National Action Research Articles

Express quantitative spectrophotometric determination of 2-(((3-(2-fluorophenyl)- 5-thio-4H-1,2,4-triazol-4-yl)imino)methyl)phenol as an active substance of a medicinal product for the treatment of mycoses

Foot fungus (Candida, molds, dermatophytes) is a fairly common problem. According to the WHO, one-fifth of the world’s population is affected by fungal skin diseases. The prevalence of mycosis of the feet, which affects every second person, is especially increasing. Such a pathology can appear quite unexpectedly and at an inappropriate time. Today, Ukraine is under aggressive pressure from its northern neighbor, and military personnel are not only constantly at risk of receiving combat injuries and wounds, but also due to active hostilities, they may not have access to the necessary hygiene products, get cold, overheat in the sun, or not have time to change their clothes in time. and shoes. The reality is the absence or delay of treatment; the disease progresses and can spread quickly. If mycosis has appeared in one soldier, it can quickly affect others. Therefore, the problem of providing medical and pharmaceutical care is an urgent issue today. Expanding the assortment of drugs with the above action will ensure the needs of the Armed Forces and civilian patients with this dermatological pathology. It will be able to optimize antifungal therapy regimens. For quite a long time, 1,2,4-triazole derivatives have been a promising class of organic compounds that attract the attention of scientists from various fields. It has been proven that 2-(((3-(2-fluorophenyl)-5-thio-4H-1,2,4-triazole-4-yl)imino)methyl)phenol has high antifungal activity. A potential medicinal product based on this medicinal substance can be used for the treatment of various dermatological diseases. To continue the creation of new effective dosage forms for the effective therapy of mycosis of the feet, the urgent task of today is the development of an express, accurate, reliable, and affordable method of quantitative determination of the substance under study. The aim of the work is to develop an express, sensitive and easy-to-implement UV-method for the quantitative determination of 2-(((3-(2-fluorophenyl)-5-thio-4H-1,2,4-triazole-4-yl)imino)methyl)phenol. Materials and methods. The research object is a working standard sample of 2-(((3-(2-fluorophenyl)-5-thio-4H-1,2,4-triazole-4-yl)imino)methyl)phenol provided by NUNVF, LLC “Brovapharma” according to the “Research and production technological regulations for the production of 2-(((3-(2-fluorophenyl)-5-thio-4H-1,2,4-triazol-4-yl)imino)methyl)phenol” developed based on scientific developed by the Ukrainian Military Medical Academy in conjunction with the National Military Medical Clinical Center “Main Military Clinical Hospital” (term of validity of the regulations until 12/31/2034). Isopropanol of grade “chemically pure” was used as a solvent. Analytical equipment: spectrophotometer Specord 200, electronic scales Radwag XA 210.4Y, class A measuring vessels. Results. An express, eco-friendly spectrophotometric method was developed for the quantification of 2-(((3-(2-fluorophenyl)-5-thio-4H-1,2,4-triazole-4-yl)imino)methyl)phenol in isopropanol area, having analytically maximum at 310 nm. The studied solutions are stable for 30 minutes. The analytical technique is linear in the range of concentrations 0.440–0.754 mg/100 ml (70–130 %). The detection and quantification limits were 5.80 % and 15.70 % respectively. The score was 0.76, according to the “greenness” icon of the analytical technique, using the tools AGREE. The prediction of the total uncertainty of the results of the developed method is 1.70 % (max∆As 2.00 %). The proposed method is relevant according to the requirements of the State Pharmacopoeia of Ukraine. Conclusions. Pharmaceutical development, introduction into industrial production and further prescribing by dermatovenerologists of an effective, safe, and harmless medicinal product will help to expand the range and reduce the level of high import dependence of the domestic market of medicinal products, which will create a more complete and balanced system of medicinal supply in Ukraine and optimize antifungal therapy schemes.

