Orthodontic Study Models Research Articles

Comparison of various modes of acceleration of orthodontic tooth movement- A clinical study

The objective of the present study is to evaluate the effects of Micro-osteoperforations (MOPs), Corticision, Low Level Laser Therapy (LLLT) and Platelet Rich Plasma (PRP) on the rate of orthodontic tooth movement. Randomly10 patients were selected in each study group. All the studies had a split-mouth study design. All the patients were bonded with MBT 0.022 X 0.028 inch brackets and maxillary canine retraction was performed on 0.019 X 0.025 stainless steel wires with different methods of accelerating tooth movement. Data was collected from the orthodontic study models prepared from alginate impression taken at each appointment interval. The results of the study revealed that the amount of maxillary canine retraction was rapid in all the groups as compared to conventional method of orthodontic tooth movement and the results conclude thatmicro-osteoperfortaions showed better rate of accelerated orthodontic tooth movement as compared to other methods.

Cleft Laterality Dental Arch Relationship Outcomes for Children with Unilateral Cleft Lip and Palate in New Zealand.

To investigate cleft laterality dental arch relationship outcomes of children with non-syndromic complete unilateral cleft lip and palate (UCLP) in New Zealand. A retrospective nationwide study. Virtual 3D orthodontic study models collected prior to undertaking secondary alveolar bone grafting. A total of 104 patients with UCLP (L = 80: R = 24). Four calibrated assessors used the GOSLON Yardstick and 100 mm Visual Analogue Scale (VAS) to score the randomised models on 2 separate assessment sessions. Weighted Kappa were used to determine the intra/inter-rater reliability for the GOSLON and correlations for the VAS. Intra-rater reliability ranged from 0.57-0.88 (GOSLON) and 0.45-0.93 (VAS). Inter-rater reliability ranged from 0.62-0.86 (GOSLON) and 0.64-0.93 (VAS).GOSLON scores for the left UCLP were 31.2% for good/very good; 26.3% for fair; 42.5% for poor/very poor while the right UCLP scored 8.3% for good/very good; 37.5% for fair; 54.2% for poor/very poor. The mean VAS for left and right UCLP were 53.4 (sd 22.5) and 44.6 (sd 17.1) respectively. Neither the GOSLON nor VAS differences reached statistical significance (both P = .08). From a clinical perspective right UCLP had worse dental arch relationship outcomes, however, these differences failed to reach statistical significance. Further studies using larger sample sizes are required to determine if cleft laterality is an important consideration when investigating UCLP dental arch outcomes.

Prevalence of Hypodontia in North Indian Orthodontic Subjects and its Association with Other Dental Anomalies

Abstract Objectives: The objectives of the present study were to (a) estimate the prevalence of hypodontia in permanent dentition of the North Indian Orthodontic subjects and to compare the results of the present study with specific findings of other populations; (b) evaluate occurrence of hypodontia in relation to gender, tooth type, location and pattern of distribution in maxillary and mandibular dental arches. Materials and Methods: Initial Pretreatment Orthodontic records of 1063 patients in the age range of 12–30 years collected from the archives of the department and the subjects who reported to the routine outpatient department of the department for orthodontic treatment and gave their consent for collecting pre–treatment orthodontic records. The initial pretreatment records to diagnose hypodontia and other dental anomalies included (a) orthodontic study models, (b) orthopantomograms, and (c) relevant findings from patient history sheets. Results: Thirty-two subjects fulfilled the selection criteria thus, giving the prevalence rate of hypodontia in the North Indian Orthodontic population of 3.01% out of which 21 were females and 11 were males with most common age group of 12–15 years. Maximum number of subjects were found to have only 1 CMT more commonly in the anterior region than the posterior region of the jaw and more in mandibular arch with mandibular central incisor to be the most common type of congenitally missing permanent tooth. In majority of hypodontia subjects, the most common associated dental anomaly was retained primary tooth. Conclusion: The prevalence of hypodontia of this study was within the range of that reported in the literature. Prompt diagnosis of hypodontia and other anomalies at an early age can help in planning various treatment modalities with a multidisciplinary team approach to establish a functional and esthetic dentition.

