Prevalence Of Chronic Rhinosinusitis Research Articles

Prevalence of Chronic Rhinosinusitis with Nasal Polyps in Catalonia (Spain): a retrospective, large-scale population-based study.

Studies on the prevalence of chronic rhinosinusitis (CRS) with nasal polyps (NP) in general-based populations are scarce in Europe and worldwide. We performed a retrospective population-based observational cohort study of 30,189 adult patients diagnosed with NP in Catalonia (Spain). Adult individuals (≤18 years old) with a diagnosis of NP established by medical records at different health care levels (primary, hospital, and emergency) from the Catalan Health System (CHS) were included. Socio-demographic characteristics, prevalence, overall and by age and gender, disease severity, multi-morbidities, and biomarkers of type-2 inflammation were evaluated, together with appropriate medical treatment (AMT) and Endoscopic Sinus Surgery (ESS). In general population and severity sub-populations, the overall diagnosed NP prevalence was 0.49% and higher for males than females (0.60% vs 0.39%, p less than 0.0016). The prevalence for the severe NP population was 0.12%. The NP prevalence increased with age, the highest being at ≤60 years old for both gender and severity groups. Asthma (40.1%), acute rhinosinusitis (41.1%), and allergic rhinitis (32.1%) were among the most frequent comorbid respiratory diseases. ESS was performed in 15.4% of NP patients. Type 2 inflammation was present in 83.8% of the NP population and was more frequent in severe than non-severe (87.1% vs 82.7%, p less than 0.0001) patients and in those with respiratory multi-morbidities (91%). This is the first large-scale population-based NP epidemiology study conducted in Spain, including severity based on undergoing medical and surgical treatment and type 2 inflammation. Although the prevalence data are lower than in previous European studies, the large NP cohort studied represents an essential strength of the results.

Increased Prevalence of Eosinophilic Esophagitis in Patients With Chronic Rhinosinusitis.

Chronic rhinosinusitis (CRS) and eosinophilic esophagitis (EoE) are immune-mediated inflammatory conditions that share common histopathologic features. Once considered two separate pathologies, preliminary data has suggested that a higher prevalence of EoE may exist in patients with CRS. We aimed to expand the base of evidence across geographic regions and investigate the association between EoE and CRS, including CRS with nasal polyposis (CRSwNP). Quantitative data detailing the prevalence of CRS, CRSwNP, and EoE were pooled from 6 large academic institutions spread across the United States using Epic electronic medical record system. One-way analysis of variance was then used to analyze the data. The mean prevalence of EoE in our general population sample of over 26 million individual records was 0.058% (range, 0.013%-0.103%). The mean prevalence of EoE in our sub-populations of individual with diagnoses of CRS and CRSwNP was 0.43% (F(1,12) = [8.194], P = .01) and 0.84% (F(1,12) = [23.61], P < .01) respectively. This study reveals an 8-fold greater prevalence of concurrent EoE in patients with CRS. Importantly, this is the first study to describe the association of EoE and the CRSwNP subtype, and we demonstrate a 14-fold greater prevalence of EoE in patients with CRSwNP.

Prevalence of chronic rhinosinusitis and its relating factors in patients with bronchiectasis: findings from KMBARC registry.

