Goji berries are a well-known medicinal and edible plant that has been consumed as both a health food and a traditional herbal medicine since ancient times. Rapid and accurate identification of their geographical origin is crucial for quality control and consumer protection. In this study, a fast and effective traceability method for Goji berry origin is proposed, based on a voltammetric electronic tongue(E-tongue) combined with a hybrid MVMD–MGRU/I-TCN (Multivariate Variational Mode Decomposition–Multi-layer Gated Recurrent Unit/Improved Temporal Convolutional Network) Hybrid model. Taste information from Goji berries collected across nine different production regions was obtained using the E-tongue, and a time-series modeling framework was established through the proposed hybrid architecture. The MVMD–MGRU branch captures dynamic temporal dependencies and time-domain feature representations, while the I-TCN branch enhances global temporal perception and local feature extraction through a pyramid convolution mechanism that expands the receptive field of dilated convolutions. The features extracted by both branches are adaptively fused to leverage their complementary strengths, and the fused representation is fed into a decision network for recognition and classification. Experimental results demonstrate that the proposed multi-branch feature fusion strategy outperforms single-modal feature extraction methods, achieving test accuracy, precision, recall, and F1-score of 99.26%, 99.31%, 99.26%, and 0.9926, respectively. This study provides a novel and efficient approach for the rapid identification of Goji berry origin and offers valuable insights into the traceability of other traditional Chinese medicinal materials.

This article theoretically summarizes the integrity of style and task in Uzbek literary criticism using the example of scientific thinking by Matyakub Kushzhanov , in addition, using the example of the work “Soul and Appearance”, the academician’s theoretical views on the renewal of poetic thinking and aesthetic principles in Uzbek literary criticism of the 70s of the twentieth century are shown. Also, from a scientific and theoretical point of view, the critic’s opinions regarding the skill of using literary information and scientific facts, the creative spirit and critical views are analyzed. In world literature, serious attention is paid to the mediating role of critical thinking, the relationship between hypothesis and fact, the nature of the process of interdisciplinary integration, the designation of the paradigm of literary criticism, the consideration of literary traditions and innovative skills, the choice of the author's concept and the position of the researcher. World literary criticism has accumulated a wealth of experience in defining the creative credo of a critic, describing the criteria of a scientific approach and aesthetic evaluation, determining individual style and skill, and assessing the goals and objectives of theoretical interpretation. Studying the principles of poetic research into a logically connected life and the criteria for aesthetic evaluation of an essence as a complex complex, generalizing the spirit of creativity and the process of philosophical observation of logical syllogism, assessing the individual interpretation of the analysis of a scientific problem will bring clarity to the issues under consideration. The existing scientific and theoretical experience requires a serious study of the problems of analyzing literary criticism, the study of the creative originality of a hypothesis, fact and literary information helps to visualize the connection between language and speech as a whole. When preparing the article, hermeneutic, structural, historical-comparative, functional methods, as well as microanalysis were used alternately. In the process of studying the problem, the skills and style of presentation as a whole were tested.

ABSTRACT In this article, we make three contributions to our understanding of place-based Confederate commemoration. First, we demonstrate that neighborhoods are a widespread yet understudied site of Confederate commemoration through an inventory of 297 southern United States neighborhoods commemorating the Confederacy (NCCs) with neighborhood or street names. Second, informed by critical toponomy, we use 2020 U.S. Census data to test two hypotheses regarding the relationship between Confederate commemoration and neighborhood racial composition: (a) NCCs house larger proportions of white residents than do other neighborhoods; and (b) NCC populations are more likely to surpass the 85% white threshold with which we define white spaces. Sociologists apply the term white space to social settings such as overwhelmingly white neighborhoods in which whiteness is normalized, and Black people are marginalized. Findings vary by geographical context. Outside metropolitan areas, Census data support both hypotheses. Within metropolises’ urban cores, however, the hypotheses’ directionality is reversed: Black residents comprise larger percentages of NCCs than of other neighborhoods. Third, to gain perspective on these divergent findings, we present selected case studies of neighborhood origins and their demographic trajectories. These vignettes suggest ways that Confederate commemoration intersects with race and racial politics in the ongoing negotiation of community identity.

