Slow Decay Phase Research Articles

Distribution and recovery phase of geomagnetic storms during solar cycles 23 and 24

Abstract Coronal mass ejections (CMEs) and Stream Interaction Regions (SIRs) are the main drivers of intense geomagnetic storms. We study the distribution of geomagnetic storms associated with different drivers during solar cycles 23 and 24 (1996-2019). Although the annual occurrence rate of geomagnetic storms in both cycles tracks the sunspot cycle, the second peak in storm activity lags the second sunspot peak. SIRs contribute significantly to the second peak in storm numbers in both cycles, particularly for moderate to stronger-than-moderate storms. We note semiannual peaks in storm numbers much closer to equinoxes for moderate storms, and slightly shifted from equinoxes for intense and stronger-than-intense storms. We note a significant fraction of multiple-peak storms in both cycles due to isolated ICMEs/SIRs, while single-peak storms from multiple interacting drivers, suggesting a complex relationship between storm steps and their drivers. Our study focuses on investigating the recovery phases of geomagnetic storms and examining their dependencies on various storm parameters. Multiple-peak storms in both cycles have recovery phase duration strongly influenced by slow and fast decay phases with no correlation with the main phase buildup rate and Dst peak. However, the recovery phase in single-peak storms for both cycles depends to some extent on the main phase buildup rate and Dst peak, in addition to slow and fast decay phases. Future research should explore recovery phases of single and multiple-peak storms incorporating in-situ solar wind observations for a deeper understanding of storm evolution and decay processes.

Flares, Rotation, and Planets of the AU Mic System from TESS Observations

Abstract AU Mic is a young (∼24 Myr), pre-main-sequence M dwarf star that was observed in the first month of science observations of the Transiting Exoplanet Survey Satellite (TESS) and reobserved 2 years later. This target has photometric variability from a variety of sources that is readily apparent in the TESS light curves; spots induce modulation in the light curve, flares are present throughout (manifesting as sharp rises with slow exponential decay phases), and transits of AU Mic b may be seen by eye as dips in the light curve. We present a combined analysis of both TESS Sector 1 and Sector 27 AU Mic light curves including the new 20 s cadence data from TESS Year 3. We compare flare rates between both observations and analyze the spot evolution, showing that the activity levels increase slightly from Sector 1 to Sector 27. Furthermore, the 20 s data collection allows us to detect more flares, smaller flares, and better resolve flare morphology in white light as compared to the 2 minute data collection mode. We also refine the parameters for AU Mic b by fitting three additional transits of AU Mic b from Sector 27 using a model that includes stellar activity. We show that the transits exhibit clear transit timing variations with an amplitude of ∼80 s. We also detect three transits of a 2.8 R ⊕ planet, AU Mic c, which has a period of 18.86 days.

Layer-dependent photoexcited carrier dynamics of WS2 observed using single pulse pump probe method

Understanding the ultrafast carrier dynamics and the mechanism of two-dimensional (2D) transition metal dichalcogenides (TMDs) is key to their applications in the field of optoelectronic devices. In this work, a single pulse pump probe method is introduced to detect the layer-dependent ultrafast carrier dynamics of monolayer and few-layer WS2 excited by a femtosecond pulse. Results show that the ultrafast carrier dynamics of the layered WS2 films can be divided into three stages: the fast photoexcitation phase with the characteristic time of 2–4 ps, the fast decay phase with the characteristic time of 4–20 ps, and the slow decay phase lasting several hundred picoseconds. Moreover, the layer dependency of the characteristic time of each stage has been observed, and the corresponding mechanism of free carrier dynamics has been discussed. It has been observed as well that the monolayer WS2 exhibits a unique rising time of carriers after photoexcitation. The proposed method can be expected to be an effective approach for studying the dynamics of the photoexcited carriers in 2D TMDs. Our results provide a comprehensive understanding of the photoexcited carrier dynamics of layered WS2, which is essential for its application in optoelectronics and photovoltaic devices.

Non-Invasive Functional Evaluation of the Human Spinal Cord by Assessing the Peri-Spinal Neurovascular Network With Near Infrared Spectroscopy.

