Abstract This study proposes a novel multi-scale numerical method for thermal-mechanical analysis of mini-channel heat exchangers (MCHEs) under internal fluid pressure and temperature loads. The method comprises a macro-scale model for global analysis and a meso-scale model for detailed submodel analysis, specifically focusing on the internal fluid pressure effects within the MCHEs. The macroscopic model divides the MCHE into cover plate and homogenized regions subjected to pressure and temperature loads. To incorporate internal pressures into the homogenized MCHE model, mathematical equations are formulated to convert internal fluid pressures into equivalent strain loads. Additionally, a novel equivalent thermal expansion method is introduced, integrating internal fluid pressure loads by prescribing equivalent thermal expansion coefficients alongside spatially-varying nodal temperature fields within the MCHE. The meso-scale models with detailed channel patterns are assigned to specific portions of the homogenized region. The integration of the mesoscale model into the macroscopic framework is achieved through the application of the submodel method. Comparisons between the equivalent and actual MCHE models show that the proposed equivalent method can provide accurate predictions for thermal-mechanical deformations and stresses, and significantly reduce the computational expenses.
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