Multicomponent Composition Research Articles (Page 1)

Single-cell omics reveal the mechanisms of traditional Chinese medicines.

The advancement of high-density integrated electronics urgently demands materials that integrate efficient thermal management and microwave absorption. However, conventional design strategies that often rely on materials with multi-component composites face a trade-off between these properties, and a lack of microwave absorption effectiveness study in the polymer matrix. Herein, a fluorine-mediated carbon doping in boron nitride (C-F-BN) is designed to achieve atomic-level interface engineering. Fluoride induces the formation of polarized C─F bonds and promotes ordered sp2-carbon incorporation, which well preserves the BN lattice integrity while establishing strong polarization sites. The resulting C-F-BN shows exceptional microwave absorption with a reflection loss of -43dB at 2mm thickness, compared to that of only carbon doping in BN, achieving an effective absorption bandwidth of 3.52GHz and a remarkable absorption efficiency index of 35 dB· GHzmm-1. The maintained BN crystallinity, ordered sp2-carbon conversion, and enhanced interfacial compatibility between C-F-BN and polyvinyl alcohol (PVA) enable PVA/C-F-BN composites to attain higher through-plane thermal conductivity (0.2599 W·m-1·K-1) at a lower filler loading (5 wt.%). Moreover, the composite exhibits a broader absorption bandwidth of 3.84GHz with a reflection loss of -32dB. The design concept offers a feasible route to multifunctional materials for advanced electronic packaging.

Subject matter: models for the formation of the logistics infrastructure for complex equipment recycling, taking into account the two-stage processing system and the multicomponent composition of secondary raw materials. This study aims to develop a model for the formation of a logistics infrastructure for complex equipment recycling enterprises, the implementation of which will reduce transportation costs of secondary raw materials and infrastructure development expenses. Objectives: to investigate the current state and challenges of complex equipment recycling in Ukraine and abroad; to identify the characteristics of logistics processes in complex equipment recycling; to develop a model for the formation of recycling logistics infrastructure for complex equipment. The following methods were used during the research: mathematical modeling, location-allocation methods, and systems approach. Research results: the current state and challenges of complex equipment recycling have been analyzed, including infrastructure deficiencies, a low level of sorting, and uneven distribution of processing facilities; approaches to solving the facility location problem for recycling infrastructure have been reviewed; a two-level structure of the complex equipment recycling system has been developed, consisting of a network of local collection and sorting centers and processing enterprises; a mathematical model for forming the logistics infrastructure has been developed, considering production capacities, transportation costs and the multicomponent nature of resources. The conclusions state that the proposed optimization model for the logistics infrastructure of complex equipment recycling considers a two-stage processing sequence, from collection and sorting to final recycling. The model integrates economic, spatial, and technological factors, enabling the minimization of total transportation and infrastructure development costs. The application of the proposed model ensures effective planning of the recycling network, taking into account processing capacities, logistical routes, and the volume of different types of secondary raw materials.

SUMMARY. Vision is essential for human activity, yet over 2.2 billion people worldwide face visual impairments, many of which are preventable. Digital screen exposure further exacerbates eye health issues. While treatment options exist, their cost makes prevention increasingly relevant. The use of plant-based dietary supplements offers a viable preventive strategy. Analyzing their assortment, composition, and dosage forms is key to improving quality control and guiding the development of effective products for visual function support. The aim – to investigate the pharmaceutical assortment of dietary supplements for the normalization of visual function. Material and Methods. The objects of the study were the directory of Compendium online and online resources such as Tabletki.ua and Apteki.ua. The study employed marketing analysis, graphical representation, logical generalization, and mathematical-statistical methods. Results. As of April 2025, the pharmaceutical assortment comprised 104 dietary supplements for the normalization of visual function. The analysis of the assortment revealed a predominance of domestically produced dietary supplements, accounting for 55.77 %. The leaders among them were Beauty and Health, LLC (10.34 %) and Elit-Pharm, LLC (8.61 %). Imported dietary supplements originated from 16 countries, with the highest shares coming from Germany and the United States (19.57 % each). The majority of dietary supplements had a multi-component composition (86.54 %). The most common dosage forms were capsules and tablets. Conclusions. The domestic pharmaceutical market of dietary supplements for the normalization of visual function has been analyzed. The results indicate a predominance of domestically produced products, a multi-component structure of the assortment, and a variety of dosage forms, highlighting the high potential for further research and development based on plant-derived raw materials.

