To explore the characteristics and strategies of stem cell collection in children with Transfusion-dependent thalassemia (TDT) undergoing gene therapy. To summarize the challenges encountered and the countermeasures taken during stem cell collection in 13 TDT children undergoing gene therapy at the Department of Pediatrics, 923rd Hospital of the Joint Logistics Support Force of PLA between August 2020 and January 2024. Among the 13 TDT children, one required 1 collection, nine required 2 collections, one required 3 collections, and one required 4 collections. Adequate cells were collected in 12 cases, while 1 case had failed to obtain sufficient CD34+ cells despite multiple rounds of collection. The stem cell collection process was smooth in all 13 cases, with no adverse reactions. The stem cell mobilization regimen for TDT children needs to be enhanced, and saturated blood transfusion should be performed prior to stem cell collection.

Implementing a burns treatment protocol for paediatric patients in secondary hospital settings.

Epidural analgesia is an effective analgesic method for children throughout the postoperative phase. The post-operative urinary retention affects the post-operative recovery immensely. Many studies look at post-operative urinary retention in adults who receive epidural analgesia, while there is a paucity of data in children. This is a study that addresses the question of post-operative urinary retention in children in whom epidural analgesia is employed. This is a prospective study undertaken in the pediatric surgery department of Christian Medical College in Vellore. Children enrolled in the trial got epidural analgesia both during and after surgery. They weren't catheterized before the surgery. Those who had urinary retention were identified with ultrasound and were catheterized. Data were prospectively collected and analyzed. A total of 157 children participated in this study. Epidural bolus and infusate were either Ropivacaine or Bupivacaine. Sixteen children developed post-operative urinary retention, yielding an overall incidence of 10.2%. Children who were below 2 years of age had no postoperative urinary retention (95% CI: 0.0%-10.9%). Those aged 2 years and above had an incidence of 12.8% (95% CI: 8.0%-19.8%). The likelihood of voiding is 1.15 times higher in children under the age of 2 than in those 2 years and above (Relative Risk (RR): 1.15, 95% CI: 1.07 to 1.23). The incidence of POUR was 13.2% in girls and 7.9% in boys (RR: 1.68, 95% CI: 0.66-4.29, p = 0.270). POUR was observed by 9.6% of the group without the opioid additive and 11.1% of the group with the opioid additive (RR: 0.862, 95% CI: 0.338-2.19). The rate of POUR increased with surgical duration, from 6.1% in procedures < 120 min to 10.8% in procedures with 120 to 180 min and 16.0% in those exceeding 180 min. The bolus used at induction, the Bupivacaine group had 13 out of 124 patients (10.5%) with POUR, and the Ropivacaine group had 3 out of 33 patients (9.1%) with POUR (RR: 1.15, 95% CI: 0.349 to 3.81). The level of epidural placement was not found to be a significant predictor in this study. This study found a rising trend in POUR incidence with age, signifying that older children are more likely to have POUR. This supports a selective, age-guided approach to bladder catheterization in pediatric epidural practice, though larger prospective studies are needed to establish evidence-based thresholds.

Housemanship is a transitional phase that prepares medical graduates to become safe, independent practitioners. Learning during this phase occurs through patient-case talk with senior doctors, a hybrid interaction that serves patient care and learning. Effective case-based learning has been linked to fostering participation, dialogue and strategic language use, with Socratic questioning recognised as a key scaffolding approach. However, discursive evidence of how such questioning unfolds in everyday training remains limited. This study examines how house officers and senior doctors formulate questions and responses to facilitate teaching and learning in two training contexts. We performed a discourse analysis of naturally occurring patient-case talk between house officers and senior doctors in the Paediatrics Department of a teaching hospital in Kuala Lumpur. Audio-recorded interactions produced 21 units of patient-case talk from five Continuing Medical Education (CME) sessions and 78 units from 13 Ward Rounds (WRs). Drawing on concepts of questioning and responding practices, the analysis identifies how senior doctors design questions to scaffold learning and how house officers orient to these designs in producing responses. Senior doctors use varied questioning practices to scaffold developing expertise and promote self-correction. In CME sessions, they frequently use polar questions and designedly incomplete utterances, with house officers displaying interactional agency through repetitional and transformative responses. During ward rounds, senior doctors rely more on wh-questions, often paired with designedly incomplete utterances, to stimulate reasoning and self-initiated repair. Collectively, these practices foster reflection, critical thinking and discovery-based learning without prematurely providing answers. This paper demonstrates how questioning functions as a key discursive resource for scaffolding expertise in Malaysian medical training. It extends understanding of Socratic questioning by showing how distinct question designs support self-correction, reasoning and learner agency across teaching contexts. Strategic questioning allows senior doctors to address knowledge gaps in a manner that aligns with principles of psychological safety. As a result, house officers engage in the interactional display of a clinical voice and demonstrate an orientation toward managing uncertainty as part of learning. These insights provide actionable, evidence-based direction for faculty development and clinical teaching practice.