Current medical care lacks an effective functional evaluation for the spinal cord. Magnetic resonance imaging and computed tomography mainly provide structural information of the spinal cord, while spinal somatosensory evoked potentials are limited by a low signal to noise ratio. We developed a non-invasive approach based on near-infrared spectroscopy in dual-wavelength (760 and 850 nm for deoxy- or oxyhemoglobin respectively) to record the neurovascular response (NVR) of the peri-spinal vascular network at the 7th cervical and 10th thoracic vertebral levels of the spinal cord, triggered by unilateral median nerve electrical stimulation (square pulse, 5-10 mA, 5 ms, 1 pulse every 4 minutes) at the wrist. Amplitude, rise-time, and duration of NVR were characterized in 20 healthy participants. A single, painless stimulus was able to elicit a high signal-to-noise ratio and multi-segmental NVR (mainly from Oxyhemoglobin) with a fast rise time of 6.18 [4.4-10.4] seconds (median [Percentile 25-75]) followed by a slow decay phase for about 30 seconds toward the baseline. Cervical NVR was earlier and larger than thoracic and no left/right asymmetry was detected. Stimulus intensity/NVR amplitude fitted to a 2nd order function. The characterization and feasibility of the peri-spinal NVR strongly support the potential clinical applications for a functional assessment of spinal cord lesions.

Richness and composition of macrofungi on large decaying trees in a Central European old-growth forest: a case study on silver fir (Abies alba)

The species richness and composition of macrofungi on huge fallen trunks of silver fir (Abies alba) were monitored during a case study in the well-preserved Boubinský prales virgin forest in Czechia. A detailed survey of all macrofungal groups recorded 200 species on 30 trunks within the diameter range of 85–190 cm. This number is very high in the overall context and includes many rare and threatened species. The species-richest groups were corticioids and fleshy saprotrophic fungi. Individual trunks were inhabited by 4–33 species. The species richness was negatively correlated with trunk decay and positively with bark cover, moss cover and trunk length. Simultaneously, it was negatively correlated with increasing time since tree fall, time since tree death and the way of fall, namely its category ‘broken’. Species composition was significantly influenced by decay, bark cover, moss cover, and, to a lesser degree, also by canopy cover, time since fall and time since death. The best trunks in terms of mycobiota rarity and nature conservation were those which died a long time ago but fell to the ground only recently. They have gone through a long phase of slow decay and gradual succession in standing position. As a result, they are inhabited by many distinctive fungi, especially those preferring natural forests. Durandiella gallica, Hohenbuehelia josserandii, Panellus violaceofulvus, Phellinus pouzarii and Pseudoplectania melaena can be considered almost exclusive fir specialists. All these fir-associated fungal species are immediately threatened by the gradual disappearance of firs resulting mainly from ungulate overpopulation, requiring the urgent implementation of appropriate conservation measures. A list of fungi characteristic of wood of silver fir and Norway spruce is presented.

On the Origin of Optical Radiation During the Impulsive Phase of Flares on dMe Stars. II. Continuum and Line Radiation

It is argued that not only the blue (at the brightness maximum) but also the red (in the slow decay phase) components of the optical continuum of powerful flares on dMe stars are formed near the photosphere. The possible appearance of HeI lines in the relaxation zones for the plasma to a state of thermal equilibrium (as a result of a rise in electron temperature owing to elastic collisions of electrons with atoms and ions) is noted (for sufficiently high speeds of a non-stationary chromospheric shock wave propagating toward the photosphere of the Sun and stars). A scheme is proposed for the positioning of the "layers" of plasma responsible for the generation of radiation in the white light continuum during the impulsive phase of powerful stellar flares.

The Erratic Path to Coalescence of LISA Massive Black Hole Binaries in Subparsec-resolution Simulations of Smooth Circumnuclear Gas Disks

Abstract We perform high-resolution simulations to follow the orbital decay of 5 × 105 and 107 M ⊙ massive black hole (MBH) pairs embedded in a circumnuclear gas disk (CND), from the CND scale (100 pc) down to 0.1–0.01 pc, the scale at which a circumbinary disk (CBD) could form. The MBHs’ erratic orbital evolution is characterized by three stages: (i) a slow initial decay that leads to some circularization; (ii) a fast-migration phase, analogous to type III migration for massive planets in protoplanetary disks, in which angular momentum is efficiently drained by disk-driven torques arising from the co-orbital region of the secondary MBH, at a distance of 1–3 Hill radii; and (iii) a very slow decay phase, in which orbital angular momentum can even increase. In this last stage, a CBD forms when the parsec-scale decay rate becomes small enough to allow sufficient time for a cavity to be carved. When this happens, the MBH separation nearly stalls in our higher-resolution run. We suggest an empirically modified gap-opening criterion that takes into account such timescale effects, as well as other deviations from standard assumptions. Interestingly, a CBD does not form in the lower-resolution runs, resulting in a faster subparsec decay. Our findings show that the subparsec MBH pairing in gaseous disks is a stochastic and fragile process. Additional mechanisms, such as the stellar-driven hardening, may be necessary to guarantee that the gravitational wave emission phase is entered and the MBHs become accessible to future detectors such as the Laser Interferometer Space Antenna.