By integrating cathodic arc evaporation (CAE) with magnetron sputtering (MS) or high-power impulse magnetron sputtering (HiPIMS), hard coatings with diverse multicomponent compositions can be fabricated. Depending on the deposition conditions, the coatings with nano-composite or nano-multilayered microstructures are produced. During the mixing deposition conditions, nano-composite coatings are fabricated, which can be tailored to possess combining properties of super hardness, low friction coefficient, and excellent thermal/chemical stability. For the deposition with larger rotating periods, layer-by-layer deposition was observed. By the nano-multilayered coating design, superior mechanical properties (hardness ≥ 35 GPa), modulated residual stresses, and enhanced high-temperature properties can be obtained. In addition, lubricious elements, low friction (friction coefficient < 0.4), and low wear (<10−5 mm3/N∙m) both at ambient temperature and high temperature can be realized. Among these coatings, some have been specifically designed to achieve outstanding cutting performance in high-speed cutting applications. Several nitride and oxide hard coatings, such as AlTiN, TiAlN/TiSiN, AlCrN/Cu, and AlCrO, were deposited using a hybrid industrial physical vapor deposition (PVD) coating system. The microstructure, mechanical properties, and cutting performance of these coatings will be discussed.

The limitations imposed by the inherent complexity of multi-component composition ratios in biological polymer-stabilized soils have hindered rapid and accurate performance prediction. To enhance the predictive accuracy for biopolymer-fiber-stabilized soils, an optimized GA-driven backpropagation (BP) neural network was developed. Three key factors influencing mechanical strength (guar gum (GG), xanthan gum (XG), and polybutylene succinate (PBS)) were identified. The global optimization capability of GA was utilized to construct an integrated GA-BP model, with these factors serving as inputs and 7d compressive strength as the output. Support vector machine (SVM) was also incorporated to provide a benchmark comparison of predictive performance. Validation was performed using 80% of the dataset, with the remaining 20% used for testing. The optimal biopolymer dosage was found to be within the range of 0.5% to 1.0%, and the maximum 7d compressive strength achieved was 466.67 kPa at the 0.5% XG-0.5% GG combination, representing a 273% increase over untreated soil. The GA-BP model demonstrated superior performance in terms of prediction accuracy and stability, as indicated by an R2 of 0.887-significantly higher than those of the BP (0.714) and SVM (0.554) models. The mean squared error was substantially reduced to 1413, compared to 2130 and 3113 for BP and SVM, respectively. Although MAPE approached those of the GA-BP, the overall predictive efficacy of SVM was found to be inferior. A reliable and robust methodology for forecasting the mechanical behavior of stabilized soils has thus been provided by this model, supporting advanced applications within geotechnical engineering.

This work aimed to advance the knowledge in the field of eco-friendly dielectrics with applicative relevance for future energy-related technologies. New multicomponent composites were prepared by using a cellulose ether/citric acid mixture as the matrix, which was gradually filled with strontium titanate nanoparticles (5–20 wt%). In this case, citric acid can act as a crosslinking agent for the polymer but also can react differently with the other counterparts from the composite as a function of the solvent used (H2O and H2O2). This led to considerable differences in the morphological, thermal, optical, and electrical characteristics due to distinct solvent-driven interactions, as revealed by the infrared spectroscopy investigation. Hence, in contrast to H2O, the oxidizing activity of H2O2 led to changes in the surface morphology, a greater transparency, a greater yellowness, an enhanced refractive index, and higher permittivity. These data provide new pathways to advance the optical and dielectric behavior of eco-compatible materials for energy devices by the careful selection of the composite’s components and the modulation of the molecular interactions via solvent features.

Al-Mg-Si (6XXX) series aluminum alloys are widely applied in aerospace and transportation industries. However, exploring how varying compositions affect alloy properties and deformation mechanisms is often time-consuming and labor-intensive due to the complexity of the multicomponent composition space and the diversity of processing and heat treatments. This study, inspired by the Materials Genome Initiative, employs high-throughput experimentation-specifically the kinetic diffusion multiple (KDM) method-to systematically investigate how the pop-in effect, indentation size effect (ISE), and creep behavior vary with the composition of Al-Mg-Si alloys at room temperature. To this end, a 6016/Al-3Si/Al-1.2Mg/Al KDM material was designed and fabricated. After diffusion annealing at 530 °C for 72 h, two junction areas were formed with compositional and microstructural gradients extending over more than one thousand micrometers. Subsequent solution treatment (530 °C for 30 min) and artificial aging (185 °C for 20 min) were applied to simulate industrial processing conditions. Comprehensive characterization using electron probe microanalysis (EPMA), nanoindentation with continuous stiffness measurement (CSM), and nanoindentation creep tests across these gradient regions revealed key insights. The results show that increasing Mg and Si content progressively suppresses the pop-in effect. When the alloy composition exceeds 1.0 wt.%, the pop-in events are nearly eliminated due to strong interactions between solute atoms and mobile dislocations. In addition, adjustments in the ISE enabled rapid evaluation of the strengthening contributions from Mg and Si in the microscale compositional array, demonstrating that the optimum strengthening occurs when the Mg-to-Si atomic ratio is approximately 1 under a fixed total alloy content. Furthermore, analysis of the creep stress exponent and activation volume indicated that dislocation motion is the dominant creep mechanism. Overall, this enhanced KDM method proves to be an effective conceptual tool for accelerating the study of composition-deformation relationships in Al-Mg-Si alloys.

