Environment in arid conditions is dynamic and needs more investigation to understand the complexity of change. This spatiotemporal study will help to assess and monitor the land use and land cover change in the arid region of El-Arish area, where the climate and human activities are the major threats to rural development. In the past 11 years, dramatic changes of environment have been recorded in case studies. The post-classification comparison method was used to observe the changes using multi-temporal satellite images which were captured in the years 1999, 2001, 2005, and 2010. The overall accuracy of the produced thematic images was assessed regarding to the quantity and allocation disagreements. Five classes were defined in this investigation: bare soil, vegetation, urban, sand dunes, and fertile soil. From the year 1999 to 2010, fertile soil was increased by 13 %. Bare soil class occupied more than 50 % of land in the case study during for over a decade. From year 1999 to 2010, vegetation cover witnessed a dramatic increase. Soil and water management are the keys of land development and positive land use and land cover dynamics. Changing agricultural policies of using the available water resources are needed in the case study to prevent severe food shortage in the future.