Performed Quality Assessment Research Articles

Comprehensive power quality performance assessment for electrical system of a nuclear research reactor

Studying the power quality (PQ) is an essential issue to ensure the safe and accurate operation of sensitive equipment particularly for nuclear installations. Assessment of PQ involves collecting and analysing data resources and then evaluating it with reference to PQ standards. There are many alternatives for PQ and it is difficult to make an appropriate selection among them in the existence of their multiple criteria which are usually conflicted. So this selection subject can be classified as a Multi Criteria Decision Making (MCDM) problem. To do so, a reliable and scientific method for studying and evaluating the overall system PQ is required. This study aims to assess performance of PQ for the electrical power system at a Nuclear Research Reactor (NRR) during a certain period using multiple measures for the most decisive PQ phenomena. It focuses on a number of the most important PQ phenomena namely frequency fluctuation (deviation), unbalances of current and voltage, current and voltage harmonic distortion, flicker and power factor. After combining all results into six samples (alternatives), the criteria weights are determined based on an objective method for weighting which is called CRITIC method. Then, the alternatives are ranked using compromise MCDM method-VIKOR method. The obtained results are analyzed and discussed to evaluate performance of NRR electrical system from the PQ view. It showed that the compromise solution that obtained by CRITIC-VIKOR can be a guide to facilitate the PQ evaluation of nuclear installation electrical system. Also, it can empower the operators with the benefits of benchmarking and monitoring a single index instead of several indices. Moreover, it is very useful for helping stakeholders to understand how the PQ performance changes under a certain operating condition of the facility. Finally, it is can be considered as a good model to weight each PQ phenomena and identify the time intervals for best and worst total PQ in NRR.

Assessment of Production Performance and Egg Quality of Commercial Laying Hens Fed Black Pepper and Red Pepper Additives

With the increasing demand for poultry products (meat and eggs) worldwide, poultry farmers want to improve the productivity of their flocks. This challenge has necessitated poultry nutritionists to offer specific nutritional strategies for improved productivity. Feed additives are recommended as one of such strategic options, and plant materials, otherwise known as phytogenics, are being extensively investigated. Therefore, the study's objective was to assess the production performance and egg quality of commercial laying hens fed black pepper and red pepper additives. A total of 210 commercial laying hens at 24 weeks of age were allotted into seven dietary treatments in a completely randomized design. Each treatment had thirty (30) birds each, replicated three times to give ten (10) birds per replicate in a study that lasted 12 weeks. The formulated diets included: a control diet with no additives; Treatments 2 and 3 had 1% and 1.5% black pepper powder; Treatments 4 and 5 had 1% and 1.5% red pepper powder; Treatment 6 had a mixture of 0.5% each of black pepper and red pepper, while treatment 7 had a mixture of 0.75% each of black pepper and red pepper. All data collected were subjected to a one-way analysis of variance using the general linear model procedure of SAS (2012). From the results obtained, the hen day production (%) was significantly highest in hens fed the diet with 1% red pepper (83.40%) and the least from hens in the control (65.56%). The control treatment also recorded the least performances in egg mass (48.76g/bird/day) and feed conversion ratios (2.58 and 2.30). Shell thickness was least (0.43mm) in hens fed the diet with 1.5% red pepper, while the thickest shell measurement of 0.50mm was recorded in Treatment 6. The highest Haugh unit of 103.77 was obtained from Treatment 4, while the least value of 96.66 was obtained from the control. Yolk colour was significantly improved in the treated groups as against what was obtained from the control group. From the results, it can be concluded that black pepper and red pepper, having improved production performance and some egg quality characteristics in the treated groups compared to the control hold great potential as dietary additives.

Validity and reliability of the single camera marker less motion capture system using RGB-D sensor to measure shoulder range-of-motion: A protocol for systematic review and meta-analysis.