Background: Perinatal asphyxia is a leading cause of neonatal hospital admission, particularly in low- and middle-income countries. It causes diminished oxygen supply to brain resulting hypoxic ischaemic encephalopathy with three distinct stages. Higher HIE grades have been associated with reduced calcium levels. This emergency condition can lead to multi-organ dysfunction and can affect the neonatal calcium profile causing mainly hypocalcemia. Objective: To compare the serum calcium level among different stages of Hypoxic ischaemic encephalopathy (HIE) in perinatal asphyxia Methods: This cross-sectional observational study was conducted in department of Paediatrics, Rangpur medical college hospital on 212 neonates with perinatal asphyxia with different stages of HIE. Results: Among 212 neonates birth asphyxia was predominant in male (56.5%). Birth asphyxia was predominant in vaginal delivery (64%). Majority of the neonates were in HIE stage II (58.5%) followed by stage III (21.7%) and stage I (19.8%). Serum calcium level was significantly lower in stage III to stage-II HIE (5.1±1.66 vs 6.1±1.1.54, p-value=0.0003) and stage II to stage-I (6.1±1.1.54 vs 7.2±1.35, p-value=.0003). Conclusion: Serum calcium level tends to decrease in asphyxiated neonate which is most subjacent in HIE stage III. J Rang Med Col.2026 Mar;11(1): 69-72

Background: Acute watery diarrhea (AWD) continues to be a primary cause of morbidity and mortality in children under five. Oral rehydration solution (ORS) is a simple and affordable technique demonstrated to minimize the complications and death associated with dehydration. Objective: The effective use of ORS is frequently affected by parental socio-demographic factors. Methods: The cross-sectional study was carried out at the Department of Paediatrics, Jalalabad Ragib - Rabeya Medical College Hospital (JRRMCH), Sylhet. All children under the age of 5 years with AWD admitted to the paediatrics ward comprised the study population. Among them, a total of 300 children were selected with purposive sampling. The duration of the study was 6 months. A questionnaire was used to collect data on the sociodemographic characteristics of the study population, as well as maternal knowledge and practices regarding oral rehydration solution (ORS) and their impact on appropriate utilization of ORS were documented. Results: Most of the mothers (67%) correctly prepared ORS but only 54.3% utilized it appropriately. Among the 300 children, most of them belonged to 1 to 2 years of age group and male children were affected by diarrhoea more (61.7%), but inappropriate utilization of ORS was also predominant in male children (p &lt;0.05). Most of the mothers were in 20 to 30 years of age (75%), resided in rural areas (77%) and were home makers (95.3%). Parents with higher education and better financial condition were associated with improved utilization of ORS (p&lt;0.05). Fathers having business or in service were found utilizing ORS more efficiently than farmers (p &lt;0.05). Apart from sociodemographic factors, maternal knowledge regarding ORS also influenced appropriate use of it. More than 97% of mothers knew about ORS while only 10.7% accurately knew its purpose of replacing salt and water and this group had used ORS significantly better than other groups. Approximately half of the mothers were advised by doctors and good number of them used ORS appropriately (p&lt;0.05). Only 48 % of mothers knew the preservation time of ORS. Majority of the mothers (38%) used cup- spoon for providing ORS to their children, and 75.3% mothers also took ORS along with their children. Food restriction was also a common practice during diarrhoealillness including both babies (59.7%) and mothers (45.7%). Conclusion: This study showed that most of the mothers were familiar with ORS and its preparation. There were several factors which influenced the appropriate utilization of ORS including gender, parental education, monthly income, source of information and knowledge regarding function of ORS. J Rang Med Col.2026 Mar;11(1): 111-118

