Pittsburgh Sleep Quality Index Questionnaire Research Articles

Sleep quality and mental health among Chinese nurses after the COVID-19 pandemic: A moderated model.

In the specialized nursing setting, nurses are susceptible to developing negative mental health issues. Such conditions among nurses can potentially result in unfavorable medical outcomes. Consequently, this study aims to explore the role of social support in regulating between sleep and mental health in nurses. A cross-sectional study was carried out in September 2022 on 1219 nurses in Quanzhou. The study comprised general demographic information and utilized various questionnaires, namely the Social Support Rate Scale (SSRS), Pittsburgh Sleep Quality Index Questionnaire (PSQI), Generalized Anxiety Disorder Questionnaire (GAD-7), and Patient Health Questionnaire-9 (PHQ-9). The data analysis was performed using t-tests, ANOVAs, Pearsons correlations and hierarchical regression analyses in SPSS software. Results show that significant associations of sleep quality and social support with anxiety and depression. Simple slope analysis shows that under low levels of social support, sleep quality has a positive impact on anxiety(β = 0.598) and depression(β = 0.851), and the impact is significant. Under high levels of social support, sleep quality also has a positive impact on anxiety(β = 0.462) and depression(β = 0.578), but the impact is smaller. This indicates that as the level of social support increases, the positive predictive effect of sleep quality on anxiety and depression gradually diminishes. Social support has the potential to alter the impact of sleep quality on anxiety and depression. Therefore, healthcare policymakers need to focus on enhancing the level of social support and mitigating the impact of poor sleep on anxiety and depression.

Quality of sleep in individuals with systemic sclerosis and its correlation with functional disability and quality of life: a cross-sectional study.

This study aimed to evaluate the quality of sleep in individuals with systemic sclerosis and its correlation with the quality of life and disability. This is a cross-sectional study, carried out in a tertiary service of a university hospital. Inclusion criteria were diagnosis of systemic sclerosis according to the criteria of the American College of Rheumatology/European League Against Rheumatism 2013 or the preliminary criteria of the American College of Rheumatology 1980, age ≥ 18 years; regularly monitored at the outpatient clinic of rheumatology. Clinical and demographic data of the patients were obtained through a structured interview and evaluation of the medical records. Sleep quality was assessed using the Pittsburgh Sleep Quality Index questionnaire, daytime sleepiness using the Epworth Sleepiness Scale, quality of life using 12-item short-form health survey, and disability using the scleroderma health assessment questionnaire. A total of 50 patients with systemic sclerosis were included, with 92% female, mean age 48.9 years, mean disease duration 8.9 years, and 60% limited cutaneous form. Most systemic sclerosis patients (84%) have poor sleep quality and 20% have excessive daytime sleepiness. There was a significant negative correlation between Pittsburgh Sleep Quality Index and the physical and mental components of the 12-item short-form health survey (r=-0.42, p=0.003 and r=-0.43, p=0.002, respectively) and a positive correlation with the scleroderma health assessment questionnaire (r=0.52, p=<0.001). This study showed that poor sleep quality is a very common finding among systemic sclerosis patients, and it negatively affects both the quality of life and the degree of disability. Sleep quality is an unmet need in patients with systemic sclerosis Poor sleep quality is very common in patients with systemic sclerosis Poor sleep quality correlated with worse quality of life and greater disability.

Effect of Smartphone Usage during Night Time on Sleep Patterns of Young Adults: A Cross-sectional Observational Study

