Method Of Mathematical Planning Research Articles

Study of excipients quantities influencein the composition of the powder in sachet packages

For developing power in sachet packages with anti-inflammatory action a special task is optimal qualitative and quantitative composition of excipients. The purpose was to study the effect of excipientʼs quantities on the pharmaco-technological parameters of power.Methods. It was composed of various compositions of active components and excipients using the method of mathematical planning of the experiment. By random balance method was studied their effects on the physico-chemical, technological and organoleptic properties of powder.Results. Analysis of the scattering diagrams for influence of quantitative factors on the mass appearance showed that the most significant on this indicator are quantities of calcium phosphate, sodium citrate, curcumin and lemon-lime flavor. Significant factors for bulk density and density after shrinkage are quantities of calcium phosphate, sodium citrate, lemon-lime flavor and titanium dioxide. The results of Carr Index are most influenced by the quantities of acid lemon-lime anhydrous, titanium dioxide and curcumin. Experimental values of fluidity are most depend on quantity of calcium phosphate. Quantities of calcium phosphate, sodium citrate and titanium dioxide are the most significant for the slope angle. The greatest influence on the mass loss rates during drying show the quantities of curcumin and malic acid. On the basis of the scattering diagram for appearance of the solution the decisive influence of quantities of calcium phosphate, sodium citrate, lemon-lime flavor and titanium dioxide was determined. Obviously, the significance of the quantity of lemon-lime flavor on smell of the solution. Analysis of the dispersion diagram for taste of the solution showed that the most important are quantities of calcium phosphate and acid citric anhydrous. The most significant factors for pH of the solution are the quantities of phosphate calcium and lemon-lime flavor.Conclusion. The effects of excipientʼs quantities on pharmaco-technological and organoleptic properties of the powder in sachet packets is investigated

Determination of the enzyme destruction rational mode of biomass autolysate of lactic acid bacteria

It is shown that the degradation products of peptidoglycans of lactic acid bacteria cell walls that are related to the muramyl peptide series compounds are promising components of food ingredients and dietary supplements for the nutritional support of the population suffering from disorders of the immune system. The expediency of autolysis of lactic acid bacteria biomass to increase the enzymatic degradation efficiency of peptidoglycans of their cell walls has been proven. The accumulation of low molecular weight peptides in the enzymatic hydrolysis of biomass under rational parameters, which was not subjected to autolysis, is 0.260 mg/cm 3 , in the enzymatic hydrolysis of biomass that was subjected to autolysis is 0.569 mg/cm 3 . Rational regimes of enzymatic hydrolysis of the composition of lactic acid bacteria (enzyme concentration of 12.5 mg/cm 3 , substrate concentration of 70.0 mg/cm 3 , duration of enzymatic hydrolysis of 245.6 min) were determined using mathematical planning methods of multifactorial experiments, which made it possible to significantly optimize and improve the work efficiency. The affiliation of low molecular weight peptides obtained under the rational conditions of enzymatic hydrolysis to immunological compounds of the muramyl peptide series has been proven by gel chromatography and IR spectroscopy methods. It is determined that the molecular weight of the obtained low molecular weight peptides is in the range of 294 – 650 Da, which, in fact, corresponds to the molecular weight of muramyl dipeptide and glucosaminylmuramyl dipeptide. In the IR spectrum of low molecular weight peptides, the absorption bands are noted, which correspond to fluctuations of free amino groups, peptide bonds, which, in fact, occur in the structure of peptides, pyranose glucose forms that are part of muramic acid and N-acetylglucosamine of peptidoglycan, muramyl dipeptide and glucosaminylmuramyl dipeptide. Also, fluctuations of β-glycoside bonds, which binds the remains of muramic acid and N-acetylglucosamine in peptidoglycan and glucosaminylmuramyl dipeptide are marked in the IR spectrum of low molecular weight peptides

Effect of Complex Organo-Mineral Modifier on the Properties of Corrosion-Resistant Concrete

