Overall Quality Of Life Research Articles

Combined microscopic and neuroendoscopic treatment effects on psychological and cognitive outcomes in ruptured intracranial aneurysms

BACKGROUND Intracranial aneurysms, characterized by focal arterial wall dilation, pose significant neurosurgical challenges due to their potential for rupture and hemorrhage, leading to severe clinical outcomes, including fatality. Patients often experience profound psychological and social impacts, such as depression, anxiety, and cognitive impairment, affecting their quality of life. Rapid progression and high mortality necessitate timely intervention. Advances in neurosurgical techniques, including microscopic surgery and neuroendoscopy, offer distinct advantages. Microscopic surgery provides precision and direct visualization, while neuroendoscopy ensures minimally invasive access and reduced tissue trauma. Integrating these methods optimizes treatment efficacy and clinical outcomes. AIM To evaluate the impact of combined microscopic and neuroendoscopic techniques on psychological, cognitive outcomes, and quality of life in patients with ruptured intracranial aneurysms. METHODS The study focused on 189 patients with intracranial aneurysm rupture and hemorrhage from January 2020 to May 2024 as the objects of observation and analysis. They were randomly divided into a control group (treated with simple microscope surgery, n = 94) and an observation group (treated with microscope combined with neuroendoscopy, n = 95). The treatment effects of the two groups were observed, mainly including depression and anxiety scale scores, cognitive function assessment results and quality of life assessment data. RESULTS Before treatment, the depression and anxiety scale scores, cognitive function assessment results and quality of life assessment data of the two groups of patients at different time points were compared, and there was no statistically significant difference (P > 0.05). After microscope combined with neuroendoscopy treatment, the study revealed that the observation group surpassed the control group in alleviating depression and anxiety, accelerating cognitive function recovery, and enhancing quality of life, with these differences being statistically significant (P < 0.05). CONCLUSION Surgical treatment combined with microscopy and neuroendoscopy has a significant positive effect on the mental health, cognitive function and overall quality of life of patients with intracranial aneurysm rupture and bleeding, can shorten the operation time and treatment time, and provides a new strategic reference for clinical treatment.

The Associations of Mindfulness and Self-Compassion on Quality of Life for Patients with Multiple Sclerosis, a Cross-Sectional Study from Turkey

Objective The aim of this study is to investigate the associations between self-compassion, mindfulness, emotional factors and multiple sclerosis (MS) related quality of life among the individuals with MS in Istanbul, Turkey. Results One hundred and thirteen MS patients participated in this cross-sectional study. In the linear regression model, older age, higher levels of disability, and higher anxiety levels significantly predicted lower MS related quality of life (p = .045, p = .023, p ≤ .001, respectively). Mindfulness component of the self-compassion scale significantly predicted better MS related quality of life (p = .007). The self-kindness and mindfulness subscale scores of the Self-Compassion Scale were positively and significantly correlated with the total scores of the Multiple Sclerosis International Quality of Life Questionnaire (r = .324, p = .003; r = .314, p = .003, respectively) Discussion These findings indicate that a high level of self-compassion and mindfulness has a positive impact on the quality of life in patients with multiple sclerosis. Considering these effects within social dimensions, such as family and friendship, may contribute to improving patients’ overall quality of life.

Nutritional guidance in spondyloarthritis: confronting the evidence gap.

to summarize current evidence on the role of specific dietary patterns in spondyloarthritis (SpA) management. dietary interventions may offer a novel, complementary strategy to manage symptoms and enhance overall quality of life in many rheumatic diseases, including SpA. Evidence suggests that the Mediterranean diet may have beneficial effects on inflammation and SpA symptoms. Although there is growing interest in the ketogenic diet with some promising results, data is scarce. Some SpA patients may have sensitivities or intolerances to certain foods containing gluten, which can trigger or worsen their symptoms, especially when associated with intestinal inflammation. Hypocaloric diets and weight loss can provide significant benefit in overweight and obese patients with SpA, potentially reducing systemic inflammation. Finally, while the efficacy of probiotics remains a matter of debate, periods of fasting have proven effective in reducing disease activity indices. the importance of a healthy dietary lifestyle and its potential benefits in symptom management is acknowledged by the majority of the patients. There is an increased need and demand from patients to receive nutritional counseling that should be integrated into routine SpA management to enhance patient outcomes.

Open-Source Versus Commercial Automated Insulin Delivery System for Type 1 Diabetes Management: A Prospective Observational Comparative Study from Canada.

