Nonclinical Sample Of Young Adults Research Articles

Serum 25-Hydroxyvitamin D Concentrations and Depressive Symptoms among Young Adult Men and Women

There has been an increased interest in the role of vitamin D in depression; however, there have been few studies conducted in younger population groups. Our aim was to investigate the association between vitamin D status and depressive symptoms in a non-clinical young adult sample living in Dunedin, New Zealand. A cross-sectional sample of 615 young adults completed a questionnaire including demographics and the Centre for Epidemiological Studies Depression Scale (CES-D). Height, weight and a blood sample for 25-hydroxyvitamin D [25(OH)D] was obtained. Serum 25(OH)D was used to predict depression scores, adjusting for potential confounders including time spent outdoors for 13 consecutive days, BMI, age, sex and ethnicity. Prevalence of low vitamin D was high even in this age group, and serum 25(OH)D was negatively associated with depression symptoms before and after adjustment. When investigating the relationship between the presence versus absence of depressive symptoms and quartiles of 25(OH)D, participants in the lowest quartile were more likely to report depressive symptoms compared with those in the highest quartile. Although our findings suggest that vitamin D is a predictor of depression symptomatology, even when controlling for time spent outdoors, a randomised controlled trial in this young adult target group is needed to confirm the association.

A Multifaceted Assessment of Emotional Tolerance and Intensity in Hoarding

Hoarding is characterized by emotionally reinforced saving behaviors, which often combine with excessive acquisition to give rise to clutter, distress, and impairment. Despite the central role emotional processes are thought to play in hoarding, very little research has directly examined this topic. There is suggestive evidence linking hoarding with several facets of emotional intolerance and avoidance, though one key limitation of this past research has been the exclusive reliance on self-report questionnaires. The aim of the current study was to conduct a multimethod investigation of the relationship between hoarding and perceptions of, and cognitions about, negative emotional states. A large unselected sample of nonclinical young adults (N=213) completed questionnaires, behavioral tasks, and a series of negative mood inductions to assess distress tolerance (DT), appraisals of negative emotions, and emotional intensity and tolerance. Hoarding symptoms were associated with lowered tolerance of negative emotions, as well as perceiving negative emotions as more threatening. Individuals high in hoarding symptoms also experienced more intense emotions during the mood inductions than individuals low in hoarding symptoms, though there was no association with poorer performance on a behavioral index of DT. Across measures, hoarding was consistently associated with experiencing negative emotions more intensely and reporting lower tolerance of them. This relationship was particularly pronounced for the difficulty discarding and acquiring facets of hoarding. Our results offer initial support for the important role of emotional processes in the cognitive-behavioral model of hoarding. A better understanding of emotional dysfunction may play a crucial role in developing more effective treatments for hoarding.

Childhood and current ADHD symptom dimensions are associated with more severe cannabis outcomes in college students

BackgroundNumerous studies have shown that attention deficit/hyperactivity disorder (ADHD) is associated higher risk of cannabis use disorders (CUD). However, these studies are limited in that most did not: (a) differentiate the role of hyperactivity–impulsivity (HI) and inattention (IN); (b) control for associated psychopathology; and (c) consider more fine-grained CUD-related measures. Our aim was to clarify the unique and interactive contributions of inattention and hyperactivity symptoms to age of cannabis initiation and DSM-IV cannabis dependence, craving, and severity of problems related to cannabis use while statistically controlling for symptoms of comorbid psychopathology in a non-clinical sample of young adults. MethodsCannabis variables, current use of cigarettes and alcohol, current and childhood ADHD, and comorbid internalizing and externalizing psychopathology were assessed in 376 male and female undergraduates. ResultsResults indicate that current and childhood IN were independently associated with more severe cannabis use, craving, and problem use-related outcomes in young adulthood (p's<.01) and that childhood HI symptoms were associated with earlier initiation of cannabis (p<.01). Further, current IN symptoms moderated the relationships between level of use and more severe outcomes (p's<.01), such that higher IN strengthened positive associations among use and problem cannabis use. Associations with ADHD symptom dimensions and current use of alcohol and cigarettes were also present. ConclusionsThus, current and childhood inattention symptoms as well as childhood hyperactive–impulsive symptoms emerged as significant factors in cannabis-related outcomes in young adults, even after statistically controlling for important confounding variables.

