The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2025 annual meeting, held in Bogotá, Colombia, featured soapbox presentations highlighting innovative approaches to psoriatic disease (PsD) care. Dr. Vasileios Charisis presented the Psoriatic Arthritis Inflammation Explained Through Multi-Source Data Analysis Guiding a Novel Personalised Digital Care Ecosystem (iPROLEPSIS) project, which applies digital phenotyping and explainable artificial intelligence to monitor psoriatic arthritis (PsA) using smartphone-based typing dynamics and hand motion tracking. Pilot data demonstrated high accuracy in detecting functional impairments, underscoring the potential of digital biomarkers for personalized disease management. Dr. Rodrigo García-Salinas reported consensus recommendations from the Red de Excelenciaen Artritis para la América Latina-Pan American League of Associations for Rheumatology (REAL-PANLAR) group to establish PsD Centers of Excellence (CoEs) in Latin America. Through a Delphi process, experts from 12 countries defined structural, process, and outcome standards, resulting in 2 adaptable models-optimal and model-designed to reduce diagnostic delays, enhance multidisciplinary collaboration, and improve outcomes. Dr. Juan Raul Castro-Ayarza summarized real-world evidence on biologic drug survival in Latin America, emphasizing fragmented data and variability across national cohorts. Findings from Venezuela, Brazil, Argentina, and Colombia revealed differences in treatment persistence and predictors of discontinuation, reinforcing the need for a standardized regional registry. Collectively, these initiatives demonstrate the value of digital health tools, region-specific care frameworks, and real-world evidence in advancing PsD management globally.

MEYER project: Towards a national protocol for in vivo measurement of 131I in the thyroid of exposed populations in emergencies.

ABSTRACT Since the beginning of the twenty-first century, significant legislative action has been taken to address human trafficking around the world. From the United Nations Trafficking Protocol to the Trafficking Victims Protection Act in the United States, countries around the world took the initiative in contributing to the global fight to end trafficking in persons. What has remained underexplored is how countries define human trafficking. In 2007, Mexico passed its first anti-trafficking law to federally criminalize trafficking in persons. Five years later, the Mexican government revamped these efforts by passing Ley General para Prevenir, Sancionar y Erradicar los Delitos en Materia de Trata de Personas y para la Protección y Asistencia a las Víctimas de estos Delitos, which has undergone several reforms to date. However, nearly two decades later, Ley General’s definition of human trafficking remains inconsistent with the widely endorsed international definition of human trafficking. The following paper examines the legal progression of Mexico’s human trafficking law, Ley General, and offers recommendations for future anti-trafficking legal reform.

Type of the article: Research ArticleAbstractDigital transformation is central to customs modernization, yet empirical evidence on how regulatory digitization translates into employees’ job proficiency through capability-building remains limited in Peru. This study aims to test the relationships among digital customs regulations, digital transformation, professional competencies, and job proficiency in Peruvian customs agencies, including the mediating role of professional competencies, using PLS-SEM. A quantitative explanatory–predictive, cross-sectional design was applied. Data were collected via a five-point online survey of 104 employees in Peruvian customs agencies (Lima–Callao) in October–November 2025, recruited through WhatsApp-based convenience/snowball sampling. The model was estimated in ADANCO 2.4.1 with a two-stage approach for the higher-order digital transformation construct and bootstrap inference. Digital customs regulations strongly predicted digital transformation (β = 0.872, p < 0.001) and generated a sizeable total indirect effect on job proficiency (β = 0.757, p < 0.001). Digital transformation increased professional competencies (β = 0.853, p < 0.001) and had a direct effect on job proficiency (β = 0.464, p = 0.026), while professional competencies also enhanced job proficiency (β = 0.473, p = 0.023). Mediation was supported for the pathway digital transformation → competencies → job proficiency (β_ind = 0.403, p = 0.034), yielding a total digital transformation effect of β = 0.867. Explanatory power was high (R²: DT = 0.761; competencies = 0.725; job proficiency = 0.814; SRMR = 0.041). The findings indicate that regulatory-driven digitization improves work proficiency primarily when accompanied by systematic competency development, highlighting training and institutional enablers as priorities in customs reform.AcknowledgmentsA la Dirección de Investigación de la Universidad Peruana de Ciencias Aplicadas por el apoyo brindado para la realización de este trabajo de investigación a través del incentivo UPC-EXPOST-2026-1. [We would like to thank the Research Directorate of the Universidad Peruana de Ciencias Aplicadas for their support in carrying out this research through the UPC-EXPOST-2026-1 grant.]

