Pitch Factor Research Articles

Visualization of X-ray fields, overlaps, and over-beaming on surface of the head in spiral computed tomography using computer-aided design-based X-ray beam modeling.

To visualize the X-ray fields, overlaps, and over-beaming on the skin surface during spiral head CT scanning. The measured pitch factors were determined by measuring 3 rotation times, 11 table-feed speeds, and an X-ray beam width. The X-ray fields, overlaps, and over-beaming on the skin surface were calculated via computer-aided design-based X-ray beam modeling, and the values obtained using the nominal pitch and measured pitch factors were compared. The X-ray fields with measured pitch factors exceeded those with nominal pitch factors. The overlaps increased with a decrease in the nominal pitch and measured pitch factors and were observed even at a nominal pitch factor of 1.0. The most stretched over-beaming field was observed with the measured pitch factor of 0.670. The technique can show the overlaps of the X-ray fields and may determine the adequate start angle to prevent overlaps to the eye lens.

An investigation on NGR failure in Indian smart cities while replacing the existing overhead lines by underground cables

Abstract Nowadays, Indian power distribution companies (PDCs) are implementing smart distribution networks. Older cities are becoming smarter as per the recent government’s policy. Existing overhead distribution lines are being replaced by underground cables as an essential criterion of a smart city. One of the main problems arising in this process is the overheating of the neutral grounding resistor (NGR) in 11 kV distribution systems, even in normal conditions. NGRs, placed inside the substations, are overloading the air conditioning and exhaust systems of the substation. Sometimes failure of the NGR occurs due to overheating. In this paper, a comprehensive investigation has been carried out to reach the roots of this problem. It is observed that long underground cables have a higher ground capacitance than overhead distribution lines. Due to the higher cable capacitance, the third harmonic current circulates through neutral, which overheats the NGR even in normal conditions. The situation becomes worse when the substation runs on diesel generators (DGs) in an isolated state under main grid failure, as a higher amount of third-harmonic current circulates depending on the type of winding and pitch factor of the DGs. Different solutions are proposed, and their advantages and disadvantages are analyzed. Finally, the rating of the NGR is modified, and louvers-cooling fan arrangement is preferred for the running substation.

Performance enhancement of frequency-doubling gyroklystron amplifier by magnetic field tapering

A uniform magnetic field across the device is often used to analyze gyroklystron. In this paper, a tapered magnetic field is applied across the two-cavity 35 GHz frequency-doubling gyroklystron to improve its performance. Device performance is compared between tapered and uniform magnetic field cases using particle-in-cell code “CST.” The result confirms that the tapered magnetic field significantly improves the device performance parameters such as output power, efficiency, gain, and bandwidth compared to uniform magnetic field conditions. With a 1.6-kW driver power, 306 kW RF output power along with 22.8 dB gain is achieved for a tapered magnetic field case, while 227 kW RF output power along with 21.5 dB gain is achieved for a uniform magnetic field case. When the magnetic field is uniform, the efficiency and bandwidth of a gyroklystron are approximately 21.6% and 100 MHz, respectively; however, for the tapered magnetic field, it can rise to 29.1% and 120 MHz, respectively. Device efficiency results suggest that a tapered magnetic field improves energy transfer from the electron beam to the RF field. A parametric study for both magnetic field cases examines the effect of magnetic field strength, beam current, beam voltage, and pitch factor on the device. This detailed research recommends optimizing frequency-doubling gyroklystron performance with tapered magnetic fields.

Dosiomics-based detection of dose distribution variations in helical tomotherapy for prostate cancer patients: influence of treatment plan parameters.