Hologram Usage in Orthodontics as A Study Model: A Comprehensive Review

Abstract: Orthodontics, a specialized field of dentistry focused on correcting malocclusions and dental irregularities, has evolved significantly in recent years. Traditional study models, such as plaster casts and digital impressions, have been the cornerstone of treatment planning and evaluation. However, the advent of holographic technology has introduced a novel and promising approach for orthodontic study models. This comprehensive review explores the utilization of holograms in orthodontics, highlighting their potential advantages, applications, and challenges.

Geometric analysis of tooth size among different malocclusion groups in a Hispanic population

Tooth size ratio is important for optimal dentofacial esthetics, occlusal interdigitation, and postorthodontic treatment stability. Tooth geometry influences tooth size ratio; therefore, tooth size normative data may not be practical across diverse ethnic groups. This study aimed to determine whether there are significant differences in 3-dimensional tooth size among patients in the Hispanic population with Angle Class I, II, and III malocclusions. The data were collected using intraoral scanned orthodontic study models representing Hispanic orthodontic patients with Angle Class I, II, and III malocclusions. The scanned models were digitized and transferred to a geometric morphometric system. Tooth sizes were determined, quantified, and visualized using contemporary geometric morphometric computational tools. Tooth size was determined for all teeth and showed a significant difference in 4 out of 28 teeth: Maxillary right first molar, mandibular left second molar, mandibular right first molar and mandibular right second molar. This significant difference was noted among females and affected different malocclusion groups. Tooth size discrepancy in the Hispanic population varies among malocclusion groups, and the variation is determined by the participant's gender.

Analysis of the gender-identifying abilities of different odontometry methods - A Retrospective cross-sectional Study

Introduction: It is critical to identify the person in a criminal investigation process. Forensic odontology helps in the identification of the person using dentofacial structures as a differentiating tool in the criminal justice system. Several oro-dental anatomical landmarks like palate, lips and bite marks, teeth such as maxillary central incisors, canines and molars have been used in the identification of the gender of an individual based on the principle of individuality. Aims and objectives: Studying different odontometric methods such as palatal depth, mandibular canine index and maxillary inter-canine width for sex determination and compare it with the actual gender of an individual. Methodology: For this study, 72 pairs of orthodontic study models were analysed for gender determination based on three odontometric parameters viz. palatal depth, mandibular canine index and maxillary inter-canine width. The patient’s sex was not disclosed to the investigators until the completion of the model analysis. The measurements were taken using brass wire, divider, stainless steel scale and digital vernier calliper. The data was calculated and tabulated in a master chart and statistical analysis was done. Result: The results of odontometric measurement methods used for the gender determination study are in actual agreement with 32.6% male and 63.04% female population of Mumbai and the sub-urban region. Conclusion: The palatal depth, maxillary inter-canine width and mandibular canine index are simple, convenient, reproducible and reliable odontometric methods in the gender determination of individuals.

Orthodontic model analysis in the permanent dentition: A review of past, and current methods

The study models are regarded as the gold standard tool in orthodontics since they aid in the diagnosis, treatment planning and monitoring of the changes that may occur throughout treatment. Besides these, plaster models are also used to monitor growth and clinical audits. A study model accurately replicates the teeth, surrounding soft tissues and occlusion. Traditionally, the orthodontic study models have been used to measure the overjet and overbite, tooth size, arch length, arch width, the curve of Wilson and Spee, space analysis and diagnostic setup. However, plaster models are still preferred by orthodontists since impression-making is convenient, and most patients tolerate them well. With recent advancements in digital technology, intraoral scanners have eliminated the need for conventional impression procedures and plaster models. The digital orthodontic models have overcome the majority of disadvantages associated with plaster models. With the advent of automated analysis using digital models, the entire process of orthodontic treatment planning based on study models has become more convenient and user-friendly. This article aims to comprehend the various model analyses used for diagnosis and treatment planning in the permanent dentition stage and deliver insight into current digital methods.