The range-of motion (ROM) is an essential component of joint mobility. Shoulder ROM measurement has been problematic due to its complexity. A marker less motion capture system can be a potential alternative for upper limb assessment. Currently, there is no systematic review to evaluate the validity of a marker less motion capture system for assessing shoulder ROM. This study aims to describe methods to evaluate the reliability and validity of a single camera marker less motion capture system that uses an RGB-depth sensor to measure shoulder ROM. Studies that measured shoulder ROM with a single camera marker less motion capture system using the RGB-depth sensor and assessed the intra- and/or inter-rater reliability, and/or validity of the device will be included. The search of electronic databases, such as MEDLINE, EMBASE, Cochran library, Cumulative Index to Nursing, and Allied Health Literature via EBSCO, IEEE Xplore, China National Knowledge Infrastructure, KoreaMed, Korean studies Information Service System, and Research Information Sharing Services will be performed for all relevant articles from inception to December 2022. Two authors will independently perform quality assessments using the Consensus-based Standards for the selection of health Measurement Instruments checklist for reliability, measurement error of outcome measurement instrument, and criterion validity. The primary outcomes will be the intra- and inter-rater reliability and validity of the markerless motion capture system measuring shoulder flexion, extension, abduction, adduction, internal rotation, or external rotation. A subgroup analysis would be performed if there are sufficient data to pool to identify an influencing factor in the measurement of ROM using a marker less motion capture system. These findings will present tools to utilize and evaluate single camera motion capture systems for the medical use for clinicians and healthcare experts and can aid in further clinical research using such a system for different movements and other joints.

The impact of intestinal stoma formation on patient quality of life after emergency surgery-A systematic review.

Elective stoma formation has a negative effect on patient quality of life (QoL), with a potential detrimental impact on body image, confidence and social functioning being shown previously. However, the impact of emergency stoma formation on QoL has been explored less frequently. This systematic review aims to synthesize all available literature exploring QoL via patient-reported outcome measures. A search strategy was implemented on 24 November 2022 across Embase, MEDLINE, PsycInfo and the Cochrane Library database after registration on PROSPERO (CRD42022370606). Studies were included if they used a standardized patient-reported outcome measure, had more than five emergency stoma patients, age > 18 years and were fully published in English. Two of three independent researchers screened articles, extracted data and performed quality assessment using the Newcastle-Ottawa Scale and the Cochrane risk of bias tool. In all, 1775 articles were screened, with 16 included in the systematic review. This included 1868 emergency stoma patients (men:women 0.53; median age 64.6 years) followed up for a median of 12 months. Patients who had a Hartmann's procedure for perforated diverticulitis had poorer QoL than those who underwent primary anastomosis. There was a negligible difference in QoL between those who had a colonic stent for obstructing colorectal cancer compared with those who underwent emergency stoma formation. Female sex, end stoma formation and ileostomy formation were all identified as risk factors for poorer QoL. Patients undergoing emergency stoma surgery have marginally poorer QoL compared with those undergoing similar procedures without stoma formation. Further work is required to identify risk factors associated with this and also to compare QoL after stoma reversal.

Prevalence of Hypertension Among Tribal Population in India: A Systematic Review and Meta-Analysis

Hypertension is an important worldwide public-health challenge and it is accountable for 7% of Disability Adjusted Life Years (DALY) loss, and by the end of 2025 about 29% of world’s population is likely to suffer from hypertension. Tribal population constitute about 8% of the total population in India. Among tribal population, study on hypertension will provide an interesting outcome because studies across the world have shown a lower prevalence. The objective of the study was to estimate the pooled prevalence of hypertension among adult tribal populations in India and also to analyse the possible sources of heterogeneity in the estimate. A systematic search was performed in PubMed, Google scholar, Scopus, Embase MEDLINE, and journals for articles published between 2001 and 2020. This is a systematic review and meta-analysis done on hypertension among tribal populations of India. Three authors independently reviewed the articles, performed quality assessment and data was extracted. Pooled estimate of hypertension was calculated. Subgroup analyses was performed. A total of 26 articles with a total number of subjects of 75,543 were included in the study. The pooled estimate of hypertension prevalence was 25.1% (95% CI: 24.7, 25.4). There was significant heterogeneity among the studies (I2 = 98.2 and Q = 1289.37). It is essential to conduct larger cohort studies and randomised controlled trials to determine the causes of the increased prevalence of hypertension among the tribal population. The prevalence of hypertension among tribal population are essential as a source of primary information and for rational planning of health services and will help public-health policy-makers to assign sufficient priority and resources for its management and prevention.

Integrating social support into interventions among the elderly in nursing homes: a scoping review

ObjectivesThis study aimed to understand the evidence related to integration of social support into interventions, to identify literature gaps related to social support interventions, and to clarify dimensions of supportive...

Risk of endometrial cancer in patients with polycystic ovarian syndrome: A meta‑analysis.

