The rapid advancement of technology has transformed traditional classroom settings into complex digital learning environments, emphasizing the need for effective Human-Computer Interaction (HCI) strategies to enhance online learning experiences. This research explores the intersection of HCI and digital learning, focusing on how HCI strategies can improve user engagement, comprehension, and learning outcomes. Through a review of existing literature, this study identifies common challenges faced by learners and educators, such as usability issues, technical difficulties, and inadequate localization. It also highlights effective HCI strategies, including user- centered design, interactive multimedia features, and feedback mechanisms, which are crucial for creating engaging and personalized learning experiences. Findings indicate that personalized learning systems and interactive content significantly enhance performance and achievement by addressing individual learning needs and improving content retention. Best practices derived from user feedback suggest adopting a user-centered design approach, integrating interactive elements, focusing on usability, and continuously updating learning tools. This research underscores the importance of aligning HCI principles with educational technology to foster a more effective and inclusive digital learning environment. Keywords - Human-Computer Interaction (HCI), Digital Learning Environments, User Experience (UX),Interactive Design, Personalized Learning, Educational Technology.