Postoperative Weight Change Research Articles

Simply modified no-scalpel vasectomy (percutaneous vasectomy) — a comparative study against the standard no-scalpel vasectomy

Background and Purpose The simply modified no-scalpel vasectomy (SMNSV; percutaneous vasectomy) technique was reported to simplify the standard no-scalpel vasectomy (SNSV) procedure. In this report, we introduce our experiences with SMNSV in comparison with the SNSV. Materials and Methods Between July 1999 and June 2002, 417 men were prospectively randomized to be vasectomized at the Taipei Medical University Hospital: 215 acceptors underwent the SNSV and the remaining 202 received the SMNSV. Using the no-scalpel vasectomy instruments in a percutaneous fashion, the sharp no-scalpel hemostat punctures the skin directly instead of fixating the vas to the skin with the use of a ring clamp, as done in SNSV. The vas is then grasped with the ringed instrument instead of piercing the vas and performing the supination maneuver, as described for SNSV. The intraoperative conditions of each group were recorded. The postoperative pain and life conditions were self-reported. The pain level was assessed using a 10-cm visual analogue scale under various situations. Results The time required for the SMNSV technique was less than that for the SNSV technique (p<.05). There were no significant differences between the two groups with respect to incision length, postoperative pain, pain at coitus, time of return to work, time of resuming intercourse, self-reported satisfaction in sexual life, postoperative psychological status, postoperative body weight change and postoperative complications (p>.05 for all items). Conclusions The simply modified vasectomy technique simplifies the SNSV technique. It combines the minimally invasive nature of SNSV with the simplicity of classical vasectomy while conserving many comparable advantages.

Is portal venous outflow better than systemic venous outflow in small bowel transplantation? Experimental study in syngeneic rats

Background/Purpose Blood drainage of the graft into the recipient portal vein reestablishes the physiological venous outflow after small bowel transplantation (SBT). However, although this approach is likely beneficial for the host, it may be technically more demanding making portocaval venous drainage the preferred arrangement during human SBT. The aim of this study was to examine in a syngeneic model of SBT the possible benefits of portoportal anastomosis (PPA) vs portocaval anastomosis (PCA) in terms of body and organ weights and bacterial translocation. Methods Syngeneic SBT was carried out in 25 Brown-Norway male rats weighing 249 ± 17.5 g using either PPA (n = 13) or PCA (n = 12). Half the animals in each group were killed, respectively, on postoperative day 2 or 7. Liver, spleen, and lungs were weighed and under sterile conditions the regional lymph nodes were excised. The nodes and venous samples from the cava and portal veins were cultured for aerobes and anaerobes. Bacterial components were detected in blood by polymerase chain reaction. The findings in both groups were compared by χ 2 or Mann-Whitney U tests. Results Mean postoperative body weight change was −3.6% ± 1.5% in PPA and −6.0% ± 1.2% in PCA animals (ns) on day 2 and −6.5% ± 2.6% and −8.0% ± 5.0% (ns) on day 7. Liver, spleen, and lung weights were not significantly different between both groups on either end point. Gram-negative enteric bacteria were found in 3 of 7 PCA animals and 2 of 6 PPA animals at day 2 (ns) and in 1 of 6 and 4 of 6 on day 7 (ns). Aerobic gram-positive bacteria were found in 1 of 7 and 1 of 6 (ns), 3 of 6 and 3 of 6 (ns), respectively, in the 4 groups. Most positive cultures corresponded to portal blood and lymph node samples. There were no anaerobic growths. Conclusions - No body or organ weight change suggesting significant functional advantages of one technical alternative over the other could be demonstrated. - Bacterial translocation in the absence of rejection was frequent after SBT independently of the variety of venous outflow used. No difference in bacterial translocation between both anastomosis could be demonstrated. - Orthotopic venous drainage did not seem to be advantageous in the present experimental setting.

Duodenal-preserving resection of the head of the pancreas and pancreatic head resection with second-portion duodenectomy for benign lesions, low-grade malignancies, and early carcinoma involving the periampullary region.

