The integration of the college student financial aid system and ideological and political education is an important measure to implement the fundamental task of moral education, and also the core path to enhance the educational value of the financial aid work. At present, there are some practical difficulties in the process of integration between the two, such as a lack of coordination of objectives, poor connection of content, a single and fixed state of carrier presentation, and a lack of a mechanism for guarantee. Building upon these foundations, this paper explores practical pathways through four dimensions: precise alignment of integration objectives, deepening content system coherence, innovative implementation of integration practices, and enhanced collaborative support mechanisms. These efforts aim to synchronize funding-based education with ideological-political education, ultimately empowering the cultivation of new-era talents capable of shouldering the monumental responsibility of national rejuvenation.

TRACING POLISH EMIGRATION IN BRAZIL: CAUSES AND SIGNIFICANCE OF RESEARCH ON THE BRAZILIAN POLISH-LANGUAGE PRESS The analysis of the research on Polish linguistic traces in Brazil reveals a predominance of studies focused on spoken Polish in Brazil. In contrast, Brazilian polonica, both in terms of their content and linguistic form, remain a less explored research area. The linguistic and cultural material found in over a hundred periodicals published in Polish in the late 19th and 20th centuries represents a largely unexplored source of knowledge about the history of Polish immigrants and their descendants in Brazil. Press materials can serve as a valuable resource for studying both the linguistic practices of Polish immigrants on various levels and their language ideologies and beliefs. The aim of this article is to preliminarily define the object of research along with an explanation of the rationale that prompted us to take up the subject of the Polish press in Brazil. Its overview will be preceded by a discussion of the state of research and presentation of the literature on the subject.

Evaluation of Bleeding Disorders in the Newborn.

This article explores the relevance of presenting legal content in internet publications through multimedia tools. The author analyzes how legal information can be simplified and made more accessible through the use of videos, infographics, animations, and podcasts. The paper highlights the role of interactivity and visual communication in enhancing public understanding of legal matters. Drawing on psychological and cognitive research, particularly the works of R. Mayer and E. Tufte, the article demonstrates the effectiveness of multimedia in legal communication. It also examines the current state of legal content presentation in Uzbek internet media, existing challenges, and ways to improve it. Emphasis is placed on international experience and the strategic importance of multimedia in raising legal awareness among the population of Uzbekistan.

Wide range of disorders fall into the intersection between Psychiatry and Neurology. Movement Disorders namely dystonia, chorea, tics, tremors and myoclonus often raise dilemma between coarse brain pathology and functional disorder. Faciobrachial Dystonia due to autoimmune encephalitis presents with dystonic movements of face and arm; memory impairment and psychiatric symptoms which may create uncertainty between the diagnosis of neurologic disorder and psychogenic movement disorder. This is a case of a middle-aged lady who presented in the chamber of a psychiatrist with irrelevant speech, jerky movement of right side of face and hand and forgetfulness of recent events. MMSE score at the presentation were 20. Her symptoms were not responsive to conventional anti-epileptic, anxiolytic or sedative-hypnotics. Thus, she was advised an MRI on the basis of which she was referred to a neurologist. On the basis of clinical presentation, physical and mental state examination and laboratory investigation, the lady has been diagnosed as a case of Faciobrachial Dystonia due to anti LGI 1 autoimmune encephalitis. She was given Methyl Prednisolone 1 gm daily for 5 days followed by oral methyl Prednisolone and rapid tapering within 1 month. Following high dose steroid treatment, the frequency of her dystonic movements improved robustly. Psychiatrists are often the first point of contact for the patients with movement disorder. Knowledge and skills for early diagnosis and timely referral makes the care more comprehensive for the patients. Moreover, they can collaborate with neurologists and other healthcare professionals to provide integrated, multidisciplinary care that addresses both the physical and mental health needs of the patients. J Shaheed Suhrawardy Med Coll 2023; 15(2): 44-46