The stability of dosiomics features (DFs) and dose-volume histogram (DVH) parameters for detecting disparities in helical tomotherapy planned dose distributions was assessed. Treatment plans of 18 prostate patients were recalculated using the followings: field width (WF) (2.5 vs. 5), pitch factor (PF) (0.433 vs. 0.444), and modulation factor (MF) (2.5 vs. 3). From each of the eight plans per patient, ninety-three original and 744 wavelet-based DFs were extracted, using 3D-Slicer software, across six regions including: target volume (PTV), pelvic lymph nodes (PTV-LN), PTV + PTV-LN (PTV-All), one cm rind around PTV-All (PTV-Ring), rectum, and bladder. For the resulting DFs and DVH parameters, the coefficient of variation (CV) was calculated, and using hierarchical clustering, the features were classified into low/high variability. The significance of parameters on instability was analyzed by a three-way analysis of variance. All DF's were stable in PTV, PTV-LN, and PTV-Ring (average CV ( ≤0.36). Only one feature in the bladder ( =0.9), rectum ( =0.4), and PTV-All ( =0.37) were considered unstable due to change in MF in the bladder and WF in the PTV-All. The value of for the wavelet features was much higher than that for the original features. Out of 225 unstable wavelet features, 84 features had ≥1. The CVs for all the DVHs remained very small ( <0.06). This study highlights that the sensitivity of DFs to changes in tomotherapy planning parameters is influenced by the region and the DFs, particularly wavelet features, surpassing the effectiveness of DVHs.

Task-based assessment for radiation dose optimization in CT abdominal examinations: A phantom study

Recent advancements in Computed Tomography (CT) imaging technology have significantly enhanced healthcare delivery. However, public concern regarding the safety and health risks associated with increased exposure to ionizing radiation has escalated. In response, this study performs a quantitative analysis comparing the image quality of the standard CT abdomen protocol (P1 protocols) with alternative optimization techniques. Adjustments to standard CT scan parameters, including tube potential (P2 protocols), effective mAs value (P3), and pitch factor (P4, P5, P6 protocols), were made to evaluate the effectiveness of these optimization strategies. A 64-slice CT scanner (Canon, Japan) and a polymethylmethacrylate (PMMA) textural water phantom was utilized in this study. CT dose descriptors, volume weighted CT Dose Index (CTDIvol) and dose-length product (DLP) alongside evaluation parameters such as Hounsfield Unit (HU) number, noise levels, Signal-to-Noise Ratio (SNR), and Contrast-to-Noise Ratio (CNR) were measured and analysed. Furthermore, this research introduced a Figure of Merit (FOM) based on the ratio of image quality parameters (SNR and CNR) to the CTDIvol, establishing a quantitative measure for optimization. A notable reduction in radiation dose—34.85% below the standard protocol (P1)—was observed in protocol P6, attributed to an increased pitch factor. Conversely, increase the effective mAs value has improved SNR and CNR values. The findings reveal that protocols P1 and P2 deliver the highest FOM for soft tissue and fat imaging, respectively. Protocol P1, with its higher attenuation factor, is optimal for abdominal examinations targeting soft tissues. Meanwhile, protocol P2's increase effective mAs value enhances beam intensity, improving CT numbers for fat tissues with their high-density composition. The study also found a strong correlation between FOM based on SNR and CNR values. In conclusion, adjustments to primary CT parameters significantly influence image quality. The FOM serves as an effective tool for measuring the overall performance of image quality, facilitating post-optimization assessment and contributing to the development of safer, more efficient CT imaging protocols.

Red and green inverted top-emitting quantum dot light-emitting diodes using CMOS-based electrodes for microdisplay applications

Silicon (Si) substrates and complementary metal-oxide-semiconductor (CMOS) technology are being used in microdisplays in augmented reality/virtual reality devices owing to higher pixel resolution. Quantum-dot light-emitting diodes (QLEDs) incorporating colloidal quantum dots have emerged as promising devices for display applications owing to their exceptional color, high luminance, and solution processibility. However, studies on QLEDs on Si, particularly for microdisplay applications, remain limited. This study investigated the device characteristics of inverted top-emitting QLEDs using Si substrates and various CMOS process-based electrode materials (aluminum (Al), Al/titanium nitride (TiN), titanium, cobalt, and tungsten) for microdisplay applications. Devices incorporating a thin TiN layer on an Al electrode exhibited the highest efficiency and luminance compared to those with other electrodes. We successfully fabricated red and green inverted top-emitting QLEDs using microdisplay pixel-structured Al/TiN electrodes, with pixel pitch and fill factor of 10.8 μm × 3.6 μm and 72.5 %, respectively. Further, the device efficiency was optimized by changing hole and electron transport layer thicknesses, resulting in different efficiencies and electroluminescence spectra owing to the microcavity effect. Optical simulations demonstrated consistency with the measured values. Thus, the selection of the bottom electrode and a suitable design that considers the microcavity effect are crucial for high-performance QLED-based microdisplays.