Objective: This study compares unregulated open-source (OS) automated insulin delivery (AID) systems and commercial-AID (C-AID) systems regarding glucose management, patient-reported outcomes (PROs), and safety among adults with type 1 diabetes (T1D). Methods: We conducted a 12-week, prospective, observational, noninferiority, comparative, real-world study involving 78 adults with T1D and having used an AID system for ≥3 months (26 OS-AID and 52 C-AID users). A total of 4-week data from a blinded continuous glucose monitor was used to assess the effectiveness in glucose management (primary outcome: 24 h time in range [TIR%] for 4 weeks, with a noninferiority margin of 5%). Results: Our study suggested that OS-AIDs were noninferior to C-AIDs regarding the 24 h TIR% (78.3% [standard deviation or SD 11.0] vs. 71.2% [SD 10.9], mean difference 7.2% [95.08% confidence interval or CI: 1.9% to 12.5%], P < 0.001), even after adjusting for various confounding factors. OS-AIDs spent more time in hypoglycemia (<3.9 mmol/L) than C-AIDs (3.9% [SD 3.1] vs. 1.8% [SD 1.3], P < 0.001) yet within the recommended range. OS-AID users reported less fear of hypoglycemia, while other PRO measures (diabetes distress, hypoglycemia awareness, sleep, fear of hypoglycemia, treatment satisfaction, and overall quality of life) were not different between groups. No severe hypoglycemia or diabetic ketoacidosis was reported in either group, with a similar occurrence rate of technical issues during the 12-week study period. Conclusions: OS-AIDs are safe and noninferior to C-AIDs for TIR% among adults with T1D in real-world settings. Both OS-AID and C-AID systems can be considered for T1D management.

A Man’s Search for Meaning in Sex: Management of Compulsive Sexual Behaviour Disorder

The term compulsive sexual behaviour disorder (CSBD) involves a person’s excessive and recurring obsession with sexual fantasies, impulses and behaviours that are unpleasant for them and/or cause psychosocial harm. Due to the paucity of research on the topic, no specific guidelines are available for the treatment of CSBD, however, preliminary studies suggest a few options. This case report aims to discuss the management of a clinical case of CSBD that presented the increased number of sexual encounters with commercial sex workers leading to high-risk behaviours. After a detailed history and, physical and mental state examination, a diagnosis was established and management was done with a combination of pharmacotherapy and psychotherapy. A progressive improvement was noted over six months. The case report highlights the need for timely diagnosis and effective treatment, which can improve distress, dysfunction and overall quality of life.

Key Factors Influencing Outpatient Satisfaction in Chronic Disease Care: Insights from the 2023 Korea HSES

Background/Objectives: The outpatient healthcare experiences of patients with chronic diseases significantly impact disease management and quality of life. Patient satisfaction with healthcare services serves as a critical indicator of the responsiveness of healthcare systems and the advancement of patient-centered care. This study aimed to identify key factors influencing patient satisfaction and propose strategies for improvement. Methods: Using secondary data from the 2023 Healthcare Service Experience Survey (HSES), we analyzed patient satisfaction and its associated factors among respondents aged 15 years and older from households nationwide. Through multiple regression analysis and statistical testing, we examined the impact of the healthcare facility type, sociodemographic characteristics, and healthcare service experiences on satisfaction levels. Results: Information provided by physicians and nurses, communication with healthcare providers, and shared decision-making processes had a significant impact on patient satisfaction. Satisfaction levels were highest in hospitals and lowest in clinics. Older patients and those who discontinued treatment due to the financial burden reported lower satisfaction. Notably, information provided by nurses had the most substantial positive influence on satisfaction. Conclusions: Delivering patient-centered outpatient healthcare services is essential in improving satisfaction and health outcomes. Enhancing the service quality, reducing financial burdens, and adopting digital platforms to promote patient engagement are critical measures. These approaches will strengthen chronic disease management systems and contribute to improving the overall quality of life of the population. The entire study focused on outpatient care.

Integrating Palliative Care Consultation Into Inpatient Liver Transplant Evaluations: A Quality Improvement Study.