Background/AimsPatients with bronchiectasis often present with respiratory symptoms caused by chronic rhinosinusitis (CRS). However, studies on the prevalence of CRS and its relationship with bronchiectasis are limited.MethodsThe baseline characteristics of patients with bronchiectasis recruited from the Korean Multicenter Bronchiectasis Audit and Research Collaboration were analyzed. CRS diagnosis was determined by a physician, on the basis of medical records, upper airway symptoms, and/or radiologic abnormalities. Questionnaires for quality of life, fatigue, and depression were administered when patients were stable for a minimum of 4 weeks after the bronchiectasis exacerbation.ResultsThe prevalence of CRS was 7.1% (66/931). Patients with CRS were significantly younger than those without CRS (60.5 ± 10.7 years vs. 64.6 ± 9.3 years, p = 0.001). Idiopathic bronchiectasis was more common in patients with CRS compared to those without CRS (53.0% vs. 36.0%, p = 0.006). Lung function, inflammatory markers, exacerbations, bronchiectasis severity, and scores for quality of life, fatigue, and depression did not differ between the two groups. In a logistic regression analysis, CRS was associated with age of bronchiectasis diagnosis (odds ratio [OR], 0.96; 95% confidence interval [CI], 0.94 to 0.99; p = 0.003) and idiopathic bronchiectasis (OR, 1.95; 95% CI, 1.12 to 3.34; p = 0.018).ConclusionsThe prevalence of CRS was relatively low. CRS was not associated with the severity or clinical outcomes of bronchiectasis. Early diagnosis and idiopathic etiology were associated with CRS. Our findings reflect the low recognition of CRS in the clinical practice of bronchiectasis and highlight the need for awareness of CRS by adopting objective diagnostic criteria.

Management of Patients with Severe Asthma and Chronic Rhinosinusitis with Nasal Polyps: A Multidisciplinary Shared Approach

Chronic rhinosinusitis (CRS) is one of the most frequent comorbidities associated with asthma and it contributes to an amplified global disease burden in asthmatics. CRS prevalence is much higher in asthmatic patients compared to the general population and it is more frequently related to severe asthma, especially in presence of nasal polyps (chronic rhinosinusitis with nasal polyps, CRSwNP). Moreover, asthma exacerbation has a higher occurrence in CRSwNP. From a pathologic point of view, CRS and asthma share similar and connected mechanisms (e.g., type-2 inflammation). A multidisciplinary approach represents a crucial aspect for the optimal management of patients with concomitant asthma and CRSwNP and improvement of patient quality of life. An Italian panel of clinicians with different clinical expertise (pulmonologists, ear, nose and throat specialists, immunologists and allergy physicians) identified three different profiles of patients with coexisting asthma and nasal symptoms and discussed the specific tracks to guide a comprehensive approach to their diagnostic and therapeutic management. Currently available biological agents for the treatment of severe asthma act either on eosinophil-centered signaling network or type-2 inflammation, resulting to be effective also in CRSwNP and representing a valid option for patients with concomitant conditions.

The negative impact of chronic rhinosinusitis on the health-related quality of life among adult patients with cystic fibrosis

BackgroundWith improved survival in cystic fibrosis (CF) patients, it is crucial to evaluate the impact of chronic co-morbidities such as chronic rhinosinusitis (CRS). The objectives were 1) To determine the prevalence of CRS with a large series of CF patients 2) To evaluate the impact of CRS on the Health-Related Quality of Life (HRQoL) of CF patients and 3) To compare CRS-specific, CF-specific and general HRQoL instruments. MethodsConsecutive CF patients from the Toronto Adult Cystic Fibrosis Centre were recruited between March 2018 and January 2020. Participants completed the 22-Item Nasal Outcome Test (SNOT-22), Cystic Fibrosis Questionnaire-Revised for adolescents and adults over 14 years of age (CFQ-R), Cystic Fibrosis Quality of Life Evaluative Self-administered Test (CF-QUEST) and the 36-Item Short Form Survey (SF-36). HRQoL scores were correlated using Spearman's correlation coefficients. ResultsOut of 195 patients eligible for analysis, the prevalence of CRS with positive endoscopic findings was 42.6% (95% confidence interval: 35.5–49.8%). CRS patients reported significantly lower HRQoL with higher SNOT-22 scores and lower scores in the respiratory domain of CFQ-R and physical health domains of CF-QUEST and SF-36. The physical (ρ= −0.63) and mental (ρ= −0.66) domains of SF-36 and CF-QUEST (ρ= −0.76) had a strong correlation with SNOT-22. Higher scores of SNOT-22 nasal subdomains correlated with lower scores of SF-36, CFQ-R and CF-QUEST. ConclusionCRS is a prevalent co-morbidity of CF patients, which significantly reduces HRQoL. SNOT-22, CFQ-R, CF-QUEST and SF-36 were strongly correlated. Severity of sinonasal symptoms have a strong correlation with HRQoL in CF patients.