Influence of helical pitch and gantry rotation time on image quality and file size in ultrahigh-resolution photon-counting detector CT

The goal of this experimental study was to quantify the influence of helical pitch and gantry rotation time on image quality and file size in ultrahigh-resolution photon-counting CT (UHR-PCCT). Cervical and lumbar spine, pelvis, and upper legs of two fresh-frozen cadaveric specimens were subjected to nine dose-matched UHR-PCCT scan protocols employing a collimation of 120 × 0.2 mm with varying pitch (0.3/1.0/1.2) and rotation time (0.25/0.5/1.0 s). Image quality was analyzed independently by five radiologists and further substantiated by placing normed regions of interest to record mean signal attenuation and noise. Effective mAs, CT dose index (CTDIvol), size-specific dose estimate (SSDE), scan duration, and raw data file size were compared. Regardless of anatomical region, no significant difference was ascertained for CTDIvol (p ≥ 0.204) and SSDE (p ≥ 0.240) among protocols. While exam duration differed substantially (all p ≤ 0.016), the lowest scan time was recorded for high-pitch protocols (4.3 ± 1.0 s) and the highest for low-pitch protocols (43.6 ± 15.4 s). The combination of high helical pitch and short gantry rotation times produced the lowest perceived image quality (intraclass correlation coefficient 0.866; 95% confidence interval 0.807–0.910; p < 0.001) and highest noise. Raw data size increased with acquisition time (15.4 ± 5.0 to 235.0 ± 83.5 GByte; p ≤ 0.013). Rotation time and pitch factor have considerable influence on image quality in UHR-PCCT and must therefore be chosen deliberately for different musculoskeletal imaging tasks. In examinations with long acquisition times, raw data size increases considerably, consequently limiting clinical applicability for larger scan volumes.

Innovative Approaches to Wear Reduction in Horizontal Powder Screw Conveyors: A Design of Experiments-Guided Numerical Study

Numerical simulations play a vital role in the modern engineering industry, especially when faced with interconnected challenges such as particle interactions and the structural integrity of conveyor systems. This article focuses on the handling of materials and emphasizes the importance of using parametric numerical analysis to improve efficiency, reduce wear, and enhance the structural integrity of horizontal screw conveyors. Through the utilization of the Design of Experiments, we systematically investigated critical parameters such as screw pitch, clearance, wear, rotational velocity, and additional structural factors. This examination was carried out within a well-defined parametric framework, utilizing a combination of software tools provided by the Ansys suite and Minitab. The findings demonstrate the effectiveness of the Design of Experiments analysis in achieving improved performance and provide valuable insights for engineers and researchers involved in the design of conveyor systems. Furthermore, this comprehensive approach clarifies how conveyor systems respond to changes in parameters and highlights the complex interaction between transported particles and the conveyor system. We present a detailed analysis that clarifies the complex relationships and dependencies among different parameters, providing engineers and researchers with valuable insights. By understanding the interactions of these factors, the methodology provides not only results but also a strategic framework for advancing conveyor system design and engineering practices.

Assessment of temporal resolution and detectability of moving objects in CT: A task-based image quality study

The metrics used for assessing image quality in computed tomography (CT) do not integrate the influence of temporal resolution. A shortcoming in the assessment of image quality for imaging protocols where motion blur can therefore occur. We developed a method to calculate the temporal resolution of standard CT protocols and introduced a specific spatiotemporal formulation of the non-prewhitening with eye filter (NPWE) model observer to assess the detectability of moving objects as a function of their speed. We scanned a cubic water phantom with a plexiglass cylindrical insert (120 HU) using a large panel of acquisition parameters (rotation times, pitch factors and collimation widths) on two systems (GE Revolution Apex and Siemens SOMATOM Force) to determine the in-plane task-based transfer functions (TTF) and noise power spectra (NPS). The phantom set in a uniform rectilinear motion in the transverse plane allowed the temporal modulation transfer function (MTF) calculation. The temporal MTF appropriately compared the temporal resolution of the various acquisition protocols. The longitudinal TTF was measured using a thin tungsten wire. The detectability index showed the advantage of applying high rotation speed, wide collimations and high pitch for object detection in the presence of motion. No counterpart to the increase in these three parameters was found in the in-plane and longitudinal image quality.