Alexithymia and drinking in young adults: The role of alcohol-related intrusive thoughts

Alexithymia refers to difficulties identifying and describing emotions, an externalised thinking style and a lack of imagination. Alexithymia has been linked to heavier drinking in community samples and is strongly associated with alcohol use disorders. Among patients undergoing treatment for alcohol dependence, alexithymia is associated with more intrusive thoughts about drinking. The present research asked whether this may also be the case in a non-clinical sample of social drinkers and whether such intrusive thoughts mediate the relationship between alexithymia and drinking. Participants were 113 university undergraduates aged 18–30years who completed self-report indices of alexithymia (Toronto Alexithymia Scale-20, or TAS-20), drinking behavior (Alcohol Use Disorders Identification Test, or AUDIT), anxiety (Beck Anxiety Inventory, or BAI), sensitivity to punishment (SP scale of the Sensitivity to Punishment and Sensitivity to Reward scale), frontal lobe dysfunction (Frontal Systems Behavior Scale, or FrSBe), and intrusive thoughts about drinking (the Cognitive-Emotional Preoccupation with alcohol or CEP scale of the Temptation and Restraint Inventory). As predicted TAS-20 scores were significantly positively correlated with scores on AUDIT, CEP, BAI, SP, and FrSBe scales. CEP mediated the association between TAS-20 and AUDIT. Similar to those with alcohol dependence, alexithymic characteristics are related to intrusive thoughts about drinking which may significantly influence drinking behavior even in a non-clinical sample of young adults at university.

Dimensionality of the Wisconsin Schizotypy Scales-Brief Forms in College Students

Wisconsin Schizotypy Scales are one of the most used measuring instruments for the assessment of psychometric risk for psychosis. The main goal of the present study was to analyze the internal structure of the Wisconsin Schizotypy Scales-Brief (WSS-B) forms and the reliability of the scores in a large sample of college students. The final sample was comprised by a total of 1349 students, 288 males, with a mean age of 20.48 years (SD = 2.58). The results indicated that the WSS-B scores presented adequate psychometric properties. Cronbach's alfa coefficient for total scores in WSS-B ranged from 0.86 to 0.93. Analysis of the internal structure of the WSS-B, through confirmatory factor analysis and exploratory structural equation modeling, yielded a four factor solution (Magical Ideation, Perceptual Aberration, Social Anhedonia, and Physical Anhedonia) as the most adequate. Statistically significant differences in mean scores of WSS-B by sex were found. These results provided new validity evidence of the WSS-B scores in an independent sample of nonclinical young adults. The WSS-B seems to be useful, brief, and easy to administrate for the screening of extended psychosis phenotype in the general population.

Altered Functional Brain Connectivity in a Non-Clinical Sample of Young Adults with Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is characterized by symptoms of inattention and hyperactivity/impulsivity that often persist in adulthood. There is a growing consensus that ADHD is associated with abnormal function of diffuse brain networks, but such alterations remain poorly characterized. Using resting-state functional magnetic resonance imaging, we characterized multivariate (complex network measures), bivariate (network-based statistic), and univariate (regional homogeneity) properties of brain networks in a non-clinical, drug-naive sample of high-functioning young men and women with ADHD (nine males, seven females) and a group of matched healthy controls. Data from our sample allowed the isolation of intrinsic functional connectivity alterations specific to ADHD diagnosis and symptoms that are not related to developmental delays, general cognitive dysfunction, or history of medication use. Multivariate results suggested that frontal, temporal, and occipital cortices were abnormally connected locally as well as with the rest of the brain in individuals with ADHD. Results from the network-based statistic support and extend multivariate results by isolating two brain networks comprising regions between which inter-regional connectivity was significantly altered in the ADHD group; namely, a frontal amygdala-occipital network and a frontal temporal-occipital network. Brain behavior correlations further highlighted the key role of altered orbitofrontal-temporal and frontal-amygdala connectivity for symptoms of inattention and hyperactivity/impulsivity. All univariate properties were similar between groups. Taken together, results from this study show that the diagnosis and the two main symptom dimensions of ADHD are related to altered intrinsic connectivity in orbitofrontal-temporal-occipital and fronto-amygdala-occipital networks. Accordingly, our findings highlight the importance of extending the conceptualization of ADHD beyond segregated fronto-striatal alterations.