Introduction: Patients in paediatric age group in a routine otorhinolaryngology outpatient department present with varied complaints of foreign body insertion. They can be sometimes simple to remove but at many instances produce tricky surgical challenges to safely remove the foreign body. The evaluation of the psychosocial behaviour of patients presenting with foreign bodies in the ear, nose, and throat aims to develop a protocol based on a scoring system for their removal. Methods: Emergency department data from September 2021 to August 2024 was analysed retrospectively. A group of 217 patients below 15years of age who presented with foreign bodies of ear, nose and throat were included for study. Their biological data, psychosocial state, type and location of foreign body, presentation, associated complication and methodology for removal and postoperative management were obtained. Results: The patients in early childhood (1-5 yrs) had maximum number of foreign bodies (131, 60.36%). The foreign bodies were mostly located in ears (57.14%), nose (19.35%), oropharynx (13.82%), oesophagus (8.75%) and bronchus (0.92%) sequentially according to numbers. Conclusion: This study highlights the prevalence and distribution of foreign bodies in paediatric patients with their psychological state, particularly in early childhood. It also proposes a novel scoring system to aid in the effective planning and management of foreign body retrieval in emergency settings.

Triple-negative breast cancer (TNBC) presents considerable obstacles because of its highly aggressive characteristics and limited availability of specific therapeutic interventions. The utilization of monoclonal antibody (mAb)-based immunotherapy is a viable approach to tackle these difficulties. This review aims to examine the present state of mAb-based immunotherapy in TNBC, focusing on the underlying mechanisms of action, clinical applications, and existing challenges. The effectiveness of mAbs in reducing tumor development, regulating immune responses, and changing the tumor microenvironment has been demonstrated in many clinical investigations. The challenges encompass several aspects such as the discovery of biomarkers, understanding resistance mechanisms, managing toxicity, considering costs, and ensuring accessibility. The future is poised to bring forth significant advancements in the field of biomedicine, particularly in the areas of new mAbs, personalized medicine, and precision immunotherapy. In conclusion, mAb-based immunotherapy has promise in revolutionizing the treatment of TNBC, hence providing a possible avenue for enhanced patient outcomes and quality of life.

Photocatalytic activity of zinc oxide nanorods incorporated graphitic carbon nitride catalyst

Serum biomarkers as prognostic markers for Alzheimer's disease in a clinical setting.

This article delves into the current state and inherent deficiencies of corporate financial statement presentation, thoroughly examining issues pertaining to information disclosure, format standardization, comparability, and user orientation. Through a comprehensive analysis of actual cases and literature, the piece highlights the shortcomings in the transparency and decision-utility of existing financial statement presentation. In response to these flaws, the article proffers a series of improvement strategies, encompassing the refinement of information disclosure mechanisms, the enhancement of report format construction, the elevation of information comparability, and the fostering of a user-oriented philosophy. These recommendations aim to elevate the overall quality of financial statements, augmenting their transparency and utility in the market, thereby furnishing enterprises, investors, and regulatory bodies with more accurate and dependable informational support.

This article delves into the current state and inherent deficiencies of corporate financial statement presentation, thoroughly examining issues pertaining to information disclosure, format standardization, comparability, and user orientation. Through a comprehensive analysis of actual cases and literature, the piece highlights the shortcomings in the transparency and decision-utility of existing financial statement presentation. In response to these flaws, the article proffers a series of improvement strategies, encompassing the refinement of information disclosure mechanisms, the enhancement of report format construction, the elevation of information comparability, and the fostering of a user-oriented philosophy. These recommendations aim to elevate the overall quality of financial statements, augmenting their transparency and utility in the market, thereby furnishing enterprises, investors, and regulatory bodies with more accurate and dependable informational support.