Duodenal-preserving resection of the head of the pancreas (DPRHP) and pancreas head resection with segmental duodenectomy (PHRSD) can be alternatives to standard pancreaticoduodenectomy for benign periampullary lesions. Retrospective analysis of patients requiring surgery for benign and borderline malignant tumors of the periampullary region. Tertiary care referral center. Duodenal-preserving resection of the head of the pancreas (n = 8) and PHRSD (n = 7) were performed in 15 patients with a preoperative diagnosis of benign and borderline malignant tumors of the periampullary region (ie, 11 pancreas head lesions [2 intraductal papillary mucinous tumors, 4 serous cystadenomas, 2 insulinomas, 1 epidermal cyst, 1 metastatic renal cell carcinoma, 1 nonfunctioning islet cell tumor/parapaillary] and 4 duodenal lesions [3 adenomas and 1 adenocarcinoma]). Surgical factors (operation time and blood loss), postoperative complication, postoperative pancreatic insufficiency (eg, development of diabetes mellitus and steatorrhea or elevated stool elastase values), weight change, and recurrence of disease. No differences were noted in the mean operation time and estimated blood loss between the 2 procedures. Major postoperative complication constituted the following: bile duct stricture (n = 1) in DPRHP and delayed gastric emptying (n = 1) and postoperative bleeding (n = 1) in PHRSD. Newly developed diabetes mellitus occurred in 1 patient. Exocrine pancreatic insufficiency (steatorrhea) was observed in 1 patient after PHRSD. Patients with early duodenal carcinoma and intraductal papillary mucinous tumors with a borderline malignancy are still alive without evidence of recurrence. There was no hospital or long-term mortality. Duodenal-preserving resection of the head of the pancreas is recommended first for a benign or low-grade, early malignant pancreatic head lesion; PHRSD can be an option for a lesion of the ampullary-parapapillary duodenal area as well as the pancreatic head. Duodenal-preserving resection of the head of the pancreas can be converted to PHRSD if ischemia of the second portion of the duodenum occurs. We found benign periampullary lesions could be conservatively treated with DPRHP and PHRSD, which could substitute for classic pancreaticoduodenectomy.

Post-operative obesity and cachexia are risk factors for post heart transplant morbidity and mortality: a multi-institutional study of post-operative weight change

Post-operative obesity and cachexia are risk factors for post heart transplant morbidity and mortality: a multi-institutional study of post-operative weight change

Formation of vesicovaginal fistulas in laparoscopic hysterectomy with electrosurgically induced cystotomy in female mongrel dogs

Objective: The aim of this pilot study was to investigate the relationship between various types of laparoscopic bladder injuries and vesicovaginal fistula formation in an animal model. Study Design: Sixteen female mongrel dogs were divided into four groups. All animals underwent a laparoscopic hysterectomy. Those assigned to group 1 sustained a 1-cm bipolar cautery injury to the bladder base without perforation of the bladder mucosa. Animals in group 2 had two sutures of 2-0 polyglactin placed to incorporate the full thickness of the bladder wall and the vaginal cuff. The bladder injury to group 3 was a 1-cm bladder base laceration induced with monopolar cautery, repaired with two interrupted 2-0 polyglactin sutures. Group 4 underwent a bladder base cystotomy similar to those in group 3, with the closure incorporating the anterior vaginal wall. Animals were killed and necropsy was performed at least 28 days after surgery. The bladder and vagina of each animal were harvested en bloc. Evidence of a vesicovaginal fistula was determined by two methods: transurethral injection of indigo carmine solution under direct visualization and air injection during underwater submersion. Results: The four groups were comparable with regard to postoperative weight changes. No mongrels showed signs of infection or sepsis. Inspection of the harvested bladder and vagina revealed no fistulas in groups 1 and 2. One mongrel from group 3 and one from group 4 had evidence of a vesicovaginal fistula. With 95% CIs, the fistula rate would be at least 2% and as high as 38% if a larger study had been undertaken. Conclusion: The female mongrel is the first identified animal model of vesicovaginal fistula formation. In this setting, an electrosurgically induced cystotomy and repair of the bladder during the performance of a laparoscopic hysterectomy is associated with the formation of postoperative vesicovaginal fistulas. (Am J Obstet Gynecol 2002;187:1510-4.)

Obesity-Associated Disorders Before and After Weight Reduction by Vertical Banded Gastroplasty in Morbidly vs Super Obese Individuals

The amount of excess weight which must be lost in order to cure or to improve disorders associated with obesity remains unknown. This study was designed to compare super obese and morbidly obese patients in terms of weight reduction following VBG and to investigate the effects of postoperative weight changes to preexisting co-morbidities. 125 patients underwent VBG. Group A consisted of 80 morbidly obese patients (64%) and group B consisted of 45 super obese patients (36%). Preoperative examination was planned to identify and determine the severity of any disorders associated with obesity, that the patients may have had. Following VBG, all patients were followed-up at regular time periods, for at least 2 and up to 4 years. The progress of preexisting co-morbidities was evaluated and carefully recorded. Among the 80 patients of Group A, there were 240 total co-morbidities (3 per patient), and in group B there were 196 co-morbidities (4.35 per patient) preoperatively. Dyspnea during fatigue and arthritis were found at statistically higher incidence in the super obese category. At the end of the second postoperative year, greater weight loss in terms of number kilograms was seen in patients in group B, but these patients did not reach a BMI lower than 35, while patients in group A had mean BMI below 30. In group A, 66% of the co-morbidities completely resolved, 19% significantly diminished and 15% remain unchanged. In group B, the respective percentages were 53%, 27.5% and 19.5%. However, after weight reduction by VBG a significant number of co-morbidities remain in the super obese patients (92 or 2.044 per/patient), and this is believed to be due to the greater remaining excess weight. Reduction of body weight by VBG is associated with resolution or improvement of a significant number of the obesity-associated disorders. However, super obese patients remain obese after surgery, and this results in two-fold higher remaining morbidity.

Quality of life after laparoscopic adjustable gastric banding for severe obesity: postoperative and retrospective preoperative evaluations.