This article is devoted to the study of the problem-thematic originality of modern Crimean poetry, as represented in lyrical anthologies and on Internet sites. The aim of the research is to identify the artistic features of the poetry of contemporary Crimean authors. The scientific novelty is determined by the fact that, for the first time, the main trends in the development of Crimean poetry at the beginning of the 21st century are considered monographically. The study found that modern Crimean poetry, formed under the influence of complex historical and political contexts, reflects many themes and motifs related to identity, memory, nature, and socio-political changes. The dominant theme of Crimean poetry remains landscape lyrics, developing under the influence of the Russian romantic tradition. By focusing on the beauty of the southern peninsula, modern authors enrich landscape lyrics, firstly, by strengthening civic-patriotic motives and images, conveying historical connections between the past and the present, and affirming the importance of the Crimean land as an integral part of Russia (lyrics by T. Shorokhova). Secondly, through a philosophical component related to the motifs of separation, loss of spiritual connection with native places, where Crimea is perceived as an image of a spiritual Home; questions of existence, loneliness and the search for the meaning of life are often resolved through metaphors of natural phenomena (works by E. Baranova, K. Vikhlyaev). Thirdly, the synthesis of temporal layers – ancient, medieval, Soviet – actualizes the dialogue of eras and personal authorial experiences, also enhancing the philosophical component of landscape lyrics (poetry by Yu. Kotler, E. Korobkina, L. Boldov). Fourthly, the "resort myth" receives a new accentuating sound, where the exotic beauty of Crimean nature is ironically comprehended through the cliché consciousness of the modern tourist (M. Matveeva).

This article is dedicated to the study of the artistic originality of the translation of Ivan Bunin's story "Stars" (1930), which was based on a fragment of the memoirs of the French writer Frédéric Mistral. The aim of the study is the identification of the artistic and semantic features of Bunin's translation. For us, it is important to establish its connections with Russian folklore, the writer's philosophical lyrics, and the nostalgic sentiments of the émigré period. The scientific novelty of the research consists in the fact that we are identifying, for the first time, Bunin's creative approach to translation, which transforms into an independent artistic statement. As a result of the research, the following was established. First, the image of the star, associated with motifs of nostalgia, philosophical reflections on fate, and connection with Russian folklore, turns out to be symbolically multifaceted in the context of Bunin's poetics. Second, Bunin applied a conscious selection of material (Chapter 11) and creative transformation, condensing the meaning of the title, enhancing folklore through the image of the shepherd Jean, and adding autobiographical motifs. Third, Bunin's translations of the 1930s are not utilitarian work, but an artistic act of cultural dialogue, poetic reflection, and spiritual overcoming, changing traditional representations.

Los antiinflamatorios no esteroides (AINEs) son uno de los grupos farmacológicos más conocidos y utilizados en la medicina moderna. En el contexto del ejercicio físico son usados por su acción antiinflamatoria y analgésica. El objetivo del presente estudio fue determinar la efectividad de los antiinflamatorios no esteroides en el tratamiento del dolor muscular tardío (DMT), para lo cual se llevó a cabo una revisión durante los meses de octubre a diciembre de 2013 en las bases de datos electrónicas Pubmed, Scopus y SportDiscus, mediante una estrategia de búsqueda de artículos que incluyeran las siguientes palabras clave: antiinflammatory non steroid drugs, NSAIDs, delayed onset muscle soreness y DOMS. Se identificaron 31 estudios, de los cuales 30 eran investigaciones originales y un meta-análisis. Se recuperaron 26 artículos a texto completo y cinco únicamente el resumen. Después de analizar los trabajos se concluye, que si bien los AINEs muestran cierta efectividad real para aliviar el DMT, existe gran diversidad en la dosis, el tiempo de administración utilizado y las características generales de los sujetos en los estudios, por lo que se requieren más investigaciones para establecer su efectividad real.