Deconcentrating regulation in low- and middle-income country health systems: a proposed ambidextrous solution to problems with professional regulation for doctors and nurses in Kenya and Uganda

BackgroundRegulation can improve professional practice and patient care, but is often weakly implemented and enforced in health systems in low- and middle-income countries (LMICs). Taking a de-centred and frontline perspective, we examine national regulatory actors’ and health professionals’ views and experiences of health professional regulation in Kenya and Uganda and discuss how it might be improved in LMICs more generally.MethodsWe conducted large-scale research on professional regulation for doctors and nurses (including midwives) in Uganda and Kenya during 2019–2021. We interviewed 29 national regulatory stakeholders and 47 subnational regulatory actors, doctors, and nurses. We then ran a national survey of Kenyan and Ugandan doctors and nurses, which received 3466 responses. We thematically analysed qualitative data, conducted an exploratory factor analysis of survey data, and validated findings in four focus group discussions.ResultsKenyan and Ugandan regulators were generally perceived as resource-constrained, remote, and out of touch with health professionals. This resulted in weak regulation that did little to prevent malpractice and inadequate professional education and training. However, interviewees were positive about online licencing and regulation where they had relationships with accessible regulators. Building on these positive findings, we propose an ambidextrous approach to improving regulation in LMIC health systems, which we term deconcentrating regulation. This involves developing online licencing and streamlining regulatory administration to make efficiency savings, freeing regulatory resources. These resources should then be used to develop connected subnational regulatory offices, enhance relations between regulators and health professionals, and address problems at local level.ConclusionProfessional regulation for doctors and nurses in Kenya and Uganda is generally perceived as weak. Yet these professionals are more positive about online licencing and regulation where they have relationships with regulators. Building on these positive findings, we propose deconcentrating regulation as a solution to regulatory problems in LMICs. However, we note resource, cultural and political barriers to its effective implementation.

Evidence-based policy-making in normatively divided policy fields: European Institute for Gender Equality, Agency for Fundamental Rights and Slovak policies tackling violence against women

In recent years, we have seen a shift towards soft law policy-making within EU gender equality policies, embracing a new rationale of evidence as a promising panacea for the ills of democratic deficit. This shift has been fostered by the establishment of the EU Agency for Fundamental Rights (FRA) and the European Institute for Gender Equality (EIGE), which both promote tools of benchmarking, ranking and good-practice sharing. Focusing on the relative impact of Europeanisation, this case study sheds light on the various processes of negotiating and resisting these indicator-based tools of policy-making by national actors in the field of gender-based violence. Gender-based violence is a normatively divided policy field in which actors struggle for limited resources. By viewing the accounts of the respondents through the framework of usage of Europe, we discuss the practices the actors engage in when employing the work of FRA and EIGE at the national level.

How smart and sustainable are the cities in Turkiye? - National policies and the enthusiasm level of the local governments

In the past decade, the importance of the smart city applications has gained popularity by the city governments to use their resources in an efficient and effective way, present better services and quality of life for their residents, make their cities more competitive, provide better disaster management. As the world has experienced crisis such as energy and grain in the recent past due to the COVID-19 pandemic and the war between Russia and Ukraine, the management of the resources has become more important for the countries and local governments, as well. In this study national government plans of Turkiye, such as Eleventh Development Plan and 2020–2023 National Strategy and Action Plan for Smart Cities, have been addressed as reference documents and the actions of some city governments, including the most populous city, Istanbul and the capital, Ankara, have been examined with the purpose of determining the level of smart city willingness. This study peruses the degree of enthusiasm of the local governments to become smart and maintain sustainable city services considering the main smart city characteristics. Based on the information gathered concerning the selected cities, it has been observed that the cities having populations quite lower than the great metropolitans such as Istanbul and Ankara are more enthusiastic and successful to provide services for their citizens that can be associated with the smart city concept.

Global approaches to tackling antimicrobial resistance: a comprehensive analysis of water, sanitation and hygiene policies

BackgroundUnsafe water, sanitation and hygiene (WASH) contributes to a high burden of disease and exacerbates factors that promote the development of antimicrobial resistance (AMR). Enforceable policies are foundational to curbing...

Evaluation to Determine Antibiotic Resistance Reduction in Gram-Negative Bacteria from 2019 to 2021 by the Saudi Arabia National Plan.

