Preparation, De-colorization, and characterization of protein isolate from Silflower (Silphium integrifolium Michx), an emerging perennial crop with food application potentials.

EaglePlex: Three STR multiplex panels optimized and validated for forensic identification and sex determination of Bald Eagles (Haliaeetus leucocephalus) and Golden Eagles (Aquila chrysaetos ).

Effect of European and North American poultry housing design and manure management on ammonia emission factors.

Epistemic injustice in healthcare professional practice: A scoping review.

Update to RIFM fragrance ingredient safety assessment, γ-hexalactone, CAS Registry Number 695-06-7.

Update to RIFM fragrance ingredient safety assessment, myristic acid, CAS Registry Number 544-63-8.

Update to RIFM fragrance ingredient safety assessment, naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-, CAS Registry Number 6790-58-5.

We aimed to estimate the prevalence of clinical and modifiable sociodemographic characteristics of individuals from ethnic minority backgrounds who died by suicide and, where possible, compare them to the majority population. Databases were searched for studies published between 01/01/2000-19/12/2023. Absolute and relative prevalence estimates of characteristics were reported by minority group (Indigenous; migrant; other ethnic minority) then stratified by continent and, where applicable, migrant sub-type and ethnicity. A narrative synthesis was conducted with moderate-high quality studies. We identified fifty-seven studies across 16 countries; the majority from North America, Europe and Oceania. When examining moderate-high quality evidence, there were generally limited numbers of studies reporting the prevalence of each characteristic by ethnic minority status, especially for social factors. Based on the available data, we found a high prevalence mental health problems among people who died by suicide from Indigenous (20.8-60.7%), migrant (37.2-42.9%) and other ethnic minority (29.9-37.3%) backgrounds. However, people from Asian/Pacific Islander, Black and Hispanic backgrounds were less likely to have mental health problems reported compared to majority populations. Indigenous people and migrants generally had lower contact with mental health services compared to majority groups. We also found evidence of a lower prevalence of depression and higher prevalence of alcohol and substance use problems among Indigenous compared to non-Indigenous individuals, and greater levels of economic disadvantage among migrants compared to non-migrants. Our findings highlight differences in the characteristics of people who die by suicide based on ethnicity and migration status and identify potential targets for research and suicide prevention strategies.

A comprehensive review of resistome profiles in ocular pathogens: Insights into Pseudomonas aeruginosa and emerging resistance trends.

The experiences of psychotherapies for post-traumatic stress disorder in children and adolescents: A meta-synthesis of qualitative literature.

Global breast cancer incidence, mortality, and survival among indigenous women: A systematic review and meta-analysis.

There is a disparity between the importance of radiation oncology (RO) to cancer care and the research activity that underpins it. This may relate to inadequate availability of, or barriers within, residency research training. This scoping review sought to characterize the barriers and enablers to RO research training, and to summarize relevant training pathways. Systematic Medline and Embase searches were conducted using "RO", "research", "training", and related terms, to identify reports published between 2010 and 2025. Manuscripts were screened using predefined inclusion and exclusion criteria to select those describing research initiatives, and barriers and enablers to resident-level research. These features were extracted along with country of origin and study design parameters. Of 1745 identified manuscripts, 54 were included. Most reports originated from North America (n = 24/54; 44.4 %), Europe (n = 12/54; 22.2 %) and Australasia (n = 8/54; 14.8 %). A majority were survey-based studies (n = 27/54; 50.0 %) or observational cohort analyses (n = 10/54; 18.5 %). We identified seven countries with mandated resident-level research training and three regions/countries with RO-specific physician scientist training programs. These varied from integrated training schemes that include higher research degree completion, to short-interval initiatives. Five programs were supported by metrics detailing their impact. Reported enablers and barriers demonstrated a subtle geographic variation but included protected time and funding, mentorship and attainment of research skills. There is global variation in research training during RO residency but numerous shared enablers and barriers. These data provide shared best practice and a scaffold on which national and international societies can build improved research training pathways to redress the radiation research deficit.

The family Onchocercidae, or filarioid nematodes, comprises common vector-borne parasitic worms that can infect, among other vertebrates, wild North American ruminant ungulates. Infection is a product of the available hosts and vectors distributed in viable ecosystems that permeate throughout the North America (i.e., Canada, United States, and Mexico) and Central America (i.e., Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, and Panama). The formation of these host-parasite assemblages can produce serious to no apparent clinical signs for the infected host animal depending on a multitude of factors. Overall, the scope of our knowledge regarding filarioid nematode infection of North American wild ruminant ungulates remains spotty and neglected throughout the scientific literature. However, reviewing these details provides a foundation for important biological, historical, ecological, and one health relevant questions. Analysis of the current scientific literature reveals that, at this time, nine out of fourteen wild North American ruminant ungulates can be infected with at least one species of filarioid worm. This includes four genera of known Onchocercidae species circulating within the North and Central American ecosystems: Elaeophora, Onchocerca, Rumenfilaria, and Setaria.