Effect of oxygen concentration on the postdischarge decay of hydroxyl density in humid nitrogen-oxygen pulsed streamer discharge

In this study, the effect of oxygen (O2) concentration in the range of 0.000 1% (= 1 ppm) to 20% on the decay of hydroxyl (OH) density after pulsed streamer discharge is examined in a humid nitrogen-oxygen mixture under atmospheric pressure. The decay of OH density was measured using laser-induced fluorescence and compared with one-dimensional postdischarge simulations. The simulation results are consistent with the measured decay of OH density for all O2 concentrations. Essentially, the OH decay was double exponential, consisting of initial rapid decay for t < 0.1 ms and subsequent slow decay for t > 1 ms, where t represents the postdischarge time. In the slow decay phase, O2 change in the order of 10 ppm markedly affected the OH decay rate when O2 < 100 ppm. The sensitive effect of the small amount of O2 can be attributed to the reaction, , which converts H atoms to HO2, and the subsequent OH production via H+HO2→ OH+OH. Other production and loss processes of OH in the postdischarge phase were also examined.

Role of Intracellular Na+ in the Regulation of [Ca2+]i in the Rat Suprachiasmatic Nucleus Neurons.

Transmembrane Ca2+ influx is essential to the proper functioning of the central clock in the suprachiasmatic nucleus (SCN). In the rat SCN neurons, the clearance of somatic Ca2+ following depolarization-induced Ca2+ transients involves Ca2+ extrusion via Na+/Ca2+ exchanger (NCX) and mitochondrial Ca2+ buffering. Here we show an important role of intracellular Na+ in the regulation of [Ca2+]i in these neurons. The effect of Na+ loading on [Ca2+]i was determined with the Na+ ionophore monensin and the cardiac glycoside ouabain to block Na+/K+-ATPase (NKA). Ratiometric Na+ and Ca2+ imaging was used to measure the change in [Na+]i and [Ca2+]i, and cell-attached recordings to investigate the effects of monensin and ouabain on spontaneous firing. Our results show that in spite of opposite effects on spontaneous firing and basal [Ca2+], both monensin and ouabain induced Na+ loading, and increased the peak amplitude, slowed the fast decay rate, and enhanced the slow decay phase of 20 mM K+-evoked Ca2+ transients. Furthermore, both ouabain and monensin preferentially enhanced nimodipine-insensitive Ca2+ transients. Together, our results indicate that in the SCN neurons the NKA plays an important role in regulating [Ca2+]i, in particular, associated with nimodipine-insensitive Ca2+ channels.

Decaying turbulence and magnetic fields in galaxy clusters

Abstract We explore the decay of turbulence and magnetic fields generated by fluctuation dynamo action in the context of galaxy clusters where such a decaying phase can occur in the aftermath of a major merger event. Using idealized numerical simulations that start from a kinetically dominated regime we focus on the decay of the steady state rms velocity and the magnetic field for a wide range of conditions that include varying the compressibility of the flow, the forcing wavenumber, and the magnetic Prandtl number. Irrespective of the compressibility of the flow, both the rms velocity and the rms magnetic field decay as a power law in time. In the subsonic case we find that the exponent of the power law is consistent with the −3/5 scaling reported in previous studies. However, in the transonic regime both the rms velocity and the magnetic field initially undergo rapid decay with an ≈t−1.1 scaling with time. This is followed by a phase of slow decay where the decay of the rms velocity exhibits an ≈−3/5 scaling in time, while the rms magnetic field scales as ≈−5/7. Furthermore, analysis of the Faraday rotation measure (RM) reveals that the Faraday RM also decays as a power law in time ≈t−5/7; steeper than the ∼t−2/5 scaling obtained in previous simulations of magnetic field decay in subsonic turbulence. Apart from galaxy clusters, our work can have potential implications in the study of magnetic fields in elliptical galaxies.