The main objective of this study was to investigate the three-year evaluation of antibiotic resistance (AR) of multi-drug-resistant organisms and extended-spectrum beta-lactamase (ESBL)-resistant rate of gram-negative bacteria in one of the largest hospitals by the Saudi Arabia Nation Plan. This study was conducted in the Department of Laboratory Medicine, in a private hospital in Riyadh City, Saudi Arabia, from January 2019 to December 2021 in 120-bed private hospitals. A total of 4700 gram-negative isolated organisms were obtained from the various specimens of the patients, and antibiotic sensitivity tests were performed. According to the manufacturer's instructions, the inoculum prepared was applied to two test cards, one for the identification system VITEK 2 ID-GNB and another for susceptibility testing antimicrobial susceptibility testing (AST) No. 12. The most common gram-negative bacteria isolated was Escherichia coli (2706/4700; 57.57%), followed by Klebsiella pneumoniae (905/4700; 19.25%) and Pseudomonas aeruginosa (395/4700; 8.40%). Escherichia coli's highest AR reduction was reported for cefotaxime (CTX) of 29% (295/1018; 29%, 172/818; 21%, 0/870; 0%) for 2019, 2020, and 2021, respectively. Except for Salmonella species, which displayed enhanced AR, the ESBL and multidrug-resistant (MDR) rates decreased significantly (p 0.05) for most bacteria. This study helps to understand the maximum number of gram-negative bacteria susceptible to the Saudi National Action Plan (SNAP) to decrease the prevalence of AR, ESBL, and MDR. To comprehensively understand SNAP's effectiveness, other trials involving gram-positive bacteria should be considered.

Human dog-mediated rabies in the Circle of Kati, Mali: An epidemiological situation analysis and the stakeholder’s knowledge regarding rabies and the One Health approach

Background and Aim: Human dog-transmitted rabies remains a serious public health issue in Mali despite efforts to mitigate it. Indeed, several stakeholders have implemented multiple initiatives for years. However, there is still a lack of cooperation among stakeholders. This study was conducted to capture situational data on rabies and One Health practices among key actors involved in the fight against rabies in Mali. Materials and Methods: Data from veterinary and medical services were collected for analysis. Data collection was based on a review of technical documents (epidemiology of rabies in animals and humans and activities conducted to tackle the disease) and stakeholder interviews (awareness of rabies and the One Health approach). Results: With regard to the epidemiological situation, the findings revealed unsatisfactory vaccination coverage in dogs and low suspected sample collection for laboratory diagnosis. In addition, only half of the exposed individuals received complete post-exposure prophylaxis. A survey carried out by experts in the fields of animal health, human health, and the environment indicated that only 22.47% were well aware of rabies and had never heard of the One Health approach. Overall, there was no significant association between knowledge and participant sector of origin (p > 0.05), highlighting the need for operationalization of the One Health approach in Mali. Conclusion: Therefore, an integrated national action plan for rabies control should be developed with a particular focus on capacity building, particularly in the area of the One Health core competencies. Keywords: epidemiology, multisectoral engagement, One Health, Public Health priority zoonoses, Stakeholders.

The Government's Role in Enforcing the Law Against Perpetrators of Terrorism

Purpose: The purpose of the research is to provide a comprehensive understanding of the government's role in countering terrorism in Indonesia, analyze the legal and institutional frameworks, and emphasize the significance of international collaboration in addressing the global nature of terrorism.
 
 Theoritical Framework: The theoretical framework for understanding counterterrorism dynamics in Indonesia integrates diverse perspectives. Drawing from criminology, the Routine Activity Theory explores root causes, emphasizing socio-political, economic, and ideological factors. The Legal Process Theory elucidates interactions within legal institutions, such as the Indonesian National Police, military, and BNPT. The framework advocates a holistic counterterrorism approach for societal security and global stability.
 
 Methodology: The research methodology combines normative juridical analysis with a thorough examination of legal literature and secondary data to provide a comprehensive understanding of the legal and conceptual framework underlying the government's role in countering terrorism in Indonesia.
 
 Findings: The Indonesian government has implemented a multifaceted strategy to combat terrorism, featuring specialized units like Densus 88 and the National Agency for Combating Terrorism (BNPT). Densus 88, part of the National Police, handles various terrorist threats, while BNPT formulates and implements national anti-terrorism policies. The establishment of the State Intelligence Agency (BIN) enhances intelligence capabilities. Recognizing terrorism's global nature, international cooperation is crucial. The study emphasizes the need for robust government policies, effective law enforcement, and collaboration to address terrorism's societal impact comprehensively.
 
 Research, Practical & Social implications: The research significantly contributes to academic understanding by comprehensively exploring terrorism, government policies, and law enforcement in Indonesia, employing a normative juridical methodology. With practical implications, it highlights the need for robust government policies, emphasizing the roles of key institutions like the Indonesian National Police, BNPT, and the military. Practical applications involve fostering collaboration, implementing preventive measures, and prioritizing international cooperation. Socially, the research underscores the government's vital role in ensuring societal security, promoting a collective sense of safety and resilience against terrorism.
 
