India is currently having a deceased donation rate of 0.05–0.08 per million population. The National Organ and Tissue Transplant Programme have planned strategies to improve organ donation by creating awareness and capacity building. There is a great need to assess the knowledge regarding organ donation among the general population. In our community, so many myths and misconceptions people have regarding organ donation. This prevents people to come forward to donate their organs whenever the need arises. When we educate and motivate the student population they will not only donate their organs but also motivate others also to donate their organs to form a very healthy society. Hence, this study has been undertaken to assess the knowledge, attitude, and practice regarding organ donation among college students as they are going to be tomorrow’s responsible citizens of our nation. The objectives of the study were to assess the pre-test and post-test levels of knowledge and attitude, to assess the effectiveness of Video-assisted teaching, to find out the association between post-test levels of knowledge and attitude, and to assess the correlation between knowledge and attitude regarding organ Donation. The research design used was a pre-experimental group pre-test and post-test design. The data collection tool was validated by General Physician and the four Nursing experts. Reliability was established by the test-retest method, r = 0.8 for the structured knowledge questionnaire and 0.87 for the attitude rating scale. The samples for the study were chosen by using the purposive sampling technique, and 40 samples were selected. Data was collected by using a structured knowledge questionnaire and an attitude rating scale. Data was collected for a period of one month. The data collected were edited, tabulated, analyzed, and interpreted manually. The obtained overall post-test Mean for knowledge was 24.37, SD 7.8, and for attitude Post-the test Mean was 23 SD 6.56. The obtained mean difference for knowledge was 17.62 and the attitude was 6 and the paired-test value for knowledge was 13.15 for knowledge and for attitude it was 4.47 significant at the level of P <0.05. The demographic variables Residential area, Sources of information regarding organ donation, and the persons to whom you are willing to donate were associated with post-test scores on knowledge, and the demographic variables Sex, residential area, and persons whom you are willing to donate were associated with the post-test scores on attitude. Other demographic variables were not significant with the post-test scores on knowledge and attitude. The study's findings revealed that there was a significant difference in pre-test and post-test scores on the level of knowledge and attitude regarding organ donation and a significant association between the post-test level of knowledge and attitude with their selected demographic variables.
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