Introduction: Excessive smartphone usage among adolescents and young adults has been consistently linked to poor sleep. Moreover, smartphone overuse has been associated with daytime tiredness, longer sleeps latency, and reduced sleep duration. The significance of addressing poor sleep among adolescents and young adults is underscored by recent research linking it to adverse physical and psychological health outcomes, such as mood disturbances, impaired cognitive function, and increased risk incidence of hypertension and diabetes. Aim: To evaluate the effects of smartphone usage on sleep quality among individuals using Pittsburgh Sleep Quality Index (PSQI) and hypnogram data. Materials and Methods: In this cross-sectional observational study, sleep patterns were assessed using the PSQI questionnaire and Prime Nap sleep tracker app (version 1.1.4). The study was conducted by Deccan College of Medical Sciences, Hyderabad, Telangana, India. The data was collected in the form of a hypnogram and the study was conducted in the participants’ homes (under domicile conditions) in the city of Hyderabad, Telangana, India from March 2020 to April 2020. A total of 60 participants (both male and female) in the age group of 15-25 years were recruited and divided into two groups: one comprising 30 individuals with regular prolonged exposure to smartphone screens at night, and the other consisting of 30 individuals who experienced minimal or no smartphone exposure once they prepared to sleep. Descriptive statistics were applied to the collected data using Microsoft Excel and IBM Statistical Package for Social Sciences (SPSS) for Windows version 25.0. Results: Adding up the average scores of the seven factors gives a global PSQI score from 0 to 21, with 0-4 indicating good sleep and 5-21 indicating poor sleep. Among those who used smartphones regularly at night time, 20 participants (66.67%) had PSQI score &gt;5 and poor sleep quality, 24 participants (80%) had prolonged sleep latency, 18 participants (60%) had poor sleep duration, 27 participants (90%) had sleep disturbances, and 22 participants (73.33%) had increased daytime dysfunction. Hypnogram abnormalities were seen in &gt;15 participants (50%) of subjects. Conclusion: The prevalence of smartphone addiction is widely acknowledged in the medical literature, highlighting the need for its assessment, especially among adolescents and young adults. The study reveals that poor sleeping habits among participants were attributable either to a lack of awareness or neglect. By recognising the importance of adequate sleep, improvement in the quality of daily activities can be made by reducing daily screen time, consequently alleviating both physical and mental stress. Furthermore, the findings have implications for individuals whose work involves prolonged exposure to computer screens, especially during night time.

Washed Microbiota Transplantation Improves the Sleep Quality in Patients with Inflammatory Bowel Disease.

There is scarce evidence to support the effectiveness of faecal microbiota transplantation (FMT) in improving sleep among individuals with inflammatory bowel disease (IBD). Our study aimed to evaluate the effect of washed microbiota transplantation (WMT) (the new method of FMT) on the sleep of patients with IBD in short term. This prospective study was conducted as part of two interventional clinical trials (starting on February 2013 and expected to end on December 2025) and placed significant emphasis on evaluating sleep quality in patients with IBD. To measure subjective sleep, we used the Pittsburgh sleep quality index (PSQI). The primary endpoint was the PSQI score one month after WMT. This stage study included 52 eligible patients evaluated by PSQI questionnaire who underwent WMT from January 2020 to March 2021 and 47 patients were enrolled for analysis. The age of the patients ranged from 13 to 60 years, with a mean of 33.4 years, and 57.4% (25/47) of the patients were male. The PSQI scores for all 47 patients one month after undergoing WMT were significantly lower (Cohen d = 0.59, p < 0.001) compared to the baseline. Moreover, baseline PSQI score was correlated with the difference value of the PSQI score before and after WMT (post-PSQI minus pre-PSQI) (r = 0.61, p < 0.05). The study suggests that WMT might be a helpful intervention for improving the sleep quality of patients with IBD, encouraging clinicians to consider its use in clinical practice for addressing poor sleep in IBD patients. ClinicalTrials.gov; ID: NCT01793831, NCT01790061.

Factors associated with poor sleep quality among dental students in Malaysia.