Active post-vaccination surveillance is vital for ensuring vaccine safety, particularly in monitoring Adverse Events of Special Interest (AESIs). This scoping review synthesises evidence on methodologies employed in active surveillance studies, with a focus on influenza and COVID-19 vaccines. Literature was identified via PubMed, Embase, Web of Science, Scopus, Google Scholar, and manual searches, using key terms including influenza, COVID-19, vaccine, and AESI. Two authors independently screened studies and extracted data on study characteristics, methods, and outcomes. Findings were synthesised narratively and presented in tables and figures, following the PRISMA-ScR guideline. Of 427 included studies, most were published after 2020 (74.0%) and focused on COVID-19 vaccines (69.3%), particularly mRNA platforms (51.3%). The majority were conducted in North America and Europe, with 85.5% from high-income countries; multinational studies accounted for 6.6%, and single-centre studies with national or subnational coverage for 63.0%. Cohort designs predominated (40.5%), mostly retrospective (74.2%), utilising registries (24.0%) and electronic health records (22.4%), including artificial intelligence for signal detection and prediction (2.7%). Nearly half (49.6%) linked multiple data sources, though outcome verification was reported in fewer than half (45.9%). Incidence rates (16.5%) and risk/hazard ratios (14.8%) were the most reported measures. Neurological (21.8%) and cardiac (21.3%) AESIs, particularly Guillain-Barré Syndrome and myocarditis, were most frequently investigated. Active surveillance for vaccine safety has increased but remains concentrated in high-income countries. Methodological approaches to detection, verification, and validation vary widely. Introducing active surveillance methodologies in low- and middle-income countries is crucial to achieving more equitable global monitoring of vaccine safety.

Spatiotemporal co-occurrence and shared exposure profiles of adolescent depressive disorders and asthma worldwide and in China (GBD 2021, 1990-2021): an ecological study with bidirectional two-sample Mendelian randomization.

The genus Carnus (family Carnidae, Order Diptera) comprises five species of small-bodied and blood-sucking flies that parasitize nestlings of wild bird species. Almost all species in this genus are restrictely distributed across different continents in the Northern Hemisphere, particularly Carnus hemapterus, which is a widespread ectoparasite of many bird species. Here, we report C. hemapterus parasitizing wild birds in central Argentina, resulting in the first record for the species in the entire Southern Hemisphere. Individual flies of C. hemapterus were found in nestlings of two bird of prey species, the American kestrel, already recorded as a host of C. hemapterus in North America, and the Chimango caracara, a new host species for this ectoparasite. Consistent with the species' life cycle, flies were observed only in nestlings but not in adult individuals captured in the same breeding areas. Besides the plausible reasons that could explain this new report, it significantly updates the global distribution for this ectoparasite taxon. Therefore, this record should draw the attention to ornithologists and parasitologists from large regions of the global South, which include some of the most important avian biodiversity host-spots, to this new ectoparasite-host interaction, which may affect a significant number of bird species and warrants investigation of its physiological and ecological impacts. Furthermore, beyond its role as an avian ectoparasite, C. hemapterus is involved in complex interespecific interactions, serving as a host for parasitoids and participating in multitrophic food webs within bird nests, which clearly warrant further research.

Human babesiosis is an emerging disease as more cases are being reported worldwide. Most cases in Europe are caused by Babesia divergens, whereas most cases in North America are due to Babesia microti. While B. microti is also found throughout Europe, it appears to be less pathogenic. We generated high-quality nuclear and organellar genome assemblies of two B. divergens and two B. microti isolates from Germany by long-read sequencing and compared them with each other and with the reference RI B. microti from the US. Variants of VESA1 (variant erythrocyte surface antigen 1) and secreted antigen 1/3 dominated the genes of the B. divergens isolates. The B. microti isolates and RI B. microti lacked VESA1. However, the B. microti isolates were different by their lack of 37 other proteins found in RI B. microti. These RI-specific proteins were intracellular, secreted, and membrane-bound. The lack of one or more of these genes by the new B. microti isolates may be the reason for why US strains are more pathogenic than B. microti from Europe. The ability of B. divergens to evade the immune system using VESA1, perhaps in combination with some secreted antigens, may be responsible for its higher pathogenicity compared with the European B. microti strains. This study has improved our understanding of the pathogenesis of babesiosis, and the new genomic data provided here has increased the repertoire of available genomic information about Babesia, especially since our new B. microti genomes are the first from Europe.

Avian malaria and invasion success: Contrasting infection patterns in two introduced Eurasian sparrows in North America (Passer domesticus and Passer montanus).

Biomarker recall and understanding among people living with metastatic breast cancer - results from an international patient survey.

Cross-border tourism in North America: A hybrid deep learning framework with macroeconomic indicators