Palliative care (PC) consultation in high-risk patients with liver disease who are undergoing liver transplant (LT) evaluation is underused due to common beliefs that PC would negatively impact a patient's desire for transplant. This population is at risk due to high morbidity, mortality, and negative impact to overall quality of life. A 4-week pilot study was conducted in a transplant surgical intensive care unit at a single academic center to increase PC consultation during inpatient LT evaluation and improve transitions in care. Two Plan, Do, Study, Act quality improvement cycles were subsequently led by the PC nurse practitioner and social worker to increase the effectiveness of this intervention. The first cycle (November 29, 2018, to September 30, 2019) identified the need to increase PC education of intensive care unit nurses and promote interdisciplinary collaboration. The second cycle (October 1, 2019, to June 13, 2022) modified the study protocol to prioritize high-risk patients undergoing inpatient LT evaluation. Palliative care consultation increased by 262.5% from 2018 to 2019, with consults completed on 19% of all patients admitted for inpatient LT evaluations throughout the duration of the quality improvement study. Palliative care consultation on high-risk patients undergoing inpatient LT evaluation is a promising targeted strategy to increase utilization of PC in this population.

Healthy Diet Consumption Among Chronic Pain Populations: A Concept Analysis.

Healthy Diet Consumption Among Chronic Pain Populations: A Concept Analysis.

Exploring Alzheimer's Disease Treatment: Established Therapies and Novel Strategies for Future Care.

Exploring Alzheimer's Disease Treatment: Established Therapies and Novel Strategies for Future Care.

Features of anesthesiological support during mechanical thrombectomy: preoperative assessment and pain management strategies

Mechanical thrombectomy is acknowledged as one of the most effective treatments for acute ischemic stroke, as it facilitates the rapid restoration of blood flow to the affected brain regions. Timely execution of this procedure is critical for reducing neurological deficits and improving patient prognosis. In situations where the speed and precision of intervention can determine treatment success, the role of the anesthesiologist becomes indispensable. Anesthesiological support during mechanical thrombectomy not only ensures patient monitoring but also involves active participation in risk management throughout and after the procedure. Adherence to modern anesthesiological protocols not only increases the likelihood of successful outcomes but also allows for the adaptation of treatment to the specific needs of patients, particularly those with less favorable clinical indicators. In this context, it is essential not only to explore optimal anesthesia approaches but also to investigate the physiological factors influencing anesthesiological support. Furthermore, developing effective strategies for postoperative pain management is necessary. Raising awareness about these aspects will contribute to improving clinical outcomes, reducing the risk of complications, and enhancing the overall quality of life for patients following thrombectomy.

The relationship between household food insecurity and quality of life among children aged 7–13 years: effects of parent-reported disordered eating, anxiety and depression

BackgroundFood insecurity (FI) has been linked to adverse child health outcomes, including developmental, physical, and psychological disorders. However, little is known about the impact of FI on Lebanese children, especially considering the daily social and economic challenges the population faces. These challenges heighten children’s vulnerability, particularly with regard to disordered eating, anxiety, and depression, which may act as mediating factors affecting their overall quality of life. This study aims to assess the mediating effects of disordered eating, anxiety, and depression between FI and quality of life among Lebanese children aged 7–13 years.MethodsA cross-sectional study was conducted among 504 Lebanese parents of children aged 7–13 years. FI was assessed using the Arab Family Food Security Scale (AFFSS), quality of life using the KIDSCREEN-10, disordered eating with the Eating Disorder Examination-Questionnaire Short-Parent version, anxiety with the Spence Children’s Anxiety Scale-Parent, and depression with the Short Mood and Feelings Questionnaire-Parent version. Mediation analysis was performed using PROCESS MACRO v3.4 in SPSS, with 5000 bootstrapped samples.ResultsIn total, 30.8% of parents reported severe levels of household FI. The results of the mediation analysis showed that disordered eating, depression and anxiety fully mediated the association between FI and quality of life. Higher FI was significantly associated with higher disordered eating/depression/anxiety, whereas higher disordered eating/depression/anxiety were significantly associated with lower quality of life. FI was not directly associated with quality of life.ConclusionFI indirectly affects child’s quality of life through its impact on disordered eating, anxiety, and depression. Addressing these psychological disorders in children from food-insecure households appears to be essential to improve their overall quality of life. The implications are specific to Lebanon but may provide valuable insights applicable to similar socio-economically and politically challenged areas.

Using a Mobile Application Disease Self-management Program to Promote Blood Pressure Control and Quality of Life in Patients With Hypertension.