The global question of how to identify, develop and assess mathematical knowledge that is relevant to future secondary school teachers, has been central in the emergence of mathematics education research from early on. We review parts of this history from the viewpoint of the anthropological theory of the didactic, and in particular the notion of relationships to mathematical praxeologies that are held by certain positions within school and university institutions. We also consider a modern case, where the questions arise in a very practical sense: how to bridge the gap between standard undergraduate mathematics courses and a school relevant model of real numbers and functions? We show how both theoretical and practical aspects of this more local question arise in a so-called capstone course for students with about two years of undergraduate mathematics experience. La cuestión global de cómo identificar, desarrollar y evaluar el conocimiento matemático que es relevante para futuros profesores de secundaria ha sido central en la emergencia de la investigación en educación matemática desde sus inicios. Revisamos partes de esta historia desde el punto de vista de la teoría antropológica de lo didáctico, y en particular la noción de relaciones con las praxeologías matemáticas que son sostenidas por ciertas posiciones dentro de las instituciones escolares y universitarias. También consideramos un caso moderno, donde las preguntas surgen de manera muy práctica: ¿cómo cerrar la brecha entre los cursos de matemáticas de pregrado estándar y un modelo de números reales y funciones relevante para la escuela? Mostramos cómo tanto los aspectos teóricos como prácticos de esta cuestión más local surgen en un curso de culminación para estudiantes con aproximadamente dos años de experiencia en matemáticas de pregrado. La question globale d’identifier, développer et évaluer les connaissances mathématiques qui sont pertinentes pour les futurs enseignants du secondaire, a été depuis les débuts un levier central dans l’émergence de recherches en didactique des mathématiques. Nous exposons des éléments historiques de cette question du point de vue de la théorie anthropologique du didactique, et en particulier la notion de rapport aux praxéologies mathématiques entretenu par certaines positions au sein des institutions scolaires et universitaires. Nous examinons aussi un cas moderne où ces questions apparaissent d’une manière plus pratique : comment combler le fossé entre une licence générale en mathématiques et des conceptions des nombres réels et des fonctions d’une variable réelle qui sera pertinente pour l’enseignement secondaire ? Nous montrons comment les aspects théoriques et pratiques de cette question plus locale apparaissent dans un cours de synthèse pour des futurs enseignants, qui ont passé deux ans de cours mathématiques universitaires.

Sintering behavior and microwave dielectric properties of 0.6Zn2−SiO4− (0.2 ≤x≤ 0.65)–0.4Zn0.17Nb0.33Ti0.5O2 ceramics with near-zero temperature coefficient of resonant frequency

This article examines the impact of two boarding schools for the indigenous population in an attempt to castilianize and incorporate Tseltal and Tsotsil people from the Highlands of Chiapas into the national culture. It analyzes the establishment, organization, material conditions, financing, and curriculum of the Escuela de Experimentación para Indígenas (Experimentation School for Indigenous People) and the Escuela para la Regeneración de la Raza Indígena (School for the Regeneration of the Indigenous Race), which were founded in 1918 in San Andrés Chamula and San Cristóbal de Las Casas, respectively. Both schools constituted some of the first experiments in Chiapas, and probably in Mexico, that sought to create educational spaces exclusively for indigenous people during the post-revolutionary years. Despite the attempts, the scarcity of resources among the indigenous population made it difficult to pay the taxes necessary for educational financing, causing the project to fail.

Honduras and El Salvador had two of the most stable party systems in Latin America. In recent years, however, their party systems have experienced drastic change. This article argues that elite-driven polarisation, in its ideological and affective forms, has propelled that transformation. More specifically, I contend that Honduras’s Manuel Zelaya and El Salvador’s Nayib Bukele used polarisation as a deliberate strategy to mobilise support as they vied for political power. In Honduras, Zelaya’s shocking left-wing turn and the 2009 coup that overthrew him sparked ideological polarisation. Upon returning from exile, Zelaya’s left-wing party, Libertad y Refundación, used affective polarisation to build a big-tent coalition to win elections. As a result, the country realigned from a non-polarised two-party system to a polarised multiparty system. In El Salvador, Nayib Bukele deployed affective polarisation as a strategy to take on the party system dominated by the Alianza Republicana Nacionalista (ARENA) and Frente Farabundo Martí para la Liberación Nacional (FMLN). Bukele’s use of affective polarisation spelled the death sentence of traditional parties, and the party system collapsed. After taking office, Bukele doubled down on that strategy – while also relying on ideological cues – to boost his popularity and strengthen his grip on power. The key takeaway is that elite-driven polarisation can abruptly disrupt party systems – even those that seem most stable.