MULTIWAVELENGTH OBSERVATIONS OF MASTER OT 075353.88+174907.6: A LIKELY SUPEROUTBURST OF A LONG PERIOD DWARF NOVA SYSTEM

MASTER OT 075353.88+174907.6 was a blue optical transient reported by the MASTER-Net project on 2017 Oct 31. We carried out multiwavelength followup observations of this source during its 2017 outburst using Swift and RATIR. The source was found to be ∼&gt;4.4 mag above its quiescent level during the peak of the outburst and the outburst lasted ∼&gt;19 days. Our observations suggest that it was a superoutburst of a long period U Geminorum type dwarf nova system. The spectral energy distribution during the initial slow decay phase of the outburst was consistent with a disk-dominated spectrum (with spectral indices Γ≈1.5–2.3). Afterwards, the UV flux decreased slowlier than the optical and the spectral energy distribution was very steep with indices Γ≈3.7±0.7. This slow UV decay may be the emission from a cooling white dwarf heated during the outburst. No X-ray emission was detected from the source since it is likely located at a large distance &gt;2.3 kpc.

Multiscale analysis of turbulence evolution in the density-stratified intracluster medium

The diffuse hot medium inside clusters of galaxies typically exhibits turbulent motions whose amplitude increases with radius, as revealed by cosmological hydrodynamical simulations. However, its physical origin remains unclear. It could either be due to an excess injection of turbulence at large radii, or faster turbulence dissipation at small radii. We investigate this by studying the time evolution of turbulence in the intracluster medium (ICM) after major mergers, using the Omega500 non-radiative hydrodynamical cosmological simulations. By applying a novel wavelet analysis to study the radial dependence of the ICM turbulence spectrum, we discover that faster turbulence dissipation in the inner high density regions leads to the increasing turbulence amplitude with radius. We also find that the ICM turbulence at all radii decays in two phases after a major merger: an early fast decay phase followed by a slow secular decay phase. The buoyancy effects resulting from the ICM density stratification becomes increasingly important during turbulence decay, as revealed by a decreasing turbulence Froude number $Fr \sim \mathcal{O}(1)$. Our results indicate that the stronger density stratification and smaller eddy turn-over time are the likely causes of the faster turbulence dissipation rate in the inner regions of the cluster.

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms.

Characterizing the contractile function of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) is key for advancing their utility for cellular disease models, promoting cell based heart repair, or developing novel pharmacological interventions targeting cardiac diseases. The aim of the present study was to understand whether steady-state and kinetic force parameters of β-myosin heavy chain (βMyHC) isoform-expressing myofibrils within human embryonic stem cell-derived cardiomyocytes (hESC-CMs) differentiated in vitro resemble those of human ventricular myofibrils (hvMFs) isolated from adult donor hearts. Contractile parameters were determined using the same micromechanical method and experimental conditions for both types of myofibrils. We identified isoforms and phosphorylation of main sarcomeric proteins involved in the modulation of force generation of both, chemically demembranated hESC-CMs (d-hESC-CMs) and hvMFs. Our results indicate that at saturating Ca2+ concentration, both human-derived contractile systems developed forces with similar rate constants (0.66 and 0.68 s−1), reaching maximum isometric force that was significantly smaller for d-hESC-CMs (42 kPa) than for hvMFs (94 kPa). At submaximal Ca2+-activation, where intact cardiomyocytes normally operate, contractile parameters of d-hESC-CMs and hvMFs exhibited differences. Ca2+ sensitivity of force was higher for d-hESC-CMs (pCa50 = 6.04) than for hvMFs (pCa50 = 5.80). At half-maximum activation, the rate constant for force redevelopment was significantly faster for d-hESC-CMs (0.51 s−1) than for hvMFs (0.28 s−1). During myofibril relaxation, kinetics of the slow force decay phase were significantly faster for d-hESC-CMs (0.26 s−1) than for hvMFs (0.21 s−1), while kinetics of the fast force decay were similar and ~20x faster. Protein analysis revealed that hESC-CMs had essentially no cardiac troponin-I, and partially non-ventricular isoforms of some other sarcomeric proteins, explaining the functional discrepancies. The sarcomeric protein isoform pattern of hESC-CMs had features of human cardiomyocytes at an early developmental stage. The study indicates that morphological and ultrastructural maturation of βMyHC isoform-expressing hESC-CMs is not necessarily accompanied by ventricular-like expression of all sarcomeric proteins. Our data suggest that hPSC-CMs could provide useful tools for investigating inherited cardiac diseases affecting contractile function during early developmental stages.

