Cancer patients who undergo organ transplantation after oncologic treatment experience complex biological and psychological stressors that jointly influence immune recovery and graft function. Psychological distress—particularly anxiety and depression—activates neuroendocrine and autonomic pathways that modulate cytokine release, inflammation, and immune tolerance. Evidence from psycho-oncology and transplantation studies demonstrates that heightened distress and low resilience correlate with increased interleukin-6, tumour necrosis factor-α, and C-reactive protein levels, impaired cellular immunity, and delayed post-operative recovery. This review integrates current findings from psychoneuroimmunology, transplantation medicine, and behavioural oncology to elucidate how donor characteristics, perfusion parameters, and psychosocial factors interact to shape outcomes in cancer-related transplantation. Routine psychological assessment using validated instruments such as the Hospital Anxiety and Depression Scale (HADS), together with early interventions—cognitive-behavioural therapy, mindfulness-based stress reduction, and resilience training—may reduce inflammatory activity and improve recovery trajectories. Furthermore, emerging multimodal and machine-learning-assisted analytic approaches provide opportunities for personalised psychosocial care and risk stratification. Understanding these psych neuroimmune interactions supports the development of integrative, precision-based rehabilitation strategies within the scope of psycho-oncology.

Comparative effects of mind-body exercises on anxiety and depression in patients with chronic obstructive pulmonary disease: A network meta-analysis of randomized controlled trials.

Effects of maternal Mediterranean diet on fetal cardiac function in high-risk pregnancies: a secondary analysis of the IMPACT BCN randomized trial.

ABSTRACT This article presents a therapeutic approach to address the complex aftermath of child sexual abuse in Black women. The proposed approach combines mindfulness-based stress reduction with the strong Black woman model, focusing on empowerment and community support as crucial components of trauma recovery, while considering the intersections of race, culture, gender, and trauma, and the neurobiological implications. It offers a culturally responsive intervention with clear implications for social workers.

Families caring for children with autism spectrum disorder (ASD) often encounter persistent stress, stigma, and limited support systems. Despite these challenges, many demonstrate resilience-the capacity to adapt and sustain well-being under adversity. This integrative review synthesizes conceptual frameworks and interventions designed to strengthen family resilience in ASD caregiving. A systematic search across PubMed, Scopus, CINAHL, and Google Scholar (2000-2025) yielded 55 eligible studies. Seven resilience models were identified: protective factors, transactional, ecological systems, CARE, mindfulness-based stress reduction, Triple-A, and strengths-based approaches. Interventions informed by these models produced measurable benefits, including reductions in parental stress and caregiver burden, alongside gains in family cohesion, psychological health, and quality of life. The review underscores the importance of culturally adapted, multidisciplinary, and scalable resilience-building strategies, while calling for standardized evaluation tools and policy integration to ensure sustainable support for families raising children with ASD.

The current study was conducted to determine the effects of a 6-week mindfulness-based stress reduction (MBSR) program provided to parents of children with autism spectrum disorder (ASD). The study had an experimental design based on a pre-/posttest model with experimental (n = 40) and control (n = 40) groups. Parents of children with ASD who attend education and rehabilitation centers were included in the MBSR program, which taught effective coping using stress methods, breathing meditation, sitting meditation, body scan, and mindful eating. Upon completion of the MBSR program, participants showed a significant increase in posttest (mean = 78.525) compared to pretest (mean = 57.925) mindfulness (t = -11.221; p < .01; d = 1.774; 95% confidence interval [-24.313, -16.887]). There was no change in the control group. Posttest scores increased significantly compared to pretest scores for self-confident and optimistic approaches, and posttest scores for helpless and submissive approaches also showed significant differences (t[78] = -3.208; p < .05). The MBSR program provided to parents of children with ASD was effective in increasing mindfulness and coping with stress. Parents' mindfulness can contribute to reducing their children's stress levels and making their lives meaningful.

This randomized controlled trial investigated the effects of the Mindfulness-Based Stress Reduction (MBSR) program on stress, subjective anxiety, self-compassion, and prenatal attachment in pregnant women with perinatal loss. A total of 112 women were randomly assigned to MBSR (n = 56) or control (n = 56) groups. The MBSR program was delivered face-to-face in eight sessions over 4 weeks. Pretest comparisons showed no significant differences between groups (p >.05). Posttest results indicated that the MBSR group had significantly lower Tilburg Pregnancy Distress Scale (partner involvement and negative affect) and Subjective Units of Disturbance Scale scores, with large effect sizes (η2 = .677, .679, .143, .621). The MBSR group also showed significantly higher Self-Compassion Scale-Short Form scores (η2 = .542) and higher Maternal Antenatal Attachment Scale scores, including both time spent on attachment and attachment quality (η2 = .620, .760, .557). Findings suggest MBSR effectively reduces stress and anxiety while enhancing self-compassion and prenatal attachment in women with perinatal loss.

