Mining online peer support communities to understand treatment side effects in Multiple Sclerosis.

Evidence-based, patient-centred management of tooth wear: 15-years insights from the Radboud Tooth Wear Project.

Prostate magnetic resonance imaging (MRI) has become a crucial tool in diagnosing and managing prostate cancer, mainly by helping to avoid unnecessary biopsies and enhancing the detection of clinically significant disease. However, its clinical usefulness is often limited by wide variation in how images are acquired, interpreted, and reported worldwide. This inconsistency affects diagnostic accuracy and patient outcomes. In response, the Quality Improvement Subgroup of the European Society of Urogenital Radiology (ESUR) Prostate MRI Working Group has created a practical, three-step quality-improvement framework aimed at standardising and improving prostate MRI practices. This framework consists of: Step 1: 'Build it right', establishing a foundation of technical excellence through adherence to the Prostate Imaging Reporting and Data System (PI-RADS) technical standards, objective quality assessment using the Prostate Imaging Quality (PI-QUAL) score, and systematic artefact reduction. Step 2: 'See it right', emphasising interpretive excellence via structured training, institutional quality assurance metrics, and multidisciplinary collaboration. Step 3: 'Improve and innovate', promoting continual refinement through emerging technologies such as AI-driven assessment, deep learning reconstruction, and remote supervision. By incorporating this structured approach into daily practice, this framework aims to ensure that prostate MRI consistently fulfils its promise of accurate, reproducible, and patient-centred care. A coordinated effort towards international implementation, benchmarking, and outcome-based validation represents the next critical step to maximise global impact. KEY POINTS: Question Wide variation in prostate MRI acquisition, image quality, and reporting undermines diagnostic accuracy. A structured roadmap is needed to ensure consistent quality and reproducible practice. Findings The ESUR Prostate MRI Working Group outlines a three-step framework-'Build it right', 'See it right', 'Improve and innovate'-to standardise acquisition, interpretation, and quality assurance. Clinical relevance Applying this roadmap in clinical practice aims to enhance diagnostic confidence and promote consistent, high-quality prostate cancer care across diverse healthcare settings.

Paediatric patient experience during hospitalisation stays: Developing paediatric PREMS questionnaires through a collaborative Delphi study.

Evaluating quality of life in thoracic malignancy trials: A scoping review on ESMO-MCBS quality of life checklist adherence and concordance with progression-free and overall survival.

Technology-Enabled Crisis Care for Youth: Bridging the Gap.

Perspectives from opioid treatment program staff on community pharmacy-based methadone dispensing in North Carolina.

The current kidney care model - focused on late-stage disease and in-center hemodialysis - is unsustainable, because of costs, environmental burden, poor outcomes, and reduced quality of life. The 78th World Health Assembly's recognition of kidney disease as a serious health threat presents a critical opportunity to reshape kidney care. Aligned with this, the 2026 World Kidney Day theme, "Kidney Health for All: Caring for People, Protecting the Planet", calls for a systematic change. A sustainable model must prioritize early detection and prevention, reducing the need for kidney replacement therapy. Transplantation and home dialysis benefit people with kidney failure, environment and society. Dialysis itself must become more eco-friendly without compromising care quality, recognizing that planetary perturbations in turn affect kidney health. Conservative care should also be considered, particularly for elderly and frail patients, if the quality-of-life benefits outweigh the perspectives offered by dialysis. Achieving this shift requires coordinated action across all stakeholders; education and engagement of the public, policy makers and health professionals to raise awareness about the threat of kidney disease; and an urgent move toward patient-centered care.

The Fastest NICU Genome is One Completed (or at Least Coordinated) Prenatally: A Joint Perspective From United States-Based Maternal-Fetal Medicine and Neonatologist-Geneticists.

In December 2024, the US Department of Veterans Affairs (VA) and the US Department of Defense (DoD) released a joint update of their 2017 clinical practice guideline (CPG) for the rehabilitation of individuals with lower limb amputation (LLA). This synopsis highlights the key aspects of the guideline development process and describes the CPG recommendations. The VA/DoD Evidence-Based Practice Work Group convened a joint VA/DoD guideline development work group (WG) that included clinical stakeholders and conformed to the Institute of Medicine's tenets for trustworthy clinical practice guidelines. The guideline WG conducted a patient focus group, developed key questions, and systematically searched and evaluated the literature from a 8 year time frame (English-language publications from July 6, 2016 to March 15, 2024). The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system was utilized to evaluate the evidence and formulate recommendations. The WG developed 26 recommendations along with algorithms and supplemental materials to guide providers in providing evidence-based, interdisciplinary, patient-centered care through all phases of LLA rehabilitation. The CPG was reviewed by stakeholders outside the WG before approval by the VA/DoD Evidence-Based Practice WG. This article summarizes key features of the guideline to help clinicians utilize the CPG to support patient-centered care.