This paper reports the results of a research study aimed at identifying the compositional features of fly ash (FA) TPP “Pha Lai” (Vietnam), silica fume SF-90 (SF90) and superplasticizer SilkRoad SR 5000F (SR5000) contents that influence the sulfate resistance of corrosion-resistant concrete. The effect of FA, SF90 and SR5000 on the strength of corrosion-resistant concrete is obtained quickly, high early-strength concrete. In details, the compressive strength at the age of 1 and 3 days are respectively 29.6% and 61.13% in comparison to 28 days period. The deformation of corrosion-resistant concrete prisms in 5% sodium sulfate solution after 28 days of testing were determined by Russian standard GOST P 56687-2015. Using the mathematical planning method for four factors and the Matlab computer programs was obtained the mathematical model, which was adequately described the influence ofthe water-binding ratio, FA, SF90 and SR5000 contents on the concrete deformation. It was also noted that the effect of FA content is more pronounced than the water-binding ratio and content SF90. In addition, the effect of SR5000 content on the deformation of concrete is negligible, so it was discarded.

数理的計画手法の応用と展開 : オフィスからインテリアやプロダクト(研究奨励賞)

数理的計画手法の応用と展開 : オフィスからインテリアやプロダクト(研究奨励賞)

Use of Repeated Fluoropolymer Suspensions to Obtain Composite Electrochemical Coating Based on Zinc

This article deals with the issues of utilization of the waste products of fluoropolymers, namely, the suspensions of fluoroplasts that have lost their consumer properties. Such waste is recommended to be used as a filler of zinc coatings to provide increased corrosion resistance. Using the method of mathematical planning of the experiment, the authors establish the optimal compositions of galvanizing chloride-ammonium electrolytes to obtain the corrosion-resistant composite electrochemical coatings (CEC) of zinc-fluoropolymer. As a result, coatings with a finely crystalline structure were obtained differing in the distribution pattern on the surface of the samples and depending on the variation in the zinc concentration in the electrolytes. The samples of steel reinforcement with the zinc-fluoropolymer coating were tested on corrosion resistance. The increase of anticorrosive properties in CEC zinc-fluoropolymer and a slight decrease in microhardness were indicated.

THE RESEARCH OF THE STRUCTURE FORMATION PROCESSES OF DISPERSE MATERIALS AT THE OBTAINING OF THE COMPOSITE BUILDING MATERIALS WITH PREDETERMINED PROPERTIES

The basic concepts of the developed theory of the structure formation of dispersed materials in the preparation of composite building materials (CBM) with predetermined properties are proposed in the article. It is shown that, in addition to laborious methods of mathematical planning, low-cost research methods, for example, thermal methods, can be used to predict the properties of CBM. The data of differential scanning calorimetry, microscopic analysis, confirming the hypothesis that the thicknesses of water films on the surface of particles of disperse systems affect the formation of nano- and microstructures of CBM are presented. On the basis of VSTU in the center of collective use of the name of Professor Yu.M. Borisov conducted a number of tests on instruments of various domestic and foreign manufacturers, such as the RAULIKD derivative, the automatic diffractometer PANalytical EMPYREAN, the X-ray diffractometer DRON-2 and others using laser diffraction, synchronous thermal analysis. On the basis of the conducted experiments, the following conclusions were made: the IPFM systems with a phosphogypsum dihydrate content of 50 ... 60%, 10% lime, sandy loam 40 ... 30% possess the best physical-mechanical properties, water absorption and softening coefficients; drying at temperatures of 60 ... 65 ° C of the obtained materials leads to a decrease in the thickness of the water films between the particles and promotes further strength growth; an understanding of the mechanism of the effect of the thickness of aqueous films on the processes of the formation of hydrate hydrophilic systems allows us to predict that various technological methods leading to a reduction in their thickness will lead to an increase in the strength and other indices of materials obtained from non-flammable technologies.

ВИВЧЕННЯ ВПЛИВУ ДОПОМІЖНИХ РЕЧОВИН НА ФАРМАКО-ТЕХНОЛОГІЧНІ ВЛАСТИВОСТІ ТАБЛЕТОК СУХОГО ПОРОШКУ БІОМАСИ FLAMMULINA VELUTIPES

