Postoperative Nausea And Vomiting In Group Research Articles

Effect of Auricular Acupressure Therapy for the Prevention of Postoperative Nausea and Vomiting After Gynecological Surgery

Postoperative nausea and vomiting (PONV) is still a troubling problem in patients who undergo gynecological surgery, especially in patients using morphine for patient-controlled analgesia (PCA). In this study, we investigated whether auricular acupressure therapy reduced the incidence of PONV. A total of 150 female patients (ASA I-II, aged 18-65 years) scheduled to undergo myomectomy or hysterectomy were enrolled in this double-blind, placebo-controlled study and randomly assigned to one of three groups. In groups I and II, we taped seeds of Wangbuliuxing onto auricular points (two sets of four) and asked patients to compress these points four times a day. Group III acted as the control group. Data were available for 124 patients. The incidence of PONV in group I was significantly decreased in the first 2 days (day 1: 16%; day 2: 12%) compared with group II (day 1: 42%, p = 0.021; day 2: 32%, p = 0.048) and group III (day 1: 40%, p = 0.030; day 2: 35%, p = 0.023). Auricular acupressure therapy at the shenmen, jiaogan, wei, and pizhixia points prevented PONV after gynecological surgery with PCA.

A Comparison of the Efficacy and Safety of Tropisetron and Tropisetron Plus Dexamethasone as Antiemetics for Elective Thyroidectomy

Background: Thyroidectomy is associated with a relatively high incidence of postoperative nausea and vomiting (PONV) ranging from 63% to 84%. In this study, we evaluated the safety and the antiemetic effects of tropisetron 30μg/kg or tropisetron 30μg/kg plus dexamethasone 5 mg in patients undergoing thyroidectomy under a standard anesthetic technique without narcotics. Methods: Sixty-eight patients undergoing thyroidectomy were randomized to receive a placebo (Group C, n = 28), tropisetron 30μg/kg (Group T, n = 23) or tropisetron 30μg/kg plus dexamethasone 5 mg (Group T + D, n = 17) IV over 2-5 minutes immediately before the induction of anesthesia. The effects of these regimens on the development of PONV, adverse events and need for rescue antiemetics were analyzed for the 0 to 1 hour and 1 to 24 hours postoperative periods. Results: In the 0 to 1 hour postoperative periods, the incidence of PONV in group C, T and T + D was 35.7%, 17.4% and 17.6% respectively, which showed no significant difference among the three groups (P > 0.05). In the same period, the incidence of retching or vomiting in Group C, T and T + D was 14.3%, 0% and 0% respectively, which showed a significantly lower incidence in Group T and T + D than Group C (P 0.05). During the first 24 hours postoperatively, the overall incidences of PONV was 67.9% for group C, 60.9% for group T and 58.8% for group T + D, which showed no siginificant difference among the three groups (P > 0.05). Group T + D patients had more headache compared to other groups, but there was no significant difference in the

Effect of Propofol on the Incidence of Postoperative Nausea and Vomiting after Minor Orthopedic Surgery

Background : The aim of the present study is to evaluate the effect of propofol on the incidence of postoperative nausea and vomiting (PONV) during the first 24 hours after minor orthopedic surgery using general anesthesia. Methods : We studied 66 healthy female patients (aged 20∼67 years old). The patients were randomly divided into the two groups: (i) Group P (n=33): Anesthesia was induced with propofol and fentanyl, and maintained with continuous infusion of propofol. (ii) Group E (n=33): Anesthesia was induced with thiopental and fentanyl, and maintained with enflurane. We compared the incidence and severity of PONV at 6 and 24 hours after the operation between the two groups. Results : The incidence and severity of PONV in Group P was significantly lower than in Group E during the first 6 hours after the operation (p＜0.05). However, after 6 hours, there was no significant differences between the two groups. Conclusion : In the early postoperative period, the use of propofol prevents PONV. (Korean J Anesthesiol 1999; 36: 402∼406)