BackgroundMany older adults experience disabling back and leg pain. This study aimed to identify factors associated with back pain causing severe interference with daily activities over 2 years.MethodsParticipants were 2,109 community-dwelling adults (aged 65–100 years; mean age 74.2 (SD 6.3)) enrolled in a prospective cohort study who reported back pain at baseline and provided back pain data at 2 years follow-up. Baseline data included demographics, socio-economic factors, back pain presentation and age-associated adverse health states (e.g. frailty, falls, walking confidence). At 2 years follow-up, we asked if they were currently experiencing back pain and if so, asked participants to rate how much their back pain interfered with their daily activities on a scale of 0–10. Severe back pain interference was defined by a rating of 7 or more. The association between baseline factors and severe back pain interference at two years was assessed using logistic regression models.ResultsAt two years, 77% of participants (1,611/2,109) still reported back pain, 25% (544/2,083) also reported leg pain and 14% (227/1,611) reported severe back pain interference with activities. Improvements in symptoms were observed over the two years follow-up in 880/2,109 participants (41.7%), 41.2% (869/2,109) of participants report no change and worsening symptoms was reported by 17.1% (360/2109) of participants. After adjusting for back pain troublesomeness at baseline, factors associated with reporting severe interference were adequacy of income (careful with money [OR 1.91; 95% CI 1.19–3.06]; prefer not to say [OR 2.22; 95% CI 1.11–4.43]), low endorsement of exercise in later life (OR 1.18; 95% CI 1.02–1.37), neurogenic claudication symptoms (OR 1.68 (95% CI 1.15–2.46)], multisite pain (OR 1.13; 95% CI 1.02–1.24) and low walking confidence (OR 1.15; 95% CI 1.08–1.22).ConclusionAfter adjusting for baseline pain severity, we identified five factors that were associated with severe pain limitation at two years follow-up among a cohort of community dwelling older people reporting back and leg pain. These included other pain characteristics, walking confidence and attitude to activity in later life. We also identified a socioeconomic factor (perceived adequacy of income). Future research should focus on whether identifying individuals using these risk factors in order to intervene improves back pain outcomes for older people.

Abstract Disclosure: J. Case: None. R.V. Chemitiganti: None. D. Suravajjala: None. Autoimmune thyroid disease comprises both hyper- and hypothyroid states including Graves' disease and Hashimoto's thyroiditis, respectively. The predominant antibody activity, demonstrable by thyrotropin receptor antibody, predicts the clinical presentation and treatment; thyrotropin receptor antibodies may act as a stimulatory or inhibitory stimulus upon the thyroid gland recognized as thyroid stimulating antibody(TSAb) and thyroid blocking antibody(TBAb). Rarely patients may transition from a hyperthyroid to a hypothyroid state and vice versa if the predominant antibody activity shifts which may occur due to a variety of mechanisms and characteristics related to each individual patient and treatment course. A 29 year old female presented to establish care for autoimmune thyroiditis. She was diagnosed with Graves' disease at age 19 when pregnant and treated with propylthiouracil; she switched to methimazole for the next six years when her thyroid function normalized and therapy discontinued. Two years later she became concerned with weight gain and her thyroid function was reevaluated demonstrating hypothyroidism and she was treated with levothyroxine 25mcg daily until presentation. Further labwork revealed undetectable TSI, and TPO antibody elevated at 177 u/mL. She became clinically and biochemically euthyroid on levothyroxine 50mcg daily. Switching between hyper- and hypothyroid states is a rare occurrence among patients with may attributable factors. Both antithyroid drugs including methimazole as well as replacement therapy with levothyroxine may alter the antibody milieu and so the predominant ratio and activity among TSAb and TBAb thereby leading to a shift in clinical presentation and thyroid state. Pregnancy may lead to hemodilution contributing to lessening of autoimmune activity which may return following delivery leading typically to a shift from TSAb to TBAb. Uncontrolled hyper- and hypothyroidism may affect dendritic activity leading to altered presentation and increased immune reactivity. The unlikely occurrence of switching from a hyperthyroid to a hypothyroid state based upon autoimmunity as in this patient was likely affected these factors. Recognition of this potential transition and associated factors would lead to beneficial monitoring and possibly development of assays more attuned to this phenomenon with better capability in maintaining a euthyroid state and potentially predicting a transition. Presentation: 6/3/2024