Active involvement in creative activities, known as creative health, has been shown to enhance wellbeing, with museums serving as unique spaces for health promotion; however, visitors often require guidance to derive significant benefits from these institutions. This study, part of the larger ASBA (Anxiety, Stress, Brain-friendly museum Approach) project, evaluates the first phase of an intervention specifically focused on a Mindfulness protocol adapted to museum contexts. It has employed a single-group pre-post design with 79 healthy adults recruited from the non-clinical population. Participants were involved in a 15 min standardized mindfulness practice adapted from Mindfulness-Based Stress Reduction (MBSR) in either an art or science museum. State anxiety (SAI) and mood (VAS) were assessed at baseline and post-intervention, alongside personality traits (BFI-10) and interest measures to identify individual moderators of treatment response. The practice appeared to reduce state anxiety significantly in both settings, with large effect sizes. Specific moderators emerged: openness to experience predicted anxiety reduction in the art museum, whereas science interest predicted outcomes in the science setting. These findings suggest that brief, standardized mindfulness protocols implemented through the ASBA framework can provide promising immediate benefits for visitor wellbeing across diverse museum environments.

Backgrounds/Objectives: Mindfulness-based stress reduction (MBSR) programs may have applications for adults with cerebral palsy (CP), particularly as this population is at increased risk of mental health challenges relative to the general population. However, little is known about the experiences of adults with CP participating in these programs. The aim of this study was to explore the experiences of adults with CP, and a facilitator, who participated in a 9-week MBSR telehealth program. Methods: Adults who attended an MBSR telehealth program were invited to participate in focus groups. If a participant was unable to attend a focus group, they were offered a semi-structured interview. The facilitator participated in a semi-structured interview. Focus groups and interviews were recorded, transcribed verbatim, and inductively thematically analyzed using Framework Analysis. Results: Ten adults with CP and one facilitator participated. Feedback on the program spanned across three themes: (i) learning and creating my mindfulness toolbox; (ii) applying mindfulness to everyday life; and (iii) online together with expert facilitation. Participants appreciated having access to a variety of mindfulness techniques to accommodate individual preferences. Peer-learning in a facilitated, online group context was also valued. Participants recalled implementing mindfulness strategies in everyday life and provided recommendations of how to improve the program. These included incorporating a group orientation, shortening group sessions to reduce fatigue, and follow-up sessions to maintain mindfulness skills after program completion. Conclusions: This study provides new knowledge about the perspectives of adults with CP regarding MBSR delivered via telehealth. Participant recommendations should inform future implementation of group mindfulness telehealth programs for adults with CP.

Mindfulness-Based Stress Reduction Enhances Quality of Life and Positive Psychological Traits Among Head and Neck Cancer Patients: Findings from a Randomized Controlled Trial

Optimal doses of mind-body exercise on neuroinflammation in individuals with neuropsychiatric disorders: A systematic review and dose-response meta-analysis

ABSTRACT This study examined the relationship between empathy and compassion fatigue in 334 Australian school teachers. Specifically, the study examined the relationship between cognitive and affective empathy on compassion satisfaction, burnout, and secondary traumatic stress (STS). The latter variables were measured using the Professional Quality of Life Scale (ProQOL). Participants also completed demographic items and the Questionnaire of Cognitive and Affective Empathy (QCAE). Multiple regression analysis revealed weak but significant associations between the study’s key variables. Cognitive empathy was positively associated with compassion satisfaction and negatively associated with burnout and STS. In contrast, affective empathy was negatively associated with compassion satisfaction and positively associated with burnout and STS. Age, teaching experience, and school location were also found to influence compassion satisfaction and burnout in teachers’ professional quality of life. This study emphasises the importance of balancing cognitive and affective empathy for teachers’ professional wellbeing. Affective empathy, while crucial for relationships, must be complemented by cognitive empathy to prevent burnout and compassion fatigue. Practical options to combat compassion fatigue in teachers are explored, highlighting the potential benefits of peer support, mindfulness-based stress reduction, reflective practice, and distributed leadership in Australian schools.

