AimThe aim of this study is to examine the relationship between the coping attitudes and compulsive online buying behaviors of nurses. MethodsThis descriptive and correlational study was conducted with 253 nurses working in a research and training hospital in Istanbul between June and December 2022. Data were collected using a ‘Participant Information Form’, the ‘Coping Attitudes Assessment Scale (R-COPE)’, and the ‘Compulsive Online Shopping Scale (COSS)’. Data were analyzed using descriptive statistics, Pearson's correlation coefficient, and multiple linear regression analysis. A p-value of <0.05 was considered statistically significant. ResultsThe mean R-COPE score of the participants was 87.79 ± 10.40, and their mean COSS score was 26.00 ± 25.03. There was a negative and statistically significant correlation between the total R-COPE scores and the total COSS scores of the participants (p < 0.01). The coping attitudes (β = −0.147) were a significant and negative predictor of compulsive online buying behaviors. Marital status (β = 0.152), frequency of access to the internet (β = 0.273), frequency of online shopping (β = 0.365), and monthly amount of money spent for online shopping (β = 0.123) were significant and positive predictors of compulsive online buying behaviors. These variables collectively explained 31 % (ΔR2 = 0.311, p = 0.000) of the total variance in the compulsive online buying behaviors of the participants. ConclusionNurses had moderate levels of coping attitudes and low levels of compulsive online buying behaviors. Having low levels of coping attitudes, being single, accessing the internet frequently, doing online shopping frequently and spending a high amount of money for online shopping every month predicted the compulsive online buying behaviors.