Мета роботи. Вивчити вплив чотирьох груп допоміжних речовин (наповнювачі, розпушувачі, змащувальні та ковзні, зв’язуючі) на фармако-технологічні властивості таблеток сухого порошку біомаси Flammulina velutipes.Матеріали і методи. Дослідження впливу допоміжних речовин (ДР) на такі показники, як зовнішній вигляд, однорідність маси, стійкість до роздавлювання, стираність та розпадання таблеток проводили відповідно до вимог ДФУ 2 видання. Вивчення чотирьох груп ДР здійснювали за допомогою математичного планування експерименту.Результати й обговорення. На підставі множинних порівнянь рівнів вивчених факторів зроблено висновки про вплив ДР на показники якості таблеток сухого порошку біомаси F. velutipes. При використанні будь- якого із представників груп ДР одержували близькі результати впливу на однорідність маси таблеток. Задовільні результати стираності таблеток одержано у 13 серіях дослідів, з них 5 мали середній показник менше 0,5%. Спресовані таблетки сухого порошку біомаси F. velutipes мали різні показники міцності, лише у 9 серіях дослідів показник був вищим 50 Н. При вивченні впливу ДР на розпадання таблеток виявили 7 незадовільних серій препарату.Висновки. Встановлено вплив чотирьох груп ДР на такі фармако-технологічні характеристики таблеток сухого порошку біомаси F. velutipes, як зовнішній вигляд, однорідність маси, стійкість до роздавлювання та розпадання. Відібрано оптимальні представники досліджуваних груп ДР (цукор білий подрібнений, глина біла, кислота стеаринова, 2 % крохмальний клейстер) для отримання таблеток сухого порошку біомаси F. velutipes методом вологого гранулювання.

Selecting optimal structure of burners for tubular cylindrical furnaces by the mathematical experiment planning method

This paper substantiates the method of mathematical planning for experimental research in the process of selecting the most efficient types of burning devices for tubular refinery furnaces of vertical-cylindrical design. This paper provides detailed consideration of an experimental plan of a 4×4 Latin square type when studying the impact of three factors with four levels of variance. On the basis of the experimental research we have developed practical recommendations on the employment of optimal burners for two-step fuel combustion.

High-Velocity Air Plasma Spraying of (Ti, Cr)C–32 wt.% Ni Clad Powder

The influence of air plasma spraying (parameters such as plasma gun power, spraying distance, plasma gas flow, anode diameter) of (Ti, Cr)C–32 wt.% Ni clad powder on the characteristics of resultant coatings (structure, microhardness, porosity, phase composition) is studied. The experimental procedure is designed using the mathematical planning method. The experimental data are processed to derive regression equations, determining the quantitative dependence of average microhardness and stability of microhardness characteristics on spraying process parameters. It is found that plasma gun power and plasma gas flow have the greatest impact on microhardness of the coatings and ΔX/HVav parameter, which characterizes the reproducibility of coating properties. The spraying distance has hardly any influence on the properties studied within the test range (160–220 mm). The hardness of coatings produced from the (Ti, Cr)C–32 wt.% Ni clad powder (12.15–14.58 GPa) is higher than that of the coatings obtained by air plasma spraying of a mechanical mixture of 75 wt.% (Ti, Cr)C + 25 wt.% NiCr (5.3–12.6 GPa).

Effect of Charge Fractional Composition and the Coke Amount on the Parameters of Manganese Ore Agglomeration

Under laboratory conditions, the method of mathematical planning of experiments was used to study the effect of charge fractional composition (in the range of 2 to 8 mm) and the amount of coke in the charge (in the range of 7 to 13 wt.%) on the agglomeration process characteristics of the “Mamatwan” manganese ore (South Africa). It was found that the main agglomeration parameters vary within the following limits: the initial vacuum under grate – 54...140 mm WC for the charge layer of 350 mm; the maximum temperature – 1365...1440 °С; linear burning speed – 13,4...26,2 mm/min; the charge length of stay at temperatures over 1300 °С (the width of the melting zone) – 2,4...4,8 minutes. Mathematical equations of the combined effect of charge fractional composition and the amount of coke on agglomeration temperature, linear burning speed, width of melting zone (in time), initial vacuum in reactor were calculated. It was found that a major factor in providing the optimum mode of agglomeration is not the amount of coke, but the charge piece size distribution. For example, increasing the charge piece size has an 3,5 times more effective influence on the agglomeration temperature than the amount of coke. For the dust-containing charges the moistening up to 4...6 wt.% H2O is only partially solves the problem of the aerodynamic resistance. Pre-granulation of the dust fraction is needed to improve the gas permeability of the charge.