 Originality/value: The study stem from its comprehensive exploration of terrorism, in-depth analysis of the government's role and legal institutions, highlighting international cooperation, and providing a holistic approach with practical policy recommendations. The integration of a normative juridical methodology further enhances the research's academic rigor and contributes to the understanding of legal aspects related to counterterrorism efforts.

Carbon Emission Mitigation: a Sustainable Transportation Perspective for Reforming the Law on Highways in Indonesia

Objective: This research aims to provide essential issues to be included in the draft of new regulations to revise Law Number 22 of 2009 concerning Road Traffic and Transportation. The transportation sector plays a vital role in social mobility in Jakarta. However, the negative impact of increasing carbon emissions reaching 171 air pollution standard index (APSI) cannot be accommodated by outdated laws and poses a significant challenge to the health of the environment and urban communities now and in the future. Theoretical framework: The theory used is Carbon Emission Disclosure. We will use some of this theory to explain and incorporate it into the plans for new regulations. Carbon Emission Disclosure (CED) is one part of carbon accounting, an organization's obligation to measure, acknowledge, record, present, and disclose carbon emissions. In this context, the government is responsible for CED. Carbon Emission Disclosure was measured using several items adopted from research. There are five broad categories relevant to climate change and carbon emissions: climate change risks and opportunities, greenhouse gas emissions, energy consumption, reduction of greenhouse gases and costs, and accountability of emission carbon. Method: The Method uses a qualitative approach using focus group discussions and is supported by participant observation. Sixteen stakeholders, policymakers, and eight private vehicle users participated in this study, providing diverse perspectives. Research starts May 18 to November 19, 2023. The research locus is in the city of Jakarta. Results and Conclusions: This study found six themes that were taken into consideration to be included in the draft of new regulations that will be drafted. Namely Motor Vehicle Policy is to reduce the amount of reduction in the impact of carbon emissions; policy on the impact of traffic jams and density, the impact of carbon emissions on population health; limiting vehicle emissions by implementing carbon accounting; zero-emission vehicles by supporting electric vehicles; future solutions and strategies, namely implementing a Carbon Capture, Utilization and Storage (CCUS) plan to reduce carbon emissions, and regarding the use of illegal drugs, alcohol, and several points proposed by field observation participants. Research implications: This study presents policy implications that the government can utilize to reduce the impact of carbon emissions through several parts of the CED concept, including reducing carbon emissions, high energy consumption in Jakarta can be reduced by electric vehicles, detailing emission reduction strategies, and comprehensively implementing accountability for carbon emissions serious about coal-based electricity companies around the city of Jakarta. The consequences of this strategy can range from policy formulation to developing new regulations that replace old laws. Originality/value: This research analyzes the paradigm shift, which still uses old laws to become new laws, by including the CED concept, which focuses on six themes from the results of this study. These changes can affect transportation management in Indonesia. This paradigm shift study is a new contribution because it can provide a deeper understanding of the evolution of transportation governance by reducing carbon emissions. This paradigm shift is expected to significantly shift private vehicle users to mass vehicles, reducing carbon emissions. On the other hand, the government has issued regulations President Number 61 of 2011 concerning the National Action Plan for Emission Reduction Greenhouse Gases. This regulation is issued to reduce carbon emissions. The challenge is that until now, the implementers have yet to implement it thoughtfully; its implementation is separate from the National Law and requires a solid will to include it in the new draft law as a single unit.

10-year level, trends and socio-demographic disparities of obesity among Ghanaian adults-A systematic review and meta-analysis of observational studies.