Sometimes a Bear is Just a Bear: No Evidence of Nonclinical Adult Toy Animal Ownership Indicating Emotion Dysregulation

Although some studies of clinical populations suggest an association of adult toy animal ownership with personality disorder, studies of nonclinical populations have been lacking. In a nonclinical young adult sample (N = 148), we found no association of toy animal ownership with use of immature, mature, or neurotic defense mechanisms; avoidant or anxious attachment style; trait conscientiousness; heart rate variability (an index of self-regulatory strength); or social desirability responding. The results do not provide evidence for an association of adult nonclinical toy animal ownership with psychological or psychophysiological indices of immaturity, conscientiousness, insecure attachment, or lack of self-regulatory strength.

Deliberate self‐harm behavior among Italian young adults: Correlations with clinical and nonclinical dimensions of personality.

This study aims to explore rates of deliberate self-harm (DSH) behaviors and their psychological and psychopathological correlates within a sample of nonclinical young adults (N = 365; 63% women; M age = 23 ± 4.06). Participants completed the Deliberate Self-Harm Inventory and other self-report questionnaires assessing clinical (borderline personality, dissociative, and depersonalization traits) and nonclinical (body perception, behavioral inhibition and activation, cognitive emotional regulation, and the Big Five traits) dimensions of their personality. The rate of DSH in the present sample was 39%, comparable to that found in previous studies of young adults in other countries. Further, consistent with past research, DSH was found to be associated with clinical dimensions of personality pathology, including borderline personality and dissociative symptoms. Finally, results revealed an association between DSH and nonclinical dimensions of personality, including the behavioral activation dimension of fun-seeking, more negative body perception and lower body protection, the use of more nonadaptive cognitive strategies for regulating emotions, higher levels of openness to experience, and lower levels of emotional stability. This pattern of results is consistent with those found for other impulsive behaviors and impulse control disorders.

Biological sex and menstrual cycle phase modulation of cortisol levels and psychiatric symptoms in a non-clinical sample of young adults

Prior research examined the complex, bidirectional interplay of the hypothalamic–pituitary–adrenal (HPA) and hypothalamic–pituitary–gonadal axes and their roles in (clinical) cognitive/behavioral functions. Less well understood are contemporaneous relationships in non-clinical samples. This pilot study explored cortisol in relation to psychiatric symptoms/personality as a function of self-reported menstrual cycle phase and sex differences in a non-clinical, young adult sample. Consistent with literature and hypotheses, cortisol levels were lowest during early-follicular, intermediary during late-follicular, and highest during mid-luteal phases (not significant), and greater among males than early-follicular females. An acute stressor uniformly affected cortisol across phases and sex, though magnitude and time course differed. Psychiatric symptoms were greater among early-follicular/late-follicular females versus males, and early-follicular and/or late-follicular versus mid-luteal. Contrary to hypotheses, positive psychotic-like symptoms were greater among males than (mid-luteal) females. Cortisol inversely related to early-follicular symptoms, and directly related to late-follicular/mid-luteal symptoms. Results suggest menstrual cycle phase modulates non-clinical psychiatric symptomatology and HPA activity. Findings tentatively bolster a dimensional/continuum model of psychopathology with implications for understanding neurobiological underpinnings and risk/protective factors for mental/physical health conditions, particularly those marked by sex differences and neuroendocrine dysfunction (depression/schizophrenia/Alzheimer's/multiple sclerosis). We speculate a dose–response cortisol effect on symptoms, modulated by endogenous gonadal hormones via gene expression.