Treatment of chronic rhinosinusitis exacerbations

Introduction. The prevalence of chronic rhinosinusitis, an increase in the resistance of pathogenic microorganisms, growing numbers of patients with allergic reactions to antibiotics necessitates the use of topical antibacterial therapy or the nasal cavity and paranasal sinuses, which are accessible for local remedies.Aim. Efficacy and tolerability of topical antibacterial drug hydroxymethylquinoxalindioxide in the treatment of chronic rhinosinusitis exacerbation has been investigated in our study.Materials and methods. An open non-invasive observational study of efficacy and tolerability of irrigation therapy with hydroxymethylquinoxalindioxide in 50 adult patients with exacerbation of chronic rhinosinusitis has been conducted at the Department of Otorhinolaryngology, Pavlov State Medical University (Saint Petersburg). The patients were randomized into 2 groups. In the first group, patients were treated with 40 ml of 0.25% hydroxymethylquinoxalindioxide solution nasal irrigation b.i.d. for 7 days, in the second – the same amount of normal saline was used. Duration and severity of symptoms, dynamics of nasal endoscopic picture, and the results of bacteriological study were evaluated before and after the treatment. Safety was assessed according to the data of complete blood cell count, mucociliary transport time and the incidence of adverse events.Results and discussion. In the hydroxymethylquinoxalindioxide group, there was a statistically significant improvement in the mucociliary transport time by the end of treatment from 19.1 ± 5.08 minutes to 15.2 ± 1.2 minutes (p = 0.002) compared to the normal saline group. According to the results of bacteriological study, eradication of the pathogen in the hydroxymethylquinoxalindioxide group was achieved in 85% (n = 21), comparing to only 17% (n = 4) of cases in the control group.Conclusion. Irrigation therapy with 0.25% hydroxymethylquinoxaline dioxide is more effective than saline flush solution. The drug can be recommended for irrigation therapy in adults with chronic rhinosinusitis exacerbation.

Association between Concentration of Air Pollutants and Prevalence of Inflammatory Sinonasal Diseases: A Nationwide Cross-sectional Study

Air pollution is a serious health concern and affects inflammatory sinonasal diseases such as allergic rhinitis (AR) and chronic rhinosinusitis (CRS). Clarifying the relationship between air pollutants and upper respiratory diseases could help the patients. To evaluate the association between the concentration of air pollutants and the prevalence of AR and CRS among South Koreans. In this cross-sectional study, nationwide data were reviewed for participants of the Korean National Health and Nutrition Examination Survey (KNHANES) 2008 to 2012. Participants were surveyed with health questionnaires, examined with endoscopies by otolaryngologists, and tested with serum immunoglobulin E levels. The concentrations of sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), and particulate matter with aerodynamic diameters ≤10 µm (PM10) were measured in 16 areas of South Korea. Air pollutant concentrations of geographic districts were matched to each participant's residence. Logistic regression analysis was performed. Among 27 863 eligible adults, 3359 and 1606 participants had AR or CRS, respectively. In multivariable logistic regression analysis for AR, PM10 showed statistically significant results (odds ratio [OR] = 1.145, 95% confidence interval [CI] = 1.042-1.258). No air pollutants showed statistically significant differences in the prevalence of CRS. In AR, PM10 (OR = 1.458, 95% CI = 1.201-1.770) was associated with endoscopic findings of watery rhinorrhea, whereas SO2 (OR = 1.202, 95% CI = 1.100-1.313) was associated with pale mucosa. The prevalence of AR was significantly associated with PM10 concentration. In patients with AR, endoscopic findings of watery rhinorrhea were associated with PM10. However, CRS was not associated with the air pollutant concentrations. Lower concentration of PM10 might help managing the clinical symptoms in patients of AR.