This review provides a comprehensive and critical analysis of the recent progress (2021–2025) in the application of molybdenum disulphide (MoS2) and molybdenum diselenide (MoSe2) for renewable energy. We focus on three pivotal areas: electro catalytic hydrogen evolution (HER), photovoltaics (PV), and energy storage. We dissect the key strategies for material enhancement, including Nano structuring, phase and defect engineering, and the design of advanced heterostructures. A central theme is the critical trade-off between enhancing performance metrics—such as catalytic activity, power conversion efficiency, and specific capacity—and ensuring long-term operational stability and scalability. By synthesizing findings from recent literature, we highlight a paradigm shift from single-material systems to complex, multi-component composites where synergistic effects are paramount. We critically evaluate the role of computational screening in accelerating material discovery and identify persistent challenges, including interfacial instability, intrinsic conductivity limitations, and the gap between lab-scale demonstration and industrial viability. The review concludes by outlining key knowledge gaps and proposing high-priority research directions aimed at unlocking the full potential of these versatile 2D materials for a sustainable energy future.

Multicomponent aluminum composites Al – Cr – Zr, Al – Cr – Zr – Co – Ti – Cu with small additions of nanoparticles of refractory compounds SiC or MgAl2O4: thermochemistry, structure and properties

Introduction. The issue of the sufficiency of natural resources of medicinal plants is currently becoming more and more acute. This is the reason for investigating the possibility of using invasive plants as sources of biologically active substances. Xanthium strumarium L. is a plant of the Asteraceae family, weed plant that is widespread almost all over the globe and has a multicomponent composition. Its use in the treatment of various pathologies is actively covered in scientific literature. The problem of using Common Cocklebur in the context of modern evidence-based medicine is becoming increasingly important.Text. This article examines the chemical composition of common cocklebur based on studies published from 2005 to 2022. The composition of the essential oil as one of the main components is described in detail, and the comparison of the essential oil component composition of various chemotypes of cocklebur collected in different regions of the world is considered. Data on the composition of flavonoids, phenylpropanoids and steroids, alkaloids, fatty oils, resins, polysaccharides, amino acids, vitamins, glycosides and other compounds is considered. The structures of the main chemical components characteristic of the common cocklebur are given. The article presents data on experimentally confirmed types of biological activity. The experience of using cocklebur extracts in studies of antibacterial, antifunginal, scolicidal and antitrypanosomal activities is considered. In addition, information is provided on experimentally confirmed types of biological activity: antidiabetic, antitumor, anti-inflammatory, antioxidant and analgesic.Conclusion. Based on the literature date, Xanthium strumarium L. can be considered not only as an invasive and polluting species that has actively spread almost all over the globe, but also as a potential medicinal plant with a rich chemical composition.

The corrosion behaviors of newly developed solder alloys with excellent mechanical properties, Sn-2.5 Ag-1.0 Bi-0.8 Cu-0.05 Ni (SABC25108N) and Sn-1.5 Bi-0.75 Cu-0.065 Ni (SBC15075N), are analyzed to supplement the corrosion behavior of the limited corrosion data in Pb- and Zn-free solder compositions. A potentiodynamic polarization test is conducted on these compositions in a NaCl electrolyte solution, the results of which are compared with those of conventional Sn-3.0 (wt%) Ag-0.5Cu and Sn-1.2Ag-0.5Cu-0.05Ni alloys. The results indicate that SBC15075N exhibits the lowest corrosion potential and highest corrosion current density, thus signifying the lowest corrosion resistance. By contrast, SABC25108N exhibits the lowest corrosion current density and highest corrosion resistance. Notably, SABC25108N shows a slower corrosion progression in the active state and exhibits the longest passive state. The difference in corrosion resistance is affected more significantly by the formation and distribution of the Ag3Sn intermetallic compound phase owing to the high Ag content instead of by the presence of Bi or Ni. This uniform dispersion of Ag3Sn IMC phases in the SABC25108N alloy effectively suppressed corrosion propagation along the grain boundaries and reduced the formation of corrosion products, such as Sn3O(OH)2Cl2, thereby enhancing the overall corrosion resistance. These findings provide valuable insights into the optimal design of solder alloys and highlight the importance of incorporating sufficient Ag content into multicomponent compositions to improve corrosion resistance.

