Abstract The purpose of this paper is to prove some fixed point results dealing with a system of nonlinear equations defined in an angelic Hausdorff locally convex space ( X , { | ⋅ | p } p ∈ Λ ) (X,\{\lvert\,{\cdot}\,\rvert_{p}\}_{p\in\Lambda}) having the 𝜏-Krein–Šmulian property, where 𝜏 is a weaker Hausdorff locally convex topology of 𝑋. The method applied in our study is connected with a family Φ Λ τ \Phi_{\Lambda}^{\tau} -MNC of measures of weak noncompactness and with the concept of 𝜏-sequential continuity. As a special case, we discuss the existence of solutions for a 2 × 2 2\times 2 block operator matrix with nonlinear inputs. Furthermore, we give an illustrative example for a system of nonlinear integral equations in the space C ( R + ) × C ( R + ) C(\mathbb{R}^{+})\times C(\mathbb{R}^{+}) to verify the effectiveness and applicability of our main result.