While existing literature suggests an association between polycystic ovarian syndrome (PCOS) and endometrial cancer, the sparsity and inconsistency of current evidence indicates a lack of clarity regarding the exact strength of this association. It also remains uncertain whether the degree of risk of disease is affected by confounding factors, such as age and body mass index (BMI). The present meta-analysis is aimed to quantify the risk of endometrial cancer in female subjects with PCOS compared to those without PCOS. PubMed, MEDLINE, EMBASE, Scopus and Cochrane were searched from inception to October 31, 2022, to identify peer-reviewed case-control, cohort and cross-sectional studies that assessed the association between endometrial cancer and PCOS and contained original data. Two researchers independently extracted data and performed quality assessment using the Newcastle-Ottawa criteria. Pooled odds ratios (ORs) were calculated using the random-effect model and inverse variance. The degree of heterogeneity was assessed using I2 statistics. A total of 10 relevant studies were identified and included in the meta-analysis (comprising 12,248 female patients with PCOS and 54,120 controls). Females with PCOS had a significantly increased odds of developing endometrial cancer as compared to those without PCOS [OR, 4.07; 95% confidence interval (CI), 2.13-7.78; P<0.0001]. When postmenopausal subjects (age, >54 years) were excluded from the meta-analysis, the odds increased further (OR, 5.14; 95% CI, 3.22-8.21; P<0.00001). Patients with PCOS are up to 5 times more likely to develop endometrial cancer compared to those without PCOS. Larger, prospective studies that are well-controlled for confounding factors, such as BMI, are required.

Diagnostic accuracy of sonication fluid cultures from prosthetic components in periprosthetic joint infection: an updated diagnostic meta-analysis

BackgroundPeriprosthetic joint infection (PJI) is the most serious complication following total joint arthroplasty (TJA) and has a significant impact on patients and the national healthcare system. To date, the diagnosis of PJI is still confronted with dilemmas. The present study investigated the validity of sonication fluid culture (SFC) for removing implants in the diagnosis of PJI after joint replacement.MethodsFrom database establishment to December 2020, relevant literature was retrieved from the PubMed, Web of Science, Embase and Cochrane Library databases. Two reviewers independently performed quality assessment and data extraction to calculate the pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), area under the curve (AUC) and diagnostic odds ratio (DOR) to evaluate the diagnostic value of overall SFC for PJI.ResultsA total of 38 eligible studies including 6302 patients were selected in this study. The pooled sensitivity, specificity, PLR, NLR, and DOR of SFC for PJI diagnosis were 0.77 (95% confidence interval [CI], 0.76–0.79), 0.96 (95% CI, 0.95–0.96), 18.68 (95% CI, 11.92–29.28), 0.24 (95% CI, 0.21–0.29), and 85.65 (95% CI, 56.46–129.94), respectively, while the AUC was 0.92.ConclusionThis meta-analysis showed that SFC was of great value in PJI diagnosis, and the evidence of SFC on PJI was more favorable but not yet strong. Therefore, improvement of the diagnostic accuracy of SFC is still necessary, and the diagnosis of PJI continues to warrant a multiplex approach before and during a revision procedure.

Cardiovascular Risk Factors in Patients With Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis.

The interruption of vascular supply to the inner ear is one of several proposed etiologies of sudden sensorineural hearing loss (SSNHL). The increased presence of cardiovascular risk factors may predispose patients to SSNHL through this pathway. This systematic review and meta-analysis studies the presence of cardiovascular risk factors in patients diagnosed with SSNHL. Databases included PubMed/Medline, OVID, EMBASE, Cochrane, and Web of Science. Inclusion criteria included studies featuring SSNHL patients presenting with 1+ cardiovascular risk factors. Exclusion criteria included case reports and studies without outcome measures. Two investigators independently reviewed all manuscripts and performed quality assessments using validated tools. Of 532 identified abstracts, 27 studies met inclusion criteria (19 case-control, 4 cohorts, 4 case series). Of these, 24 underwent meta-analysis encompassing a total of 77,566 patients (22,620 SSNHL patients, 54,946 matched controls). The mean age was 50.43 years. SSNHL patients were more likely to have concomitant diabetes (odds ratio [OR]1.61 [95% confidence interval [CI]: 1.31, 1.99; p < .00001]) and hypertension (OR 1.5[95% CI: 1.16, 1.94; p = .002]). An increased standard mean difference of total cholesterol of 11.09 mg/dL (95% CI; 3.51, 18.67; p = .004) was noted in the SSNHL group compared with the controls. No significant differences in smoking, high-density lipoprotein, triglycerides, or body mass indexwere detected. Patients presenting with SSNHL have a significantly higher risk of concomitant diabetes, hypertension, and higher total cholesterol in comparison to matched controls. This may indicate a higher cardiovascular risk profile in this population. More prospective and matched cohort studies are needed to understand the role of cardiovascular risk factors in SSNHL.