To compare automated closed-loop oxygen therapy using the FreeO2 device versus conventional manual oxygen therapy with regard to length of hospital stay among spontaneously breathing infants with bronchiolitis. Multicentre randomised controlled trial conducted from 2018 to 2023. Ten paediatric departments across France. 103 infants, 1-12 months of age, hospitalised for acute bronchiolitis requiring oxygen therapy with SpO2 <92%, excluding severe bronchiolitis. Patients were randomised to receive either automated oxygen administration via the FreeO2 device or conventional manual administration. The primary endpoint was length of hospital stay in hours from emergency admission to discharge. Secondary endpoints included re-hospitalisation at 7 and 30 days, use of non-invasive ventilation (NIV), transfer to intensive care within 3 days and time spent in hypoxia (SpO2<92%) or hyperoxia (SpO2>98%). The median hospital stay was 71.00 hours (IQR 45.8-97.6) in the FreeO2 group and 69.6 hours (IQR 47.5-116.7) in the manual group (p=0.39). The percentage of time within the oxygen target zone was 89.4% in the FreeO2 group vs 74.9% in the manual group (p<0.05). Median oxygen flow was 0.1 L/min (IQR 0.1-0.2) in the FreeO2 group vs 0.3 L/min (IQR 0.2-0.5) in the manual group (p<0.05). The groups did not significantly differ in re-hospitalisation at D7 (p=1.00) or D30 (p=1.00) or NIV use (p=0.47). While we did not find evidence of a reduced length of stay, which may be due to low study recruitment, we did find the FreeO2 device yielded a positive reduction in flow rates of oxygen.

The objective of this study was to investigate differences between familial Mediterranean fever (FMF) patients with symptom onset at aged 2 years or younger and those with later onset, with a focus on clinical presentation, disease course, and treatment outcomes. The medical records of FMF patients aged 0 to 18 years who were followed in the Pediatric Rheumatology Department between 2013 and 2024 were reviewed. Patients with symptom onset at aged 2 years or younger were classified as having early-onset, and patients with missing data or <6 months of follow-up were excluded. A total of 1255 patients with FMF were divided into 2 groups according to the age at symptom onset: ≤2 years (early-onset FMF, n = 346) and >2 years (later-onset FMF, n = 909). Early-onset FMF patients exhibited longer diagnostic delays, higher attack frequency, and more frequent fever attacks compared with later-onset patients (P < 0.05). Disease severity and the prevalence of colchicine-resistant FMF were higher in the early-onset group (P = 0.021 and P = 0.002). M694V homozygosity was more common among early-onset FMF patients (29.9% vs. 22.1%, P = 0.005). In multivariate analysis, a family history of colchicine-resistant FMF (OR = 2.64, 95% CI: 1.48-4.71) and fever (OR = 3.05, 95% CI: 2.12-4.40) were identified as independent predictors of early disease onset FMF. Early-onset FMF is associated with a more severe clinical presentation, including higher disease severity, increased colchicine resistance, and a greater frequency of M694V homozygosity. A family history of colchicine-resistant FMF is an independent predictor of early onset, highlighting the importance of detailed family history assessment in clinical practice.

Background: Appropriate complementary feeding plays a vital role in ensuring optimal growth, development, and survival of children. In developing countries such as Bangladesh, inadequate maternal knowledge and inappropriate weaning practices contribute significantly to child malnutrition and related health complications. Objective: This study aimed to assess the level of knowledge and practices regarding weaning food among mothers of children aged 6–24 months in an urban healthcare setting in Dhaka, Bangladesh. Methods: A descriptive cross-sectional study was conducted among 195 mothers attending the Pediatric Outpatient Department of Kurmitola General Hospital, Dhaka. Data were collected through face-to-face interviews using a pre-tested semi-structured questionnaire. The questionnaire included sections on socio-demographic characteristics, knowledge of weaning, and feeding practices. Data were analyzed using SPSS version 17, and descriptive statistics such as frequency, percentage, mean, and standard deviation were calculated. Results: The mean age of respondents was 26.76 ± 5.76 years. Awareness of exclusive breastfeeding for the first six months was high, with 95.4% of mothers reporting knowledge of this recommendation. However, only 43.0% correctly identified six months as the appropriate age for initiating complementary feeding, revealing a substantial gap between general awareness and specific knowledge. Regarding complementary feeding practices, 48.2% of mothers-initiated weaning at the recommended age, while the remainder introduced complementary foods either earlier or later than advised. Overall, 42.5% of mothers demonstrated good knowledge and 50.0% had moderate knowledge. In contrast, only 35.0% exhibited good feeding practices, whereas 50.0% showed average practices, underscoring a clear disparity between knowledge and its practical application. Feeding frequency was relatively appropriate, with 69.2% of mothers providing 3–4 meals per day. Similarly, 65.1% of mothers maintained proper hygiene during feeding. Despite these positive indicators, the comparatively lower proportion of mothers with good overall practices suggests that awareness alone does not consistently translate into optimal complementary feeding behaviors.Bottom of Form Conclusion: The study found that although most mothers had moderate knowledge about weaning, this knowledge was not consistently reflected in their feeding practices. A clear gap existed between awareness and implementation, as only a limited proportion of mothers demonstrated good complementary feeding practices despite relatively higher knowledge levels. These findings indicate that knowledge alone is not enough to ensure appropriate weaning behaviors. Practical barriers, cultural influences, and challenges in applying learned information may contribute to suboptimal practices. This highlights the need to examine not only maternal awareness but also the broader contextual factors that shape feeding behaviors. From a practical perspective, interventions should go beyond information sharing and focus on skill-based counseling, behavior change strategies, and community-level support. Addressing these areas is essential to bridge the knowledge–practice gap and improve complementary feeding practices, ultimately enhancing child nutrition outcomes in Bangladesh.

