Multidisciplinary Research Methods Research Articles

Chemical genetics analysis suggests the involvement of Aurora kinase and MAPKs in aluminum-induced malate secretion in Arabidopsis.

Chemical genetics is a multidisciplinary research method. In this study, it is used to screen compounds that promote aluminum-induced malate secretion in Arabidopsis thaliana. Inhibition of p38 mitogen-activated protein kinase (p38 MAPK; LY2228820) significantly increased the transcription of Arabidopsis thaliana aluminum-activated malate transporter 1 (AtALMT1) and sensitive to proton rhizotoxicity 1 (STOP1)-regulated genes, multidrug and toxic compound extrusion and aluminum sensitive 3, but not AtSTOP1 and the Al-biomarker genes At3g28510, At5g13320, suggesting that LY2228820 increased the early expression of STOP1-regulated genes without affecting AtSTOP1 expression. Inhibition of p38 MAPK (LY2228820) and Aurora A (MLN8237) increased aluminum-activated malate transport via AtALMT1, suggesting that both MLN8237 and LY2228820 interfere with AtALMT1 activity. An increase in root elongation was also observed in Arabidopsis after applying compounds LY2228820 and MLN8237. Thus, both LY2228820 and MLN8237 may play important roles in alleviating the inhibitory effects of aluminum on roots.

How to measure the impact of landsenses ecology on sustainable development? A review of people-oriented emerging approaches

At present, the research of sustainable development is developing from a single local problem to a multi-scale, transdisciplinary and comprehensive study. The evaluation and monitoring of its progress need to adopt multi-disciplinary research methods and multi-dimensional, multi-scale identification mechanism. Landsenses ecology is an emerging scientific system that uses the basic principles of ecology to study the sustainable development of land-use planning, construction, and management from the aspects of natural elements, physical senses, psychological perceptions, social economy, process and risk. It provides an effective way for the multi-disciplinary integration research of the relationship between human and ecosystem, and provides an important method and theory for the sustainable transformation research of environmental system and social–economic system, and plays an important role in guiding and realizing the beneficial impact of human on natural ecosystem. This study describes 57 articles published in peer-reviewed journals between 2016 and 2024, using qualitative content analysis, and discusses the impact of landsenses ecology on the way sustainable development is perceived and practiced. The results suggest that the role of landsenses ecology in the creation of sustainable vision resonance and behavior is crucial to the study of sustainable transformation and will help to explore effective strategies for using intrinsic sustainable transformation as a deep leverage point.

The Influence of Ecological Identity on the Cultural Significance of Traditional Urban Public Spaces in Cultural Landscapes

Traditional urban public spaces are highly significant because they retain identities, histories, and memories of thecommunity in any cultural landscape. These spaces have existed since the prehistoric era and are an important part of alandscape's unique identity. These spaces are also a part of larger ecological settings, where ecological features have animpact on the design, purpose, and cultural significance. Therefore, This paper identifies specific indicators of ecologicalidentity through the application of case study analysis and multidisciplinary research methods and explores the influence ofecological features in and around traditional public spaces on their cultural significance within a cultural landscape. Thefindings reveal that the natural environment and traditional public spaces are intricately entwined with human culture inthe chosen study area and emphasise how important it is to comprehend the interactions between ecological and culturalfactors to conserve such spaces while promoting sustainable urban development.

Research on the Interface Design of Persimmon Dyeing Culture based on Situation Construction

China's persimmon dyeing culture has a profound heritage and is rich in national characteristics. However, with the departure of the production artists, the persimmon dyeing culture is facing the severe challenge of rapid extinction. In order to continue to promote Chinese persimmon dyeing culture and improve the public's awareness of persimmon dyeing, by analyzing the historical background, artistic value, and social significance of persimmon dyeing culture, and building a theory based on the situation, a small program of persimmon dyeing culture was constructed to spread Chinese persimmon dyeing, to enhancing user experience and cultural identity. The research adopted a multi-disciplinary research method, which was user-centered and combined with historical document research, sociology, art, and information technology to comprehensively analyze the persimmon dyeing process. User testing and feedback show that the small program is highly interactive, has high user participation and can provide users with an immersive experience. This research not only has important practical value for the inheritance of persimmon dyeing culture, but also provides new perspectives and methods for the digital dissemination of traditional culture.

