The cover picture shows…︁‥individual F‐actin filaments in lithographic microchannels (fluorescence microscopy image in the foreground, channel width 6 μm). Real‐time observation of the fluctuations of the fluorescently labeled molecules within the channels yields insight into the statistical mechanics of biopolymers in confined geometry. The impact of various geometrical parameters, such as channel curvature, may be studied by means of more intricate microfluidic setups (bright‐field microscopy image in the background). The goal is to understand the influence of geometric confinement, such as is present in microfluidic devices or in living cells, on the dynamics of complex matter. Find out more in the Concept Article by Herminghaus et al. on pp. 1291–1298.