Nonadiabatic effects in the electron-optical system of a relativistic millimeter-wave gyrotron

Gyrotrons based on relativistic electron flows generated by thermionic magnetron injection guns are promising pulsed sources of millimeter and submillimeter radiation with multi-megawatt output power. Obviously, to increase the output power of such devices, it is necessary to provide a high beam current of more than 100 A. At the selected emission density, this forces the use of an emitter with a sufficiently large area. As is well known, wide emitters produce beams with a large velocity spread, which reduces the efficiency of the electron-wave interaction. Therefore, it is necessary to increase the diameter and, accordingly, increase the distance from the cathode to the gyrotron cavity, which leads to an increase in the magnetization reversal coefficient. Thus, the magnetic field in the region of beam formation becomes weak, and the Larmor radius and the turn pitch of the electron trajectory become large compared to the geometry of the surrounding electrodes, which can cause nonadiabatic effects. In this work, we consider one of these effects, which consists in the emergence of a range of anode voltage values in which the monotonic growth of the pitch factor stops. The results of trajectory analysis using current tube and discrete source methods based on the ANGEL software package are presented, as well as an assessment of the influence of a magnetic lens on the properties of an electron beam based on a simple analytical model.

Optimization of the "Perth CT" Protocol for Preoperative Planning and Postoperative Evaluation in Total Knee Arthroplasty.

Background and Objectives: Total knee arthroplasty (TKA) has become the treatment of choice for advanced osteoarthritis. The aim of this paper was to show the possibilities of optimizing the Perth CT protocol, which is highly effective for preoperative planning and postoperative assessment of alignment. Materials and Methods: The cross-sectional study comprised 16 patients for preoperative planning or postoperative evaluation of TKA. All patients were examined with the standard and optimized Perth CT protocol using advance techniques, including automatic exposure control (AEC), iterative image reconstruction (IR), as well as a single-energy projection-based metal artifact reduction algorithm for eliminating prosthesis artifacts. The effective radiation dose (E) was determined based on the dose report. Imaging quality is determined according to subjective and objective (values of signal to noise ratio (SdNR) and figure of merit (FOM)) criteria. Results: The effective radiation dose with the optimized protocol was significantly lower compared to the standard protocol (p < 0.001), while in patients with the knee prosthesis, E increased significantly less with the optimized protocol compared to the standard protocol. No significant difference was observed in the subjective evaluation of image quality between protocols (p > 0.05). Analyzing the objective criteria for image quality optimized protocols resulted in lower SdNR values and higher FOM values. No significant difference of image quality was determined using the SdNR and FOM as per the specified protocols and parts of extremities, and for the presence of prothesis. Conclusions: Retrospecting the ALARA ('As Low As Reasonably Achievable') principles, it is possible to optimize the Perth CT protocol by reducing the kV and mAs values and by changing the collimation and increasing the pitch factor. Advanced IR techniques were used in both protocols, and AEC was used in the optimized protocol. The effective dose of radiation can be reduced five times, and the image quality will be satisfactory.

The Influence of the Presence or Absence of a Patient Transfer Slide Board on Radiation and Image Quality When Using an Automatic Tube Current Modulation with Bed Height Compensation

The purpose of this study was to evaluate the effect of patient transfer slide boards with automatic couch height positioning compensation (AHC) on image quality and radiation dose during computed tomography (CT) examinations. The chest phantom for Kyoto Kagaku (Kyoto) Type PBU-SS 2 was performed helical scan using a Canon Medical Systems (Tochigi) 80-row CT Aquilion Prime SP/i Edition. Scan parameters were tube voltage: 120 kV, tube current: min 50 mA max 500 mA with AHC for noise index: 15, slice thickness: 5.0 mm, rotation time: 0.35 s/rotation, pitch factor: 0.813, reconstruction kernel: FC03. Filtered back projection was used for image reconstruction. We compared the image noise and volume computed tomography dose index (CTDIvol) displayed on the console with and without the patient transfer slide boards by using or not using the AHC. When using the AHC, CTDIvol was increased (p<0.05), and image noise was decreased (p<0.05). Without the AHC, there was no significant difference in CTDIvol (p=0.11) and image noise (p=0.29). The slide board utilized in this experiment did not have a notable impact on either image quality or exposure dose. Nonetheless, the use of the slide board was found to result in excessive exposure during CT scans that employed AHC.