Good sleep quality is crucial for dental students as they must have optimal cognitive function, memory, and decision-making to accomplish their learning requirements. This study aims to determine sleep quality, its associated factors, and the association between sleep quality and academic performance among dental students in Malaysia. This cross-sectional study involved dental students at four public universities in Malaysia. A validated Pittsburgh Sleep Quality Index (PSQI) questionnaire was used to assess their sleep quality. An additional self-administered questionnaire was employed to obtain the students' sociodemographic profile, lifestyle, and academic performance. The data were analysed using descriptive, chi-square, and multiple logistic regression. Three hundred eighty-four dental students participated in this study. About half of the dental students (51.6%) have poor sleep quality. The mean of sleep hours per night was 5.72 (SD 1.06). The sleep quality was significantly poor among Malay students (P = 0.023), students who stayed at hostel (P = 0.002), and those who consumed caffeinated drinks (P = 0.028). Multiple logistic regression analysis revealed that the poor sleep quality was significantly associated with self-perceived poor academic performance (Adjusted Odds Ratio (AOR) 2.95, 95% CI [1.25-6.96], P-value = 0.013) and students skipping class (AOR 1.70, 95% CI [1.00-2.91], P-value = 0.046). Most of the dental students in Malaysia have poor sleep quality. Ethnicity, accommodation, and caffeine consumption were significantly associated with sleep quality. Awareness to sleep quality among dental students is needed to ensure they are able to cope with the challenging dental school learning environment.

Psychological factors and biochemical indicators influencing sleep disturbance of patients with primary biliary cholangitis in China: a cross-sectional survey analysis.

The impact of primary biliary cholangitis (PBC) on sleep disturbance is relevant to treatment decision-making processes. Studies on sleep disturbance in Chinese patients with PBC are still lacking. We analyzed and compared the health-related quality of life (HRQoL) of 107 PBC patients by using the Pittsburgh Sleep Quality Index (PSQI) questionnaire, Generalized Anxiety Disorder Scale (GAD-7), Patient Health Questionnaire 9 (PHQ-9), Short Form (36) Health Survey Questionnaire (SF-36), Fatigue Visual Analog Scale (F-VAS). Patients' biochemical markers were also collected for correlation analysis with HRQoL. Receiver operating characteristic (ROC) curves and area under the curve (AUCs) were used to determine the diagnostic performance of PSQI, GAD-7, and biochemical markers for assessing the impaired liver function (Child-Pugh B-C) of PBC diagnosis. Sixty-two (57.9%) PBC patients suffered from poor sleep quality (PSQI >5). The global PSQI score was positively correlated with GAD-7 (r = 0.561, p < 0.001), and PHQ-9 scores (r = 0.652, p < 0.001). There was a negative correlation (r = -0.216, p = 0.025) between sleep quality and red blood cell (RBC) count. PBC patients with poor sleep quality had significantly higher GAD-7 scores (5 vs. 0, p < 0.001), PHQ-9 scores (5.5 vs. 0, p < 0.001), and lower albumin levels (39.6 vs. 37.6 g/L, p = 0.040) than those with good sleep quality. Based on the SF-36 scores, PBC patients with poor sleep quality had lower physical functioning scores (85 vs. 80, p = 0.022), role physical scores (100 vs. 75, p = 0.007), and worse mental health (60 vs. 56, p = 0.002) than those with good sleep quality. ROC analyses showed that the AUC and optimal cut-off values of the combination of PSQI, GAD-7, and RBC for assessing the impaired liver function in PBC diagnosis were 0.771 and 0.193, respectively. The sleep disturbance was strongly correlated with the severity of anxiety, depression, and RBC count in PBC patients. Meanwhile, PBC patients with poor sleep had poor HRQoL and lower albumin levels. It is feasible to use the combination of PSQI, GAD-7, and RBC for initial screening of the impaired liver function in PBC. Besides routine blood biochemical and imaging indicators, evaluating mental health-related indicators in PBC patients is imperative.

Assessment of Sleep Quality among Nursing Students on Clinical Posting in a Tertiary Health Facility in North-Western Nigeria