Beyond Westphalia-The Difficulties of the Three Principles of Realism

International actors are fundamental units of research in the field of international relations, with state actors being the primary focus. The political relationships between countries serve as the basis for current mainstream research in international relations theory. However, the author believes that with the evolution of the international system and the increasing complexity of the international community, the traditional Westphalian system and its derivative concept of absolute sovereignty have become outdated. This limits the effectiveness of the current paradigm used to describe objective reality and its ability to guide practical applications. As a result, it is necessary to redefine these propositions. In this paper, the author will use literature investigation and historical analysis methods to deconstruct the three mainstream views of the national center, rational countries, and single country perspectives. This will demonstrate that a variety of international actors and power centers have emerged in the field of international relations and are playing increasingly important roles. This highlights the need to move beyond the limitations of a single nation system towards a more nuanced understanding of international relations. Through a multi-center perspective and utilizing multidisciplinary research methods, including techniques from quantum mechanics, the author will work towards developing a more accurate theory based on the reality of the international relations system.

Reimagining Human Rights: Harnessing the Power of Law for Global Health and Sustainable Development Goals

The concept of human rights has long been an integral part of global discourse, championed as a fundamental pillar of social justice and equity. In recent decades, the intersection of human rights, global health, and sustainable development has emerged as a critical area of concern and opportunity. This research paper delves into the dynamic intersection of human rights, global health, and sustainable development, with a particular focus on Sustainable Development Goal 3 (SDG 3) - Good Health and Well-Being. In the context of our rapidly changing world, by applying a multidisciplinary research method, this paper explores the evolving landscape of human rights preservation and the challenges posed by emerging global governance issues. By examining the role of law in promoting and safeguarding human rights within the framework of SDG 3, it offers a comprehensive analysis of the evolving global governance challenge in the quest for a healthier and more sustainable world.

Emoticons Unveiled: A Multifaceted Analysis of Their Linguistic Impact

This study aims to thoroughly investigate the linguistic impact of emojis and emoticons in modern written communication. This work attempts to shed light on these digital symbols’ linguistic structure, social implications, and evolution through a multidisciplinary research method. A mixed-methods approach was used in the research, integrating interdisciplinary viewpoints with quantitative and qualitative analyses. A vast amount of data was gathered from various digital communication channels, such as email exchanges, messaging apps, and social media. A sizable collection of text messages with emojis and emoticons was assembled. Emotional cons and emojis were categorized using linguistic analysis, breaking down their structure into visual components and repeating patterns. Their grammatical and syntactic effects on written language were also evaluated in this investigation. The findings indicate that using emojis in writing positively correlates with emotional expressiveness. This implies that when people wish to express emotions and subtlety in their messages, they typically utilize more emoticons. They enhance digital etiquette, reduce misunderstandings, improve emotional connection, and foster cross-cultural understanding. Emoticons are a global visual language that helps people communicate, create empathy, and navigate digital communication.

Opioid Use Disorder and Overdose in the First Year Postpartum: A Rapid Scoping Review and Implications for Future Research.

Opioid overdose is a leading cause of maternal mortality, yet limited attention has been given to the consequences of opioid use disorder (OUD) in the year following delivery when most drug-related deaths occur. This article provides an overview of the literature on OUD and overdose in the first year postpartum and provides recommendations to advance maternal opioid research. A rapid scoping review of peer-reviewed research (2010-2021) on OUD and overdose in the year following delivery was conducted in PubMed, PsycINFO, and Web of Science databases. This article discusses existing research, remaining knowledge gaps, and methodological considerations needed. Seven studies were included. Medication for OUD (MOUD) was the only identified factor associated with a reduction in overdose rates. Key literature gaps include the role of mental health disorders and co-occurring substance use, as well as interpersonal, social, and environmental contexts that may contribute to postpartum opioid problems and overdose. There remains a limited understanding of why women in the first year postpartum are particularly vulnerable to opioid overdose. Recommendations include: (1) identifying subgroups of women with OUD at highest risk for postpartum overdose, (2) assessing opioid use, overdose, and risks throughout the first year postpartum, (3) evaluating the effect of co-occurring physical and mental health conditions and substance use disorders, (4) investigating the social and contextual determinants of opioid use and overdose after delivery, (5) increasing MOUD retention and treatment engagement postpartum, and (6) utilizing rigorous and multidisciplinary research methods to understand and prevent postpartum overdose.