The aim of this study was to examine postoperative as well as retrospective preoperative evaluations of multiple dimensions of quality of life of patients with morbid obesity after laparascopic adjustable gastric banding (LAGB). 12 to 38 months after LAGB, 74 consecutive patients (64 female, 10 male, mean age 36.6 years, age range 23-56) filled out the RAND-36 Health Survey questionnaire to evaluate their current postoperative as well as their past preoperative quality of life. Pre- to 1 year postoperative weight reduction (127.5 to 100.7 kg) and change of BMI (45.2 to 35.6 kg/m2) were highly significant (p<0.001). As compared to age reference groups, the preoperative quality of life was evaluated very poor (p<0.002), postoperative psychological and social quality of life were about normal (all p's >0.10), and postoperative physical functioning (p=0.04), vitality (p=0.01) and general health (p=0.03) were below normal. No differences were found between postoperative evaluations of patient groups with varying postoperative follow-up duration, but patients in the second year after surgery evaluated some aspects of their preoperative quality of life as poorer than patients in the third year after surgery. Postoperative psychosocial quality is at a level that may be expected to motivate patients to consolidate the surgically established weight reduction, but attention should be paid to the physical condition. Since the relative gain in quality of life as experienced by patients tends to be evaluated less with a longer duration of the postoperative interval, the risk of relapse may increase with passage of time.

Changes in weight and body composition after orthognathic surgery and jaw fractures: a comparison of miniplates and intermaxillary fixation

Objectives—To compare the changes in postoperative weight and body composition following orthognathic surgery or jaw fractures treated by intermaxillary fixation (IMF) or miniplate osteosynthesis. Design—A 4-month non-randomised prospective pilot study. Body composition was assessed using the 4 site skinfold thickness technique. The fixation method used in each case was dependent on clinical criteria alone. Setting—Oral and maxillofacial surgery units at St James's University Hospital and the General Infirmary at Leeds. Subjects—All patients were eligible for inclusion in the study if they had sustained a jaw fracture or had undergone orthognathic surgery. Patients were excluded if they had sustained polytrauma, if their sole orthognathic surgery procedure was a genioplasty and if the author was not directly involved in their management. The final study group consisted of 22 patients, 18 following surgical correction of jaw fractures and 4 following elective orthognathic surgery. Thirteen patients were managed with intermaxillary fixation and 9 patients were treated with miniplate osteosynthesis. Main outcome measures—Weight, lean body mass, total body water, fat and water free lean body mass, 1 week and 6 weeks postoperatively. Results—There was no significant difference in weight loss or body composition changes between the plated and non plated groups at 1 week postoperatively. However, by 6 weeks postoperatively the IMF group had lost significantly more weight (4.5 kg) than the plated group (1.1 kg). In the plated group this weight loss resulted entirely from a loss of lean body mass (77% water), whereas in,the other group it resulted from a fat loss of 1.2 kg plus a lean body mass loss of 3.3 kg (73% o water). Estimated protein losses were 0.9 kg for the IMF group and 0.3 kg for the plated group. Conclusions—Intermaxillary fixation compromises nutritional status in the early postoperative period leading to loss of water, fat and protein. The results of this pilot study suggest that further investigation of postoperative weight and body composition changes after oral and maxillofacial operations is indicated.

Agricultural modernization in market and planned economies: The German experience

Retrospective comparative study.The effect of spine surgery on postoperative weight loss or weight gain in overweight and obese spinal deformity patients is unknown.To evaluate the postoperative outcomes and weight changes in adult patients undergoing spinal deformity surgery.A total of 104 adult patients undergoing primary spinal deformity surgery were enrolled. All patients had a minimum 2-year follow-up (average, 50.1 months). Preoperative and latest follow-up, body mass index (BMI), Oswestry Disability Index, Scoliosis Research Society (SRS)-22 self-image and SRS outcomes scores were collected. Instrumented levels, estimated blood loss, major and minor complications, length of hospitalization, and hospital discharge status were also reviewed and compared.A total of 66 patients were overweight (BMI > 25–29.9; average, 26.9) (Group OW), whereas 38 patients were obese (BMI > 30; average, 33.5) (Group OB). The average age was 54.5 in Group OW and 48.6 in Group OB (p < .01). Postoperatively, significant changes were not found in the BMI for Group OW, 27.2 (26.9–27.2; p < .39), and for Group OB, 35 (33.5–35; p < .06). Postoperatively, significant improvements were seen in both groups for Oswestry Disability Index (36.1–21.8, Group OW; 44.1–24.4, Group OB; p <.001), SRS self-image (2.9–3.7, Group OW; 2.6–3.8, Group OB; p < .001) and SRS score (3.1–3.8, Group OW; 2.9–3.8, Group OB; p < .001). There were no significant differences in complications between groups.As a group, overweight and obese primary spinal deformity patients did not demonstrate significant weight gain or weight loss from preoperative to latest follow-up. However, both overweight and obese patients had significant improvements in outcome scores at latest follow-up and equivalent rates of complications.