The Ba-promoted Gd2O3 system is highly efficient for the oxidative coupling of methane (OCM) to C2H6 and C2H4 with N2O as the oxidant (N2O–OCM), but not with O2 (O2–OCM), outperforming previously developed catalysts. However, the lack of a molecular-level understanding of the enhanced N2O effect hinders not only further improvements of this system but also the rational design of other possible catalysts. By utilizing steady-state isotopic transient kinetic analysis (SSITKA) and temporal analysis of products techniques, we show that the kind of adsorbed oxygen species formed from the oxidants, O2 and N2O, is a key descriptor controlling the selectivity to C2-hydrocarbons (C2H4 and C2H6). Monatomic oxygen species should be primarily involved in the formation of C2H6, while biatomic oxygen species participate in CH4 oxidation to carbon oxides. Their surface concentration in N2O–OCM can be controlled by Ba loading. The loading hinders the rate of conversion of monatomic oxygen species to biatomic oxygen species. The coverage by these species determines the concentration and the lifetime of surface intermediates leading to gas-phase CO and CO2. The SSITKA results obtained with the Ba-promoted catalysts used in N2O–OCM suggest that C2H6 can be formed on the catalyst surface in addition to the main pathway occurring in the gas phase. The fundamentals elucidated in this study, which are relevant for controlling the selectivity to C2-hydrocarbons, may be of general character and can be used to develop other catalysts that operate selectively in OCM, not only with N2O but also with O2. These results also highlight the potential of transient/steady-state (micro)kinetic analysis to clarify the kind of adsorbed oxygen species and their interaction with the catalyst surface as well as their role in product formation in various selective oxidation heterogeneous reactions.

Hinduism is one of the oldest religions in the world, and is characterized by its wide diversity of beliefs, rituals, rites and worship. Worship is a fundamental pillar of this religion, as it reflects the Hindu perception of the universe, man, and the deity worshiped and sacred in their belief. The research problem is represented by the diversity of worship in Hinduism, a great diversity between sects and social classes, which makes it difficult to determine unified worship practices. Hindu worship has evolved over the ages, and has been influenced by many cultural, social and political factors, which makes understanding it require an in-depth historical study. Hindu worship is closely linked to Hindu philosophy and spiritual beliefs, which makes studying it require a deep understanding of these aspects. We have reached results that represent a deeper understanding of the Hindu religion, as worship is an essential part of this ancient religion, shedding light on the cultural and religious diversity in India, as the Hindu religion is The most widespread religion in India, deepening the dialogue between religions and cultures through a better understanding of Hindu worship, recommendations, the need for cooperation between researchers from different disciplines; to study a complex phenomenon such as Hindu worship and the development of its rituals over time, the importance of conducting field studies; to directly observe devotional practices and understand their cultural and social context.

The construct of pathological demand avoidance (PDA) is relatively new and contested. Clinical reports indicate a population who obsessively resist everyday demands and have an extreme need for control. Children and adolescents who might experience PDA, and their families, struggle significantly in their daily lives, creating a need for more research into the phenomenon. To assist the developing research field, this scoping review focuses on the methodologies used to study PDA in children and adolescents. A systematic search of six databases and grey literature uncovered 57 unique records after duplicates were removed. 21 documents containing 22 studies were retained for analysis. Of the 22 studies, 21 were from the UK and one was from the Faroe Islands. There were 18 quantitative analyses and 11 qualitative analyses. Half of the studies were cross-sectional and quantitative and almost half used mixed methods. Samples were non-representative and studies often used comparison groups of children with and without PDA. Researcher’s conceptualizations of PDA were coded into categories of emotional, socio-cognitive, and neurological differences. Studies of PDA focused mostly on PDA symptoms, mechanisms, and precipitants, with fewer studies of PDA origins and problems resulting from PDA or possible supports for individuals. The EDA-Q and the DISCO were the main measures used to identify PDA. Quantitative data were often analyzed using inferential statistics, and qualitative data were analyzed using thematic analysis, content analysis, and narrative summaries. Implications for future research are discussed.

This paper focuses on the role of diffusion-weighted MRI of ovarian tumors as a potential biomarker to detect and characterize malignancy, and to improve the accuracy of preoperative diagnosis and postoperative follow-up to optimize therapeutic management. This is an original retrospective study of 76 patients with ovarian masses who underwent surgery between May 2014 and March 2016 at the "Dr Carol Davila" Central Military University Gynaecology Department. Patients underwent preoperative, 6-month, and 12-month postoperative evaluation of ovarian tumors using diffusion-weighted MRI. Due to the accuracy of this method using specific sequences in tissue characterization, magnetic resonance imaging can be used in the diagnostic work-up of complex adnexal masses.

