Petrological, geochemical, and isotope geochronological aspects of the evolution of calc-alkaline magmatism were investigated in the Western Okhotsk flank zone, the Okhotsk segment, and the Eastern Chukchi flank zone of the Okhotsk-Chukotka volcanic belt (OCVB). The OCVB is a tectonotype of continental margin volcanic belts comprising much greater volumes of felsic ignimbritic volcanics compared with mature island arcs (MIA, Kuril-Kamchatka and Aleutian) and the Andean continental margin. The volcanic rocks of continental margin volcanic belts (OCVB and Andean belt) are enriched in K, Ti, and P compared with the rocks of MIA and show a trend toward the field of high-potassium calc-alkaline series. Primitive andesite varieties (Mg# > 0.6) were not yet found in the OCVB, but there are relatively calcic varieties unknown in Andean-type structures and a significant fraction of moderately alkaline rocks, which are not typical of MIA. Variations in trace and major element characteristics in the basalts and andesites of the OCVB were interpreted as reflecting the competing processes of assimilation/mixing and fractional crystallization during the evolution of the parental basaltic magma. Significant lateral variations were established in the composition of the mantle sources of calc-alkaline magmas along the OCVB over more than 2500 km. The initial isotopic ratios of Sr, Nd, and Pb in the volcanics of the Okhotsk segment are relatively depleted and fall near the mixing line between PREMA and BSE. The magma source of the Western Okhotsk flank zone is most enriched and approaches EMI, whereas that of the central and eastern Chukchi zones contains an admixture of the EMII component. The geochronological characteristics of all the main stages of OCVB magmatism were comprehensively studied by U-Pb SHRIMP and ID-TIMS zircon dating (86 samples) and 40Ar/39Ar analysis (73 samples). In general, a discontinuous character was established for the OCVB magmatism from the middle Albian to the early Campanian (106–77 Ma). The volcanism is laterally asynchronous. There are several peaks of volcanism with modes at approximately 105, 100, 96, 92.5, 87, 82, and 77 Ma. The Coniacian-Santonian peaks correspond to the most extensive stages of the middle and late cycles of felsic volcanism. A decreases and a hiatus in magmatic activity were reconstructed for the end of the Cenomanian and the beginning of the Turonian. The volcanism was terminated by plateau basalts with ages of 76–78 Ma, which mark a change in the geodynamic setting from frontal subduction to the regime of a transform margin with local extension in zones normal to the slip direction. A catastrophic character of eruptions with rather narrow ranges of volcanism (<2 Myr) were established taking into account new reliable age estimates for some individual large calderas. The accumulation rate of volcanic materials in such structures was up to 0.15–0.36 km3/yr and even higher.
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