Influence of Bolton’s analysis and Peck & Peck index on the pre and post-treatment overjet

Background: To evaluate the relationship between the overjet with pre and post orthodontic treatmentBolton’s analysis and with Peck & Peck index. Materials and Methods: Pre and post-treatment orthodontic study models (n=30) of patients in the age range of 18 to 35 years, who underwent orthodontic treatment were evaluated for overjet, Bolton’s analysis (overall ratio & anterior ratio) and Peck & Peck index (in 31,32,41&42). A digital Vernier caliper was used for all the measurements. The collected data was analyzed in SPSS software using appropriate statistical tests based on normality to compare the pre- and post-treatment mean values and Pearson’s correlation was done between the Bolton’s analysis and Peck & Peck index with overjet. The p value <0.05 was considered as statistically significant. Results: The Pearson’s correlation revealed an inverse correlation between Bolton’s anterior ratio and overjet (pre:-0.226, post:-0.254). The pre-treatment overjet with Peck & Peck index revealed an inverse correlation in PP 31 (-0.230) and positive correlation in other teeth. The correlation in the post-treatment overjet with Peck & Peck index was an inverse correlation in all teeth (-0.347; -0.184; -0.184 & -0.074 in PP31, PP32, PP41 & PP42 respectively).

Comparison between a human judge and automatic landmark identification on digital models

Accurate landmark identification is a prerequisite for accurate and reliable biomedical image analysis. Orthodontic study models are valuable tools for diagnosis, treatment planning, and maintaining complete records. The purpose of this study was to evaluate the reliability and validity of a software program (Align Technology, Inc) as a tool for automatic landmark location. Using digital intraoral scans of 10 dental arches, 4 calibrated human judges independently located cusp tips and interproximal contacts. The same landmarks were automatically identified by the software. Intraclass correlation coefficient (Cronbach α), absolute mean errors, and regression analysis were calculated. In addition, Bland-Altman 95% confidence limits were also applied to the data to graphically display agreement on landmark identification between the human judges and the software. The intraclass correlation coefficient between the software and the human judges' average for the x-, y-, and z-coordinates for all landmarks was excellent, at 1.0, 1.0, and 0.98, respectively. The regression analysis and Bland-Altman plots show no systematic errors for agreement on landmark identification between the human judges and the software. Landmark location was nearly identical between the software and the human judges, making the methods interchangeable.

Morphological Comparison of the Maxillary Arch in Buccal and Palatal Canine Impaction among Asian Population of Gujarati Origin: A Hospital-Based Study.

Aim: To estimate the differences in the maxillary arch morphology in buccal and palatal canine impaction in an Asian population of Gujarati origin. Methodology: An institutional ethics committee’s approval was acquired before the commencement of this study. Sixty subjects were enrolled in the study. Thirty subjects (20 females and 10 males) had a maxillary impacted canine either buccal or palatal and thirty control group participants were selected aged 13 to 18 years who sought orthodontic treatment at the tertiary health care center in Ahmedabad, Gujarat, in western India. Routine pre-treatment radiographs and dental plaster models with good anatomic details were recorded. Measurements of the inter-molar width, palatal depth, arch length, sum of the mesio-distal width of the upper incisors, and available arch space were recorded from prepared orthodontic study models using digital vernier calipers with an accuracy of 0.01 mm and brass wire. The ratio of palatal depth to inter-molar width (Ratio 1), arch length to inter-molar width (Ratio 2), and width of the maxillary incisors to available arch space (Ratio 3) were also secondarily calculated. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 21, IBM Inc. The normality of the data was assessed by the Shapiro–Wilk test. As the data was found to be normally distributed, bivariate analyses were also performed (one-way ANOVA test, Bonferroni post hoc correction). The level of statistical significance was set at a p-value less than 0.05. Results: The comparison of the inter-molar width, palatal depth, arch length, sum of the mesio-distal width of the upper incisors, available arch space, Ratio 1, Ratio 2, and Ratio 3 among controls and subjects with buccal and palatal canine impaction showed overall significant differences in the inter-molar width, palatal depth, arch length, sum of the mesio-distal width of the upper incisors, and available arch space when compared using one-way ANOVA as p < 0.05. Ratios 1, 2, and 3 also showed significant differences between the buccal and palatal canine impaction. Conclusion: An inadequate arch length (p < 0.0001) and a higher degree of crowding with reduced available arch space (p < 0.0001) may be considered as early risk factors for buccal maxillary canine impaction. An inadequate inter-molar width (p < 0.0001), and an increased palatal depth (p < 0.0001) with a clinically reduced mesiodistal width of the sum of maxillary incisors may be considered as risk factors for palatal maxillary canine impaction in an Asian population of Gujarati origin.