Abstract Developing nanoporous high-entropy metallic glass (HEMG) with a high specific surface area presents a promising approach to develop a cost-effective and efficient catalyst, which utilize the synergistic effect of its multi-component composition and the adjustable atomic environment of its disordered structure. However, the glassy structure invariably gets erased due to the inevitable crystallization during the nanoporous construction procedure through dealloying. Here, an innovative HEMG with an endogenetic nano-scale phase-separated structure is specially designed to maintain a fully glassy state throughout the nanoporous construction procedure. Consequently, an amorphous/crystalline heterostructure (ACH)—nanocrystal flakes embedded in amorphous ligaments—is intentionally constructed, which exhibits significant lattice distortion at amorphous/crystalline interfaces, resulting in high density of active sites. The ACH facilitates intermediate adsorption by promoting directional charge transfer between amorphous and crystalline phases and improves product desorption through downshifting the d-band center. This results in remarkable electrolysis performance, requiring only a 1.53 V potential to achieve a current density of 10 mA cm−2 for overall water-splitting in an alkaline electrolyte, surpassing that of commercial Pt/C || IrO2 catalysts of 1.62 V. This research pioneers strategies to refine the composition, atomic structure, and electron characteristics of HEMG, unlocking new functional applications.

Volatile Organic Compounds (VOCs) are essential for primary pharmaceutical manufacturing. Their permissible emission levels are strictly regulated due to their toxic effects both on human health and the environment. Activated carbon adsorption columns are used in industry to treat VOC gaseous waste streams from industrial plants, but their process efficiency suffers from quick and unpredictable saturation of the adsorbent material. This study presents the application of a validated, non-isothermal, multicomponent adsorption model using the Langmuir Isotherm and the Linear Driving Force model to examine multicomponent VOC mixture breakthrough. Specifically, three binary mixtures (hexane–acetone, hexane–dichloromethane, hexane–toluene) are simulated for four different bed lengths (0.25, 0.50, 0.75, 1 m) and six different superficial velocities (0.1, 0.2, 0.3, 0.5, 0.7, 0.9 m s−1). Key breakthrough metrics reveal preferential adsorption of acetone and toluene over hexane, and hexane over dichloromethane, as well as breakthrough onset patterns. Temperature peaks are moderate while pressure drops increase for longer column lengths and higher flow rates. A new breakthrough onset metric is introduced, paving the way to improved operating regimes for more efficient industrial VOC capture bed utilisation via altering multicomponent mixture composition, feed flowrate, and column length.

Titanium based nanocomposites owing to their remarcable properties of the coating surfaces have been synthetized and investigated in different combination and forms, such as multi-component composites. The binary combination presented in this work will refer to Ti:X (X=Ag, C, Cr), deposited by the innovative Laser Induced-Thermionic Vacuum Arc LTVA method. The deposited thin films were characterized by means of a scanning electron microscope technique (SEM) energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and transmission electron microscopy (TEM). The wettability of the deposited Ti:X thin films was investigated by the surface free energy evaluation (SFE) method. The purpose of our study was to prove the potential applications of Ti-based thin films in fields, such as nanoelectronics, fuel cells, medicine, and materials science.