Abstract Context: The sleep quality of nursing students needs to be assessed in the context of their living conditions in order to know the best way to improve any abnormality noted. Aim: To assess the quality of sleep of nursing students and determine its relationship with their conditions of living among other factors. Methods and Material: A cross-sectional descriptive study involving nursing students on postings in a tertiary health facility. The socio-demographic data were collected with the aid of a structured questionnaire. The sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) questionnaires. Statistical Analysis Used: Data were analyzed using the Statistical Product for Service Solution (SPSS) for Windows version 22. Chi-square (χ2) or Fisher’s exact tests were used to determine the association between sleep quality and various parameters. Results: The total participants were 255 with a mean age of 21.5 ± 3.4 yrs and a male to female ratio of 0.4:1. The mean sleep latency period and mean sleep duration were 21.5 ± 14.0 minutes and 6.4 ± 1.4 hours respectively. The mean ESS was 9.8 ± 3.5 indicating an increased tendency for daytime sleepiness. The mean PSQI was 6.2 ± 3.0. Seventy-three percent of the participants were poor sleepers (had scores of ≥5); 7.1% of them had a level of severity needing medical help. The quality of sleep and daytime sleepiness were significantly associated with the number of roommates and source of funding respectively. Conclusion: Most of the participants have poor sleep quality which is significantly associated with the number of roommates and source of funding.

Exercise leads to better sleep in children with inflammatory bowel disease.

The aim of our study was to investigate the effect of an exercise program on health-related quality of life (HRQoL) and sleep quality in children with inflammatory bowel disease (IBD) in remission. A total of 42 pediatric IBD patients in remission were recruited to participate in a 6-month-long home-based exercise program. Their mean age was 15.3 years (with a range of ± 2.08 years) and there were 25 boys. With regard to disease type, 22 had Crohn's disease (CD), 18 had ulcerative colitis (UC), and two had unclassified inflammatory bowel disease (IBD-U). Prior to starting the program, and after its completion, HRQoL was assessed using the IMPACT III questionnaire, and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Patients also wore a triaxial accelerometer for 5 consecutive days before and after the completion of the exercise program to assess physical activity (PA) objectively. Study participants experienced no significant increase in their IMPACT III score (from 147.6 ± 2.7 to 149.6 ± 2.7, p = 0.106) following the completion of the exercise program. The prevalence of impaired sleep quality (PSQI > 5) decreased significantly from 30.9 to 23.8% (p = 0.027). At the baseline, participants' time spent in light PA (LPA) correlated positively with their IMPACT III score (coefficient (coef.) 0.398, p = 0.013). Following the completion of the resistance training program, the changes in the IMPACT III score correlated positively with time spent in moderate-to-vigorous PA (MVPA) (coef. 0.329, p = 0.047) and negatively with changes in PSQI score (coef. -0.493, p = 0.001). The number of children with impaired sleep quality decreased significantly following the completion of a 6-month-long home-based resistance training program but improvements in HRQoL scores did not reach statistical significance.

Lacticaseibacillus paracasei 207-27 alters the microbiota-gut-brain axis to improve wearable device-measured sleep duration in healthy adults: a randomized, double-blind, placebo-controlled trial.

Objective: Probiotics have been reported to exert beneficial effects on sleep through the gut-brain axis. Therefore, this randomized, double-blind, placebo-controlled trial assessed the effects of Lacticaseibacillus paracasei 207-27 supplementation on sleep quality and its safety and potential mechanisms. Method and study design: Healthy adults under mild stress aged 18-35 years consumed low or high doses of L. paracasei 207-27 or a placebo for 28 days. Fecal samples, blood samples, and questionnaires were collected at the baseline and the end of the intervention. Sleep quality was measured using wearable devices and Pittsburgh sleep quality index (PSQI) questionnaire. Serum inflammatory markers, corticotropin-releasing hormone, adrenocorticotropic hormone (ACTH), cortisol (COR), γ-aminobutyric acid, and 5-hydroxytryptamine levels were detected using enzyme-linked immunosorbent assay. The gut microbiota was analyzed using 16S rRNA sequencing and bioinformatics. Short-chain fatty acids levels were detected using gas chromatography-mass spectrometry. Results: Both the low-dose and high-dose groups exhibited significant improvements in wearable device- measured sleep duration compared to the placebo group. The global scores of PSQI in three groups significantly decreased after intervention without statistical difference between groups. At the phylum level, the low-dose group exhibited a higher relative abundance of Bacteroidota and a lower Firmicutes-to-Bacteroidetes (F/B) ratio. At the genus level, two treatment groups had higher relative abundance of Bacteroides and Megamonas, alongside lower levels of Escherichia-Shigella. Furthermore, the low-dose group exhibited significant increases in acetic acid, propionic acid, butyric acid, and valeric acid levels, while two treatment groups exhibited a significant decrease in COR levels. Correlation analysis revealed that the increased levels of acetic acid and butyric acid in the low-dose group may be associated with decreased ACTH. Conclusion: L. paracasei 207-27 administration in healthy adults resulted in improvements in gut microbiota community and sleep duration. The mechanisms might involve modulation of the gut microbiota structure to regulate the function of the gut-brain axis, including increases in SCFA levels and decreases in hypothalamic-pituitary-adrenal axis activity. The Chinese clinical trial registry number is ChiCTR2300069453 (https://www.chictr.org.cn/showproj.html?proj=191193, registered 16 May 2023 - retrospectively registered).