During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons

As neuronal development progresses, GABAergic synaptic transmission undergoes a defined program of reconfiguration. For example, GABAA receptor (GABAAR)-mediated synaptic currents, (miniature inhibitory postsynaptic currents; mIPSCs), which initially exhibit a relatively slow decay phase, become progressively reduced in duration, thereby supporting the temporal resolution required for mature network activity. Here we report that during postnatal development of cortical layer 2/3 pyramidal neurons, GABAAR-mediated phasic inhibition is influenced by a resident neurosteroid tone, which wanes in the second postnatal week, resulting in the brief phasic events characteristic of mature neuronal signalling. Treatment of cortical slices with the immediate precursor of 5α-pregnan-3α-ol-20-one (5α3α), the GABAAR-inactive 5α-dihydroprogesterone, (5α-DHP), greatly prolonged the mIPSCs of P20 pyramidal neurons, demonstrating these more mature neurons retain the capacity to synthesize GABAAR-active neurosteroids, but now lack the endogenous steroid substrate. Previously, such developmental plasticity of phasic inhibition was ascribed to the expression of synaptic GABAARs incorporating the α1 subunit. However, the duration of mIPSCs recorded from L2/3 cortical neurons derived from α1 subunit deleted mice, were similarly under the developmental influence of a neurosteroid tone. In addition to principal cells, synaptic GABAARs of L2/3 interneurons were modulated by native neurosteroids in a development-dependent manner. In summary, local neurosteroids influence synaptic transmission during a crucial period of cortical neurodevelopment, findings which may be of importance for establishing normal network connectivity.

Dynamics and heterogeneity of a fate determinant during transition towards cell differentiation.

Yan is an ETS-domain transcription factor responsible for maintaining Drosophila eye cells in a multipotent state. Yan is at the core of a regulatory network that determines the time and place in which cells transit from multipotency to one of several differentiated lineages. Using a fluorescent reporter for Yan expression, we observed a biphasic distribution of Yan in multipotent cells, with a rapid inductive phase and slow decay phase. Transitions to various differentiated states occurred over the course of this dynamic process, suggesting that Yan expression level does not strongly determine cell potential. Consistent with this conclusion, perturbing Yan expression by varying gene dosage had no effect on cell fate transitions. However, we observed that as cells transited to differentiation, Yan expression became highly heterogeneous and this heterogeneity was transient. Signals received via the EGF Receptor were necessary for the transience in Yan noise since genetic loss caused sustained noise. Since these signals are essential for eye cells to differentiate, we suggest that dynamic heterogeneity of Yan is a necessary element of the transition process, and cell states are stabilized through noise reduction.

Modelling chlorine residual decay as influenced by temperature

AbstractTemperature is one of the most important factors affecting chlorine decay rates in drinking water systems. In this article, temperature effect on chlorine decay rates in raw and treated waters was studied. Results show that temperature affects differently the fast and slow decay phases, the latter being more sensitive to temperature variations, as higher values of the activation energy parameter were obtained. Accordingly, an improvement to the temperature dependent two reactant model (a parallel second order model), in which the activation energies of each decay phase are distinct, is proposed and successfully used for chlorine decay modelling. In waters from transport and distribution systems, however, the fast decay phase is mostly negligible. In such cases, a single phase second‐order model in which the activation energy parameter is given by the slow phase reaction, is likely to describe temperature effect on chlorine decay accurately.

Interactive effect of acute sympathetic activation and exercise intensity on the dynamic response characteristics of vascular conductance in the human calf muscle

The effect of acute activation of the sympathetic nervous system on the dynamic response of muscle hyperaemia during exercise at different intensities is not clear. To explore this, six men performed 16, 5-min bouts of intermittent calf contractions at two intensities (25 and 50 % MVC) and two levels of sympathetic activation (CPT cold pressor test, CON control). Mean arterial pressure (MAP) and leg vascular conductance (LVC leg blood flow/MAP) were measured during rest and contractions (3 s intervals), and dynamic response characteristics of LVC were estimated using curve-fitting and empirical modeling. MAP was ~20 % greater (P ≤ 0.05) during CPT than CON before and during initial contractions at both intensities. At 25 % MVC, CPT reduced the exercise-induced change in LVC (0.109 vs 0.125 ml 100 ml(-1 )min(-1 )mmHg(-1); P < 0.05), an effect attributed to the reduction in the amplitude of the fast growth phase (0.091 vs 0.128 1 ml 100 ml(-1 )min(-1 )mmHg(-1); P < 0.05). At 50 % MVC, CPT also blunted the fast growth phase (0.147 vs 0.189 ml 100 ml(-1 )min(-1 )mmHg(-1); P < 0.05), but the total change in LVC during exercise was unaffected because of a significant reduction in the amplitude of the rapid decay phase and tendency (P = 0.1) for a lower amplitude of the slow decay phase. Increased sympathetic constraint of vasodilation persists during initial contractions but is overcome at the high intensity by a mechanism apparently related to hyperaemic decay.