Psychotic experience subtypes, poor mental health status and help‐seeking behaviour in a community sample of young adults

Different subtypes of psychotic experiences (PEs) have been identified in clinical and non-clinical samples. Researchers have considered these PEs to either be variations of personality or expressions of vulnerability to psychotic disorder. This study aimed to determine which particular subtypes of PEs were more likely to be associated with poor mental health status and help-seeking behaviour in a non-clinical sample of young adults. The study was conducted on a community sample of 997 young adults. The prevalence of PEs and distress was measured using the community assessment of psychic experiences (CAPE), depressive and anxiety symptoms were measured using Beck depression inventory-II and Beck anxiety inventory, and general functioning was measured using the general health questionnaire-12. Factorial analysis of the CAPE positive dimension was conducted and correlations between factors and clinical variables were analysed. Four PE subtypes were identified: perceptual abnormalities, persecutory ideas (PI), bizarre experiences, and magical thinking. At least one high frequency PI was endorsed by 60.8% (n = 606) of the sample and proved to be significantly associated both with poor mental health status and help-seeking behaviour. PEs subtypes are differentially associated with various markers of poor mental health status. PI seem to have stronger psychopathological significance than other subtypes of PEs. Further longitudinal studies are required to extend these findings.

Factor Invariance of Psychometric Schizotypy in Spanish and American Samples

The present study extended recent work examining the factor structure underlying the Wisconsin Schizotypy Scales by examining the factor invariance of this structure in Spanish and American nonclinical samples of young adults. A series of confirmatory factor analyses were conducted with 547 Spanish and 2,171 American young adults. Consistent with prior work, the best fitting model in both samples was a two-factor model with positive and negative schizotypy dimensions. Furthermore, the factor structure was invariant across the two samples. The findings support the construct validity of a multidimensional model of schizotypy and the use of psychometric inventories to assess these dimensions.

Mental state decoding abilities in young adults with borderline personality disorder traits.

Previous studies have demonstrated that patients with borderline personality disorder (BPD) tend to misattribute malevolence to benign social stimuli, including facial expressions. Yet, facial emotion recognition studies examining those with BPD have yielded mixed results, with some studies showing impaired accuracy and others demonstrating enhanced accuracy in the recognition of emotions or mental states. The current study examined the ability to decode mental states from photographs of just the eye region of faces in a nonclinical sample of young adults who exhibited BPD traits (high BPD) compared with those who did not (low BPD). Group differences in mental state decoding ability depended on the valence of the stimuli. The high-BPD group performed better for negative stimuli compared with the low-BPD group, but did not perform significantly different from the low-BPD group for stimuli of neutral or positive valence. The high-BPD group also demonstrated a response bias for attributing negative mental states to facial stimuli. In addition, findings suggested that the group difference in accuracy for negative stimuli could not be explained by response bias, because the group difference in response bias for negative stimuli did not reach significance. These findings suggest that BPD traits may be associated with enhanced ability to detect negative emotions and a bias for attributing negative emotions to nonnegative social stimuli.

