in MoS2 phototransistors mimic the characteristics of graded neurons, showing an information transmission rate of 1,200 bit s-1 and effectively encoding temporal light information. We used a 20 × 20 photosensor array to detect trajectories in the visual field, allowing the efficient perception of the direction and vision saliency of moving objects and achieving 99.2% recognition accuracy with a four-layer neural network. By modulating the charge dynamics of the shallow trapping centres of MoS2, the sensor array can recognize motion with a temporal resolution ranging from 101 to 106 ms.

Neurotypicals with higher autistic traits have delayed visual processing of an approaching life-sized avatar's gait: an event-related potentials study.

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, which is reportedly related to difficulties in the visual processing of human motion, such as biological motion and gestures. Moreover, neurotypical (here, we mention it as individuals without a diagnosis) adults with autistic traits are clumsier than those without autistic traits when passing by others. It is still unclear whether the clumsiness derived from atypical visual processing of another's approaching gait motion. We aim to address this question by investigating the association between autistic traits in neurotypical adults and the visual processing of an approaching life-sized avatar's gait. We clarified a typical visual motion processing and autistic traits in daily life in 26 neurotypical adults by analyzing the subthreshold autism trait questionnaire (SATQ) score, a 24-item self-report scale of ASD, and event-related potentials (ERPs) in response to walking motion of a passing avatar. Videos of walking life-sized virtual avatars approaching and retreating were presented as visual stimuli. The association between the participants' SATQ scores and the latencies and amplitudes of the ERPs was examined. ERP components (N170 and P200) components were identified at T5 and T6 electrodes. Participants reporting higher SATQ scores had longer latencies of P200 at T6 and lower amplitudes of P200 at T5 and T6 electrodes for the approaching avatar than those reporting lower SATQ scores. These findings indicate that adults with autistic traits have delayed and less sensitive visual processing of the approaching avatar. It suggests that while passing another person, these individuals have atypical visual processing of their approach. This study may contribute to elucidating autistic traits from the perspective of visual processing in an environment simulating daily life.

Dynamic machine vision with retinomorphic photomemristor-reservoir computing

Dynamic machine vision requires recognizing the past and predicting the future of a moving object based on present vision. Current machine vision systems accomplish this by processing numerous image frames or using complex algorithms. Here, we report motion recognition and prediction in recurrent photomemristor networks. In our system, a retinomorphic photomemristor array, working as dynamic vision reservoir, embeds past motion frames as hidden states into the present frame through inherent dynamic memory. The informative present frame facilitates accurate recognition of past and prediction of future motions with machine learning algorithms. This in-sensor motion processing capability eliminates redundant data flows and promotes real-time perception of moving objects for dynamic machine vision.

Development of BOLD Response to Motion in Human Infants.

Behavioral studies suggest that motion perception is rudimentary at birth and matures steadily over the first few years. We demonstrated previously that the major cortical associative areas serving motion processing, like middle temporal complex (MT+), visual cortex area 6 (V6), and PIVC in adults, show selective responses to coherent flow in 8-week-old infants. Here, we study the BOLD response to the same motion stimuli in 5-week-old infants (four females and four males) and compare the maturation between these two ages. The results show that MT+ and PIVC areas show a similar motion response at 5 and 8 weeks, whereas response in the V6 shows a reduced BOLD response to motion at 5 weeks, and cuneus associative areas are not identifiable at this young age. In infants and in adults, primary visual cortex (V1) does not show a selectivity for coherent motion but shows very fast development between 5 and 8 weeks of age in response to the appearance of motion stimuli. Resting-state correlations demonstrate adult-like functional connectivity between the motion-selective associative areas but not between primary cortex and temporo-occipital and posterior-insular cortices. The results are consistent with a differential developmental trajectory of motion area respect to other occipital regions, probably reflecting also a different development trajectory of the central and peripheral visual field.SIGNIFICANCE STATEMENT How the cortical visual areas attain the specialization that we observed in human adults in the first few months of life is unknown. However, this knowledge is crucial to understanding the consequence of perinatal brain damage and its outcome. Here, we show that motion selective areas are already functioning well in 5-week-old infants with greater responses for detecting coherent motion over random motion, suggesting that very little experience is needed to attain motion selectivity.