How to Remove the Stigma? Effects of Protective Policy for Transgender: Based on Transgender-Inclusive Policies in Schools of California

With transgender gaining more visibility among the public, transgender students still experience stigmatization on campus. Based on this, the paper explores policy initiatives taken to promote greater trans-inclusive climates to remove stigma and policy limitations in schools in California. Firstly, transgender stigma is presented in three fields related to discourse, identity, and value. Employing policy analysis based on one case, which is a multidisciplinary research method that seeks to generate, assess, and disseminate policy-relevant knowledge. This paper also reviews the current policies of transgender protection in California, further examining the effects of the transgender-inclusive policies in one specific area and the limitations. Finally, this paper ends with some recommendations for what kind of revision or reform is anticipated to remove transgender stigmatization. This research not only stimulates further discussion of the transgender youth which is a relatively hidden group but also serves as the source in favor of changing policy to improve access to high-quality care and the advancement of the rights of transgender individuals.

A Hybrid Approach for Identification of Deficiencies in Enterprise Internal Control

Enterprise management and internal control are used to prevent and control risks and promote enterprises to achieve development strategy. This paper adopts comprehensive multidisciplinary research method to study the basic theory of prediction of major defects in enterprise internal control. Firstly, this paper proposes the prediction index system and sample selection standard of internal control major defects. Totally, 630 listed company and 12 indicators are collected and then use the random forest classification method based on principal component analysis. The parameters of random forest are optimized by genetic algorithm. Finally, the prediction model of major internal control defects of listed companies is established. The experimental results show that the average score of PCA-RF model in TPR value reaches 85%, which is nearly 20% higher than the 65% of RF model, proving that the PCA and GA can significantly improve the classification accuracy of ST Company and has important practical significance. Therefore, the proposed method system can reasonably solve the prediction problem of major defects in internal control.

Study on the Application of Chinese Traditional Visual Elements in Visual Communication Design

This study analyzed the data collected from field research and SD questionnaires on the application of traditional elements in Aba Prefecture. This study adopted the multidisciplinary research method integrating linguistics, architecture, art, and statistics of science and technology to discuss the related issues of the cultural industry park, and analyze the expression of traditional art elements in the visual communication of the cultural industry park. First, based on the photographs taken, we analyzed the layout of typical scenes of traditional element applications on the plane, including the analysis of traditional element types, colors, and materials. Second, the SD questionnaire results are displayed and analyzed. From the comprehensive scores of the respondents, we learned that the application of traditional elements has different effects on the architectural landscape. The main results show that (1) the public has a positive attitude toward the expression of traditional culture in the planning and construction of the park. Scenes rich in traditional elements play a positive role in the transmission of traditional culture and the creation of a traditional atmosphere; (2) showing traditional architectural styles and landscape layouts in a reproducible way can more intuitively set off the traditional cultural atmosphere; (3) the texture of the stone wall has certain rules and principles. The arrangement and combination of stones are a plane composition, and the visual characteristics brought by the wall can be specifically analyzed according to the elements of the plane composition. The stone masonry wall is analyzed according to the elements of plane composition, which can be divided into visual elements and relational elements. The visual elements are divided into the size, shape, color, and texture of the image, and the relational elements refer to the relationship between position and arrangement, including orientation, location, and center of gravity.