Shigellosis in Southeast Asia: A systematic review and meta-analysis.

Southeast Asia is attractive for tourism. Unfortunately, travelers to this region are at risk of becoming infected with Shigella. We conducted a meta-analysis to provide updates on Shigella prevalence in Southeast Asia, along with their serogroups and serotypes. We conducted a systematic search using PubMed, EMBASE, and Web of Science for peer-reviewed studies from 2000 to November 2022. We selected studies that detected Shigella in stools by culture or polymerase chain reaction (PCR). Two reviewers extracted the data using a standardized form and performed quality assessments using the Joanna Briggs Institute checklist. The random effects model was used to estimate the pooled prevalence of Shigella. During our search, we identified 4376 studies. 29 studies (from six Southeast Asian countries) were included in the systematic review, 21 each in the meta-analysis of the prevalence of Shigella (Sample size: 109545) and the prevalence of Shigella serogroups. The pooled prevalence of Shigella was 4% (95% CI: 4-5%) among diarrhea cases. Shigella sonnei was the most abundant serogroup in Thailand (74%) and Vietnam (57%), whereas Shigella flexneri was dominant in Indonesia (72%) and Cambodia (71%). Shigella dysenteriae and Shigella boydii were uncommon (pooled prevalence of 1% each). The pooled prevalence of Shigella was 5% (95% CI: 4-6%) in children aged <5 years. The pooled prevalence showed a decreasing trend comparing data collected between 2000-2013 (5%; 95% CI: 4-6%) and between 2014-2022 (3%; 95% CI: 2-4%). Shigella prevalence was 6% in studies that included participants with mixed pathogens versus 3% in those without. Shigella flexneri serotype 2a was the most frequently isolated (33%), followed by 3a (21%), 1b (10%), 2b (3%), and 6 (3%). This study provides compelling evidence for the development of effective Shigella vaccines for residents of endemic regions and travellers to these areas.

Technical Perspective for Video Based Assessment of Surgeries in Low-Resource Settings

Scalable digital learning environments are essential to sustain surgical training programs worldwide. Detailed images of surgeries enriched with educational annotations are vital to train the eyes of the learners. Here, we report a low-cost method, deployed in a low-resource setting in West Africa, which may contribute to the growth of use in open-sourced digital surgical resources world-wide. This paper is based on the authors participatory and observational experiences creating surgical video content by way of recording surgical procedures and reflecting on field notes and video content. All surgeries were recorded between January and December 2018. Masanga Hospital, a rural district hospital in Sierra Leone, West Africa. Thirty-five patients undergoing inguinal hernia repair, elective caesarian section, salpingectomy, bowel resection, hydrocele repair, or below-knee amputation consented for recording their surgical procedure and using the anonymized material for educational purposes. This manual for non-professional cinematographers provides chronological steps for shooting a surgical procedure in a low-resource setting. Recording a surgical procedure to explain surgical techniques, and perform quality assessment through error analysis and coaching requires more than just point-and-shoot. While taking into account local customs and possibilities, practical tips were provided to prepare for the set-up, and recording of a surgical procedure in a low-resourced setting. Commercially available digital video technology allows for filming high-quality surgical procedures for educational purposes at rural district hospitals in a low-resource setting.

Anxiety and stress among healthcare professionals during COVID-19 in Ethiopia: systematic review and meta-analysis

ObjectiveThis study intended to assess the impact of COVID-19 pandemic on anxiety and stress among healthcare professionals in Ethiopia.DesignThis study applied a design of systematic review and meta-analysis of observational...

Impact of social media on mental health of the general population during Covid-19 pandemic: A systematic review.