Occupational and environmental exposures, the association with chronic sinusitis.

Objectives:To find the association between environmental and occupational exposures and chronic rhinosinusitis (CRS) development.Methods:The Preferred Reporting Items Of Systematic Reviews Guidelines were used when a systematic literature review was conducted to find all published cases of CRS by searching PubMed database and Google Scholar. Published articles between 1989 and 2021 that reported chronic and occupational rhinosinusitis were included. However, articles that reported allergic rhinitis or upper airway diseases and non-English articles were excluded from this study.Results:A total of 97 articles were extracted initially, and 15 articles were reviewed after excluding 82 articles that did not match our inclusion criteria. Most studies linked CRS development to smoke exposure (n=9734), followed by living in rural areas as farms (n=5504). Exposure to pesticides (n=4248) contributed to a higher prevalence of CRS. Blue-collar occupations, such as fire fighters, farmers, and fishermen were significantly related to CRS development in a total of 5260 patients. Chronic rhinosinusitis mainly affected more men (n=8912) than women (n=8076).Conclusion:We found that smoking was the most aggravating environmental factor. Chronic rhinosinusitis symptoms’ severity increased with direct contact with allergens. Thus, the greatest proportion of patients with CRS was those with blue-collar occupations, such as firefighters, farmers, and fishermen.

Epidemiology of Chronic Rhinosinusitis: Prevalence and Risk Factors

Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care: aiding patient identification and establishing accurate diagnosis as well as informing treatment decisions. The objective of this review is to summarize the current evidence on the epidemiology of CRS, with a focus on prevalence and risk factors. Although the presence of either symptoms or objective findings alone have yielded CRS prevalence estimates of over 10%, the presence of both-consistent with guideline-based diagnostic criteria for CRS-has suggested that the true prevalence of CRS is consistently less than 5%, with approximately one-third of patients with CRS having nasal polyps, in epidemiologic studies from around the world. In comparison, the prevalence of CRS endotypes-pathophysiologic subclassification of CRS most commonly as related to type 2 or non-type 2 inflammation-has been found to vary significantly by region. The epidemiology of CRS is modified and ultimately determined by risk factors: genetic/hereditary, demographic, environmental, and imparted by predictive pre-/comorbid disease. The understanding of these epidemiologic relationships may help the provider to optimally identify and understand each individual's CRS disease process, thereby improving both diagnosis and treatment.

Prevalence, quality of life and risk factors of chronic rhinosinusitis in adults in Kingdom of Saudi Arabia 2021

Background: Chronic rhinosinusitis is one of the most prevalent chronic diseases worldwide, affecting all age groups. It is a condition leading to a significant decrease in the quality of life of patients, and requires a specific treatment approach. This study aims to assess the prevalence, quality of life and risk factors of chronic rhinosinusitis in order to develop and promote public health, wellbeing and awareness. Methodology: This is a cross-sectional study which was conducted in the Kingdom of Saudi Arabia, from August to October 2021. We collected the data using a validated, self-administrated online sinonasal outcome test (SNOT-22) questionnaire in Arabic. The questionnaire was distributed through social media and aimed to assess the prevalence and risk factors of chronic rhinosinusitis in the Kingdom of Saudi Arabia in 2021. Results: In the current study, we collected data from 4963 individuals in Saudi Arabia who responded to to our questionnaire. Participants had a mean age of 31.99 (SD=11.59) years old, 62.0% were females and 92.9% were Saudis. Among the total sample, the prevalence of chronic rhinosinusitis (CRS) was 22.5%. The prevalence of CRS was significantly lower in patients aged between 18-29 years old (19.4%) compared with the 30-49 age group (27.1%) and 50-69 age group (23.2%) (P=0.000). Moreover, we found that the prevalence of CRS was significantly higher among females (24.0% vs 20.2%, P=0.002) and among Saudis compared to non-Saudis (22.9% vs 17.6%, P=0.022). Furthermore, there was a significant reduction in the quality of life among patients with CRS where the mean score of SNOT-22 was 44.04 (SD=25.38) compared with 26.82 (SD=26.35) in non-patients. Conclusion: The current study revealed a high prevalence of CRS among individuals in Saudi Arabia especially among older females, those with chronic conditions and those who had been exposed to different risk factors such as smoking. Moreover, CRS was found to have a significantly negative impact on the quality of life for those participants diagnosed with the condition. Keywords: Quality of life, chronic sinusitis, adults, Saudi Arabia