Recent advancements of neoadjuvant strategies in locally advanced rectal cancer.

Advancing Pharmacy Students' Competence in Transgender Health: Multicohort Evaluation of a Gender-Affirming Therapy Curriculum.

Chronic heart failure (CHF) is a complex and often progressive condition, requiring ongoing self-management and lifestyle adjustments. Empowerment, which refers to a person's ability to oversee their health and be more involved in their care, serves as the foundation of this engagement, and health coaching has emerged as a critical strategy to help patients take an active role and manage their condition effectively. This study aimed to evaluate the five RE-AIM elements-reach, effectiveness, adoption, implementation, and maintenance-of a health coaching program (H-Coaching) in empowering hospitalized patients with CHF. An exploratory study was conducted involving 55 patients admitted to the cardiology unit of a university hospital in northern Spain, who were divided into a preintervention group (n = 25) and a postintervention group (n = 30). The intervention involved the implementation by nurses of H-Coaching to empower patients with CHF during their stay and prepare them for discharge. To measure CHF patient empowerment, the Spanish adaptation and validated version of the Patient Empowerment in Long-Term Conditions questionnaire was used. This tool assesses empowerment across three dimensions (positive attitude and sense of control, shared and informed decision-making, and information seeking and peer sharing) and was administered at two time points: before (T1) and after (T2) the intervention. The difference between pre- and postintervention empowerment scores was statistically significant for the positive attitude and sense of control dimension, with a mean improvement of 0.58. Furthermore, a statistically significant difference was observed for item 33, "I need to know what is happening to me and why," within the shared and informed decision-making dimension. No statistically significant difference was observed for item 35, "I have shared my knowledge about my illness with people who have similar illnesses to mine," within the information-seeking and peer-sharing dimension, although a mean improvement of 0.56 between pre- and postintervention scores was observed. The results of this study indicate that health coaching is effective in empowering patients with CHF in hospital settings. Furthermore, several factors were identified that can help ensure the successful implementation and evaluation of health coaching, such as nurse training and professional experience, a supportive environment, and active caregiver involvement. This knowledge can be used to design future interventions to empower hospitalized patients with CHF in other settings.

As humanity's marked effects on Earth's natural systems become increasingly apparent, we witness with alarm the impact on health and healthcare delivery. In this review, interrelationships between climate change, kidney health, and peritoneal dialysis (PD) therapies are described, and expansion of duty of care to the environment while maintaining the highest-quality healthcare is explored. Practical, high-yield actions that can be undertaken by patients and providers through the principles of sustainable care are introduced, including medication and single-use plastic consumables optimization, incremental PD, remote health monitoring, innovative PD effluent drainage, waste optimization, and importantly, patient empowerment as partners in sustainability. To ensure sustainable practices are embedded in clinical care, creation of a network of green champions, alignment with low carbon sustainable health systems more broadly, and appropriate uptake of emerging innovations in PD therapy that may be offered through sustainable procurement and regional or point of care dialysate production are crucial.

Patient with pluripathology-centered care: The patients' voice and the professionals' vision