Evaluation of Sleep Quality in Patients with Tinnitus

Aim: Tinnitus is the perception of sound in the absence of auditory stimuli. Tinnitus may affect daily life activities and cause complaints of difficulty in concentration, emotional distress and sleep disturbance. The aim of this study was to evaluate the relationship between tinnitus and sleep quality. Materials and Methods: Eighty-one patients (42 females, 39 males) with subjective tinnitus lasting more than 6 months in the last 6 months were included. Tinnitus handicap index (THI), Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) questionnaires were used. Results: There was a moderate statistically significant positive correlation between THI and both PSQI (r=0.411; p=&lt;0.001) and ISI (r=0.436; p=0.003). As THI increased, PSQI and ISI increased. Conclusion: Evaluating sleep quality is important in treatment planning to control tinnitus and improve the quality of life in tinnitus patients. Keywords: Tinnitus; Sleep Quality; Questionnaire

Effects of Tobacco Use on the Macrostructure and Microstructure of Sleep in Patients with OSA.

Both tobacco use and obstructive apnea-hypopnea syndrome (OSA) can affect sleep, and it is speculated that tobacco use may further affect the sleep of those with OSA. Our primary objective is to clarify the associations between tobacco use and the macrostructure and microstructure of sleep in patients with OSA. This retrospective study encompasses a cohort of 1017 patients who were hospitalized between January 2020 and January 2023 for the investigation of sleep disorders. Rigorous inclusion criteria were applied, and all patients underwent a comprehensive polysomnography (PSG) assessment and completed a Pittsburgh Sleep Quality Index (PSQI) questionnaire. Patients with OSA who concurrently used tobacco exhibited markedly inferior sleep quality than those who did not. Notably, there was no association between the degree of tobacco dependence and sleep quality. Those with OSA who used tobacco demonstrated a significant prolongation of stage 1 light sleep and a reduction of deep sleep duration (N3). In this group, those who demonstrated poor sleep quality had more pronounced alterations in light sleep stages with prolonged N1 and shortened N2 stages. Our findings reveal a substantial reduction in sleep quality amongst OSA patients who also use tobacco, compared to those with OSA who do not use tobacco. The rate of poor sleep quality was not linearly associated with the level of tobacco dependence. Tobacco use was associated with alterations in both light and slow wave sleep in those with OSA. Importantly, the effects of tobacco dependence on sleep structure were more pronounced in those with more severe OSA.

