The thermistor was fabricated by filling the nematic liquid crystal (NLC) material IM95100-000 into a liquid crystal device with an interdigital electrode structure. In the temperature range of 25 °C-120 °C, the temperature response of the thermistor under different voltages was measured with a step length of 5 °C to study its performance. The experimental results show that the resistance value of the thermistor decreases exponentially with increasing temperature in the range of 25 °C-120 °C. The temperature resistance characteristics at different voltages can satisfy the Steinhart-Hart formula well and the nonlinear fitting coefficient can reach 0.999; under the voltage of 1 V, the total resistance percentage changes by 93.1%, the material constant B <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">25-120</sub> value can reach 3299.07 K, and the temperature coefficient of resistance (TCR) can reach 0.98%/K. As a temperature sensor, it is twice as sensitive as that without the interpolated electrode structure, and the sensitivity can be further improved as the temperature decreases. Through the stability and recovery measurements, it is found that the resistance has no obvious deviation, which verifies the possibility of long-term application of this thermistor.