Background: Psoriasis is a persistent immune system disorder that influences the skin, leading to red, flaky patches that can be painful and irritated. Objective: Traditional treatments for psoriasis, such as topical creams and oral medications, may be effective but also have potential side effects. Herbal remedies have been used for centuries to treat skin conditions, and advancements in nanotechnology have led to the development of herbal nanoformulations that offer several advantages over traditional herbal remedies, such as efficacy, safety, and targeted delivery. Methods: The studies and reviews published under the title were looked up in several databases (including PubMed, Elsevier, and Google Scholar). Results: Several herbal nanoformulations, including those containing curcumin, aloe vera, and neem, have been shown to exhibit anti-inflammatory and immunomodulatory impacts, which will be useful within the treatment of psoriasis. However, more study is required to decide the efficacy and safety of these details, as well as the optimal dosing, duration of treatment, and potential side effects. Conclusion: Overall, herbal nanoformulations represent a promising area of research for the treatment of psoriasis, and may offer a safe and effective alternative or adjunct therapy to conventional treatments. This review article summarizes the present state of information for the herbal nanoformulations role in the treatment of psoriasis and their future perspectives.

Background:: Sustainability concerns are rapidly being acknowledged as a key concern for hospitality sectors worldwide. Sustainable initiatives immediately contribute to improved organizational performance in terms of utility consumption, waste management, and regulatory compliance, resulting in cost-effectiveness and competitive advantage through distinctiveness. Objective:: The purpose of the study is to analyze and summarize the motivations, indicators, and barriers towards applications of sustainable initiatives and modern technologies in the hospitality industry using the existing literature to develop a current understanding of the subject and know the way the current industry is thinking about it. Method:: This study is a combination of systematic and bibliometric review, where the systematic review was based on selected articles from reputed journal databases, and the bibliometric review was conducted using VOS viewer and web of science database for a period of 20 years (2002- 2022) Seven research questions were framed and answered for the systematic review. Result:: By describing the motivations, barriers, and impacts of implementing sustainability initiatives and cutting-edge technologies like AI and machine learning in the hospitality sector, the study helps practitioners and academics understand its present state for robust research. The current condition of such implantations in the hospitality sector is also discussed. Conclusion:: This study adds value by shedding light on the perspective of sustainability in the hospitality industry by considering the recommendations and practical advice for hotel management suggested in the existing literature about the application of current sustainability innovations and effective sustainability initiatives in hotel management.

In 2024 Indonesia will hold General Elections (PEMILU) to elect the President and Vice President. Interestingly, even though the election has been completed, there are still controversial matters that lead to endless debates, namely related to the polemic over the validity of the determination of Gibran Rakabuming Raka as the Vice Presidential Candidate of the Republic of Indonesia. This study aims to provide an objective picture of the validity from the point of view of state administrative law with a theoretical approach that refers to the purpose of presenting state administrative law. The research method used is normative juridical research, using primary materials in the form of KPU Regulations, KPU Decisions, and MK Decisions 90/PUUXXI/2023 and secondary materials in the form of books, journal articles, and relevant online sources. The findings of this study show that the determination of Gibran Rakabuming Raka as the Vice Presidential Candidate of the Republic of Indonesia is contrary to Formal and Material rules in State Administrative Law.

The article is devoted to the influence that concept of state has upon understand­ing of state interest in structural realism. Turns out that state interest in structural realism is imposed upon state by the very structure of international system, which may be one of key factors in normative turn of structural realism. We claim that it is only possible because structural realism tries to ignore inner structure of the state or present it as “contingent” factors “outside the system”. Presenting state as an “individual” allows to ignore its de facto interests and present struc­ture-formed interests as objective and desirable ones. The claim that the struc­ture-imposed interests are the only authentic and important ones in international relations transforms structural realism into normative theory that demands the states to act uniformly according to these interests. The main danger is that structural realism has potential to raise distrust among states, while removing re­sponsibility from statesmen, who are fulfilling “objective” interests in their states.