The study aims to assess the effectiveness of a mobile application disease self-management program regarding blood pressure control and quality of life for patients with hypertension. A single-blind randomized controlled trial. Participants in the control group (n = 51) received routine care, whereas those in the experimental group (n = 51) participated in a home-based intervention. They accessed the program on a mobile device, watching disease self-management content at least once every other day. Posttests were conducted upon return visit to the clinic after 3 months. The measuring outcomes included demographics, disease characteristics, and quality of life. After the intervention, significant results were observed in the experimental group regarding the control of systolic blood pressure and diastolic blood pressure. Furthermore, significant effects were observed in the overall improvement, as well as the physical and mental component summary of quality of life, compared with the control group. The primary outcomes can help control blood pressure and mitigate complications in patients with hypertension. Secondary outcomes include promoting overall quality of life and its physical and mental component summary while providing nursing staff with an alternative method of health education other than conventional methods.

Beyond the surface: understanding psychiatric disorders in individuals with spinal cord injury- a narrative exploration.

Spinal Cord Injury (SCI) presents a life-threatening condition that compromises the spinal cord's integrity. Among the complications affecting SCI patients are psychiatric disorders, whose causal mechanisms remain elusive. These disorders are often attributed to multifactorial aspects, encompassing physiological, neurobiological, psychological, and social factors. In the context of SCI patients, we are interested in identifying the specific factors that contribute to the development of psychiatric disorders in this population, emphasizing the critical need for prevention strategies and comprehensive therapeutic management, ultimately aiming to improve the affected patients' quality of life. The process of searching and selecting information was performed between August and December of 2023, utilizing PubMed, ResearchGate, and NCBI as the requisite databases for this review. To ensure precise information retrieval, keywords were strategically employed, focusing on publications spanning from 1985 to the present. MeSH terms, including spinal cord injury, acute spinal cord injury, psychiatric disorders, neuropsychiatry, cognitive impairment, and chronic pain, were applied. A total of 127 articles were identified through electronic searches, and 55 of these were chosen for inclusion in this review. The consulted studies encompassed various types, such as meta-analyses, systematic reviews, animal model experiments, and others. Various factors contributing to the onset of psychiatric disorders in patients with SCI were proposed, all grounded in evidence: neurobiological pathology; cognitive impairment; the impact of systemic diseases on psychological well-being; and, lastly, the correlation between chronic pain and diminished daily functionality, experiences widely encountered by SCI patients. The diagnosis of psychiatric disorders remains largely clinical and syndromic, with unclear causal mechanisms. Understanding psychiatric symptoms in SCI patients requires further investigation. Key contributing factors include neurobiological pathology linked to SCI, cognitive impairment, systemic and organ-specific diseases, and chronic pain associated with reduced functionality. We emphasize the importance of therapeutic and rehabilitative measures that address both physical and psychological health to improve overall quality of life.

Depression and quality of life in patients with Broca’s and subcortical stroke-related aphasia: A comparative study

Aim Aphasia, primarily recognized as a language disorder following stroke, often is presented with concurrent emotional and social difficulties, including depression. This study investigated whether the type of aphasia—Broca’s or subcortical—may be related to the prevalence of depression and overall quality of life (QOL) in affected individuals. Methods The present study involved 46 individuals with chronic aphasia resulting from left hemisphere strokes. Participants were divided into two groups: those with Broca’s aphasia and those with subcortical aphasia. Several assessment tools were utilized, including the Persian versions of Mini-Mental State Examination (MMSE), Western Aphasia Battery (P-WAB-1), the Beck Depression Inventory-II (BDI-II), and the Stroke and Aphasia Quality of Life Scale-39 (SAQOL-39). Results The results indicated that the average severity of aphasia was significantly lower in the Broca’s aphasia group (36.48 ± 8.05) compared to the subcortical aphasia group (62.83 ± 19.88). However, both groups demonstrated similar depression severity scores and their quality of life was largely comparable to each other. Conclusion This study underscores that living with aphasia, regardless of type, involves emotional and social challenges that may be extended beyond language difficulties, emphasizing the need to address these issues to improve the well-being of stroke survivors.