Eysenck’s model of personality and psychopathological components in right- and left-handers

The link between handedness, personality, and psychopathology remains unclear. The objective of this study is to investigate in right- and left-handers the link between the Eysenck Personality Questionnaire (EPQ) scores and psychopathology status in a non-clinical sample of young adults. The EPQ, the Symptom Checklist 90 and the Edinburgh Handedness Inventory were completed by 84 normal young adults, 43 left-handers (20 males) and 41 right-handers (21 males). Canonical correlation analysis revealed that right-handers exhibited a positive association between the EPQ-neuroticism score and the symptom-fields of obsessive–compulsive, anxiety, depression and hostility. In left-handers, the EPQ-neuroticism score was positively associated with the symptom-fields of depression, psychoticism, paranoid ideation, anxiety, interpersonal sensitivity, phobic anxiety, hostility, and somatisation. Additionally, right-handers showed a protective effect of the combination of high EPQ-extraversion with low EPQ-psychoticism on the development of four psychopathology symptom-fields, namely interpersonal sensitivity, depression, psychoticism, and obsessive–compulsive behavior. These findings suggest that personality patterns, such as high levels of neuroticism, in relationship to handedness may induce phenotypic psychopathological variations.

‘Bright side’ and ‘dark side’ hypomania are associated with differences in psychological functioning, sleep and physical activity in a non-clinical sample of young adults

BackgroundNo research has yet focused on hypomanic states in non-clinical early adult populations. The aim of the present study was therefore to assess hypomania in a large non-clinical sample of young adults. MethodsA total of 862 participants (639 females and 223 males; mean age: M=24.67; SD=5.91) took part in the study. They completed a series of validated self-report questionnaires assessing hypomania (HCL-32) and other aspects of psychological functioning, sleep, stress, quality of life, cognitive–emotional elaboration of pain, self-efficacy, and physical activity. ResultsBased on the HCL-32, 19% of the participants (n=169) were categorized as currently being in a hypomanic state. Of those, 57.6% were classified as “active/elated” (‘bright side’), whereas 42.4% were classified as “irritable/risk-taking” (‘dark side’). Compared to non-hypomanic participants and the ‘bright side’ group, ‘dark side’ hypomanic participants reported more depressive symptoms, sleep disturbances, somatic complaints, perceived stress, negative coping strategies, and lower self-efficacy. By contrast, ‘bright side’ hypomanic participants had lower stress scores, more positive self-instructions, and higher levels of exploration, self-efficacy, and physical activity. LimitationsA cross-sectional design was adopted, assessing university students, who may not be representative of the stage of early adulthood. ConclusionsThe present results underscore the notion of a continuity between a mood state and both favorable (‘bright side’) and unfavorable (‘dark side’) hypomanic states. In early adulthood, ‘bright’ and ‘dark side’ hypomania differs with respect to physical activity, psychological functioning and sleep.

Biomarkers, population-based studies and a proof of principle investigation in pharmacotherapy