The double burden of malnutrition has assumed severer forms in Low and Middle Income Countries (LMICs) arising from sharper increases in prevalence rates of overweight and obesity in these countries compared to higher income countries. Considering that LMICs already have fragile health systems, the rising obesity levels may just be a ticking time bomb requiring expeditious implementation of priority actions by all global and national actors to prevent an explosion of cardiovascular disease related deaths. The aim of this systematic review and meta-analysis was to provide a current estimate of obesity and overweight prevalence among Ghanaian adults and assess socio-demographic disparities following the PRISMA guidelines. We searched Pubmed with Medline, Embase, Science direct and African Journals Online (AJOL) for studies on overweight and obesity published between 2013 and January 2023. Applying a quality effects model, pooled mean Body Mass Index (BMI) and prevalence of overweight and obesity were obtained from 42 studies conducted across all three geographical locations of Ghana with a combined sample size of 29137. From the analysis, the mean BMI of adults in Ghana was 24.7 kgm-2 while overweight and obesity prevalence was estimated as 23.1% and 13.3% respectively. Temporal analysis showed sharper increases in overweight and obesity prevalence from 2017/2018. Mean BMI (Females: 25.3kgm-2 vrs Males: 23.1 kgm-2), overweight (Females: 25.9% vrs Males: 16.5%) and obesity (Females: 17.4% vrs Males: 5.5%) prevalence were higher among females than males. Gender differences in mean BMI and obesity prevalence were both significant at p<0.001. Urban dwellers had higher mean BMI than their rural counterparts (24.9kgm-2 vrs 24.4kgm-2). Overweight (27.6% vrs 18.2%) and obesity (17.3% vrs 11.0%) prevalence were also higher in urban areas than in rural areas. Body weight indicators for the various geographical areas of Ghana were; southern sector: 25.4kgm-2, 28.9% and 15.4%, middle sector: 24.8kgm-2, 26.4% and 16.2% and northern sector: 24.2kgm-2, 15.4% and 8.5% for mean BMI, overweight and obesity prevalence respectively. The southern part of Ghana was similar to the middle part in terms of mean BMI, overweight and obesity but higher than the northern part. We conclude that overweight and obesity prevalence in Ghana has risen to high levels in recent years with women and urban dwellers disproportionately more affected. There is a possible implication for increased cardiovascular diseases and a generally poor quality of life for the people. Evidence-based public health interventions are needed to reverse the current situation.

The Future of School Health Education in the United States: An Ontology.

As summarized in this article, the widespread implementation of modern school health education (SHE) could become one of the most effective means available to improve the well-being of people in the United States and in other nations. However, the development and evolution of SHE largely remains unorganized, underdeveloped, and neglected by health and education agencies, policymakers, and the public. Essential to the development of any scientific discipline, scientists today use the word ontology to refer to efforts to organize knowledge in particular domains. A useful working definition of a scientific ontology is an explicit, formal specification of a shared conceptualization-a systematic set of shared terms and an explication of their interrelationships. Nine interdependent questions are outlined to help guide the development of an initial, broad, and actionable scientific ontology for SHE. Whether and how we respond to these questions arguably will determine the future of SHE research, policy, practice, and equity in the United States. An initial ontology might help conceptualize, inform, and facilitate more systematic and strategic local, state, national, and international deliberations and actions to improve SHE.

Rewarding mobility? Towards a realistic European policy agenda for academics at risk

This article maps from a critical and comparative perspective how scholars at risk are currently being integrated into the European research infrastructure, as well as in various EU and non-EU Member States. The focus is on three countries ranging from older to newer EU members to one non-EU member state—Hungary, Romania and the United Kingdom—as well as on EU-level organisations. We draw on twelve in-depth interviews conducted with key stakeholders involved in the process of academic migration (non-governmental organisations, EU and national level actors) to identify key issues concerning academics at risk. Finally, we call for a robust EU-level response to an issue that is currently inadequately addressed by national governments, professional associations and NGOs. As we argue, the focus on mobility as a factor supporting research excellence in the regular European research infrastructure can have negative unintended outcomes for scholars at risk. For many of them, rewarding mobility can entail the threat of losing their legal status in temporary places of migration. What is needed is a nuanced approach for scholars at risk in a diverse range of situations, which should involve closer cooperation between international academic bodies and EU policy makers, and complement support for those who need to escape to third countries with the offer of remote work in the country where they are able to obtain a secure residence permit.

Peatland restoration in Norway – evaluation of ongoing monitoring and identification of plant indicators of restoration success

Norway launched a national action plan on wetland restoration in 2016. So far, 90% of the restoration effort has been on peatland restoration, with about 140 mires restored so far. There are three main restoration goals stated in the action plan: 1) limit greenhouse gas (GHG) emission, 2) climate adaptation and 3) improved ecological condition. Quantifying the outcome of the restoration actions is necessary to evaluate whether the goals of the action plan are met. A vegetation monitoring protocol was suggested before restoration started and has been implemented at five restoration sites. As the peatland restoration effort in Norway is increasing, it is timely to evaluate if the data currently collected can measure peatland restoration outcome. We evaluate the monitoring protocol based on statistical analyses of the data collected at two sites, describe how indicator species can be identified using generalized composition data used as the basis for classifying habitats in Norway (EcoSyst framework), and suggest the way forward for peatland restoration monitoring in Norway. Data collected according to the monitoring protocol can document changes in species composition at restoration sites, but has limitations when the ecological complexity at the sites increases and reference sites are unavailable. We argue that adjusting the monitoring protocol will: 1) facilitate alignment with existing peatland research; 2) connect better with monitoring programs where data is collected applying EcoSyst framework principles; and 3) enable upscaling to cover the wide variation emerging in peatland restoration.