This article examines the outcomes of COIL en Clave ODS para la Educación Superior en Iberoamérica, a five-week online training program developed by STAR Argentina to equip higher education professionals across Latin America, the Caribbean, and Spain with the tools to integrate global citizenship and the Sustainable Development Goals (SDGs) into Collaborative Online International Learning (COIL) initiatives. The program employed a flipped classroom model combined with live, interactive sessions to foster intercultural collaboration and sustainability-oriented pedagogy through active and participatory learning strategies. The analysis of post-program survey responses and reflections indicates successful integration of content and a significant increase in participants’ confidence in designing intercultural, SDG-aligned COIL projects, thereby highlighting COIL as a potentially scalable strategy that supports educators in designing learning environments in which international students are positioned as active contributors to sustainability-oriented learning.

This study evaluated the effectiveness of the therapeutic game Creciendo en Mindfulness (Growing in Mindfulness, CEM) in reducing emotional and behavioral problems among adolescents confined in the “Jalteva” Pedagogical Internment Center in Honduras. A one-group, pre-experimental pretest–posttest design was employed (n = 27; ages 13–18). Before and after four CEM sessions, participants completed the Cuestionario para la Evaluación de Problemas en Adolescentes (Questionnaire for the Assessment of Adolescent Problems, Q-PAD) and the Personality Assessment Inventory–Adolescent (PAI-A). Changes were analyzed using the Wilcoxon signed-rank test, and effect sizes were calculated with Hedges’ g. After the intervention, uncertainty about the future decreased from the 86th to the 71st percentile (p = .011; g = −0.46), and perceived lack of social support declined from T = 64 to 58 (p = .032; g = −0.45). However, aggressive attitude increased from T = 55 to 58 (p = .037; g = 0.28). The correlation pattern among scales became more coherent, suggesting greater emotional awareness. The findings suggest that CEM yielded specific improvements in internal variables related to anticipatory anxiety and perceived support, though its overall impact on emotional and behavioral symptomatology was limited. Institutional constraints, the absence of a control group, and the short follow-up period restrict causal attribution and generalizability. It is recommended to complement the program with individualized interventions and family involvement to enhance adolescents’ social reintegration.

The Rayen Lafken (Flowers of the Sea) association is a group of women who identify as Lafkenche and collect and process the edible algae, Durvillaea antarctica, or kolloy in the vernacular, an alga that forms large, submerged forests containing important biodiversity. This article, a collaborative work, analyzes the activity and development of the organization under the framework of expanded care economies developed in an Indigenous context. It illustrates how work and family networks address the social organization of family care, the expanded care of the coast and its submerged forests, as well as the constantly threatened culture itself. This occurs in a process that is empowering to the women that carry out the work and to their communities in the context of territorial recovery. In addition, the organization deploys material and sociocultural practices relevant and scalable for the territorial care of the kolloy and the sea as commons. La Rayen Lafken (Flores del mar) es una agrupación de mujeres de identidad lafkenche que recolectan y procesan el alga comestible Durvillaea antarctica, kolloy en idioma vernáculo; alga que conforma grandes bosques sumergidos de importante biodiversidad. El documento, fruto de un trabajo colaborativo, analiza la actividad y desarrollo de la organización bajo las preguntas de las economías ampliadas de cuidado desarrolladas en contexto indígena. Muestra, como el trabajo y la red familiar abordan la organización social del cuidado familiar, el cuidado ampliado del bordemar y sus bosques sumergidos, como también, de la propia cultura constantemente amenazada. Ello en un proceso que resulta ser empoderador para las mujeres que las realizan y para sus comunidades en el marco de recuperación territorial. Asímismo, la organización despliega prácticas materiales y socioculturales pertinentes y escalables para el cuidado territorial del kolloy y del mar como comunes.