Dear colleagues, The current issue of the European Archivesof Psychiatry and Clinical Neuroscience offers a selection of key topics currently discussed in psychiatric research ranging from neurobiological findings to population-based as well as proof of principle studies. The term “biomarkers” is often not used properly in neuroscience as pointed out in the Letter to the Editors by Martins-de-Souza [1]. As outlined in this short article, there is an explosion of the term “biomarker”, which is often used for “a differentially expressed” protein discovered as potentially related to some disease in a small sample. The author suggests to be more cautious when using this term and instead suggests to use “potential biomarkers” or “biomarker candidate” as a better and clearer name. One of those fields with potential new biomarkers is the epidemiology of psychoses. Related to that, Steiner et al. [2] describe in their well-designed paper that in acute paranoid schizophrenia, there might well be reduced T-cell defense and a shift toward B-cell immunity, which normalizes in the response to treatment. Importantly, they point out that in addition to the disease stage or subtype of the illness medication, cigarette smoking and stress are important co-factors. Researching cognitive dysfunction in schizophrenia has moved to test circuit-specific tasks in this disorder. The paper by Zilles et al. [3] moves this way identifying subgroups of patients with schizophrenia showing different patterns of selective deficits in working memory components. These deficits are present in tasks requiring only the maintenance of verbal or visuospatial information. In contrast to an obviously global working memory deficit, individual analysis revealed differential patterns of working memory impairments in subgroups of patients with schizophrenia. Trying to connect brain changes in major psychiatric disorders like depression with pathophysiological mechanisms is desired but difficult. Candidates for hippocampal volume reduction in depressed patients are the neurotrophic factors. Along these lines, Eker et al. [4] found a correlation of serum BDNF levels with hippocampal volumes in first-episode, medication-free depressed patients. This correlation could not be revealed in the control sample, and more interestingly, there was no significant volumetric difference between the depressed patients and the control subjects pointing to a very subtle volumetric change related to BDNF secretion. Subsequently, two studies were selected using large samples of healthy subjects. In the first study by Moraes et al. [5], the mini-mental state examination (MMSE) was applied in a sample of 2,708 adults, aged 60 years and older. High scores on a depression scale, high scores on a memory complaints scale and low socioeconomic levels were associated with poorer performance on the MMSE. This underlines the importance of some sociodemographic and health variables influencing MMSE performance and furthermore pointing at the increasingly important trajectory between mood disorder and the later development of dementia. In the second study by Brand et al. [6], 862 participants completed a series of validated self-report questionnaires assessing sleep, quality of life, depressive symptoms and cognitive-emotional elaboration of pain. For this non-clinical sample of young adults, the bi-directional relation between poor sleep and increased cognitive-emotional elaboration of pain was proven. In an open proof of principle study by Perugi et al. [7], it was tested whether adjunctive valproate treatment might ameliorate panic disorder symptoms with a lifetime comorbid bipolar disorder or patients otherwise resistant to antidepressants. All patients were evaluated baseline and at least every three month and followed for a period of three years. According to the results, valproate seems to be an effective and a well-tolerated adjunctive treatment in panic disorder patients who are resistant to antidepressant therapy or have bipolar disorders in comorbidity. This supports the hypothesis that the resistance to antidepressants might well be related to mood instability.

The Obsessive Compulsive Drinking Scale Is a Valid Measure of Alcohol Craving in Young Adults

Alcohol craving is associated with greater alcohol-related problems and less favorable treatment prognosis. The Obsessive Compulsive Drinking Scale (OCDS) is the most widely used alcohol craving instrument. The OCDS has been validated in adults with alcohol use disorders (AUDs), which typically emerge in early adulthood. This study examines the validity of the OCDS in a nonclinical sample of young adults. Three hundred and nine college students (mean age of 21.8 years, SD = 4.6 years) completed the OCDS, Alcohol Use Disorders Identification Test (AUDIT), and measures of alcohol consumption. Subjects were randomly allocated to 2 samples. Construct validity was examined via exploratory factor analysis (n = 155) and confirmatory factor analysis (n = 154). Concurrent validity was assessed using the AUDIT and measures of alcohol consumption. A second, alcohol-dependent sample (mean age 42 years, SD 12 years) from a previously published study (n = 370) was used to assess discriminant validity. A unique young adult OCDS factor structure was validated, consisting of Interference/Control, Frequency of Obsessions, Alcohol Consumption and Resisting Obsessions/Compulsions. The young adult 4-factor structure was significantly associated with the AUDIT and alcohol consumption. The 4 factor OCDS successfully classified nonclinical subjects in 96.9% of cases and the older alcohol-dependent patients in 83.7% of cases. Although the OCDS was able to classify college nonproblem drinkers (AUDIT <13, n = 224) with 83.2% accuracy, it was no better than chance (49.4%) in classifying potential college problem drinkers (AUDIT score ≥13, n = 85). Using the 4-factor structure, the OCDS is a valid measure of alcohol craving in young adult populations. In this nonclinical set of students, the OCDS classified nonproblem drinkers well but not problem drinkers. Studies need to further examine the utility of the OCDS in young people with alcohol misuse.