A qualitative study of the factors impacting implementation of the national action plan to contain antimicrobial resistance (2016-2020) in medical institutions.

Antimicrobial resistance (AMR) has emerged as a serious global public health crisis. In response, 2016, 14 ministries in China, under the leadership of the National Health Commission, collaboratively issued the National Action Plan (NAP) to Contain Antibacterial Resistance (2016-2020). The NAP outlines strategies for medical institutions to adopt stewardship and implement AMR control. The purpose of this study was to comprehend stakeholders' perceptions of the NAP and explore the factors that influence its implementation in medical institutions. Semi-structured interviews were conducted with practitioners from medical institution in March and April 2021. Interviews were audio-recorded, transcribed and analyzed using thematic analysis via the framework approach. Twenty practitioners, representing diverse roles (4 administrators, 7 clinicians, 3 microbiologists, 3 pharmacists, 3 nosocomial infection management personnel) from seven institutions, participated in the study. Substantial efforts have been undertaken to regulate the rational use of antibiotics and enhance the management of hospital infections. Participants demonstrated awareness and concern regarding antimicrobial resistance, with widespread support expressed for the NAP. Among all professions, there were varying opinions on whether they felt restricted in their daily work. The tertiary hospitals have established multidisciplinary cooperation mechanisms. Six main themes were identified as both barriers and facilitators to the implementation of the NAP in the medical institutions: individual factors, leadership, multidisciplinary collaboration, patient factors, trainingand culture. The capacity for administrative attention is constrained or limited, poor enforcement of guidelines, insufficient specialist staff and the liability pressure on clinicians were perceived barriers. To containing AMR in medical institutions, management of hospital infections, the public's knowledge of antibiotics' usage, routine education and multidisciplinary support would be facilitators. Practitioners from medical institutions were highly supportive for the NAP. Consideration of practitioners' perceived barriers and facilitators might enhance implementation of the NAP to contain antimicrobial resistance.

Solutions in search of a problem: Opening policy windows for Business Improvement Districts in the Nordic countries

Policy mobility literature invites us to consider the power-laden processes of how urban policies are exported, mimicked, and transformed in different urban contexts. However, recent critique has highlighted the need for a fuller understanding of urban policy context to understand where and when policies come to be implemented in new settings and how they are transformed. The purpose of this study is to explore understandings of urban policy context in a comparative study of policy mobility, and specifically relations between internationally packaged concepts, local pilot projects and national level actors. We develop a framework for understanding these relations in policy mobility based on case studies of BID policy development in Sweden and Denmark drawing on both Policy Mobility literature and a Multiple Streams Approach. The main finding is that local pilots play a key role in translating packaged policy concepts but also serve as ‘proof of concept’ for further institutionalization. The way these pilots are discursively situated in relation to ‘problems’ is therefore of central importance for further implementation. Furthermore, the study highlights the role of policy entrepreneurs that connect local pilots (and discursive problems) with national level actors, and political opportunities.

Low-carbon energy systems: seizing market-based business opportunities across borders

Asia has been experiencing much faster economic growth than the world average and has been consuming more energy and natural resources than our planet’s regenerative capacity can provide. With each passing day, Asia’s carbon emissions have been growing, as does its vulnerability to climate risks. The poor are the most vulnerable to these disruptions, lacking options to adapt to changing climatic conditions. The transition to a low-carbon green growth in almost all of emerging economies in the Asian region is underway. This transition has become unstoppable and irreversible. In this context, it is important to realize that the Coronavirus (COVID-19) pandemic has its own impact on the economies. Nevertheless, it has also created new once-in-a-generation opportunities for implementing hard policy reforms through economic recovery and stimulus packages. The need to accelerate the low-carbon transition as part of the pandemic recovery is unquestionable, but the question is how to do it in a cost-effective way. This research presents a broad diagnosis of new regional cooperation opportunities in areas essential to complete the transition to a low-carbon economy by 2030 and a net zero economy by 2050–2060. It highlights where regional cooperation and coordination can have the greatest impact. It points to a number of policy areas—trade, carbon taxation, carbon pricing, and innovation—where regional cooperation reduces the cost of implementing national actions and complements global pacts. This model also creates business opportunities for developing competitive green industries and low-carbon technologies across countries in the region.