Effects of seamless care in the perioperative management of laparoscopic pancreatoduodenectomy on patients’ quality of life and postoperative complications

This study investigates the efficacy of the seamless care model in operative management for patients who have undergone laparoscopic Pancreatoduodenectomy, evaluating its potential effects on postoperative quality of life (QOL) and complications. This study encompassed patients who underwent LPD at our institution between February 2022 and May 2023. Patients were randomly allocated to either the standard care group(control group) or the seamless care group(intervention group) using a random number table method. QOL was assessed both preoperatively and postoperatively. The incidence of adverse events before to discharge was evaluated. No significant changes in preoperative QOL measures were seen between the two groups (P > 0.05). Postoperatively, the intervention group exhibited markedly superior physiological function scores and overall quality of life (P < 0.05), as well as a considerably reduced frequency of adverse events (P < 0.05). The intervention group exhibited significantly shorter times to first postoperative flatus and shortened hospital stays relative to the control group (P < 0.05), times to ambulation demonstrated no significant difference (P > 0.05). Seamless care significantly enhances quality of life and reduces adverse events following LPD, warranting its broader clinical implementation.

Treatment Efficacy of Theophylline in ADCY5-Related Dyskinesia: A Retrospective Case Series Study.

ADCY5-related dyskinesia is a rare disorder caused by mutations in the ADCY5 gene resulting in abnormal involuntary movements. Currently, there are no standardized guidelines to treat this condition. The aim of this study was to evaluate the efficacy of theophylline administration in improving symptoms and quality of life in patients with ADCY5-related dyskinesia. A retrospective study was conducted involving 12 patients (aged 2-41 years) with ADCY5-related dyskinesia. Participants completed a questionnaire about theophylline administration, including dosage, improvement of symptoms, adverse effects, and changes in quality of life. Data were analyzed for reported efficacy and side effects. Theophylline administration demonstrated substantial efficacy, with 92% (11 of 12) of patients reporting significant improvements in their movement disorders. The average improvement score was 7.0 ± 1.9 (mean ± SD) on a 10-point scale. Notable improvements included reductions in severity and frequency of episodes, improved gait, more independent mobility, psychosocial well-being, and quality of sleep. Adverse effects were reported by 6 patients, including dystonia, worsening of speech, headaches, nausea, impaired sleep, and agitation. Theophylline shows substantial promise as a treatment option for ADCY5-related dyskinesia, improving various aspects of patients' quality of life and movement disorder symptoms. Further research is needed to optimize dosing, to understand long-term effects, and to explore combinational drug therapies. Despite the small cohort size and the retrospective nature of this study, the results support theophylline administration to decrease dyskinetic movements and enhance overall quality of life in patients. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Prevalence and determinants of depression and its association with social support among cancer patients: implications for enhancing oncology care

BackgroundEarly detection of depression in cancer patients is essential for improving health outcomes. This study assessed the prevalence and determinants of depression among cancer patients and examined its association with social support.MethodA cross-sectional study was conducted at Al Amal Cancer Center, Al-Thawra Hospital, Hodeida City, Yemen (January–March 2023). Data on sociodemographic characteristics, depression (Patient Health Questionnaire, PHQ-9), and social support (Oslo Social Support Scale, OSSS-3) were collected. Multivariate binary logistic regression identified significant depression factors, and Pearson’s correlation was used to assess the relationship between social support and depression. A p value of < 0.05 indicated statistical significance.ResultsDepression incidence among cancer patients was 55% (n = 192). Multivariate analysis revealed that married (AOR = 9.472, p < 0.001) and divorced/widowed patients (AOR = 11.649, p < 0.001) were more likely to have depression than single individuals were. Higher education (diploma or above) was protective (AOR = 0.071, p < 0.001). Elevated lipid levels were linked to a lower depression risk (AOR = 0.189, p = 0.003), and a family history of cancer (AOR = 4.239, p < 0.001), longer disease duration (> 4 years) (AOR = 3.197, p = 0.006), and difficulty in activities (AOR = 8.704, p < 0.001) increased depression risk. A significant negative correlation between depression and social support was found (r = − 0.237, p < 0.001).ConclusionOver half of cancer patients experience depression, which is influenced by marital status, education, and disease-related factors. Social support significantly mitigates depression.Implications for practiceEnhancing social support and integrating mental health assessments by psychiatric professionals in oncology care is essential for improving the emotional well-being and overall quality of life of cancer patients.

Breast neurotization along with breast reconstruction after nipple sparing mastectomy enhances quality of life and reduces denervation symptoms in patient reported outcome: a prospective cohort study.