The United States is a diverse nation, with over 22% of the population speaking a language other than English at home. Barriers and care disparities persist for orthopaedic patients with a non-English preferred language, particularly for those treated in language-discordant settings. The purpose of this study was to assess the linguistic diversity of orthopaedic surgeons and evaluate this relative to census-level linguistic diversity. This cross-sectional observational study analyzed the American Academy of Orthopaedic Surgeons database to assess surgeon language diversity. Data on state, subspecialty, and language(s) spoken were extracted for all surgeons listed. Descriptive statistics were used to evaluate linguistic diversity among surgeons. Differences between surgeon-level and population-level linguistic diversity were quantified using residuals from an expected 1:1 representation, reflecting ideal language concordance. Among the 19,505 orthopaedic surgeons registered in the database, 1,615 (8.28%) spoke at least one language aside from English, with 172 (0.88%) speaking three or more languages. Spanish (61.55%), French (20.87%), and German (12.07%) were the most common second languages. Pediatrics (7.77%) and spine (5.67%) had the highest percentage of multilingual surgeons, while trauma (3.70%) and musculoskeletal oncology (3.19%) had the lowest. Utah (16.59%), New Mexico (13.91%), Florida (12.46%), and Arizona (12.11%) had the highest proportions of multilingual surgeons. In 39 of 50 states, the proportion of Spanish-speaking surgeons is lower than that of Spanish speakers in the population, with the greatest discrepancies in California, Texas, and New Mexico. This study highlights linguistic disparities between patients and orthopaedic surgeons, indicating gaps that may contribute to language-discordant care and reliance on interpreters. Additional assessment of opportunities to increase multilingual representation and care capabilities across health systems is essential to ensure patient-centered and equitable care.

Glaucoma is a progressive, irreversible optic neuropathy that leads to the loss of retinal ganglion cells, vision loss, and blindness. Elevated intraocular pressure (IOP) is the only modifiable risk factor, and topical hypotensive eye drops remain the mainstay of treatment, reducing disease progression by up to 60%. However, patient adherence to therapy remains a significant challenge since this disease is usually asymptomatic in its early stages. Patient preferences and individual characteristics play a key role in adherence. This study aimed to obtain further knowledge about patient preferences regarding glaucoma treatment to better understand factors influencing adherence. A cross-sectional, multicenter survey was conducted in Spain between March and December 2024 among patients with glaucoma receiving topical treatment for more than 6 months. A questionnaire was designed to collect patients' information about their beliefs, preferences, and adherence-related factors. Of 200 participants, 169 valid responses were analyzed. Most patients were aged 51-74years, 60.2% were women, and 71.2% had been on treatment for more than 12months. Although 93.5% recognized the importance of preservatives, only 36.0% reported having received information about them from their ophthalmologist. Preferences between multidose bottles (MDBs, 42.2%) and single-dose units (SDUs, 37.0%) were similar, although younger women (18-30years) showed a preference for SDUs (p < 0.05). Perceived ease of handling was strongly influenced by prior experience. Most patients considered SDUs as more hygienic, whereas MDBs were perceived as more environmentally friendly; nearly 79% valued ecological impact. Self-reported adherence to therapy was moderate, with 57.6% of participants denying missed doses. Nonadherent patients were more likely to favor reminder systems (74.5%, p = 0.029). Treatment efficacy was ranked as the most important factor, followed by side effects, ease of use, cost, and environmental impact. This study highlights substantial variability in patient preferences and underscores the importance of personalized, patient-centered glaucoma care. Enhanced education on preservatives, improved communication, and sustainable packaging could improve adherence and satisfaction. Larger multicenter studies are needed to confirm these findings and inform long-term adherence strategies.

IntroductionThe advent of tyrosine kinase inhibitors (TKI) has revolutionised the treatment of chronic myeloid leukaemia (CML). Nevertheless, no specific tools are currently available to support follow-up and guarantee the adequate management of safety, adherence, and effectiveness altogether of TKI-based regimens. This study aimed to introduce a monitoring instrument tailored to patients undergoing TKI therapy for CML.Data SourceA structured instrument proposal was developed after conducting an integrative review. The instrument was then evaluated by clinicians and laboratory professionals with expertise in onco-haematology, who assessed clarity, objectivity, practicality, and clinical relevance using a five-point Likert scale.Data SummaryThe model comprised three protocols designed to evaluate adherence, safety, and effectiveness of TKI therapy. During evaluation of the instrument, all assessed parameters achieved mean scores ≥ 3.0. By aligning with international guidelines, the instrument consolidates essential monitoring parameters, thereby enhancing clinical decision-making and supporting patient-centred care in CML.ConclusionInstruments of this nature are rare and represent an important challenge for healthcare teams managing CML patients. Considering that adherence and safety are critical determinants of therapeutic success, structured tools such as this have the potential to facilitate improved outcomes.

Utopian or dystopian? A mixed-methods study of nursing and midwifery students' perceptions of artificial intelligence and robot-assisted person-centred care in education.

Understanding factors impacting quality of life in patients with keratinocyte carcinoma: A cross-sectional analysis of Mohs surgery patients.