Helical Electron Beam Status Online Evaluation for Magnetron Injection Gun

The magnetron injection gun (MIG) is an essential component of the gyrotron traveling wave tube (gyro-TWT). Although the electron beam status influences the performance of the device, it cannot be measured directly in the experiment. An online evaluation module (OEM) for the experiment is developed to calculate the instant beam parameters of MIG. The OEM, by reconstructing the geometry of the MIG and related magnetic field distribution, can obtain the electron beam status under the operating parameters through the online simulation. The beam velocity spread of thermal emission with instant temperature and surface roughness are also considered. The validation is done in a W-band gyro-TWT, and the beam performance is evaluated in the experiment. With a pitch factor of 1.06 electron beam, the velocity spread affected by the electric-magnetic mismatch, thermal emission, and roughness is 1.00%, 0.56%, and 0.43%, respectively. The other beam parameters are also presented in the developed module. The OEM could guide and accelerate the testing process and ensure the safe and stable operation of the device.

Lifetime Attributable Breast Cancer Risk Related to Lung CT Scan in Women with Covid19

Abstract&#x0D; Purpose: Organ, effective dose, and Lifetime Attributable Risk (LAR) of breast cancer incidence related to lung Computed Tomography (CT) scans were evaluated. Seven hundred thirty-five female patients (20-50 years old) with Coronavirus (COVID-19) in four medical imaging centers in Tehran, Iran, were surveyed. Patients’ data, including age, sex, and exposure information (Kilovoltage (KVp), milliampere-second (mAs), pitch factor, Computed Tomography Dose Index (CTDIvol), and Dose Length Product (DLP)) were extracted from dose report pages in picture archiving and communication systems (PACS).&#x0D; Materials and Methods: Patients were divided into six age groups of 20-25, 25-30, 30-35, 35–40, 40-45, and 45–50 years. Breast, thyroid, lung, and heart absorbed doses, and also effective doses, were calculated by National Cancer Institute (NCICT) software, and LAR of breast cancer incidence has been evaluated by the Biological Effect of Ionizing Radiation (BEIR) VII in phase 2 report.&#x0D; Results: The average doses of breast, thyroid, lung, the heart were 3.97, 4.75, 4.10, and 3.37 mGy, respectively. Also, the average effective dose was 2.56 mSv. The average LAR of breast cancer in female patients was 7.45 per 100,000 exposures, decreasing dramatically with age. It was clear that exposure parameters and organ absorbed dose were significantly different between medical imaging centers (P value&lt;0.05).&#x0D; Conclusion: Although the CT scan is a useful instrument in the diagnosis of Corona disease, it should be suggested with caution due to the increased risk of breast cancer, especially in younger women and pediatrics. Also, low-dose CT scan protocols are recommended to minimize radiation effective and absorbed doses.

Optical concentration in fully delineated mid-wave infrared T2SL detectors arrays

The dependence of quantum efficiency (QE) on fill factor and pixel pitch is studied theoretically and experimentally in fully delineated type-II superlattice (T2SL) detectors. Theoretically, a 2-dimensional simulation model is used to compute the absorption in the array geometry, which shows an insensitivity of the optical response to the fill factor. This is a result of the photodiode array (PDA) geometry concentrating the light in the pixel area. QE measurements on PDAs with varying pixel pitch (from 225 to 10 μm) and fill factors (from 98% to 64%) confirm this independence of the QE on the fill factor and results in a 50% increase in the photocurrent density in 10 μm pitch PDAs compared to 225 μm pitch PDAs. Furthermore, measurements of the dark current density vs pixel size revealed an absence of surface leakage in these PDAs, which, combined with the increased photocurrent density results in an improved signal-to-noise ratio when reducing the pitch in these T2SL detectors. Finally, this result resolves the QE-modulation transfer function trade-off, as the electrical isolation of the pixel is carried out without impacting the QE of the array.

Design and verification of a backward wave oscillation suppression circuit for the Ka-band gyrotron travelling-wave tube.