Evaluation of the influence of sleep on obesity indices among young adults

Background: Sleep is an indispensable physiological process. The recommended average sleep duration for young adults is about 7–9 h a day. Quality and duration of sleep have a considerable influence on several anthropometric measurements, in addition to the typical determinants, such as level of physical activity, dietary choices, and genetic predisposition. These days, obesity is a ubiquitous public health crisis and there has been a parallel rise in sleep deprivation. Several reviews have suggested an increased likelihood of obesity among short-sleepers. Aims and Objectives: This study aims to assess the quality and duration of sleep, physical activity, and obesity indices in young adults and evaluate the impact of sleep on the obesity indices. Materials and Methods: Three hundred young adults of both sexes aged between 18 and 25 years were selected and their anthropometric measurements such as height, weight, waist, and hip circumference were recorded. Obesity indices – waist/hip ratio (WHR), waist to height ratio, body mass index (BMI), abdominal volume index (AVI), and conicity index were calculated. Pittsburgh Sleep Quality Index (PSQI) and General Practice Physical Activity Questionnaire were used to assess the quality and duration of sleep as well as physical activity, respectively. Based on the PSQI index, they were categorized into – Group 1 with adequate sleep and Group 2 without adequate sleep. Independent Student’s t-test was employed; P &lt; 0.05 was considered significant. Results: Analysis of anthropometric measurements showed a significant increase in weight (63.60 ± 16.52 kg vs. 60.26 ± 13.73 kg), waist circumference (79.52 ± 12.83 cm vs. 78.60 ± 10.27 cm), and AVI (13.07 ± 4.20 vs. 12.68 ± 3.30) in Group 2. BMI and WHR were increased in Group 2 but were not statistically significant. Physical activity was found to be more in Group 2 subjects. Conclusion: Quality of sleep has a role in obesity irrespective of physical activity.

Sleep disorders among South Indian computer professionals and the beneficial effect of blue light filters

Background: Prolonged exposure to light emitted from screen-based devices has been known to cause sleep disturbances. Although computer professionals have high screen exposure and screen exposure is known to cause sleep disturbances, there is no published literature on sleep disorders among computer professionals. Aims and Objectives: To find out the prevalence of sleep disorders among computer professionals in South India and their association with risk factors like screen time and duration of work. Material and Methods: Data were collected online from computer professionals working in South India using a structured questionnaire in Google Forms. The form contained questions on demographics, medical history, and the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Data were entered in Microsoft Excel and analyzed using SPSS 17. The chi-square test, odds ratio, Kruskal–Wallis test, and regression analyses were used. Results: The prevalence of sleep disorders among computer professionals in South India was found to be 63.3%. Sleep latency was found to be the most significant contributor to the total PSQI score. Significantly associated risk factors were daily and weekly work duration and daily screen time. Working for more than 8 h a day was found to be the single independent risk factor for 7.9% of those with sleep disorders. Using a blue-light filter was found to be protective. Conclusion: There is a high prevalence of sleep disorders among computer professionals. Interventions like monitoring the daily duration of screen exposure and total daily work hours and periodic evaluation of the sleep health of computer professionals are crucial to reducing morbidity and early mortality.

ANALYSIS OF PHYSIOLOGICAL ERGONOMICS FOR NIGHT SHIFT WORKERS CORRELATED WITH SLEEP QUALITY AND TIME TO RECOVERY

The worker’s recovery time from physical and mental workload is a crucial factor for office and factory management and it will effect on the working performance and design working system. The aim of this paper is to investigate the impact of physiological conditions on sleep quality and time to recovery for night shift electric steam power plant workers. The research is started with study literatures on physiology ergonomics, sleep quality measurement, human metabolism, expenditure energy graph and physical/mental workload. The research worked with 50 samples (age between 30 to 45 years old) who have duty to control the electric steam power plant on dynamic computer screen in the night shift. The Pittsburgh Sleep Quality Index (PSQI) questionnaire was used subjectively to measure the value of sleep quality on 19 self – rated questions that assessed various sleep quality – related factor over the previous month. To know the speed of Time to Recovery (TTR), every worker perform a treadmill load with constant speed of 5 Km/hour for 10 minutes. Heart rate changes before activity, during activity (treatment) and TTR are recorded and it be analysed the pattern of relationship conducting to PSQI score. According to the data analysis, the higher PSQI score the longer time consume by workers to recovery. Moreover, Pearson statistic test results found that there is a strong relationship between sleep quality (PSQI value) and TTR for workers with value of 0.853. In sort, improving the quality of sleep for night shift electric steam power plant workers can definitely improve work performance on a shorter rest time or healthier conditions of workers.