Post-treatment Stability in Orthodontic Retention with Twistflex Retainers—Do Patients Benefit from Additional Removable Retainers?

ObjectivesTo evaluate post-treatment movements of lower anterior teeth during orthodontic retention in patients with fixed twistflex retainers versus those with combined fixed and removable retainers.Materials and MethodsThis study was based on a retrospective data analysis of 57 adult patients during orthodontic retention. They were assigned to two groups: In group 1 (n = 30) the lower jaw was provided with twistflex retainers only and in group 2 (n = 27) with a twistflex combined with a removable retainer for night-time use. Orthodontic study models of the lower jaw were digitalized and superimposed. Tooth movements were analyzed at the retainer bonding (t0) and follow-up appointment ≥ six months later (t1). Rotational tooth movements (°) were measured around the x-axis (mesial/distal direction), the y-axis (buccal/lingual direction) and the z-axis (longitudinal direction, tooth axis). Translational tooth movements (mm) were registered along the x-axis (buccal/lingual direction), the y-axis (mesial/distal direction) and the z-axis (apical/coronal direction).ResultsCanine and incisor position changes during orthodontic retention were more pronounced in group 1 compared to group 2 except for canine rotations around the z-axis. In both groups in most of the cases stable lower incisor alignment could be found, but the proportion was significant higher in group 2 (group 1: 56.7% vs. group 2: 81.5%). Severe misalignment was present in 13.3% of the participants of group 1 and only in 7.4% of group 2. The extent of canine tipping and movements along the x- and y-axis in severe misalignment cases was significantly lower in group 2 compared to 1.ConclusionsLower incisor alignment was more stable in patients with combined fixed and removable retainers compared to fixed retainers only.Clinical RelevanceBased on the present findings, the routinely application of supplementary removable retainers can be recommended to enhance anterior tooth alignment in patients with fixed twistflex retainers.

Assessment of accuracy and reliabilty of measurements obtained on 3D scanned models to conventional models

Aims and Objectives: To conclude on superior method of model fabrication and compare accuracy and the reliability of measurements obtained on 3D scanned models to conventional models. Materials and Methods: A total of 20 orthodontic study models were obtained from the department of orthodontics and dentofacial orthopaedics with a full set of permanent teeth from the right first molar to the left first molar and no anomalies of the crown. The plaster models were measured to the nearest 0.01 mm using the Aerospace Electronic Digital Caliper. Identical plaster models were scanned by placing each arch on the integrated rotary table (dental wings 3SERIES) .The acquired data was then processed and exported in stereo lithographic format using DWOS CAD/CAM software. Digital casts were later measured to the nearest 0.123 mm using 3D-Tool 64-Bit Free Viewer V13. Results: indicated that all measurements for the arch and tooth size measurements for both methods were highly correlated (r . 0.99; P\0.05).Cronbach α value of the data at T1 and T2 from incisal segment ,canine segment and the molar segment measured using the two methods was very close to the ideal value of 1, indicating high intraobserver reliability.

An overview on the veracity of intraoral digital scanning system and utilization of iTero scanner for analyzing orthodontic study models both In-Vivo and Ex-Vivo.

In the domain of orthodontics, plaster models are contemplated as one of the important tools for diagnosis and treatment planning. In Dentistry, technological advancement has developed in the section of diagnostic devices, for example, the utilization of a 3D intraoral scanner, which can convert plaster models into digital models. With in-office utilization of this system, orthodontists can more meticulously and precisely construct custom braces, clear aligners, and orthodontic appliances. The digital data can be stored as a stereolithography file; it eliminates the disadvantages encountered with the storage of plaster models like breakage, space required, and distortion of the plaster models. ITero®element is the intraoral laser scanner (ILS) which utilizes parallel confocal scanning technology which maximizes the accuracy of the scan. By utilizing the iTero scanner, the dental measurement can be performed in OrthoCADTM software which is highly accurate. The objective of the contemporary study is to review the literature of studies on in-vivo and ex-vivo scanning with the iTero system.