Background: Lean Six Sigma is a fact-based, data-driven approach that avoids mistakes to improve quality and efficiency. Artificial intelligence (AI) is now evident in lean six sigma applications. AI waste elimination solutions can eliminate large amounts of waste that LSS could not. In lean six sigma, six sigma tackles process variance, whereas lean reduces waste to improve process quality and efficiency. Objective: To describe new pieces, trends, and the adoption and implementation of new technologies like AI by examining the current literature across multiple aspects for a more instructive and piquant viewpoint. Methods: This study is a combination of systematic and bibliometric review, where the systematic review was based on a class framework by selecting 97 articles from reputed journal databases, and the bibliometric review was conducted using a VOS viewer and web of science database for a period of 15 years (2007-2022). Results: By describing LSS's historical evolution, major concerns, prevalent research approaches, and application areas, the study helps practitioners and academics understand its present state for robust research. AI and other cutting-edge technologies help discover non-value-added operations that are difficult to recognize manually. Conclusion: This study has revealed the critical success factors for deploying LSS in numerous businesses. The motivations, barriers, and limits in the direction of the application of LSS are also discussed. The research trends in implementing modern technologies like AI showed a green wave. Future research may emphasize and dominate LSS implementation issues with modern technologies like AI.

Subject. The article investigates the state of presentation of information on depreciation and impairment of non-financial assets by Russian universities, and prospects for its improvement. Objectives. The aim is to summarize and systematize the provisions of the current federal accounting standards for public finance, governing the depreciation and impairment of non-financial assets, study the practice of accounting policy formation by higher education institutions in relation to non-financial assets based on the specifics of these organizations’ activities. Methods. The study employs observation, comparison, generalization, and interpretation, the analysis of the content of federal accounting standards for public finance, accounting policies for depreciation and impairment of non-financial assets of 26 higher education institutions in Russia. Results. Most higher education institutions do not consider the procedure for calculating depreciation of the structural part of fixed assets. Some universities apply the procedure for calculating amortization of intangibles that does not comply with the provisions of the federal accounting standards for public finance in relation to intangible assets with indefinite useful life. No university identifies signs of impairment or reflects non-financial assets less impairment losses in accounting statements, thus preventing their objective evaluation. Conclusions. I offered a unified approach to identifying external and internal signs of possible impairment of assets by higher education institutions, given the specifics of their activities. The paper established a sequence of actions when testing a cash-generating asset for impairment.

Abstract: All the standard anti-tubercular drugs, well established as standard therapy, are preferentially available in formulations compliant with the young adult population. However, their use in the paediatric and geriatric populations is confronted with issues, such as a high likelihood of incorrect dose administration due to practices like dosage form fracture and splitting. This may lead to drug resistance due to misuse and in-accurate dosage administration, the most dreaded and difficult-to-treat stage of tuberculosis. : Poor patient compliance and adherence are major issues with the conventional line of therapy. This burden may be more significant in resource-constrained settings, necessitating the creation of simple formulations that are both geriatric and child-friendly. An extensive literature survey has been conducted in this study using databases of Google Scholar, PubMed, and Research Gate, with a focus on specific research works on oro-dispersible films, tablets, and wafer technology loaded with anti-tuberculosis drugs from 2022 to 2010. : Mouth dissolving formulation technology is a very novel approach in the arena of tuberculosis therapy. This may pave the way for future researchers to develop different mouth dissolving formulations to treat both pulmonary and extra-tuberculosis. This review paper has summarized all the formulation approaches alongside the present state of the art in tuberculosis therapy using mouth dissolving formulations.