Introduction: Improving existing and developing new methods for treating local radiation injuries (LRI) of the skin is very important. One of the promising areas in this area is the development of preparations – hydrogels (H) with high regenerative potential, obtained from lyophilisates of decellularized biological tissues (LDT). Due to the multicomponent composition and the presence of such connective tissue components as collagen, laminin, fibronectin, elastin, as well as growth factors, such hydrogels stimulate cellular migration and adhesion, and also maintain their viability and functional activity in the wound bed. To improve the ease of use (improving the mechanical properties of the drug), as well as slowing down the biodegradation process, H-LDT preparations are modified, in particular, by the method of chemical cross-linking with genipin (GNP). Objective: To evaluate the effectiveness of using a modified hydrogel preparation in the treatment of local radiation skin lesions in laboratory animals. Material and methods: Local radiation injuries were modeled in 15 laboratory animals (male Wistar rats, average weight 225.0±25.0 g) using an LNK-268-PS X-ray machine. MLP treatment was performed with a hydrogel from lyophilisate of decellularized human tissues (H-LDT), obtained by a modified method of dry-cleaning cross-linking with genipin (GNP: 0.2 mM) on days 28–32, 35, 42 after irradiation. The animals were divided into 3 groups (5 animals in each) depending on the type of therapy: control group without therapy; H-LDT group; H-LDT+GNP group. Observation of laboratory animals was carried out up to 119 days with planimetric and histological examination (hematoxylin and eosin staining) of the course of the wound process of MLP. Results: Planimetric studies have shown that the area (S) of the open wound surface (OWS) decreased by 30 % of the total S lesion in the experimental groups of animals (Н-LDH and H-LDH+GNP) on day 56 compared to the control group – on day 70. On day 119 of observation, healing of the LRI and the absence of OWS were noted in 40 % of animals in the H-LDT group. In the H-LDH+ GNP group, from day 28 to day 119 of observation, a decrease in S OWS by 6.15 times was noted compared to the control group of animals – by 3.49 times. In the H-LDT group, the results of histological studies demonstrated weak inflammatory infiltration, healing of the LRI and the absence of inflammatory infiltration and necrosis zone, the presence of single hair follicles. Conclusion: Thus, the present study showed that hydrogel preparations from lyophilisate of decellularized human tissues and hydrogel modified with genipin have a positive effect on the dynamics of the course of the wound process of LRI in laboratory animals, no irritating effect on the skin was detected.

Bacterial cellulose (BC)-derived carbon nanofiber aerogel shave promising applications in the field of electromagnetic wave (EMW) absorption. However, the high permittivityinduced poor impedance matching and the single loss mechanism lead to weak EMW absorption performance. Assemblinginto the ordered structure can establish a continuous conductive network, thereby augmenting the conductive loss and enriching the loss mechanisms. Herein, an ordered structure carbon nanofiber aerogel anchored with FeCoNi medium entropy alloy (MEA) nanoparticles (CNA@FeCoNi) is fabricated via directional freeze-drying and hydrogen thermal reduction strategy. The incorporation of FeCoNi MEA nanoparticles can not only introduce magnetic loss but also enhance impedance matching by reducing the dielectric constants. In addition, FeCoNi MEA nanoparticles trigger strong polarization loss due to the lattice distortion arising from the multi-component composition. Consequently, the fabricated CNA@FeCoNi presents remarkable EMW absorption performances with the minimum reflection loss (RLmin) value of -56.7dB at an ultra-low filler of 5 wt.% and the effective absorption bandwidth (EAB) reaches 5.28GHz. Besides, radar cross-section (RCS) simulation analysis and infrared radiation (IR) images deliver excellent application potential for both civilian and military purposes.

Linen materials have a multicomponent biopolymer composition, which makes it possible to use the selective action of different types of enzymes in the processes of their biomodification. The selection of enzymes provides a controlled change in the physical and mechanical properties of raw materials, semi-finished products and final products, as well as an increase in the chemical activity of the fiber in interaction with functional reagents. The purpose of the work is to substantiate technological approaches to comprehensively achieve the effects of reducing excessive stiffness of flax fiber while increasing its elasticity. The research is aimed at developing a promising technology for bio-softening and increasing the resistance of linen products to creasing. The use of strongly adsorbed cellulases with large (more than 30 nm) globule sizes reduces of tissue stiffness due to localized destruction of cellulose fibrils in the primary cell wall of flax fiber. The bio-treatment is complemented by the application of aqueous polyurethane dispersions to the fabric. The assessment of the polyurethane condition was carried out using the methods of differential scanning calorimetry and FT-IR spectroscopy. The analysis of the physical and mechanical properties of the fabric was carried out using standard methods of textile materials science. The studies confirm the difference between the results of the combined effect of cellulases and polyurethane ionomers on linen fiber from the effects that accompany the traditional processes of film formation of polyurethane dispersion on textile materials. The biocatalyzed rupture of the glycoside bond in cellulose macromolecules initiates the interaction between the resulting pyranose end links in semi-acetal form and the amino groups of polyurethane. The combined processing of linen fabric increases the crease resistance in the dry and wet state of the fiber by 1.4-1.6 times, combined with a decrease in bending stiffness by 2.2-2.7 times. For citation: Aleeva S.V., Shipova S.E., Shammut Yu.A., Kornilova N.L., Koksharov S.A. Study of polyurethane ionomers transformations in the bio-softening of materials for linen clothing. ChemChemTech [Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol.]. 2025. V. 68. N 7. P. 125-137. DOI: 10.6060/ivkkt.20256807.7205.