Suppressing the white bears interacts with anxiety sensitivity in the prediction of mood and anxiety symptoms

Suppression is a commonly used strategy to manage unwanted thoughts by attempting to actively remove them from awareness. However, research has shown that this cognitive strategy often results in the paradoxical effect of increasing the frequency of unwanted thoughts. While the association between thought suppression and mood and anxiety symptoms has been repeatedly demonstrated, relations between this cognitive strategy and other anxiety risk factors such as anxiety sensitivity (AS) are unexplored. Using a nonclinical sample of young adults ( N = 414), the current investigation sought to more thoroughly investigate the association between AS and thought suppression as well as explore their synergistic effect on anxiety symptomatology. As hypothesized, thought suppression and AS were positively associated. Moreover, AS and thought suppression interacted to predict elevated levels of panic and obsessive compulsive symptomatology.

The relation between sleep and pain among a non-clinical sample of young adults

Poor sleep is linked to poorer daily functioning and increased risk of psychiatric symptoms. With respect to pain, the relation is bi-directional; poor sleep exacerbates pain, while greater pain adversely affects sleep. Moreover, perception of pain is subject to cognitive-emotional processes. Surprisingly, no data are available from non-clinical samples of young adults. The aim of the present study was therefore to investigate the relation between sleep and pain as a function of quality of life and depressive symptoms in young adults. The direction of influence between sleep and pain was statistically tested with two different structural equation models (SEMs). A total of 862 participants (639 women, 223 men; mean age: 24.67; SD = 5.91) completed a series of validated self-report questionnaires assessing sleep, quality of life, depressive symptoms and cognitive-emotional elaboration of pain. Sleep, pain, quality of life, and depressive symptoms were interrelated. The first SEM suggested both a direct and an indirect influence of pain on sleep, whereas the second SEM suggested that sleep had only an indirect influence on pain. Irrespective of the SEM, the relation between sleep and cognitive-emotional elaboration of pain was mediated by quality of life and depressive symptoms. For a non-clinical sample of young adults, findings did support the bi-directional relation between poor sleep and increased cognitive-emotional elaboration of pain, though other cognitive-emotional processes such as depressive symptoms and quality of life should be taken into account.

Mood and personality-based models of substance use.

Mood and personality-based vulnerabilities have been extensively examined in patients with substance use disorders, but their relevance as models of etiology remains to be fully investigated. The present investigation examined mood and personality-based models of substance use in a nonclinical sample of young adults. Two-hundred and twelve individuals were assessed for personality and clinical characteristics and participated in computerized ambulatory monitoring of mood states and substance use over a 1-week period. Personality factors were strong predictors of substance use frequency over the previous 30 days, as well as of substance use in daily life using ambulatory monitoring. A linear increase was also observed in the intensity of novelty seeking and antisocial personality traits as a function of the social deviance of substances used. However, mood disorder history was related only to the use of illicit drugs other than cannabis, and fluctuations in mood states did not prospectively predict daily use of substances in a manner consistent with self-medication. Moreover, there was little evidence that personality characteristics moderated relations between mood states and substance use in daily life. The relevance of results for mood and personality models of substance use etiology is discussed.

Adult attachment, personality traits, and borderline personality disorder features in young adults.

Previous studies have demonstrated that insecure attachment patterns and a trait disposition toward negative affect and impulsivity are both associated with borderline personality disorder (BPD) features. According to attachment theory, insecure attachment patterns impart greater risk for the maladaptive personality traits underlying BPD. Hence, insecure attachment might be indirectly related to BPD through its association with these traits. The current cross-sectional study used structural equation modeling to compare two competing models of the relationship between adult attachment patterns, trait negative affect and impulsivity, and BPD features in a large nonclinical sample of young adults: (M1) attachment anxiety and avoidance are positively related to trait negative affect and impulsivity, which in turn, are directly associated with BPD features; and (M2) trait negative affect and impulsivity are positively related to attachment anxiety and avoidance, which in turn, are directly associated with BPD features. Consistent with attachment theory, M1 provided a better fit to the data than M2. However, only attachment anxiety, and not attachment avoidance, was significantly associated with negative affect and impulsivity. The results favored a model in which the relationship between adult attachment anxiety and BPD features is fully mediated by trait negative affect and impulsivity.