Blood disorders in children can present with a wide range of nonspecific symptoms, which may overlap with other conditions. Traditional diagnostic methods can sometimes struggle to identify the underlying cause. Whole-exome sequencing (WES)-is increasingly recognized as a valuable diagnostic tool, as early genetic diagnosis can offer clarity, enabling more personalized treatment approaches and improving prognostic accuracy. Between January 2022 and December 2024, 67 patients at the pediatric hematology department of Maternity and Children Hospital in Makkah, Saudi Arabia, underwent WES after conventional diagnostic methods failed to provide definitive diagnoses. We retrospectively analysed their results. The study included 67 patients with an average age of 6.5 ± 4.6 years (range 0.1-18 years), 53% of whom were male. The majority (88%) were of Saudi descent. WES provided a molecular diagnosis for 49% (n = 33) of the patients, identifying pathogenic or likely pathogenic variants. In 11% (n = 8) of the patients, no variants were found, whereas 38% (n = 26) had variants of uncertain significance in phenotype-related genes. A nonhematological diagnosis was given to 28% of the patients. Whole-exome sequencing is a valuable tool for diagnosing challenging pediatric blood disorders. The findings also underscore its importance in identifying complex or multifactorial disorders.

This study aimed to evaluate Turkish parents' perceptions and attitudes regarding the appropriate age for circumcision, practice conditions, and procedural indications across different regions of Turkey. This cross-sectional survey study was conducted between March 2023 and March 2025 across urology and pediatric surgery departments in seven distinct regions of Turkey. A total of 637 literate parents (aged ≥ 18) completed a voluntary 16-question online survey via a URL or QR code. Subgroup analysis was performed for parents whose sons had already undergone circumcision (n = 404). Data regarding demographics, circumcision preferences, and information sources were analyzed using descriptive statistics and Chi-square tests. The majority of parents (95.1%) considered circumcision necessary, primarily citing religious (77.7%) and medical (63.8%) reasons. Overall, 76% of participants stated that circumcision should ideally occur outside the psychologically sensitive period (PSP; ages 2-6). Among the 404 parents with already-circumcised sons, 41.1% (n = 166) reported that the procedure was performed during the PSP (ages 2-6). Awareness of the non-PSP increased significantly with higher parental education levels (p < 0.001). Regarding practice, specialists were preferred (pediatric surgeons 54.4%; pediatric urologists 46.3%), and the operating room was identified as the safest setting by 91.7% of respondents. Local anesthesia was the most preferred method (51.6%). Despite high awareness regarding specialist qualifications and clinical settings, a significant "knowledge-practice gap" exists concerning the timing of circumcision. Clinicians should proactively counsel parents regarding the psychological risks associated with the PSP, and public health strategies must move beyond general awareness to provide targeted guidance that ensures optimal timing in circumcision.

Pediatric MRI Safety: Frequency, Types, and Severity of Zone IV MRI Safety Events at Five U.S. Children's Hospitals.