The Current State and Development of Research on China-South Korea Cooperation Under the 30<SUP>th</SUP> Anniversary of the Establishment of China-South Korea Diplomatic Relations - Based on the Visual Analysis of CSSCI Journal Documents-

The year 2022 marks the 30th anniversary of 30th Anniversary of the Establishment of China-South Korea Diplomatic Relations . Over the past three decades, China-South Korea relations have witnessed rapid development and fruitful exchanges and cooperation in various fields, which have not only brought tangible benefits to both sides but also made positive contributions to regional and world peace and stability. Now, standing at a new starting point, how to push China-South Korea relations to a new level has become a topic of close attention on both sides. Therefore, on the basis of nearly 30 years of research, scholars of China and South Korea put forward a new path and new model for the sustained and stable development of China-South Korea relations and cooperation.<BR> In this paper, 191 china-South Korea cooperative research papers published on CSSCI journals in the Database of China National Knowledge Infrastructure (CNKI) were selected as samples, and literature measurement and content analysiswere used for research and analysis. Based on the preliminary outline of the annual distribution of literature samples, the distribution of major journals, the distribution of authors and their institutions, the paper uses CiteSpace software to sort out the hot topics and the evolution trend of China-South Korea cooperation research. The analysis results show that, on the whole, there are many researches on China-South Korea relations, China-South Korea FTA and The Korean Peninsula issue in Chinese academic circles, with increasing academic attention. However, the research strength is relatively scattered, and a mature and stable cooperation network and academic community has not yet been formed. The researches mainly focus on economic cooperation, and lack cooperation in other fields, as well as cooperation risks and coping strategies. In other words, complex risks and systemic risks in international cooperation are not paid enough attention, which also restricts the further research. The majority of research methods are qualitative research, and the big data analysis with integration of multidisciplinary research methods still needs to be improved.

New mode of data-intelligence fusion research on clinical &amp;ldquo;toxic&amp;rdquo; Chinese medicines: The proposal of evidence-based Chinese medicine toxicology

<p indent="0mm">The safety issues of Chinese medicine have always been regarded as a vital issue, which has been restricting the development of the Chinese medicine industry and has long had implications for public health. This is especially true for the clinical drug application of “toxic” Chinese medicines which are generally acknowledged as being a fairly complicated and hazard-prone area. These distinguishing features of “toxic” Chinese medicines noted above have limited the safe and rational clinical drug application of traditional Chinese medicine. However, previous research approaches have been subject to many limitations such as insufficient integration of basic research with clinical research, the lack of leadership and guidance for the system view and overall view. These trends of current academic studies show that there are plenty of serious difficulties in transforming the research data into effective evidence, to support the present demand for the rational clinical drug application for “toxic” Chinese medicines. In the wake of the inclusion of data as one of the elements in the scope of market-oriented reform, the scientific and technological innovation in the area of big data has occasioned the birth of data science. This will generate new opportunities for the development of the traditional Chinese medicine industry. Our team is in the early stages of developing a methodological system for traditional Chinese medicine evidence-based research which is based on the “four syndromes”, with characteristics of “syndrome production-syndrome differentiation-syndrome and application-syndrome verification”. This paper is guided by traditional Chinese medicine theory, drawing on the experience from the concept of evidence-based medicine, and introducing multidisciplinary and interdisciplinary technologies, such as digital twins, and artificial intelligence. Based on these parameters, our team further proposes the research concept of evidence-based Chinese medicine toxicology, and plans to build up one new mode of data-intelligence fusion research on clinical “toxic” Chinese medicines. To be specific, multi-disciplinary research methods will be applied, such as conventional toxicology, translational toxicology, toxicological genomics and clinical medicine. The research data of “toxic” Chinese medicines will subsequently be analyzed, which could include studies on clinical characteristics, toxic substance basis, toxicokinetics, toxic molecular mechanisms and toxicity-effect conversion regulation. Further, the integrative transformation between data and evidence will be carried out with the help of artificial intelligence, a disease-syndrome digital twin modeling system and other evidence-based toxicological technologies. Thus, the evaluation and prediction method using multiple and integrated evidence for “toxic” Chinese medicines will be set up, and then, the research method and technical path of evidence-based Chinese medicine toxicology will be refined, by being built around the core of data-intelligence fusion. In conclusion, this article designates data as the foundation and intelligence as the navigation, to provide new ideas and a reference base for the safety research into Chinese medicine.