Side effects of twistflex retainers-3D evaluation of tooth movement after retainer debonding.

Evaluation of tooth movement after retainer debonding in retainer-associated misalignment cases. This pilot study is based on aretrospective data analysis. Adult patients (age 25.5 ± 4.9years) wearing fixed twistflex retainers and having visible retainer-associated misalignment were included and examined for tooth movement after retainer debonding. Orthodontic study models were taken at retainer debonding (t0) and 14 (±1) weeks later (t1). They were digitally superimposed using 2D/3D dental imaging software and tooth movement was analyzed in all three dimensions. Atotal of 23teeth (12upper teeth: 10incisors, 2canines; 11lower teeth: 7incisors, 4canines) were analyzed. Mean overall tipping was 1.11 ± 0.82° in the mesial/distal direction (angulation, x‑axis), 2.02 ± 1.9° in the buccal/lingual direction (inclination, y‑axis) and 1.28 ± 0.99° around the tooth axis (z-axis). Mean overall bodily movement was 0.30 ± 0.31 mm in the mesial/distal direction (angulation, x‑axis), 0.10 ± 0.13 mm in the buccal/lingual direction (inclination, y‑axis), and mean in- or extrusion 0.22 ± 0.24 mm (z-axis). Mean tipping and bodily movement were more pronounced in the upper jaw. The present data shows that tooth movement after debonding of twistflex retainers can be expected in misalignment cases.

Comparison of three different instruments for orthodontic study model analysis

INTRODUCTION: A proper model analysis forms a vital part of the orthodontic diagnosis process, but it remains a time-consuming procedure. In day-to-day practice, many orthodontists assess the models subjectively, without applying analytical tests, due to the time it takes to do proper model analysis.1,2 Plaster dental models have long been the gold standard for orthodontic study model analysis and to calculate the Bolton index for tooth size disproportions, as well as intra-arch space discrepancies.3,4 Vernier callipers or needle pointed dividers are traditionally used to perform measurements on dental models.5 More recently digital orthodontic study models that are computer-based have been developed and have the potential to replace the traditional plaster orthodontic models.6 AIMS AND OBJECTIVES: The aim of this study was to do model analysis on one hundred orthodontic cases by making use of three different measuring tools. The objective was to see if a difference exists with regards to the measurements produced by the three different instruments and to compare the instruments with each other. MATERIAL AND METHODS: Three different instruments were used to measure Ave values on one hundred orthodontic study models. The three instruments included a Boley Gauge, Digital Vernier Calliper and Carestream 3600 scanner with accompanying software. The five values measured on the study models were: maxillary intercanine width, maxillary intermolar width, mesio-distal width of tooth 11, mesio-distal width of tooth 46 and mesio-distal width of tooth 41. RESULTS: The statistical analysis performed showed that the difference in measurements produced by the three instruments were not statistically significant for the inter-molar width (p = 0.849), intercanine width (p = 0.657), mesio-distal width of tooth 11 (p = 0.178) and mesio-distal width of tooth 41 (p = 0.240 The difference in measurements for the mesio-distal width of tooth 46 were statistically significant (p&lt;0.01). However no clinically significant difference was found when the measurements produced by the three instruments were compared. CONCLUSIONS: All three of the instruments produced accurate measurements and can be used confidently when doing a comprehensive study model analysis for orthodontic diagnosis and treatment planning. The values produced were similar for all three instruments with insignificant differences between the three.