During the COVID-19 pandemic, people are using social media more than usual routine because they rely on online sources to seek health information for themselves and their loved ones. The spread of inaccurate and misleading information via social media has a number of detrimental psychological effects on members of society. The aim of this systematic review was to describe the impact of social media on the mental health of the general population. An extensive systematic search was done till the last month of 2021 for collecting the evidence using the PRISMA technique. The search was mainly focused on the article leading with keywords and search engines used during the course of the study were Pubmed, Semantic Scholar, Mendeley, and Science direct. Articles for this study were selected based on the predetermined eligibility criteria and performed quality assessment by using the NHLBI quality assessment tool. Most of the studies included in this review are found fair (score between 9 and 12) quality. Out of 866 publications, 533 articles were included in the initial screening, after duplication removal 46 full-text articles were assessed for eligibility and 14 studies were selected for systematic review. In most of the studies, maximum participants used social media as a primary source of information. Relatively high rates of symptoms of depression (14.14% to 48.3%), anxiety (7.4% to 47.82%), and prevalence of stress increased to 37.67% are reported after exposure to social media for coverage of COVID-19 news in the general population. Risk factors of psychological distress are associated with female gender, younger age group, marital status, staying alone, and duration of exposure to mass media. Increased exposure to COVID-19 information through mass/social media is associated with highly significant levels of psychological health issues; mitigating the hazardous effect of social media exposure during the COVID-19 pandemic on the psychological health of the general population is an international public health priority.

A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder.

There are now hundreds of systematic reviews on attention deficit hyperactivity disorder (ADHD) of variable quality. To help navigate this literature, we have reviewed systematic reviews on any topic on ADHD. We searched MEDLINE, PubMed, PsycINFO, Cochrane Library, and Web of Science and performed quality assessment according to the Joanna Briggs Institute Manual for Evidence Synthesis. A total of 231 systematic reviews and meta-analyses met the eligibility criteria. The prevalence of ADHD was 7.2% for children and adolescents and 2.5% for adults, though with major uncertainty due to methodological variation in the existing literature. There is evidence for both biological and social risk factors for ADHD, but this evidence is mostly correlational rather than causal due to confounding and reverse causality. There is strong evidence for the efficacy of pharmacological treatment on symptom reduction in the short-term, particularly for stimulants. However, there is limited evidence for the efficacy of pharmacotherapy in mitigating adverse life trajectories such as educational attainment, employment, substance abuse, injuries, suicides, crime, and comorbid mental and somatic conditions. Pharmacotherapy is linked with side effects like disturbed sleep, reduced appetite, and increased blood pressure, but less is known about potential adverse effects after long-term use. Evidence of the efficacy of nonpharmacological treatments is mixed. Despite hundreds of systematic reviews on ADHD, key questions are still unanswered. Evidence gaps remain as to a more accurate prevalence of ADHD, whether documented risk factors are causal, the efficacy of nonpharmacological treatments on any outcomes, and pharmacotherapy in mitigating the adverse outcomes associated with ADHD.

The place and role of automated systems in mechanical engineering

Introducing off-the-shelf solutions for automated machine-building systems causes some difficulties related to attempts to change the algorithms of process participants, and also to the need to duplicate information transfer chains, as most systems operate autonomously within certain production units. The author proposes a new approach to organizing the interaction of automated systems of machine-building enterprises. Effective implementation of automated systems is possible only based on investigation and optimization of machine-building enterprise activities, and based on analysis and quality assessment of functions performance by participants of different enterprise processes. The method comprises identifying the process for preparing production and output of finished products, and processes of lower levels (auxiliary), but necessary for implementing the main, and functionally related to it. The main functional process defines a time parameter and auxiliary processes accompanying the main process. These auxiliary processes are financial, material, personnel, and organizational support processes. The article contains the basic principles of creating a complex of automated machine-building systems. The article analyzes the role and place of each of the main functional automated systems. The author gives considerations on the sequence of implementation of the project of digitalization of machine-building production.