Motion and form coherence processing in individuals with cerebral visual impairment.

Using a visual psychophysical paradigm, we sought to assess motion and form coherence thresholds as indices of dorsal and ventral visual stream processing respectively, in individuals with cerebral visual impairment (CVI). We also explored potential associations between psychophysical assessments and brain lesion severity in CVI. Twenty individuals previously diagnosed with CVI (mean age = 17 years 11 months [SD 5 years 10 months]; mean Verbal IQ = 86.42 [SD 35.85]) and 30 individuals with neurotypical development (mean age = 20 years 1 month [SD 3 years 8 months]; mean Verbal IQ = 110.05 [SD 19.34]) participated in the study. In this two-group comparison, cross-sectional study design, global motion, and form pattern coherence thresholds were assessed using a computerized, generalizable, self-administrable, and response-adaptive psychophysical paradigm called FInD (Foraging Interactive D-prime). Consistent with dorsal stream dysfunction, mean global motion (but not form) coherence thresholds were significantly higher in individuals with CVI compared to controls. No statistically significant association was found between coherence thresholds and lesion severity. These results suggest that the objective assessment of motion and form coherence threshold sensitivities using this psychophysical paradigm may be useful in helping to characterize perceptual deficits and the complex clinical profile of CVI. In participants with cerebral visual impairment (CVI), motion (but not form) coherence thresholds were significantly higher compared to controls. These psychophysical results support the notion of dorsal stream dysfunction in CVI.

The discrimination of expressions in facial movements by infants: A study with point-light displays

Perceiving facial expressions is an essential ability for infants. Although previous studies indicated that infants could perceive emotion from expressive facial movements, the developmental change of this ability remains largely unknown. To exclusively examine infants’ processing of facial movements, we used point-light displays (PLDs) to present emotionally expressive facial movements. Specifically, we used a habituation and visual paired comparison (VPC) paradigm to investigate whether 3-, 6-, and 9-month-olds could discriminate between happy and fear PLDs after being habituated with a happy PLD (happy-habituation condition) or a fear PLD (fear-habituation condition). The 3-month-olds discriminated between the happy and fear PLDs in both the happy- and fear-habituation conditions. The 6- and 9-month-olds showed discrimination only in the happy-habituation condition but not in the fear-habituation condition. These results indicated a developmental change in processing expressive facial movements. Younger infants tended to process low-level motion signals regardless of the depicted emotions, and older infants tended to process expressions, which emerged in familiar facial expressions (e.g., happy). Additional analyses of individual difference and eye movement patterns supported this conclusion. In Experiment 2, we concluded that the findings of Experiment 1 were not due to a spontaneous preference for fear PLDs. Using inverted PLDs, Experiment 3 further suggested that 3-month-olds have already perceived PLDs as face-like stimuli.

Global motion processing in infants’ visual cortex and the emergence of autism

Autism is a heritable and common neurodevelopmental condition, with behavioural symptoms typically emerging around age 2 to 3 years. Differences in basic perceptual processes have been documented in autistic children and adults. Specifically, data from many experiments suggest links between autism and alterations in global visual motion processing (i.e., when individual motion information is integrated to perceive an overall coherent pattern). Yet, no study has investigated whether a distinctive organization of global motion processing precede the emergence of autistic symptoms in early childhood. Here, using a validated infant electroencephalography (EEG) experimental paradigm, we first establish the normative activation profiles for global form, global motion, local form, and local motion in the visual cortex based on data from two samples of 5-month-old infants (total n = 473). Further, in a sample of 5-month-olds at elevated likelihood of autism (n = 52), we show that a different topographical organization of global motion processing is associated with autistic symptoms in toddlerhood. These findings advance the understanding of neural organization of infants’ basic visual processing, and its role in the development of autism.

Alternative brain connectivity underscores age-related differences in the processing of interactive biological motion.