IntroductionIntravenous fluids are essential components of perioperative care, supporting intravascular volume, acid–base balance and electrolyte homeostasis. Despite extensive research in adult surgical populations, paediatric-specific evidence remains limited, and clinical practice frequently relies on extrapolated adult-based recommendations. This gap is particularly relevant in paediatric non-cardiac surgery, where fluid choice may influence key physiological outcomes such as acid–base status, electrolyte balance, renal function and haemodynamic stability. Given the heterogeneity of study designs, perioperative phases, age groups and reported outcomes in the paediatric literature, a comprehensive synthesis of the existing evidence is needed before a systematic review can be undertaken.Methods and analysisWe will conduct this scoping review following the methodological guidance of the Joanna Briggs Institute Manual for Evidence Synthesis, and the reporting will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guideline.This scoping review will map existing evidence on perioperative intravenous fluid management in paediatric patients (<18 years) undergoing elective non-cardiac surgery in outpatient and inpatient settings. Eligible study designs will include randomised trials, observational studies and systematic reviews. A comprehensive search will be developed with a medical librarian and applied to MEDLINE (PubMed), Ovid, Embase, Web of Science, CENTRAL, Google Scholar and ClinicalTrials.gov, with no date restrictions and limited to English, Spanish and German.Eligibility is framed using participants, concept and context: paediatric patients (<18 years) undergoing non-cardiac surgery; concepts related to preoperative fasting/replacement period, intraoperative period and postoperative period up to 24 hours, intravenous fluid management for maintenance/replacement; and hospital/outpatient surgical settings. Study selection and data charting will follow established scoping review methodology. Data will be synthesised descriptively using narrative and tabular formats. No meta-analysis or formal risk-of-bias appraisal is planned, consistent with scoping review methodology.Ethics and disseminationThis scoping review involves no primary data collection and relies exclusively on published literature; therefore, formal ethical approval is not required. The protocol received administrative approval from the Comité de Ética para la Investigación Científica of Universidad del Cauca (approval no. 6553, 11 June 2025). Findings will be disseminated through peer-reviewed publications, conference presentations and targeted communication with paediatric anaesthesia and surgical communities.

108 - RENDIMIENTO DIAGNÓSTICO DE LOS CRITERIOS CLÍNICOS PARA LA IDENTIFICACIÓN DE CANDIDATOS A TRATAMIENTO FARMACOLÓGICO EN PACIENTES CON MASLD: IMPACTO DEL PERFIL METABÓLICO

LA ADIPOSIDAD CORPORAL COMO FACTOR DE RIESGO PARA LA TROMBOSIS DE LA VENA PORTA EN PACIENTES CON CIRROSIS HEPÁTICA

86 - ALTERNATIVA PREDICTIVA A LA ELASTOGRAFÍA POR RESONANCIA MAGNÉTICA: UN NUEVO BIOMARCADOR PARA LA EVALUACIÓN NO INVASIVA DE EHMET

Las Oralotecas están resurgiendo. A través de un proceso de investigación-creación, este texto es un espacio para la discusión de la memoria biocultural en Colombia, especialmente sus sonoridades. Nuevas formas de hacer y relacionarse con el mundo se encuentran en la diversidad del patrimonio biocultural, en un contexto de erosión de la biodiversidad y las culturas. Esto surge como una red de relaciones inherentes con el entorno socio-técnico. Basado en procesos de comunicación y apropiación social de la ciencia y la tecnología, se llevó a cabo una escuela de sensibilización sonora con colectivos de comunicación de los municipios de Tumaco, Guapi, Buenaventura y Nuqui, como medio para la sistematización de prácticas asociadas tanto a la biodiversidad como a la cultura de dos comunidades afrocolombianas del Pacífico colombiano. Así, a través de un proceso participativo de sonorización y creación ambiental, se realizaron visitas a los territorios costeros para la producción y postproducción de piezas artísticas denominadas “Postales Sonoras” e ilustraciones, para divulgar el conocimientos ecológicos tradicionales. El proceso se sistematizó en una página web y se apoyó en el uso de mecanismos sonoros vinculados a los territorios. Como ejercicio exploratorio, la experiencia recoge nuevos elementos de la relación cultura-entorno-tecnología a través de prácticas de creación artística basadas en el lugar. En conclusión, es necesario problematizar el papel de las tecnologías y la creación artística para la difusión de la oralidad más allá de los procesos logocéntricos ligados a la comunicación hegemónica del conocimiento. Abstract The Oralotecas are resurging. Through a process of research-creation, this text is a space for the discussion of biocultural innovation in Colombia, especially its sonorities. New ways of doing and relating to the world are found in the diversity of biocultural heritage, in a context of erosion of biodiversity and cultures. This emerges as a network of inherent relationships with the socio-technical environment. Based on processes of popular communication and social appropriation of science and technology, a online school of sound sensitization was carried out with local communication collectives of Tumaco, Guapi, Buenaventura, and Nuqui municipalities, as a means for the systematization of practices based on fieldwork with both biodiversity and culture of two Afro-Colombian communities of the Colombian Pacific. Thus, through a participatory process of sound and environmental creation, visits were made to the coastal territories for the production and post-production of artistic pieces called “Sound Postcards” and illustrations, to disseminate the traditional ecological knowledge. The process was systematized on a web page and supported using sound mechanisms linked to the territories. As an exploratory exercise, the experience gathers new elements of the culture-environment-technology relationship through artistic creation practices based on the place. In conclusion, it is necessary to problematize the role of technologies and artistic creation for the dissemination of orality beyond the logocentric processes linked to the hegemonic communication of knowledge. Keywords: Biocultural innovation; Sound postcards; Pacific Litoral; Oraloteca; Art-technology