Identify Factors in Increasing the Income of Micro, Small and Medium Enterprises (MSMEs) in Padang City

Micro, Small and Medium Enterprises (MSMEs) are the largest segment for national economic actors. MSME players can help the government reduce the number of unemployed people. So in Indonesia, micro, small and medium enterprises are often associated with government efforts to reduce unemployment, fight poverty, and equalize income. This research aims to identify the factors that influence the income of MSMEs in the city of Padang. The research design used in this research is causative research to identify factors that influence the income of micro, small and medium businesses in the city of Padang, where the research subjects used a purposive sampling approach with a margin of error of 5% so that the number of samples of micro and small business actors who have been and Having carried out digital promotions, the target was 385 respondents as measured by distributing a Likert scale questionnaire. Data analysis uses validity, reliability, classical assumption tests, multiple regression tests, F-tests and t-tests. The results of data analysis show that the role of government, capital, entrepreneurial competence and length of business have a significant effect, both partially and significantly, on MSME income.

Evaluating the National Action Plan (NAP) on antimicrobial resistance, and recommendations for the next 5-year NAP: a roundtable discussion

Abstract The UK’s current 5-year National Action Plan (NAP) on tackling antimicrobial resistance (AMR), which runs from 2019 to 2024, is coming to an end. As such, the next 5-year NAP is currently under development, and progress made towards the UK’s commitments on AMR is being analysed. This analysis has involved the publication of an addendum to the current NAP, which includes some new and revised commitments. Applied Microbiology International (AMI) held a roundtable discussion in November 2022, inviting UK experts from across the human and animal sectors to discuss their thoughts on progress to date, as well as any recommendations and key considerations they thought should be taken forward. Overall, it was agreed that there is a major disparity between the increasing ambitions of the NAP, and the reducing financial support for achieving said ambitions. The gap between evidence generation and implementing recommendations into real-world settings also presents a key challenge to overcome, if the NAPs commitments are to be achieved. A lack of communication and funding appear to underpin many of the barriers that prevent the successful delivery of current NAP commitments and are therefore highlighted as key areas of concern for policymakers to consider when looking to tackle AMR. The focus should be on successfully implementing and delivering the current NAP commitments ahead of identifying future ambitions.

Following Kant's footsteps in Spain

In 1876, Hans Vaihinger, a German philosopher and professor at the University of Halle, founded the journal Kant-Studien. One of the main objectives of this project was to investigate the impact of Kantian philosophy outside Germany. The first correspondent for the journal was a Polish philosopher and national activist – Wincenty Lutosławski. His report on the study of the Spanish reception of Kant was published in the first issue of the journal Kant-Studien in 1897 under the title “Kant in Spanien.” In my article I present the history of the emergence of Lutosławski’s report and I describe the Polish encounters with Spanish culture and philosophy in the 19th century.

Ukrainians as “Aliens” (Inorodtsy): Governmental Regulation of Ukrainian Cultural Associations, 1905–17

AbstractThis article presents a history of the imperial government’s regulation of Ukrainian cultural associations, which appeared around the Romanov Empire in the aftermath of the 1905 Revolution. It centers on the prehistory, drafting, and implementation of Circular No. 2 (1910), issued by the Ministry of Internal Affairs and signed by Petr Stolypin on January 20, 1910, which labeled Ukrainian associations “alien.” By studying the document in a wider chronological and geographical context than in previous scholarship, I argue that even though the circular aimed at curbing any non‐Russian nationalist activity irrespective of national group, its more specific goal was to avert a break‐up of the tripartite Russian nation by preventing the inhabitants of the southwestern provinces from becoming Ukrainians. Therefore, the circular’s characterization of Ukrainians as “aliens” was neither an accident nor a bureaucratic mistake, as is suggested in the historiography, but should be considered as a manifestation of the embrace of Russian nationalism by the highest officials of the empire. Additionally, the haphazard implementation of the circular further revealed the multilayered nature of the late imperial bureaucracy, as well as the empire’s inconsistent nationalization on the eve of the First World War.