Оценка распространенности хронического риносинусита

Objective. To summarize data on the epidemiology of chronic rhinosinusitis (CRS) with an emphasis on prevalence and risk factors. Materials and methods. The analysis of English- and Russian-language publications using databases: PubMed, Russian Science Citation Index, Springer, Scopus, Scientific Research, Crossref, eLibrary. The search depth is 10 years (2012–2022). The paper presents data from original epidemiological studies, reflects differences in estimates of the prevalence of the disease depending on the research method, sample characteristics, predisposing environmental conditions. Results. The use of symptomatology and objective diagnostic criteria makes it possible to identify the prevalence of CRS in more than 10% of the population. When using both methods, the true prevalence of CRS is about 5%. Differences in the prevalence of CRS associated with concomitant living conditions and the general condition of patients indicate the presence of risk factors, such as modifiable: smoking, air pollution, socioeconomic, comorbid diseases, as well as unmodified: hereditary, demographic (gender, race, age). Conclusion. During the follow-up period, along with the introduction of new treatment methods, the prevalence of CRS in Russia and the world has been maintained, which requires improving the organizational and methodological approach to the prevention, diagnosis, and treatment of this disease. The expansion of data on the epidemiological patterns of CRS makes it possible to optimally identify the disease process for each patient, thereby contributing to an increase in the effectiveness of treatment at the general social level.

Association between the use of electronic cigarettes and the prevalence of chronic rhinosinusitis and allergic rhinitis: a nationwide cross-sectional study

Background: Whether the use of electronic cigarettes (ECs) is associated with upper airway diseases, including chronic rhinosinusitis (CRS) and allergic rhinitis (AR), remains unclear. Methods: We analyzed data from the nationwide cross-sectional surveys: the Korea National Health and Nutrition Examination Survey VI (2013–2015), VII (2016–2018), and VIII (2019). Logistic regression analysis was performed to assess the association between EC use and CRS or AR. Results: Among a total of 38,413 participants, 6.4% were former EC users and 2.5% were current EC users. Former EC users and current EC showed a significantly increased OR for CRS or AR compared with never EC users. In the subgroup analysis, the “current CC (conventional cigarette)-current EC” and the “current CC-formal EC” group had a significantly higher OR for CRS or AR than the “current CC-never EC” group. In addition, former CC smokers who currently use ECs showed a significantly higher OR for AR than former CC smokers without EC use. Conclusions: EC use is significantly associated with a high prevalence of CRS and AR in the adult population. These results indicate that the use of ECs may increase the risk of upper airway disease.

Association between diabetes mellitus and chronic rhinosinusitis with nasal polyps: A population-based cross-sectional study.