Objective: To compare the efficacy of different nasal continuous positive airway pressure (NCPAP) weaning strategies in preterm infants presenting with respiratory distress syndrome (RDS). Methodology: This randomised controlled trial was conducted at the Department of Paediatrics, Dr. Ziauddin University Hospital, Karachi, Pakistan, from July to December 2024. It included preterm infants with gestational ages between 28 to &lt; 37 weeks and low birth weight (&lt;2500 grams) presenting with RDS. Group-A underwent sudden weaning of NCPAP, Group-B had gradual weaning with time off NCPAP, and Group C underwent pressure weaning. Outcome measures included weaning success, total days on NCPAP and length of hospital stay. Data were analysed using IBM-SPSS Statistics, version 26.0. Results: Seventy-five infants participated, with 39 (52.0%) females, and a mean age of 3.35±3.49 hours. NCPAP weaning was successful in 69 (92.0%) cases. There was no significant difference in weaning success rates among different strategies (p=0.581). The day of NCPAP weaning initiation showed a significant correlation with weaning strategies (p&lt;0.001). The successful weaning day was also significantly correlated with weaning strategies (p=0.001). Duration of NCPAP was significantly different between groups (p=0.002). Hospitalisation duration was significantly shorter in the sudden weaning group (8.52±5.65 days) compared to the gradual (12.32±5.73 days) and pressure weaning groups (11.80±5.55 days) (p=0.041). Conclusion: Infants subjected to sudden NCPAP weaning had a significantly shorter overall duration of NCPAP, leading to a significantly reduced total duration of hospitalisation compared to those undergoing gradual or pressure weaning. Success rates for sudden, gradual, and pressure NCPAP weaning varied but without significant differences.

Bronchial mucus plugs in children with Mycoplasma pneumoniae pneumonia (MPP) are often associated with severe clinical presentations, but diagnosing this condition currently depends largely on invasive bronchoscopy. This study aimed to identify clinical risk factors for mucus plug formation and to evaluate the predictive value of chest thin-section CT imaging features in diagnosing bronchial mucus plugs. This retrospective study included 186 children (aged 3-15 years) diagnosed with MPP at the Department of Pediatrics, the Hospital of 82nd Group Army PLA, between May 2023 to June 2024. All patients underwent chest thin-section CT and bronchoscopy. Based on bronchoscopic findings, participants were divided into a mucus plug group (n = 54, 29%) and a non-mucus plug group (n = 132, 71%). Clinical characteristics, inflammatory markers (blood counts, C-reactive protein [CRP], lactate dehydrogenase [LDH]), and CT imaging features (bronchial obstruction, bronchiolitis, lung consolidation) were compared. Univariate and multivariate logistic regression analyses were performed to identify risk factors. Patients were further classified into radiological mucus plug (n = 59) and non-mucus plug (n = 127) groups based on CT-detected bronchial obstruction. Consistency between CT and bronchoscopy results was analyzed. Receiver operating characteristic (ROC) curves assessed the diagnostic performance of CT features and D-dimer. Univariate analysis revealed significant differences between the two groups in age, lymphocyte count, lymphocyte percentage, C-reactive protein (CRP), D-dimer, peak body temperature, bronchial obstruction, bronchiolitis, and lung consolidation (all P < 0.05). Multivariate analysis identified elevated D-dimer (P = 0.050, OR = 2.048, 95% CI: 1.000-4.195) as an independent risk factor, and bronchial obstruction on CT(P < 0.001, OR = 31.339, 95% CI: 9.922-98.985) as a strong independent predictor for the presence of bronchial mucus plugs. ROC analysis: Bronchial obstruction: AUC = 0.838 (sensitivity: 79.6%, specificity: 87.9%, PPV: 72.9%, NPV: 91.3%). D-dimer: AUC = 0.692 (sensitivity: 56.6%, specificity: 81.7%). lung Consolidation: AUC = 0.643 (sensitivity: 57.4%, specificity: 73.8%). Elevated D-dimer is an independent risk factor, while bronchial obstruction on thin-section CT is a reliable predictive imaging marker for bronchial mucus plugs in pediatric MPP. Bronchial obstruction on CT offers high diagnostic accuracy, especially with its strong specificity and negative predictive value, supporting its role as a non-invasive tool to guide clinical decisions.