Association of dietary acid-base load with psychological disorders, sleep and circadian rhythm among obese and overweight women: a cross-sectional study

Background: Epidemiological studies have reported that dietary acid load is associated with psychological disorders through different pathways. We aimed to examine the association of dietary acid-base load with psychological disorders, sleep and circadian rhythm. Methods: This study was performed on 404 female subjects aged 18 years and above. We evaluated potential renal acid load (PRAL) and net endogenous acid production (NEAP) score by a validated food frequency questionnaire (FFQ) for Iran which contained 147 items. To assess psychological disorders, an Iranian validated version of the depression, anxiety and stress scale (DASS-21) was used. The Pittsburgh Sleep Quality Index (PSQI) and morning-evening questionnaire (MEQ) were applied to evaluate sleep quality and circadian rhythm status, respectively. Results: After adjustment for a wide range of confounding variables, a significant positive association was observed between dietary acid-base load and severe depression (ORPRAL=1.10, 95% CI=1.01-1.19, p=0.02 and ORNEAP=2.46, 95% CI=1.41-14.61, p=0.02). Women in the high dietary acid base load category had higher anxiety (ORPRAL=1.12, 95% CI=1.02-1.23, p=0.01 and ORNEAP=1.80,95% CI=1.12-10.72, p=0.01). There was a strong positive relationship between dietary acid-base load and sleep disturbance (p&lt;0.05). Additionally, circadian rhythm assessment showed that those with greater commitment to PRAL had 23% higher risk of being completely evening type, while the odds of being completely morning type were decreased by 15% and 12% across higher adherence to PRAL and NEAP. Conclusion: Women with higher dietary acid-base load score had greater odds for depression, anxiety, psychological distress, sleep disturbance and evening-type circadian rhythm compared to lower ones.

PENGARUH ACUPRESSURE TITIK HT7 SHENMEN TERHADAP LATENSI DAN DURASI TIDUR PASIEN KANKER PASCA TERAPI

Abstract: Disruption of sleep latency and duration of cancer patients occurs due to multifactorial causes, one of which is a side effect of cancer therapy. The aim of this study was to analyze the effect of acupressure at the Shenmen HT7 point on sleep latency and duration of post-therapy cancer patients. The design uses a pre-experimental one-group pretest-posttest design approach. The population is 50 cancer patients at the Pucang Sewu Health Center and the Rangkah Health Center, Surabaya. A sample of 25 respondents was taken by purposive sampling according to the researcher's criteria. The instrument used was the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The results of the pre-test mean latency and sleep duration scores respectively were 1.96 + 0.61 and 1.08 + 0.86, while in the post-test conditions it was 1.12 + 0.72 and 0.56 + 0.71. The results of the Wilcoxon Signed Rank Test statistical test found that the p-value on the latency and sleep duration variables was 0.000 and 0.001, respectively, which means that there was a significant effect of giving the HT7 Shenmen point acupressure on the latency and sleep duration of post-therapy cancer patients. HT7 Shenmen stimulates the release of endorphins which cause relaxation, a feeling of calm, comfort, thereby helping to improve sleep latency and duration.

Sleep deprivation alters pubertal timing in humans and rats: the role of the gut microbiome.