Interaction Mechanism between Formation Process of Bank Collapse Disaster Chain and Territorial Space Utilization of Large Reservoirs

Number of reservoirs in China ranks the first in the world. Due to the complex geology, and superimposing rainfall and reservoir water fluctuation, the bank collapse chain is prone to disasters. The Yangtze River Reservoir is key geological disaster prevention area. Studying the process of reservoir disaster is significant because of the limited territorial space utilization. Scientific and technological issues, i.e., the mechanism of bank collapse disaster chain of large reservoirs, the interaction mechanism of bank collapse disaster chain and territorial space utilization, the early identification, monitoring technology and ecological prevention and control technology system of disaster chain, and the territorial space geological safety and control technology system are focused. We consider the material transformation, energy transfer and information transmission in disaster chain; adopt the survey, Space-Air-Ground integrated monitoring, theoretical analysis, numerical simulation and the multidisciplinary research methods; reveal the chain source development, evolution process of secondary and derivative disasters; explore the interaction mechanism of disaster chain and territorial space utilization; construct the system of early identification, monitoring, early warning, control and ecological preven-tion to achieve Emission Peak and Carbon Neutrality; provide theoretical and technical support for the territorial space geological safety, regulation and utilization of large reservoirs.

Supply-side Reform of University Ideological and Political Education Based on Big Data

With the development of science and technology, people use more and more data, so big data plays a key role in the problem of excessive capacity. This article mainly introduces the collaborative innovation research on the supply-side reform of ideological and political education (IPE) of university campus culture based on big data, and intends to provide some ideas and directions for the collaborative innovation research on the supply-side reform of university IPE. This paper proposes a collaborative innovation research method based on big data for the supply-side reform of IPE on university campus culture, including document retrieval method, interview method, questionnaire survey method, multidisciplinary research methods and big data-based research methods. The experimental results of this article show that the average value of the correlation coefficient α of the questionnaire reliability is 0.91, indicating that the reliability of the questionnaire in this article is relatively high, and it can provide relevant references for this research.

Land Use and Ecological Civilization: A Collection of Empirical Studies

The goal of ecological civilization construction is to realize the harmonious coexistence of human and nature. Land is the spatial carrier of ecological civilization construction. Land use types or behaviors reflect the level of intensive use of land resources, leading to different ecological environmental effects, thereby affecting the level of regional ecological civilization construction. This issue, “Land Use and Ecological Civilization”, discusses the theory and method of land use management in the view of ecological civilization from the aspects of land use efficiency, land use change, land multi-functional trade-off, land ecosystem service and land ecological risk by selecting 14 representative papers, providing practical reference for the formation of the land use mode and behavioral system of ecological civilization. With abundant research levels, this issue covers varied research scales such as village, county and province, various landform types such as plain and hill, and typical land use areas at home and abroad such as East China, Central China, Northwest China, Yangtze River Economic Belt and Japan. Being frontier and practical, the multidisciplinary research methods in this issue include literature research method, fractal theory, qualitative comparative analysis, VAR model, and econometrics, among others. Focusing on the prominent problems in the process of land use, this issue deeply discusses the hot topics such as land ecological efficiency, spatial behavior characteristics, land use structure optimization and ecological risk assessment. This issue not only reviews the current literature on urgent land use issues such as arable land abandonment and land use risk, but also tries to conduct trade-off and synergy analysis on the varied functions of the rural landscape and ecosystem, thus providing a theoretical and empirical basis for solving land use problems from the perspective of ecological civilization. This issue reflects the realistic urgency of guiding land use with the concept of ecological civilization, and provides theoretical guidance and technical support from the aspects of methods and research framework. Finally, this issue proposes five hot topics in the field of land use research from the perspective of ecological civilization in the future, namely, ecological management of land use structure, ecological evolution mechanism of land use process, land ecological use mode, early warning and regulation of land ecological security pattern, ecological management and control of land use behavior.