To investigate the association between physician-diagnosed diabetes mellitus (DM) and chronic rhinosinusitis (CRS) phenotypes in a national population-based study. Retrospective cross-sectional study. Population-based survey data were collected by the Korean National Health and Nutrition Survey between January 2008 and December 2012. A total of 34670 participants aged over 19years were enrolled in the Korea National Health and Nutrition Examination Surveys from 2008 to 2012. The relationship of CRS prevalence, with and without nasal polyps, with physician-diagnosed DM and non-DM were assessed. Differences in sinonasal symptoms between patients with and without DM were analysed in this cross-sectional study. A significant association was observed between DM and CRS with nasal polyps after adjustment for multiple variables. No substantial association was observed between DM and CRS without nasal polyps. Among patients with CRS, olfactory dysfunction for >3months was significantly more frequent in the DM group than in the non-DM group. We demonstrated significant associations between DM and CRS with nasal polyps and olfactory dysfunction among patients with CRS in a large national clinical cohort study. The direct mechanism of the association between DM and CRS with nasal polyps should be further investigated to clarify the pathogenesis of CRS with nasal polyps.

Association between air pollution and chronic rhinosinusitis: a nested case-control study using meteorological data and national health screening cohort data.

Inconsistent results about the effect of air pollution on chronic rhinosinusitis (CRS) have been reported. This study aimed to evaluate the impact of meteorological conditions/air pollution on the prevalence of CRS in adult Koreans. The data from the Korean National Health Insurance Service-Health Screening Cohort from 2002 through 2015 were used. A CRS group (defined as ICD-10 codes J32, n=6159) was matched with a control group (n=24,636) in 1:4 ratios by age, sex, income, and region of residence. The meteorological conditions and air pollution data included the daily mean, highest, and lowest temperature (°C), daily temperature range (°C), relative humidity (%), ambient atmospheric pressure (hPa), sunshine duration (hr), and the rainfall (mm), SO2 (ppm), NO2 (ppm), O3 (ppm), CO (ppm), and PM10 (μg/m3) levels before the CRS diagnosis. Crude and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for CRS were analyzed using logistic regression analyses. When the NO2 level increased by 0.1 ppm, the odds for CRS increased 5.40 times, and when the CO level increased by 1 ppm and PM10 increased by 10 μg/m3, the odds for CRS decreased 0.75 times and 0.93 times, respectively. Other meteorological conditions, such as the mean/highest/lowest temperature, temperature range, rainfall and other air pollution, such as SO2 and O3, were not statistically significant. NO2 for 90 days before the index date increased the risk of CRS in all subgroups, except for the nasal polyp and older age subgroups. CRS is related to high concentrations of NO2.

Association between body composition indices and prevalence of chronic rhinosinusitis in Koreans.

Association between body composition indices and prevalence of chronic rhinosinusitis in Koreans.

Role of Environmental Air Pollution in Chronic Rhinosinusitis

Chronic rhinosinusitis (CRS) is a highly prevalent disease with large social and financial burdens. The pathophysiology is multifactorial. Environmental pollutants have been suggested to play a role in the inflammatory component of the disease process. Recent work has focused on exposure to various pollutants, primarily particulate matter (PM). Exposure to environmental pollutants leads to upregulation of inflammatory markers and ciliary dysfunction at the cellular level. Mouse models suggest a role for epithelial barrier dysfunction contributing to inflammatory changes after pollutant exposure. Clinical studies support the role of pollutants contributing to disease severity in certain populations, but the role in CRS incidence or prevalence is less clear. Research is limited by the retrospective nature of most studies. This review focuses on recent advancements in our understanding of the impact of environmental pollutants in CRS, limitations of the available data, and potential opportunities for future studies.

Prevalence and Risk Factor of Chronic Rhinosinusitis and the Impact on Quality of Life in Students of the Medical Faculty Christian University of Indonesia in 2018