Comparison of three-dimensional printing guides and double-layer guide plates in accurate bracket placement

BackgroundIn the current study, we aimed to evaluate the accuracy of indirect bonding by either three-dimensional (3D) printing guides or double-layer guide plates. The results may serve as a clinical reference for bracket placements.MethodsIn total, 140 teeth were collected and arranged into five pairs of full dentition. The marking points were labeled on the buccal/labial surface of the crown in these orthodontic study models. (1) 3D printing guide: A digital profile was generated using an intraoral scanner. Two types of indirect bonding guide, namely the whole denture type and the single tooth type, were designed with the 3Shape TRIOS® Standard intraoral scanner and fabricated using 3D printing technology. (2) Double-layer guide plate: A working model was obtained by replicating the experimental models, and the double-layer guide plate was then made of the inner layer soft film (1.0 mm thickness) and the outer layer hard film (0.6 mm or 0.8 mm thickness). Brackets were transferred from working models to study models by the indirect bonding trays. We measured and analyzed the distance between marking points and bracket placement. Statistical analysis was done using SPSS 20.0 software. The accuracy of indirect bonding between 3D printing guide and double-layer guide plate was compared using paired t-test.ResultsAccording to our data, there was a significant difference between the 0.6 mm group and 0.8 mm group when the brackets were indirectly adhered using double-layer guide plates (p = 0.036). However, no statistical significance in bracket positioning accuracy was revealed between two types of 3D printing guide (p = 0.078), as well as between the 3D printing guide group and the 0.6 mm double-layer guide plate group (p = 0.069).ConclusionsWhen applying double-layer guide plates for indirect bonding, the 0.6 mm group is more accurate than the 0.8 mm group. When utilizing 3D printing guides for indirect bonding, whole denture type is more accessible than single tooth type but with no significant difference in accuracy. The accuracy of indirect bonding is comparable when using 3D printing guides (whole denture type) and double-layer guide plates (0.6 mm).

Reliability of a Categorical Scale (GOSLON) and a Continuous Scale (10-cm Visual Analog Scale) for Assessing Dental Arch Relationships Using Conventional Plaster and 3D Digital Orthodontic Study Models of Children With Complete Unilateral Cleft Lip and Palate.

To assess reliability of scoring plaster models and their 3D digital copy of children with complete unilateral cleft lip and palate (CUCLP) using a continuous scale (10-cm visual analog scale [VAS]) and a categorical scale (GOSLON Yardstick). Reliability observational study involving 3 trained GOSLON Yardstick assessors blinded to the origin of the models. Models from 35 New Zealand (NZ) and 35 Oslo CUCLP patients were standardized and randomly ordered before rating. Assessments were undertaken using the GOSLON and the VAS for both model formats. Twenty percent of sample were randomly selected and rescored at the first assessment, and whole sample was rescored 1 week later. Weighted κ was used to assess GOSLON reliability, while correlation was used for the VAS. The VAS and GOSLON intra- and inter-rater agreement was similar for both model formats. Repeat measurements on the day have similar intra-rater reliability as repeat measurements at least a week part. There was no significant difference between the 2 model formats, and both the GOSLON and VAS found the NZ models were significantly worse than Oslo. A 10-cm VAS is a reliable method to assess dental arch relationships and appears to have good face validity when compared to GOSLON. The VAS allows for statistically robust rankings of the dental arch relationships, although more studies will be required to enable the VAS scores to have greater clinical meaning. The 3D digital models can be used for GOSLON and VAS rankings with a high degree of reliability.

Conventional Vs Digital Impressions: Acceptability, Treatment Comfort and Stress Among Young Orthodontic Patients.

Objective:The objective of the present study was to compare patients’ acceptability, comfort and stress with conventional and digital impressions.Materials and Methods:Thirty young orthodontic patients (15 males and 15 females) who had no previous experience of impressions were enrolled in this study. Conventional impressions for orthodontic study models of the dental arches were taken using an alginate impression material (Hydrogum®, Zhermack Spa, Badia Polesine, Rovigo, Italy). Fifteen days later, digital impressions of both arches were acquired using an intraoral scanner (CS3600®, Carestream Dental, Rochester, NY, USA). Immediately after impression taking, patients’ acceptability, comfort and stress were measured using two questionnaires and the State anxiety scale.Results:Data showed no difference in terms of anxiety and stress; however, patients preferred the use of digital impressions systems instead of conventional impression techniques. Alginate impressions resulted as fast as digital impressions.Conclusions:Digital impressions resulted the most accepted and comfortable impression technique in young orthodontic patients, when compared to conventional techniques.