ObjectivesThe emergence of artificial intelligence (AI) is catching the interest of hospital pharmacists. A massive collection of health data is now available to train AI models and hold the promise...

Studies of the fundamental origins of friction have undergone rapid acceleration in recent years by providing valuable information on the nanoscale mechanisms responsible for friction at the macroscopic level. Significant efforts have been directed at developing composite nanofluids and nanoparticle additives to unlock new tribological properties unattainable by traditional lubricants. The studies are now further evolving by developing methods to achieve active control over nano- and/or mesoscale friction through the application of magnetic and electric fields external to the contact. These methods constitute an area of rapidly growing interest, and they also illuminate how the performance of conventional lubricants could be enhanced through the synergistic addition of nanoparticles (NPs). This mini review highlights 25 publications that collectively reveal significant progress, as well as important outstanding challenges, to the fundamental understanding of how the addition of NPs impacts lubricant performance. The first two topics focus on how Quartz Crystal Microbalance (QCM) nanotribological response to solid contacts can be linked to macroscale friction coefficients in the boundary lubrication regime and how QCM response upon immersion into a liquid is linked to macroscale lubricity in the mixed and hydrodynamic regimes. The third and fourth topics highlight the pivotal role of nanoparticle charge and surface treatments, while also indicating that the rolling of nanoparticles is ineffective and/or detrimental. The fifth topic focuses on applications that demonstrate the tuning of friction by varying nanoparticle electric charge and/or an external electric potential. The highlighted literature was selected to demonstrate a range of experimental and theoretical research, to provide direct connections between the nanoscale and macroscale tribological attributes, and to emphasize environmentally friendly lubricating materials such as water-based nanofluids.

Background:Maternal cigarette smoking during pregnancy (MSDP) is associated with numerous adverse health outcomes in infants and children with potential lifelong consequences. Negative effects of MSDP on placental DNA methylation (DNAm), placental structure, and function are well established.Objective:Our aim was to develop biomarkers of MSDP using DNAm measured in placentas (), collected as part of the Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function double-blind, placebo-controlled randomized clinical trial conducted between 2012 and 2016. We also aimed to develop a digital polymerase chain reaction (PCR) assay for the top ranking cytosine–guanine dinucleotide (CpG) so that large numbers of samples can be screened for exposure at low cost.Methods:We compared the ability of four machine learning methods [logistic least absolute shrinkage and selection operator (LASSO) regression, logistic elastic net regression, random forest, and gradient boosting machine] to classify MSDP based on placental DNAm signatures. We developed separate models using the complete EPIC array dataset and on the subset of probes also found on the 450K array so that models exist for both platforms. For comparison, we developed a model using CpGs previously associated with MSDP in placenta. For each final model, we used model coefficients and normalized beta values to calculate placental smoking index (PSI) scores for each sample. Final models were validated in two external datasets: the Extremely Low Gestational Age Newborn observational study, ; and the Rhode Island Children’s Health Study, .Results:Logistic LASSO regression demonstrated the highest performance in cross-validation testing with the lowest number of input CpGs. Accuracy was greatest in external datasets when using models developed for the same platform. PSI scores in smokers only () were moderately correlated with maternal plasma cotinine levels. One CpG (cg27402634), with the largest coefficient in two models, was measured accurately by digital PCR compared with measurement by EPIC array ().Discussion:To our knowledge, we have developed the first placental DNAm-based biomarkers of MSDP with broad utility to studies of prenatal disease origins. https://doi.org/10.1289/EHP13838

Earthworm extracts have become an interesting research area in cancer research due to their ingredients with anticancer and antiproliferative activities. Determining the anticancer effect of an extract on cancer cells may lead to new treatment strategies and alternative medicine to at least reduce the toxic effects of chemotherapeutic agents. In the present study, we aimed to raise awareness for drug development and future anticancer therapeutics by emphasizing the nature of earthworm extracts and the types of cancer they are used in through a systematic review. A systematic search of CINAHL, PubMed, Medline, Scopus and Web of Science databases was conducted to identify publications published between January 2018 and December 2022. We used different arrangements of the keywords ‘earthworm’, ‘earthworm extract’ and ‘anticancer effect’. We identified original studies written in English depicting in vitro and in vivo cytotoxic effects of earthworm extracts on cancer cells, and included these studies in our review. We found 15 studies matching our search criteria. Among the studies, Eisenia foetida (Savigny) was determined as the most studied earthworm, and colon cancer was the most frequently studied cancer type. The coleomic fluid was found to be the commonly used extract yielding positive results.