Chronic Rhinosinusitis (CRS) is an inflammation of nasal mucose dan paranasal sinuses with ≥ two symptoms, one of which should be nasal blockage/ obstruction or nasal discharge (anterior/ posterior nasal drip) that happened for ≥ 12 Weeks. CRS affects 5-15% adult population in Europe and the United States of America, with a prevalence of 2-4% that doctors have diagnosed. The risk factors of CRS that quite often happened on CRS is allergic rhinitis. CRS also often happened in women. CRS also impact the patient's quality of life. This study aims to know the prevalence and risk factor of CRS and the impact on quality of life on 160 students of the Medical Faculty Christian University of Indonesia uses a validated questionnaire and SNOT-22 questionnaire. This study uses a descriptive method with a cross-sectional approach. The results of CRS prevalence in this study are 71 students (44,4%), with a gender distribution are 52 students (53,2%). The correlation of allergic history suspect with CRS is proven by a statistic test using chi-square with results P=0,003 (P&gt;0,05) with a majority of the distribution is allergic rhinitis are 60 students (90,1%). All respondents answered that CRS impacts their quality of life with most of the symptoms: nasal blockage/ obstruction and 36 students (57,7%).&#x0D; Keywords: Chronic Rhinosinusitis, Nasal Mucosa Inflammation, Allergic History, Allergic Rhinitis, Gender, Quality of Life.

Maxillary Rhinosinusitis Profil In General Hospital Of Haji Surabaya On January-December 2017

Chronic rhinosinusitis in various countries in the world and Indonesia shows an increase from time to time. At General Hospital of Haji Surabaya, the prevalence of chronic rhinosinusitis has increased from 10.13% in 2016 to 10.26% in 2017. Various factors are thought to cause chronic rhinosinusitis. Chronic rhinosinusitis can interfere with the quality of life and lead to serious complications if left untreated. To determine the profile of chronic rhinosinusitis in General Hospital of Haji Surabaya for January-December 2017 Period. Analytic observational with cross-sectional study approach. Used the total sampling method. Based on patients diagnosed with chronic rhinosinusitis with complete medical record data. The sample in this study were 132 patients. Most chronic rhinosinusitis patients were aged 36-45 years as many as 26 patients (19.69%) and the least number of patients was more than 65 years old as many as 6 patients, women (67.40%) and 43 patients in men (32, 60%). Symptoms of nasal congestion in 79 patients (59.84%), cough as many as 25 patients (18.93%), septal deviation as many as 51 patients (38.63%) and at least 4 patients (3.03%) of nasal polyps. Most rhinosinusitis patients in this study were aged 36-45 years, women with symptoms of nasal congestion and septal deviation as the most comorbidities.

Multidisciplinary consensus on a stepwise treatment algorithm for management of chronic rhinosinusitis with nasal polyps.

Multidisciplinary consensus on a stepwise treatment algorithm for management of chronic rhinosinusitis with nasal polyps.

ORTA ANADOLU'DA KRONİK RİNOSİNÜZİTİN BİREYSEL ÖZELLİKLER VE ÇEVRESEL FAKTÖRLERLE İLİŞKİSİ

OBJECTIVE: The aims of this study were to investigate the prevalence and distribution of sinonasal diseases in patients that underwent paranasal sinus computed tomography (CT) due to chronic rhinosinusitis (CRS) with or without nasal polyps, and to explore the association between CRS and sinonasal variations and the effect of environmental factors.MATERIAL AND METHODS: The paranasal sinus CT images and files of 1000 patients that referred to a tertiary health center in Ankara were retrospectively evaluated. The CT findings, smoking status, presence of allergies, place of residence (urban/rural), and history of functional endoscopic sinus surgery were noted.RESULTS: CRS was seen in 68% of the patients, and most common in maxillary sinuses (53%). Nasal polyps with CRS were noted in 11% of the cases. CRS was also more common among smokers (p&amp;lt;0.001). In CRS accompanied by nasal polyps, no difference was found between urban and rural residence. However, most cases of CRS with nasal polyps lived in urban areas (81.4%, p=0.006). There was no difference between allergy and CRS with and without nasal polyps or between sinonasal variations and CRS development.CONCLUSIONS: In the region investigated, the prevalence of CRS with nasal polyps was higher in the urban area (higher air pollution); however, the prevalence of CRS without nasal polyps did not change according to the place of residence. CRS was generally more common among smokers, but there was no significant difference in patients with CRS accompanied by nasal polyps. CRS was not more common in people with allergies.