Emotional intelligence (EI) constitutes a central axis in adolescent development, particularly in technical educational contexts where pedagogical models centered on discipline and technical rationality prevail. Grounded in Mayer and Salovey’s four-branch model, this study analyzes qualitative gaps in EI influenced by environmental dynamics. The objective was to understand emotional development and identify the impact of the contextual ecosystem (school, family, and digital) on adolescents at the “Eleazar López Contreras” Industrial Technical School in San Cristóbal, Venezuela. The research adopted a qualitative approach with a systematic immersion ethnographic design. The purposive sample consisted of 18 key informants, distributed equally into three groups: 6 students (aged 12 to 17 with diverse academic performance), 6 teachers from technical and humanistic areas, and 6 legal guardians. Data collection included eight non-participant observation sessions in diverse natural settings; likewise, semi-structured interviews were conducted, recorded, and processed in their entirety. The systematic five-stage analysis led to the identification of five interconnected findings: centrally, a pattern of relational emotional dysfunction was revealed, originating from an absence of emotional linguistic mediation, which prevents adolescents from cognitively processing their internal states. Consequently, an expressive polarization oscillating between impulsivity and withdrawal is observed, a dynamic reinforced by ineffective coping via invalidating modeling by adults. In parallel, within the virtual environment, validation vulnerability emerged as a new risk scenario. It is concluded that the socio-educational ecosystem acts as an inhibitor of emotional development, deepening the diagnosed qualitative gaps through the rigidity of its dynamics. Given this diagnosis, the imperative need is raised to design and implement future proposals such as the “EQpados para la Vida” program, conceived as a systemic psychoeducational intervention to strengthen self-awareness and regulation within this educational ecosystem

BackgroundInfluenza viruses circulate year-round in Central America, but their impact on agricultural workers, essential to food security in the Americas, is poorly understood.MethodsWe evaluated the incidence of influenza among a cohort of agricultural workers in southwest Guatemala participating in active surveillance for influenza-like illness (ILI) from June 2020 to October 2024. Workers reporting cough, fever, or shortness of breath in the previous 7 days provided nasopharyngeal swabs for influenza RT-PCR testing using the Roche cobas liat instrument. Symptom data were collected on the day of reporting, day 7, and day 28, with differences in reported symptoms by influenza virus infection status assessed using Fisher’s Exact tests.ResultsOf 2,809 agricultural workers who participated in ≥1 year of surveillance, 76% were male with a mean age of 30 years. Overall, 400 (14%) ever reported an ILI episode; 7.3% (29/400) were influenza positive (flu+): 18 influenza A, 11 influenza B. The incidence of ILI and flu+ cases per 1000 person-weeks from 2021 to 2024 was 1.4 (95% Confidence Interval [CI] 1.3-1.6) and 0.11 (95% CI 0.07-0.16), respectively, with minimal yearly variation (Figure). Of the 400 ILI cases, 68% reported fever, 78% cough, and 28% shortness of breath. Flu+ cases reported fever more frequently than flu- cases (96.6% vs. 65.9%, p=0.001). Among ILI cases, 8.4% reported difficulty getting out of bed on day 7 and 3.4% on day 28, with no significant difference by influenza status.ConclusionAmong young adult, mostly male agricultural workers, 7.2% of reported ILI episodes were attributed to influenza, with fever being a key symptom. This study demonstrates the feasibility of monitoring circulating respiratory virus illnesses in field-based environments using active surveillance and rapid diagnostics.DisclosuresEdwin J. Asturias, MD, Pfizer: Grant/Research Support Molly Lamb, PhD, Merck: Grant/Research Support Daniel Olson, MD, Fundacion para la Salud Integral de los Guatemaltecos: Board Member|Merck: Grant/Research Support|Roche Diagnostics: Grant/Research Support