Backward wave oscillation seriously degrades the stability of gyrotron travelling-wave tubes (gyro-TWTs), especially during high average/continuous wave operation. To solve this problem, a selective mode suppression structure (SMSS) based on the mode coupling principle is proposed and applied in the nonlinear beam-wave interaction region to suppress the parasitic TE11 mode. It is capable of obtaining a high power and improving the tube stability. Simulation results demonstrate that the SMSS can raise the starting current from 10 to 18A and the starting pitch factor from 1.2 to 1.6. Based on this proposed circuit, a Ka-band TE01 mode gyro-TWT was designed, and the particle-in-cell simulation shows that it can achieve a saturated output power of over 150 kW from 29.7 to 31.7GHz with a velocity spread of 2.2%. For verification, a SMSS is manufactured and cold tested. The measurement of S-parameters reveals that it can effectively suppress the parasitic TE11 mode.

Aerodynamic analysis of a novel pitch control strategy and parameter combination for vertical axis wind turbines

The performance of a vertical axis wind turbine (VAWT) deteriorates at low tip speed ratios (TSR) and it is mainly characterized by flow separation and dynamic stall. Several mitigating techniques have been developed recently based on flow separation and dynamic stall research activities. One of such techniques is the use of blade pitch angle control, which shows very promising optimal performance in VAWTs. However, its adaptation for periodic variation of the angle of attack remains an important issue that needs to be addressed urgently. Therefore, this paper proposes a novel pitch control strategy based on the VAWT-shape pitch motion to achieve blade dynamic pitch with the rotational parameters (TSR and azimuth angle). The pitch scale factor (μ) is introduced to proportionally vary the angle of attack. High accuracy computational fluid dynamics (CFD) methods are used to simulate dynamic changes in pitch angle, flow field and vortex shedding vorticity, with the turbulence modelled using the SST k-ω model. The results show that a 146% increase in power coefficient can be achieved using a μ of 0.3 at TSR of 1.25. Additionally, the use of dual pitch scale factors (dpsf) in the windward and leeward regions causes intense transient torque fluctuations at 0° (360°) and 180° azimuths due to a breaking distance in pitch angular velocity at these azimuths. Adding a weight function into the fitting process of the dpsf pitch curve effectively minimize these fluctuations.

Assessment of effective dose and radiation-induced cancer risk in CT-KUB

Background and objectivesAmong the various imaging techniques employed for disorders related to the renal and urinary tract systems, computed tomography of kidneys, ureters, and bladder (CT-KUB) is considered the gold standard. The study evaluated effective dose and organ equivalent dose and estimated cancer risk for patients undergoing CT-KUB scans. MethodsScans of 110 patients (76 males, 31 females; mean age 45 years) were completed using a calibrated GE Light Speed 64-slice multi-slice CT (MSCT) scanner. CT exposure parameters were recorded, including tube current, pitch factor tube potential, volume CT dose index (CTDIvol) and dose-length product (DLP), and the National Cancer Institute dosimetry system for computed tomography (NCICT) was used to calculate the effective dose for each patient. Patient organ doses for colon, breast, stomach, bladder, prostate, and ovaries were calculated and converted to estimate cancer risk, based on the Biological Effects of Ionizing Radiation (BEIR) VII report. ResultsCTDIvol, DLP, and effective dose reported mean values of 9.9 mGy, 483.57 mGy cm, and 5.8 mSv, respectively. Lifetime cancer risk ranged from 0.01% to 0.08%, with a mean of 0.03% per 100,000 CT-KUB procedures. For younger individuals, the level of risk was higher for females than for males. While male patients are at higher risk than females for colon cancer, with close risk for both genders regarding stomach and bladder cancers. A statistically significant positive correlation was observed between effective dose and body mass index (p < 0.011, r > 0.4), AP diameter (p < 0.01, r > 0.4), and transfer diameter (p < 0.01, r > 0.5). ConclusionsAlthough the reported effective doses fall within the standard limits, there is significant potential to reduce the radiation dose for patients undergoing CT-KUB. Possible options include low dose protocols and ultrasonography, depending on patient characteristics and clinical condition. Appropriate education and training of radiologic technologists can help to ensure radiation dose optimization.