Investigation of the X-Ray Emission of the Large Arcade Flare of 2 March 1993

A large arcade flare of 2 March 1993 has been investigated using X-ray observations recorded by the {\sl Yohkoh} and GOES satellites and the {\sl Compton Gamma Ray Observatory}. We analyzed quasi-periodicity of the hard-X-ray (HXR) pulses in the flare impulsive phase and found close similarity between the quasi-periodic sequence of the pulses with that observed in another large arcade flare of 2 November 1991. This similarity helped to explain the strong HXR pulses which were recorded at the end of the impulsive phase, as due to an inflow of dense plasma (coming from the chromospheric evaporation) into the acceleration volume inside the cusp. In HXR images a high flaring loop was seen with a triangular cusp structure at the top, where the electrons were efficiently accelerated. The sequence of HXR images allowed us to investigate complicated changes in the precipitation of the accelerated electrons toward the flare footpoints. We have shown that all these impulsive-phase observations can be easily explained in terms of the model of electron acceleration in oscillating magnetic traps located within the cusp structure. Some soft-X-ray (SXR) images were available for the late decay phase. They show a long arcade of SXR loops. Important information about the evolution of the flare during the slow decay phase is contained in the time variation of the temperature, $T(t)$, and emission measure, EM$(t)$. This information is the following: i) weak heating occurs during the slow decay phase and it slowly decreases; ii) the decrease in the heating determines slow and smooth decrease in EM; iii) the coupling between the heating and the amount of the hot plasma makes the flare evolve along a sequence of quasi-steady states during the slow decay phase (QSS evolution).

MAGNETIC RELAXATION, CURRENT SHEETS, AND STRUCTURE FORMATION IN AN EXTREMELY TENUOUS FLUID MEDIUM

The process of relaxation of a unidirectional magnetic field in a highly conducting tenuous fluid medium is considered. Null points of the field play a critical role in this process. During an initial stage of relaxation, variations in magnetic pressure are eliminated, and current sheets build up in the immediate neighborhood of null points. This initial phase is followed by a long diffusive phase of slow algebraic decay of the field, during which fluid is continuously sucked into the current sheets, leading to exponential growth of fluid density and concentration of mass around the null points, which show a tendency to cluster. Ultimately, this second phase of algebraic decay gives way to a final period of exponential decay of the field. The peaks of density at the null points survive as a fossil relic of the decay process. Numerical solution of the governing equations provides convincing confirmation of this three-stage scenario. Generalizations to two- and three-dimensional fields are briefly considered.

Adaptation to steady light by intrinsically photosensitive retinal ganglion cells

Intrinsically photosensitive retinal ganglion cells (ipRGCs) are recently discovered photoreceptors in the mammalian eye. These photoreceptors mediate primarily nonimage visual functions, such as pupillary light reflex and circadian photoentrainment, which are generally expected to respond to the absolute light intensity. The classical rod and cone photoreceptors, on the other hand, mediate image vision by signaling contrast, accomplished by adaptation to light. Experiments by others have indicated that the ipRGCs do, in fact, light-adapt. We found the same but, in addition, have now quantified this light adaptation for the M1 ipRGC subtype. Interestingly, in incremental-flash-on-background experiments, the ipRGC's receptor current showed a flash sensitivity that adapted in background light according to the Weber-Fechner relation, well known to describe the adaptation behavior of rods and cones. Part of this light adaptation by ipRGCs appeared to be triggered by a Ca(2+) influx, in that the flash response elicited in the absence of extracellular Ca(2+) showed a normal rising phase but a slower decay phase, resulting in longer time to peak and higher sensitivity. There is, additionally, a prominent Ca(2+)-independent component of light adaptation not typically seen in rods and cones or in invertebrate rhabdomeric photoreceptors.