The soil microbiome of agricultural crops is a key component of agroecosystems, influencing the growth, development and resilience of plants in the agrocenosis. All plant-microorganism interactions are not random and are the result of long-term coevolu­tion, often leading to associations in which the host (plant) and its microbiota cooperate in a mutually beneficial manner. Biofilm formation is a strategy used by microorganisms to stably colonize the root surface of plants. Biofilms consist of microorganisms embedded in a self-produced extracellular matrix that provides protection against environmental stresses and plant immune responses. The study of the ability of microorganisms to form biofilms and adhesion on plant roots is one of the elements of the formation of the microbiome of agricultural plants under the ac­tion of biological preparations, individual strains or multicomponent compositions of soil microorganisms. Understanding the process of biofilm formation on plant roots allows us to predict and develop strategies for interactions between plants and microorganisms to mitigate abiotic stress, namely drought, salinization and heavy metal pollution and the formation of sustainable productive agroecosystems. In a laboratory experiment, the adhesive properties and ability to form biofilms of microorganisms-agents of the Diamond grow organic-mineral fertilizer brand HUMI [K] BIO+ «PLUS» (OMD DG H[K]B «Plus») on the roots of seedlings of test crops of agricultural plants were determined. The uniqueness of OMD DG H[K]B «Plus» lies in the fact that its composi­tion combines a complex of macro and microelements, humic acids, algae extract, and a complex of strains of 16 microorganisms of the genera Bacillus, Glomus Rhizopogon, Pisolithus, Scleroderma. A number of ag­ricultural plants were selected as test crops: spring wheat Tokata, barley Sebastian, corn Khorol, cucum­ber Rodnychok F1, sweet pepper Ivanhoe, tomato Sanka, zucchini Eleonora F1, beans Shahinya, chick­ peas Triumph, vegetable peas Dragon, seed peas Mae­cenas, pumpkin West. During the study, it was found that the level of biofilm formation and formation on the roots of seedlings of test crops significantly depended on the species of plants, and less on the con­centration of the applied OMD DG H[K]B «Plus». After 48 hours of the study, the formation of biofilms was noted on the roots of all the studied test crops, but with different levels of formation. It was found that the lowest density of biofilm was demonstrated by test crops of the Fabacae family, the highest by Poacae. As a result of the study, it was found that the intensity of biofilm formation and microbial adhesion decreased in the following sequence: corn > wheat > barley > tomatoes > peppers > cucumbers > zucchini > field peas > chickpeas > vegetable peas > beans.

Background: By now Russian and foreign scientists have proposed many different compositions of multicomponent mixed fuels (MMF), as well as methods of high-temperature boosting. It is known that poor-quality tuning of fuel injection equipment (FIE) leads to an increase in costs up to 30...35%, decreases the internal combustion engines lifespan by 1.5 ... 2 times, worsens their performance. The study of the operation of the FIE with non-conventional fuels and under conditions of thermal boosting of diesel fuel is of particular interest. Objective: Study of the efficiency of diesel fuel injection equipment in non-conventional conditions. Methods: In the experimental study, the bench for adjustment of the KI-22210-02M-11 diesel fuel injection equipment when operating with pure diesel fuel without heating, heated to 100 °C and heated to 150 °C was used. At the second stage, comparative tests were carried out on multicomponent compositions of mixed fuels, including diesel fuel, cold-pressed rapeseed oil (RSO) and rectified ethyl alcohol. Results: According to the test results, the full load curves of the high-pressure fuel pump with the regulator turned on at the full speed range were built. The effect of diesel fuel heating, as well as the fragmentation of the composition of the multicomponent mixed fuel on the value of the cyclic supply and its unevenness has been found. The scientific novelty of the study lies in determining the need for adjustments of the fuel pump to achieve the cyclic supply parameters set by the manufacturer and predicting the reliability and durability of the fuel injection equipment when operating in non-conventional conditions. Conclusions: The practical value of the study lies in the opportunity of using the proposed compositions of multicomponent mixed fuels and diesel fuel heating modes during diesel operation.