Persistent postoperative sensory loss significantly limits breast reconstruction following mastectomy. In addition, the absence of sensation profoundly impacts patients' physical well-being and overall quality of life. New surgical techniques involving nerve autograft intercostal nerve elongation have been introduced to neurotize reconstructed breasts. However, patient quality of life after neurotization has not been well evaluated. This study aimed to investigate improvements in patient quality of life in association with breast neurotization. A prospective cohort study of 132 patients treated at (blinded for review) between January 2018 and December 2022 was conducted. Two groups of patients who underwent nipple-sparing mastectomy (NSM) and breast reconstruction were compared: those with (n=67) and without (n=65) breast neurotization. Patient-reported outcomes were assessed via the BREAST-Q reconstruction module questionnaire and an additional questionnaire measuring sensation, nipple satisfaction, and breast symptoms. Objective measurements were conducted via the Semmes-Weinstein monofilaments test. With respect to patient-reported outcomes, the innervated group had significantly higher scores for nipple sensation and on the BREAST-Q domains of psychosocial well-being (71.6±18.1 vs. 62.8±18.6, P=0.006), sexual well-being (56.9±22.1 vs. 47.3±20.7, P=0.015), satisfaction with the medical team, as well as less frequent post-operative breast symptoms. In the subgroup analysis, the innervated group demonstrated higher scores in both autologous flap and implant-based reconstruction. Linear regression revealed a statistically significant relationship between objectively measured monofilament value and subjectively examined patient-reported outcomes: nipple sensation, breast sensation, and BREAST-Q score for the psychosocial well-being domain (coefficient:-4.922, P=0.033). Breast reconstruction with autologous nerve graft neurotization yields improved sensory outcomes and has a statistically significant positive impact on the quality of life of breast reconstruction patients.

A patient first perspective of sleep disturbance across therapeutic areas: a systematic literature review of qualitative studies.

Sleep, a vital pillar of health, impacts daily functioning and overall quality of life. Despite extensive research on sleep disturbances within specific therapeutic areas (TAs), there's limited understanding of how these disturbances affect patients across multiple TAs. This systematic literature review adopts a patient-centered approach to explore the meaningful aspects of health and concepts of interest relating to sleep and sleep disturbances across a variety of TAs, utilizing qualitative research to bridge the gap between patient experiences and clinical measures. A systematic search was conducted in Embase and PubMed for qualitative studies on sleep within selected TAs, using a pre-registered strategy. Initial screenings based on titles and abstracts were followed by full-text reviews and quality appraisal using the CASP checklist. From 4331 unique publications, 52 full-text articles were analyzed across 11 TAs. Thematic analysis highlighted issues within the sleep window, and proximal and distal impacts of sleep disturbances. Using thematic analysis a conceptual model was developed, illustrating a multitude of sleep disturbances from a patient-first perspective, which emphasized sleep quality's role in daily functionality. This review emphasizes the importance of incorporating patient perspectives into sleep research and clinical practice. By presenting a holistic conceptual model, it provides a foundation for developing outcome measures that reflect meaningful aspects of patients' sleep experiences. This patient-centered approach highlights the need for novel methodologies in sleep research, beyond traditional clinical outcome assessments, to capture the full spectrum of sleep disturbances' impacts on patients' lives across various TAs.

Prevalence of Depression and Associated Risk Factors among the Elderly population attending Government Medical College Hospital of North Karnataka- A cross-sectional study

Background: Depression is a significant concern among the elderly population, with adverse effects on physical, cognitive, functional and social wellbeing. Despite being a major public health issue, depression in elderly often goes unnoticed and untreated. Hence, this study was conducted to estimate the prevalence of depression and investigate the potential risk factors associated with depression among individuals aged above 60 years. Methods: This cross-sectional study was conducted at tertiary care hospital, BIMS, Belagavi. A total of 400 study participants were randomly selected and interviewed using a structured questionnaire which consisted of socio-demographic profile and The Geriatric Depression Scale (GDS) scale. GDS, a validated self-report assessment tool was used to assess depression. Statistical analysis, including chi-square test was used to determine association between depression and socio-demographic risk factors. Results: A total of 400 geriatric subjects participated in our study. Majority of them were females (54.5%) and from rural area (64.5%). The overall prevalence of depression was found to be 21.25%. Depression was more prevalent among females, rural residents, individuals staying alone or widowed. Illiteracy and presence of chronic disease were associated with higher rates of depression. Significant associations were found between depression and socio-demographic variables like gender, residence, marital status, literacy and presence of chronic illness. Conclusion: This study highlights high prevalence of depression among geriatric population with various socio-demographic factors playing a role in its occurrence. Early recognition and appropriate interventions for depression in the elderly are crucial to prevent adverse consequences and improve overall quality of life.