Spinal muscular atrophy (SMA) is a monogenic neuromuscular disorder caused by SMN1 gene deletion and classified by clinical severity. The objective of this study was to evaluate the genotypic and phenotypic spectrum in SMA in Bangladeshi children.This cross-sectional prospective study was conducted in Pediatric Neurology Department, National Institute of Neurosciences and Hospital of Bangladesh from January 2019 and December 2022. A total of sixty four cases with clinically suspected SMA were enrolled. Genetic confirmation was done using MLPA.Genetic confirmation was achieved in 48 (75%) patients. Homozygous deletion of SMN1 exons 7 and 8 was detected in 44 (68.75%) cases, while isolated exon 7 deletion was found in 4 (6.25%) cases. No deletion was identified in 16 (25%) cases. Among genetically confirmed patients, SMA type I was most common (54%), followed by type II (40%) and type III (6%). The mean age of onset was significantly earlier in SMA type I compared with types II and III (p < 0.05). A significant inverse correlation was observed between SMN2 copy number and disease severity (Spearman's rho = 0.825, p < 0.001). Most type I patients had two SMN2 copies, whereas type II and III patients predominantly had three or more copies. Respiratory complications and mortality were predominantly in type I patients. Two patients received risdiplam and two underwent gene replacement therapy (onasemnogene abeparvovec).In conclusion, A significant genotype-phenotype correlation exists between SMN2 copy number and clinical severity among Bangladeshi children with SMA. Limited access to disease-modifying therapy highlights the need for early diagnosis and improved treatment accessibility in resource-limited settings.

The severity and incidence of invasive pneumococcal infections increase in inborn errors of immunities. However, there are limited number of studies in the literature evaluating pneumococcal antibody levels in patients with a prediagnosis of transient hypogammaglobulinaemia (THI) and unclassified hypogammaglobulinemia (UH). The aim of our study was to serologically evaluate pneumococcal antibody levels in children aged 24-72 months with THI or UH who had completed the primary PCV schedule, and to compare these levels with those of age matched healthy control. Patients aged between 24-72 months who were admitted to the Pediatric Immunology Allergy Department Outpatient Clinic between January 2024 and July 2024 and who were considered to have transient or unclassifiable hypogammaglobulinaemia. Healthy children of similar age group, without signs of infection or chronic disease and with complete vaccination according to their age were included in the study as a healthy control group. Serum samples obtained were separated and stored at -20 C⁰ until the day anti-PNP IgG levels were studied by ELISA method. No statistically significant difference was found when anti-PCP IgG levels were compared according to the diagnosis of THI and UH in the patient group (p=0.410). It was determined that both patient groups produced similar antibody levels. There were no statistically significant differences in anti PCP IgG levels between patients and control group (p=0.427). When the correlation between the time elapsed since the last dose of PCV13 and anti-PCP IgG levels was evaluated in the patient group (both in all patients and age groups) and in the control group, no statistically significant correlation was found. In the patient group, anti-PNP IgG levels were found to be lower in the group in which both IgG and IgM values were low compared to the other groups. No statistically significant difference was found between the clinical characteristics of the patients and anti-PCP IgG levels. In conclusion, this study is one of the few to evaluate pneumococcal antibody levels in children with THI and UH who have completed the primary PCV13 vaccination series. Further prospective studies involving serotype-specific tests and different pneumococcal vaccine formulations are needed.

Nurse-led Buteyko versus diaphragmatic breathing retraining in hospitalized children with asthma: A three-group quasi-experimental study.

Primary central nervous system lymphoma: A thirteen-year experience of a pediatric hematology and oncology department in Casablanca

Child maltreatment recognition and reporting attitudes among pediatric nurses and physicians in Türkiye: A cross-sectional comparative study.

The presentation of dengue as infectious myositis is considered an atypical and often underrecognized manifestation. This study aimed to characterize the clinical features and outcomes of pediatric patients diagnosed with dengue-associated infectious myositis, to delineate their sociodemographic profiles at the time of diagnosis, and to evaluate their laboratory findings and clinical outcomes. The authors conducted a retrospective observational study in the pediatric department of a tertiary care hospital in the state of Bahia, Brazil, including patients up to 14 years who were admitted with clinical features of infectious myositis and laboratory-confirmed dengue infection between January 2022 and July 2024. Sociodemographic characteristics, clinical manifestations, laboratory parameters and outcomes were analyzed. Data from 176 patients were analyzed. A higher incidence was observed among male patients (68.8%), with most cases occurring during the winter season (56.25%). The mean age was 9.25 ± 3.22 years. Fever was the most frequent symptom (96%), followed by myalgia (89.2%). Calf pain was reported in 69.3% of cases. Regarding creatine phosphokinase (CK) levels, 46% of patients had values between 1000-5000 U/L, while 17% presented with CK > 5000 U/L at admission. None of the patients developed acute kidney injury or died. Dengue-associated myositis exhibited a benign clinical course in this symptomatic pediatric cohort. However, these findings suggest that clinical and laboratory parameters may support a risk-based clinical approach to patient monitoring and management; prospective studies are needed to validate risk stratification strategies.