Photon-Counting Versus Energy-Integrating Detector CT Angiography of the Lower Extremity in a Human Cadaveric Model With Continuous Extracorporeal Perfusion.

Detailed visualization of the arterial runoff is mandatory for the assessment of peripheral arterial occlusive disease. This study aims to compare the performance of a first-generation photon-counting detector computed tomography (PCD-CT) to a third-generation energy-integrating detector CT (EID-CT). Computed tomography angiographies of 8 upper leg arterial runoffs were performed on human cadaveric models with continuous extracorporeal perfusion. For both PCD-CT and EID-CT, radiation dose-equivalent 120 kVp acquisition protocols (low-/medium-/high-dose: CTDI Vol = 3/5/10 mGy) were used. All scans were performed with standard collimation (PCD-CT: 144 × 0.4 mm; EID-CT: 96 × 0.6 mm), a pitch factor of 0.4, and a gantry rotation time of 1.0 second. Reformatting of data included the use of comparable vascular kernels (Bv 48/49), a slice thickness and increment of 1.0 mm, and a field of view of 150 × 150 mm. Eight radiologists evaluated image quality independently using a browser-based pairwise forced-choice comparison setup. Kendall concordance coefficient ( W ) was calculated to estimate interrater agreement. Signal-to-noise ratio and contrast-to-noise ratio (CNR) were compared based on 1-way analyses of variance and linear regression analysis. Low-dose PCD-CT achieved superior signal-to-noise ratio/CNR values compared with high-dose EID-CT ( P < 0.001). Linear regression analysis suggested that an EID-CT scan with a CTDI Vol of at least 15.5 mGy was required to match the CNR value of low-dose PCD-CT. Intraluminal contrast attenuation was higher in PCD-CT than EID-CT, irrespective of dose level (415.0 ± 31.9 HU vs 329.2 ± 29.4 HU; P < 0.001). Subjective image quality of low-dose PCD-CT was considered superior to high-dose EID-CT ( P < 0.001). Interrater agreement was high ( W = 0.989). Using cadaveric models with continuous extracorporeal perfusion allows for intraindividual image quality comparisons between PCD-CT and EID-CT on variable dose levels. With superior luminal contrast attenuation and denoising in angiographies of the peripheral arterial runoff, PCD-CT displayed potential for radiation saving of up to 83% compared with EID-CT.

Low-Dose Chest CT Protocols for Imaging COVID-19 Pneumonia: Technique Parameters and Radiation Dose.

Chest computed tomography (CT) plays a vital role in the early diagnosis, treatment, and follow-up of COVID-19 pneumonia during the pandemic. However, this raises concerns about excessive exposure to ionizing radiation. This study aimed to survey radiation doses in low-dose chest CT (LDCT) and ultra-low-dose chest CT (ULD) protocols used for imaging COVID-19 pneumonia relative to standard CT (STD) protocols so that the best possible practice and dose reduction techniques could be recommended. A total of 564 articles were identified by searching major scientific databases, including ISI Web of Science, Scopus, and PubMed. After evaluating the content and applying the inclusion criteria to technical factors and radiation dose metrics relevant to the LDCT protocols used for imaging COVID-19 patients, data from ten articles were extracted and analyzed. Technique factors that affect the application of LDCT and ULD are discussed, including tube current (mA), peak tube voltage (kVp), pitch factor, and iterative reconstruction (IR) algorithms. The CTDIvol values for the STD, LDCT, and ULD chest CT protocols ranged from 2.79-13.2 mGy, 0.90-4.40 mGy, and 0.20-0.28 mGy, respectively. The effective dose (ED) values for STD, LDCT, and ULD chest CT protocols ranged from 1.66-6.60 mSv, 0.50-0.80 mGy, and 0.39-0.64 mSv, respectively. Compared with the standard (STD), LDCT reduced the dose reduction by a factor of 2-4, whereas ULD reduced the dose reduction by a factor of 8-13. These dose reductions were achieved by applying scan parameters and techniques such as iterative reconstructions, ultra-long pitches, and fast spectral shaping with a tin filter. Using LDCT, the cumulative radiation dose of serial CT examinations during the acute period of COVID-19 may have been inferior or equivalent to that of conventional CT.