Saliva Leptin Levels in Tooth Movement during Initial Stage of Orthodontic Alignment: A Pilot Study

Introduction: During orthodontic tooth movement, the early response of periodontal tissues to mechanical stress is an acute inflammatory reaction. Mechanical stress from orthodontic appliances is believed to induce cells in the periodontal ligament (PDL) to form biologically active substances, such as enzymes and cytokines, responsible for connective tissue remodeling (Nishijima Y et al 2006). Leptin, a polypeptide hormone has been classified as a cytokine (Zhang et al 1994). Earlier findings concluded that leptin at high local concentrations protects the host from inflammation and infection as well as maintaining bone levels. It has been also suggested that leptin plays a significant role in bone formation by its direct effect on osteoblasts (Alparslan et al 2010). This pilot study aimed to study leptin in saliva and its association with tooth movement during initial orthodontic alignment. Objectives: To determine if there are any differences in saliva leptin level before and after orthodontic alignment. Material and methods: Ten orthodontic patients (7 girls and 3 boys; mean age, 16.76 ± 1.1 years) with crowding (up to 5mm) that required orthodontic fixed appliances, on a non-extraction basis as part of the treatment plan, were recruited in this longitudinal study. Orthodontic study models were constructed at baseline and at 6- weeks after orthodontic treatment commenced. Full fixed orthodontic appliances with initial 0.014” Nickel Titanium archwire placed. The amount of crowding was measured, before and after initial alignment with an electronic digital caliper (Max-Cal, Japan Micrometer Ltd, Tokyo, Japan) with an accuracy of up to 0.01mm. Unstimulated morning saliva sample were collected at all visits, after at least an 8-hour period of fasting and no-toothbrushing. After centrifugation (4000x g;10min), the samples were stored at -25C and tested using Leptin Abnova LEP Human ELISA kit (KA3080) which was subsequently analyzed. Subjects’ periodontal health status was also monitored throughout the study. Ethical approval (ID IREC 262) was received on 7th April 2014 from International Islamic University Malaysia Research Ethics Committee (IREC). Results: Leptin concentration in saliva was significantly decreased in a time-dependant manner (t(9)=8.60, p&lt;0.001), from before orthodontic treatment (7016.45± 425.15 pg/mL) and 6 weeks after bond-up (4901.92± 238.64 pg/mL). Conclusion: Leptin concentration in saliva is decreased during orthodontic tooth movement in initial alignment stage.

Demographics Characteristics and Analysis of Malocclusions of Orthodontic Patients Seen at IIUM Dental Specialist Clinic, Kuantan, Pahang

Introduction: Malocclusion is one of the most common dental problems observed. Limited data is currently available regarding the demographics of malocclusion observed locally. Materials And Methods: This is a retrospective study where 770 patients were recruited from May 2009 till December 2014. 560 orthodontic study models that met the inclusion criteria were examined and the malocclusions were classified according to the British Standard Institute (BSI) incisor classification. Demographic pattern and their relationship were analysed by structural equation modelling using SPSS (version 23.0). Results: From 560 study models analysed, 72% were female. The age of the patients ranges from 7-12 years old (17.1%), 13-17 years old (55.9%) and &gt;18 years old (27.0%). Majority of the patients were Malay followed by Chinese (5.7%), Indian (1.8%) and other races (1.8%) Treatments received were fixed appliances (FA) (60.0%), removable appliances (RA) (12.5%), functional appliances (FnA) (1.1%), combination of RA and FA (16.1%), combination of FnA and FA (2.1%) and consultation (8.2%). Types of malocclusions observed were Class I (25.7%), Class II/1(32.7%), Class II/2 (7.5%) and Class III (34.1%). There was significant association (p&lt;0.05) between age and gender towards the types of malocclusions and treatments received were observed. Conclusion: Age and gender play significant role in determining the types of treatment received by patients with malocclusion. Data obtained will be beneficial for departmental future management and clinical planning.