Altai heroic tales are unique monuments of the people’s epic heritage. They act as a cultural code that preserved the originality of the ethnic worldview, traditions of the people, as well as the peculiarities of their poetic language. At the same time, the Altai epic has much in common and peculiar in comparison with the epics of other Turkic-speaking peoples. The study of the epic style originality is special interest for folkloristics. The relevance of this study is determined by the insufficient study of style features of the Altai people’s heroic tales. The scholarly novelty of the work consists in the fact that it is the first to study the types of repetition as one of the stylistic phenomena of the Altai epic. The purpose of this research is to study repetition as a stylistic phenomenon of folk poetics. The sources for the study were the heroic tales published in the series “Altai Bogatyrs”. An important criterion for selecting sources for the study was the observation of this phenomenon in authentic texts, where the features of the narrator’s living language are preserved to a greater extent. The study is based on the analysis of Altai heroic tales from different narrators and other folklore sources. The descriptive method, methods of comparison and generalization were also used in the work. As a result of the study, the types of repetitions found in the Altai epic were identified and described; their main functions were defined. It is established that repetition in folklore text is an important and multidimensional phenomenon. In heroic tales it is manifested at different levels. Repetitions of individual words and word combinations, phrases and whole episodes are distinguished. According to the frequency of use, there are twofold, threefold and more repetitions. Repetitions occur within a line, at the beginning, end or at the junction of poetic lines, forming such stylistic figures as anaphora, epiphora and epanaphora. Each type of repetition fulfills a certain function in the text. The study has shown that the functioning of repetitions in heroic tales differs in the activity of their use by narrators.

Comparison of efficacy of acupuncture-related therapies in treating Acute Gouty Arthritis: A Network Meta-Analysis of Randomized Controlled Trials

BackgroundThe HOME-CoV (Hospitalisation or Outpatient ManagEment of patients with SARS-CoV-2 infection) score is a validated list of uniquely clinical criteria indicating which patients with probable or proven COVID-19 can be...

Pregnancy Care Utilization, Experiences, and Outcomes Among Undocumented Immigrants in the United States: A Scoping Review

This article aims to assess the reproducibility of Manufacturer and User Facility Device Experience (MAUDE) data-driven studies by analyzing the data queries used in their research processes. Studies using MAUDE data were sourced from PubMed by searching for "MAUDE" or "Manufacturer and User Facility Device Experience" in titles or abstracts. We manually chose articles with executable queries. The reproducibility of each query was assessed by replicating it in the MAUDE Application Programming Interface. The reproducibility of a query is determined by a reproducibility coefficient that ranges from 0.95 to 1.05. This coefficient is calculated by comparing the number of medical device reports (MDRs) returned by the reproduced queries to the number of reported MDRs in the original studies. We also computed the reproducibility ratio, which is the fraction of reproducible queries in subgroups divided by the query complexity, the device category, and the presence of a data processing flow. As of August 8, 2022, we identified 523 articles from which 336 contained queries, and 60 of these were executable. Among these, 14 queries were reproducible. Queries using a single field like product code, product class, or brand name showed higher reproducibility (50%, 33.3%, 31.3%) compared with other fields (8.3%, P = 0.037). Single-category device queries exhibited a higher reproducibility ratio than multicategory ones, but without statistical significance (27.1% versus 8.3%, P = 0.321). Studies including a data processing flow had a higher reproducibility ratio than those without, although this difference was not statistically significant (42.9% versus 17.4%, P = 0.107). Our findings indicate that the reproducibility of queries in MAUDE data-driven studies is limited. Enhancing this requires the development of more effective MAUDE data query strategies and improved application programming interfaces.

The genome organization of the Lake Magadi tilapia, Oreochromis Alcolapia grahami, a cichlid extremophile