School Evaluation for Quality Improvement as The Gaze

Within this paper, the authors examine the school performance quality assessment system in Lithuania from the standpoint of pedagogical staff who find themselves in the status of the assessed. The philosophical concept of The Gaze is used for the interpretation of the results of a quantitative and qualitative survey. The concept of the Gaze, as conceptualized by Sartre and Foucault, helps to understand the sense of tension between freedom and control as experienced by pedagogical staff who find themselves in the status of the assessed. The authors, by applying principles of phenomenological interpretative analysis and descriptive statistics, examine the process of school performance quality assessment as experienced by teachers. The informants identify themes such as stress, distress, work simulation, and creativity restrictions. The authors conclude that school performance quality assessments do emerge as the Gaze, and furthermore as a dilemma of communication known as the Double Bind, when at the same time contradictory objectives are held, and a regressive state of stress and distress is generated as a result. On the bases of results of their research, the authors suggest that the actual school performance quality assessment system in Lithuania must be fundamentally improved by applying the empowering consultancy approach, while measures of quality assessment should be focused on objective indicators of school performance quality assessment.

Oral herbal medicine for treatment of postherpetic neuralgia: A protocol for systematic review and meta-analysis.

Postherpetic neuralgia (PHN) is the most common complication of shingling. Herbal medicine for PHN is clinically used to improve chronic pain and other symptoms that reduce the quality of life (QoL), such as sleep disturbances and emotional problems. This study aims to describe methods for synthesizing evidence for the effectiveness and safety of herbal medicine for treating PHN. Randomized controlled trials using herbal medicine in patients with PHN will be included in this review. Electronic databases such as MEDLINE via PubMed, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, China National Knowledge Infrastructure, WanFang, KoreaMed, Research Information Service System, Korean Studies Information Service System, Database Periodical Information Academic, Oriental Medicine Advanced Searching Integrated System, and Korea Citation Index will be searched without language limitations from their inception to September 2022. Two authors will perform quality assessments independently using the Cochrane risk-of-bias tool. The primary outcome will be pain intensity, and the secondary outcomes will be global impression, anxiety, depression, sleep disturbance, QoL, and safety. All data from eligible studies will be synthesized for meta-analysis. This study will be a systematic review and meta-analysis to evaluate the effectiveness and safety of oral herbal medicine for treatment of PHN. This study will provide evidence for herbal medicine as a potential treatment for PHN which is advantageous not only for patients but also for researchers and policymakers.

External quality assessment of laboratory performance in bacteriology in the Eastern Mediterranean Region, 2011-2019.

Since 2007, national public health laboratories in the WHO Eastern Mediterranean Region (EMR) have participated in a regional external quality assessment scheme in bacteriology to improve testing proficiency. To assess laboratory performance in bacteriology in the EMR between 2011 and 2019 using the regional external quality assessment scheme. We analysed the accuracy of participant-reported data in bacterial identification, Gram stain microscopy, and antimicrobial susceptibility testing. For each category, we assessed the performance over time, the performance on multiple organisms, and whether a laboratory repeatedly failed to attain satisfactory results. Between 2011 and 2019, 70% of laboratories achieved satisfactory performance for bacterial identification and antimicrobial susceptibility testing, and 85% performed satisfactory Gram stain microscopy. Testing did not improve on multiple organisms and results were consistently low for some pathogens and test categories. Twenty-nine percent of laboratories underperformed throughout the study period. The unchanged performance over time and underperformance of laboratories highlight the need for improvements in the regional external quality assessment scheme. Participating laboratories and WHO need to work more actively to strengthen the problem areas.

CCHZ‐DISO: A Timely New Assessment System for Data Quality or Model Performance From Da Dao Zhi Jian

AbstractWith the rapid development of big data, assessment of data quality or model performance has become a hot scientific question. However, most existing lots of metrics focus on specific aspects of the assessment, and comprehensive assessment is rare. Therefore, it is very necessary to develop new assessment system. To address this problem, a new assessment system is constructed which is named after Chen, Chen, Hu, and Zhou (CCHZ)‐distance between indices of simulation and observation (DISO) according to the contributions of Xi Chen, Deliang Chen, Zengyun Hu, and Qiming Zhou. CCHZ‐DISO system builds on the Euclidean Distance and flexible determination of statistical metrics and their numbers. Due to its simplicity and flexibility, CCHZ‐DISO can be readily and widely applied to any subject of science. Therefore, it follows the principle of the Chinese philosopher Lao Zi's Da Dao Zhi Jian which means that the most basic truth is very simple.

Brain natriuretic peptide and N-terminal brain natriuretic peptide for the diagnosis of haemodynamically significant patent ductus arteriosus in preterm neonates.

Brain natriuretic peptide and N-terminal brain natriuretic peptide for the diagnosis of haemodynamically significant patent ductus arteriosus in preterm neonates.