Mindfulness-based stress reduction (MBSR) has been shown to improve mental health and well-being in people with different medical conditions. However, whether it improves outcomes in chronic stroke populations is less clear, as few studies have examined the efficacy of MBSR in this population with a randomized controlled trial and an active control condition. Our study aimed to address this gap. People with a history of chronic stroke (n = 59) participated in a randomized controlled trial of MBSR. They were randomly assigned to an online MBSR intervention or an online Brain Health Education intervention. Both interventions were matched on a number of variables, including schedule, instructor, and format. Participants were assessed pre-, post-, and 6 months postintervention using online questionnaires and an online neuropsychological battery. MBSR did not lead to improved anxiety F(2, 55) = 1.13, p = .321, η² = .01) or depression F(2, 68) = 0.53, p = .588, η² = .002) symptoms over time. Exploratory outcomes of cognitive functioning, physical health, and well-being also revealed no MBSR-specific improvements over time (ps > .318). People with a history of chronic stroke reported improved outcomes from participating in either intervention, providing support that both online MBSR and Brain Health Education interventions are feasible and low-cost interventions for this population. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

IntroductionEngaging community members and context experts is increasingly recognized as key to developing research that is responsive to community needs. Here, we describe a protocol for incorporating stakeholder feedback using rapid qualitative techniques into OPTIMUM (Optimizing Pain Treatment In Medical settings Using Mindfulness), a pragmatic clinical trial comparing a telemedicine-delivered mindfulness-based stress reduction intervention to usual care to address chronic low back pain. The aim of this stakeholder feedback supplement to the OPTIMUM parent trial is to consider many viewpoints regarding recruitment, retention, facilitation, delivery, sustainability, and dissemination of this program which are critical to understand before it can be successfully implemented.MethodsOur team developed a multi-faceted approach to collecting feedback from representatives of three levels of influence: individuals, communities, and policy. We plan to conduct focus groups with study participants from both the intervention (MBSR) and usual care groups. We plan to conduct one-time semi-structured interviews with a diverse set of people with varied roles and perspectives (e.g., clinic personnel, health care system leadership, mindfulness instructors, patient pain advocacy groups, policy advocates). We will assemble a Community Advisory Board (CAB) to convene regularly throughout the project. Transcripts from interviews, focus groups, and meeting notes will be analyzed using rapid qualitative methods to facilitate timely incorporation of feedback into the trial. In-depth thematic content analysis will be conducted subsequently.DiscussionPartnering with communities who are historically underrepresented in clinical research under the guidance of principles such as equity, inclusion, trust, and accountability can improve health outcomes that are most relevant and beneficial to the target community, accelerate uptake, and promote sustainability.

Neural mechanisms underlying the depression-reducing effects of mindfulness-based stress reduction in university students: A Rs-fMRI study.

The impact of mindfulness-based stress reduction therapy on individuals with autism spectrum disorder and their caregivers: A systematic review.

Reducing stress among nurses: The impact of mindfulness-based stress reduction programs.

Circadian and gut-brain axis modulation is associated with neuroimmune and symptom recovery after rectal cancer surgery: An exploratory randomized controlled trial.

The effects of mindfulness-based stress reduction (MBSR) interventions on nursing student performance and well-being: A systematic review

Emotional regulation is an important aspect in maintaining the mental health of the elderly, especially those suffering from chronic diseases such as Type 2 Diabetes Mellitus. Chronic disease conditions often trigger psychological stress that impacts an individual's ability to manage emotions. One of the non-pharmacological interventions widely developed to overcome stress is Mindfulness-Based Stress Reduction (MBSR). This study aims to determine the effect of MBSR on emotional regulation in elderly with Type 2 Diabetes Mellitus in Bangun Rejo Village in 2025. This study used a quantitative design with a one-group pretest–posttest method. The study subjects were 30 elderly with Type 2 Diabetes Mellitus selected using a total sampling technique. The MBSR intervention was given for eight sessions, and emotional regulation was measured using the Emotion Regulation Questionnaire (ERQ) before and after the intervention. Data analysis was performed using descriptive statistics and the Paired Sample t-Test. The results showed a significant increase in emotional regulation scores, from an average of 34.67 before the intervention to 75.50 after the MBSR intervention. Statistical test results showed a significant difference between pretest and posttest scores (p &lt; 0.05). Thus, MBSR has been proven effective in improving emotional regulation in elderly people with Type 2 Diabetes Mellitus. The MBSR program is recommended as a supporting intervention in elderly health services.