Multidisciplinary research method for designing and selection of bio-inspired profiles in the conceptual designing stage

A multidisciplinary research method was employed with the intention to create a series of bio-inspired flattened airfoils, observe their aerodynamic characteristics, and analyse their applicability to small devices or to designs of high-speed trains, within the shortest period in the conceptual stage. A research specimen of a kingfisher, selected for biomimicry, was examined with the following methods: visual inspection, analysis of photographs, manufacturing quality control measurement with a 3D laser scanner, and microscopy. A basic multi-arc-line profile, re-engineered from the overlapped specimen shape data and based on the observations, was used for designing a series of seven derived airfoils. The aerodynamic characteristics of the bio-inspired airfoils were obtained with the panel methods at low and moderate subsonic speeds, while the small transonic difference method was used in the high-subsonic speed range. Basic and ellipse-like airfoils produce higher total drag at low and moderate velocities and higher forebody drag in the high-subsonic range when compared to derived and parabola-like airfoils. The obtained critical Mach numbers are in the range from 0.76 to 0.78, where three bionic airfoils show values equal to or smaller than the values of ellipse- and parabola-like airfoils. The profile with the shortest bio-inspired relative chord has a higher critical Mach number value than the parabola-like profile. The sonic lines above these profiles appear at close positions. The applied set of examination methods of the bio-inspired design is not time consuming and produces sufficiently good results in the conceptual stage. Therefore, a further development of unique and adjusted numerical methods and codes at pre-computational fluid dynamics run is encouraged, together with shape parameterization.

Introduction: Studying Under-Floor Church Burials in Finland\u2013\u2013Challenges in Stewarding the Past for the Future

Two ongoing projects at the University of Oulu, Finland, are studying burials situated below the floorboards of Finnish churches. The projects examine mortality and materiality in Finland using an exceptionally well-preserved assemblage of mummified human remains. Multidisciplinary research methods, including CT scanning, μCT scanning, sampling for DNA and isotope analysis, and insect and plant samples, are providing multifaceted information concerning past societies. The samples provide rich insight into the material dimensions of mortality in northern Europe in the 18th and 19th centuries. Since the studied material is located under the floors of church buildings that are still in use by congregations, obtaining permits for research and sampling has required managing relationships with separate parishes. This article outlines the projects and examines the ethical and legal dimensions of research on human remains conducted in partnership with individual parishes.

A brief review on studies of the Chinese Red Army medical aid

The Chinese Red Army medical aid not only has collected and collated existing data but also has studied related contents.With regard to the collection of data and materials, there were both medical-health thematic data and medical-health data covered by the comprehensive data, reprinted and translated of documentary data.With respect to medical aid research, there were both comprehensive and thematic studies. Among thematic studies, included medical institutions, health teams, methodology, role of health work, medical aid with traditional Chinese Medicine, and the research of Red Army medical staff.Looking forward to the future research, we should focus on literature mining and data expansion, innovation of research perspective, integrated application of multidisciplinary research methods, diversity of research subjects and the "normalization" of research results.

Structural Genocide and Institutionalized Racism in Canada: The Department of Indian Affairs and Framing of Indigenous Peoples

This review problematizes the health and socio-economic disparity between Indigenous and non-Indigenous communities, which I argue is due to the role of the Canadian government. Specifically, I analyse the continuous process of Indigenous administrative subjugation under Canadian rule to uncover the intrinsic racial predilections of Canadian government policy toward First Nations peoples in Canada’s Prairie West provinces through the application of diagnostic frame analysis as a multidisciplinary research method to analyse how people understand situations and activities. My research results reveal the racialized marginalization of First Nation peoples through the administrative regimes in Canada as a continuous contemporary process established in the late nineteenth and twentieth century. In exposing the structural discrimination of First Nations peoples, my research introduces the reader to the concept of political master narratives, or ‘imaginaries’. These imaginaries foster the health and socio-economic disparities between Indigenous and non-Indigenous groups in Canadian society. The critical analysis of these historically structural government instituted imaginaries and the indirect, exponentially higher chances of tuberculosis and related diseases and deaths among Indigenous peoples’ challenge conclusions of the Truth and Reconciliation Commission (TRC) on cultural genocide. This study proposes structural genocide as a more accurate and inclusive term for the continuous institutional marginalization of not only Indigenous peoples as seen in this case study of the Department of Indian Affairs (DIA) but for all Indigenous peoples in Canada.