Rapidly recognizing and understanding others' social interactions is an important ability that relies on deciphering multiple sources of information; for example, perceiving body information and inferring others' intentions. Despite recent advances in characterizing the brain basis of this ability in adults, its developmental underpinnings are virtually unknown. Here, we used fMRI to investigate which sources of social information support superior temporal sulcus (STS) responses to interactive biological motion (i.e. 2 interacting point-light human figures) at different developmental intervals in human participants (of either sex): Children show supportive functional connectivity with key nodes of the mentalizing network, while adults show stronger reliance on regions associated with body- and dynamic social interaction/biological motion processing. We suggest that adults employ efficient action-intention understanding via body and biological motion information, while children show a stronger reliance on hidden mental-state inferences as a potential means of learning to better understand others' interactive behavior.SIGNIFICANCE STATEMENT:Recognizing others' interactive behavior is a critical human skill that depends on different sources of social information (e.g. observable body-action information, inferring others' hidden mental-states etc.). Understanding the brain-basis of this ability, and characterizing how it emerges across development are important goals in social neuroscience. Here, we used fMRI to investigate which sources of social information support interactive biological motion processing in children (6-12 years) and adults. These results reveal a striking developmental difference in terms of how wider-brain connectivity shapes functional responses to interactive biological motion that suggests a reliance on distinct neuro-cognitive strategies in service of interaction understanding (i.e. children and adults show a greater reliance on explicit and implicit intentional inference, respectively).

Differing postural control patterns in individuals with bilateral and unilateral hearing loss

ObjectivesHearing loss (HL) is associated with imbalance and increased fall risk. The mechanism underlying this relationship and differences across types of hearing loss remains unclear. Head mounted displays (HMD) can shed light on postural control mechanisms via an analysis of head sway. PurposeThe purpose of this study was to evaluate head sway in response to sensory perturbations in individuals with bilateral (BHL) or unilateral hearing loss (UHL) and compare them to controls. Materials and methodsWe recruited 36 controls, 23 individuals with UHL and 14 with BHL. An HMD (HTC Vive) measured head sway while participants stood on the floor, hips-width apart. Stimuli included two levels of visuals and sound. Root Mean Square Velocity (RMSV) and Power Spectral Density (PSD) were used to quantify head sway. ResultsAdjusting for age, individuals with BHL had significantly higher anterior-posterior and medio-lateral RMSV than controls and individuals with UHL. Individuals with UHL demonstrated significantly lower response to visual perturbations in RMSV AP and in all 3 frequency segments of PSD compared to controls. Individuals with UHL showed significantly lower movements at high frequencies compared to controls. Sounds or severity of HL did not impact head sway. ConclusionsIndividuals with BHL demonstrated increased sway with visual perturbations and should be clinically assessed for balance performance and fall risk. Individuals with UHL exhibited reduced responses to visual stimuli compared with controls, which may reflect conscious movement processing. Additional studies are needed to further understand the mechanistic relationship between hearing loss and imbalance.

The Role of Objecthood and Animacy in Apparent Movement Processing.

Although the ability to detect the actions of other living beings is key for adaptive social behavior, it is still unclear if biological motion perception is specific to human stimuli. Biological motion perception involves both bottom-up processing of movement kinematics ('motion pathway) and top-down reconstruction of movement from changes in body posture ('form pathway'). Previous research using point-light displays has shown that processing in the motion pathway depends on the presence of a well-defined, recognizable shape (objecthood) but not necessarily on whether that shape depicts a living being (animacy). Here, we focused on the form pathway. Specifically, we combined EEG frequency tagging with apparent motion to study how objecthood and animacy influence posture processing and the integration of postures into movements. By measuring brain responses to repeating sequences of well-defined or pixelated images (objecthood), depicting human or corkscrew agents (animacy), performing either fluent or non-fluent movements (movement fluency), we found that movement processing was sensitive to objecthood but not animacy. In contrast, posture processing was sensitive to both. Together, these results indicate that reconstructing biological movement from apparent motion sequences requires a well-defined, but not necessarily an animate shape. Instead, stimulus animacy appears to be relevant only for posture processing.