Evidence implied that sleeping duration is associated with the timing of puberty and that sleep deprivation triggers early pubertal onset in adolescents. Sleep deprivation can affect metabolic changes and gut microbiota composition. This study investigated the effects of sleep deprivation on pubertal onset and gut microbiota composition in animal models and a human cohort. This study comprised 459 boys and 959 girls from the Taiwan Pubertal Longitudinal Study. Sleep duration was evaluated using the self-report Pittsburgh Sleep Quality Index questionnaire. Early sexual maturation was defined by pediatric endocrinologist assessments. Mediation analyses were done to examine the association between sleep parameters, obesity, and early sexual maturation. Besides, Sprague Dawley juvenile rats were exposed to 4 weeks of chronic sleep deprivation. Vaginal opening (VO) and preputial separation (PS) were observed every morning to determine pubertal onset in female and male rats. The sleep-deprived juvenile rats in the sleep-deprived-female (SDF) and sleep-deprived-male (SDM) groups experienced delayed VO (mean VO days: 33 days in control; 35 days in SDF; p-value < 0.05) and PS (mean PS days: 42 days in control; 45 days in SDM; p-value < 0.05), respectively. Relative to their non-sleep-deprived counterparts, the sleep-deprived juvenile rats exhibited lower body weight and body fat percentage. Significant differences in relative bacterial abundance at genus levels and decreased fecal short-chain-fatty-acid levels were identified in both the SDF and SDM groups. In the human cohort, insufficient sleep increased the risk of early sexual maturation, particularly in girls (OR, 1.44; 95% CI: 1.09 to 1.89; p-value < 0.01). Insufficient sleep also indirectly affected early sexual maturation in girls, with obesity serving as the mediator. Overall, sleep deprivation altered the timing of puberty in both animal and human models but in different directions. In the rat model, sleep deprivation delayed the pubertal onset in juvenile rats through gut dysbiosis and metabolic changes, leading to a low body weight and body fat percentage. In the human model, sleep deprivation led to fat accumulation, causing obesity in girls, which increased the risk of early puberty.

Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study

ObjectivePoor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined...

Reasons behind Sleep Deprivation among Adolescents: Evidence from Beijing

Although current studies have examined the association between multiple variables and sleep deprivation among adolescents, such as the use of electronic devices and stress, few studies managed to disassociate the variables and examine the impact of each one on sleep individually. The objective of this study is to examine which factor between the use of electronic devices, workload, stress and basic psychological needs of an individual has the most impact on sleep duration and quality of adolescents. 16 participants volunteered for this research measuring their sleep and deep sleep through commercially available smart band provided. They self-reported the sleep data recorded along with the amount of time spent on electronic devices and schoolwork, and a rating of workload and stress on a scale of 1-10 through a period of 38 days. Participants then completed a Pittsburgh Sleep Quality Index questionnaire and a Self-Determination Theory questionnaire. Results show that stress has the most impact on both sleep duration and quality. The fulfillment of an individual’s psychological needs highly correlates with sleep: the unmet psychological needs directly influence other variables such as stress level which will affect sleep. This research shows inconsistency during data analysis when different method is applied potentially due to time constrain of this research, future research is needed to prove the validity of the finding.

Memory performance mediates subjective sleep quality associations with cerebrospinal fluid Alzheimer's disease biomarker levels and hippocampal volume among individuals with mild cognitive symptoms.

Sleep disturbances are prevalent in Alzheimer's disease (AD), affecting individuals during its early stages. We investigated associations between subjective sleep measures and cerebrospinal fluid (CSF) biomarkers of AD in adults with mild cognitive symptoms from the European Prevention of Alzheimer's Dementia Longitudinal Cohort Study, considering the influence of memory performance. A total of 442 participants aged >50 years with a Clinical Dementia Rating (CDR) score of 0.5 completed the Pittsburgh Sleep Quality Index questionnaire and underwent neuropsychological assessment, magnetic resonance imaging acquisition, and CSF sampling. We analysed the relationship of sleep quality with CSF AD biomarkers and cognitive performance in separated multivariate linear regression models, adjusting for covariates. Poorer cross-sectional sleep quality was associated with lower CSF levels of phosphorylated tau and total tau alongside better immediate and delayed memory performance. After adjustment for delayed memory scores, associations between CSF biomarkers and sleep quality became non-significant, and further analysis revealed that memory performance mediated this relationship. In post hoc analyses, poorer subjective sleep quality was associated with lesser hippocampal atrophy, with memory performance also mediating this association. In conclusion, worse subjective sleep quality is associated with less altered AD biomarkers in adults with mild cognitive symptoms (CDR score 0.5). These results could be explained by a systematic recall bias affecting subjective sleep assessment in individuals with incipient memory impairment. Caution should therefore be exercised when interpreting subjective sleep quality measures in memory-impaired populations, emphasising the importance of complementing subjective measures with objective assessments.