BackgroundZika virus (ZIKV), dengue virus (DENV) and chikungunya virus (CHIKV) are arboviruses transmitted by Aedes mosquitoes. While DENV serotypes 1 and 2 (DENV1 and DENV2) are the most prevalent in Guatemala, serotypes 3 and 4 (DENV3 and DENV4) have caused recent epidemics. In 2024, a public health emergency was declared by the Ministry of Health due to the rise in dengue cases. CHIKV and ZIKV outbreaks were reported between 2014-2017.Evolution of flavivirus serostatus among the AGRI cohort (2020-2022)The graph shows the serologic characteristics of the AGRI cohort against flavivirus infections. A rise in the multytipic DENV serostatus is observed over the years. On the contrary, there is a decline in the flavivirus-naive population.Density distribution of the MFI values against arbovirus-specific antigensThe MFI of the antigen-antibody reaction was recorded for each arbovirus. The evolution of cohort-level mean fluorescence intensity (MFI) readings over 3 years is shown. Positivity cutoffs are indicated by the dashed red line.MethodsMean Fluorescence Intensity (MFI) from anti-CHIKV/ZIKV/DENV1-4 antibodies was obtained using an IgG-based multiplex bead assay. Flavivirus-specific beads were coupled with the EDIII protein of ZIKV/DENV1-4. CHIKV beads were coupled with CHIKV E2 protein. We tested 1136 samples from 478 individuals, collected in 2020 (n=478), 2021 (n=338) and 2022 (n=320). A set of 15 samples from children born between 2018-2022 were used as regionally appropriate samples to calculate the positivity cutoffs (mean MFI + 3SD). A previously described algorithm for analyzing flavivirus MFI signals was used to discriminate between naive samples and primary/multitypic infections.ResultsCHIKV seropositivity was 56.9%, 51.5% and 53.4% for 2020, 2021 and 2022. During the follow up, 12 individuals had a negative-to-positive seroconversion against CHIKV. For 2020, 2021, and 2022, we detected seropositivity for primary infections of DENV1 (16.9%, 9.17%, 10.6%), DENV2 (9.41%, 21.0%, 11.2%), DENV3 (1.88%, 0.30%, 0.00%) and ZIKV (11.9%, 6.51%, 4.38%). Naïve-to-primary seroconversions were found for DENV1 in 2022 (n=12), for DENV2 in 2021 (n=14) and 2022 (n=10), and for ZIKV in 2021 (n=1) and 2022 (n=3). Flavivirus-naive prevalence went from 15.7% in 2020 to 7.8% in 2022.ConclusionThough confirmatory testing is needed, these findings suggest that active DENV1/2, ZIKV and CHIKV transmission was ongoing in the region for this period.DisclosuresBlair Weikel, MPH, Merck: Grant/Research Support Molly Lamb, PhD, Merck: Grant/Research Support Daniel Olson, MD, Fundacion para la Salud Integral de los Guatemaltecos: Board Member|Merck: Grant/Research Support|Roche Diagnostics: Grant/Research Support

Climate change and human activities threaten water resources in the Canary Islands, where increasing temperatures and decreasing precipitation intensify water stress. In order to develop strategies to protect water resources, it is necessary to know how water availability will evolve in this region. The Fundación para la Investigación del Clima (FICLIMA) methodology offers high-resolution projections (100 m × 100 m), which allow us to understand how climate change alters the long-term dynamics of the water balance in islands with complex orography and microclimates. The results reveal a decrease in the water balance due to increased evapotranspiration and stable or reduced precipitation. Severe decreases in the water balance are expected by the end of the century, reaching reductions of 50–75% on El Hierro or total depletion on Gran Canaria. Sustainable water management and the implementation of adaptive policies will be essential to guaranteeing water security in the future.