Use of Mathematical Planning Methods for Selecting Optimum Combined Gel Compositions

Science-based selection of the base-carrier for a combined gel dosage form containing phenylacetic-acid derivatives was studied. One-factor dispersion analysis with repeated observations was used. For this, gels with nine bases were prepared and characterized qualitatively. According to the results, one composition was eliminated from further experiments because of thermal instability. The release of active substances (benzketozone and diclofenac sodium) from the proposed gels was determined by Kruvchinsky equilibrium dialysis. The experiments confirmed that the base-carrier type influences significantly the release of active substances from gel compositions. Dispersion analysis results showed that a carrier based on Carbomer 934P gave the optimum release of active substances.

Modeling Dexterity Development in 2nd-4th-grade Boys by Means of Active Games

The objective is to optimize the mode of using game for dexterity development in the 2nd-4th-grade boys.Materials & methods: to conduct the experiment, there were eight test groups (n=48) formed in each class. The total number of such test groups was 24. The research relied on the following methods: theoretical analysis and collation of scientific and methodological literature; pedagogical testing; methods of mathematical experiment planning (complete factorial experiment 23); modeling method.Results: the research has determined that to develop dexterity, the 2nd-4th-grade boys need to participate in up to five games. The number of repetitions for the 2nd-3rd-graders is two, and for the 4th-graders – three, with 30–40-second rest intervals. The 2nd-4th-grade boys showed effective development during 40 classes, and the 3rd-grade boys – during 20 classes. After that, we recommend to use other means. The game duration varies from one to two minutes.Conclusions: the analysis of the scientific and methodological literature has revealed that the level of motor readiness, dexterity being one of its main components, largely determines the state of children’s physical and mental health. The research has found that the natural development of coordination abilities in boys aged between 7 and 10 is 22.5–80.0% (56.2% on average). Game actions play a particular role in dexterity development in junior schoolers.The 23 complete factorial experiment made it possible to study the multi-factorial structure of game load for the 2nd-4th-graders; to specify the relations between factors for their use during dexterity development in the 2nd-4th-grade boys in physical education classes. They can serve as an objective tool for the educational process optimization. The given regression equations are models that can be used to determine the optimal game means ratio in the academic process of the 2nd-4th-graders.

Modeling of Teaching University Students to Serve a Direct Volleyball Overhand

The objective is to determine the peculiarities of developing motor skills in the first-third-year students.Materials & methods: the participants in the study were male students of the first year (n = 32), second year (n = 32), and third year (n = 32) of training. To achieve the tasks set, the study relied on the following research methods: analysis of scientific literature, pedagogical testing, pedagogical observation and experiment. The study used the methods of mathematical planning of a complete factorial experiment to obtain a mathematical model of training modes.Results: the increase in the number of sets to twelve times, the number of repetitions in each set – to three times, and the rest interval – to 60 seconds positively impact the effectiveness of the first-third-year students’ training. The choice of training modes depends on the number of repetitions in a set for the first-year students; reduction in the rest interval to 60 seconds for the second-year students; the relation between the number of sets and the number of repetitions in a set for the third-year students.Conclusions: The 23-type experiment made it possible to study the multi-factorial structure of training modes of teaching technical elements to the first-third-year students; to specify the optimal relation between the number of sets, the number of repetitions in a set and rest intervals at the stage of teaching to serve a direct volleyball overhand.

Research of the oilseeds ratio on the oxidative stability of the protein-fat base for sportsmen

The problem of improving physical performance and accelerating the course of recovery processes after physical exertion is one of the most pressing problems of medicine and sports. Nutrition is one of the main controlled factors that ensure the normal development of the body, health and quality of life. Nowadays the assortment of products is mainly expanded due to introduction of new technologies, application of new chemical compounds, development of genetic engineering. At the same time, daily food cannot provide the athlete's body with nutrients in the required amount. And, as a result, in recent years, to speed up regeneration, actively replenish spent plastic and energy resources, very often in sports use biologically active additives. One of the promising areas for improving the efficiency of athletes is the introduction in food rations qualitatively new food products that meet the needs of their body and at the same time have a long shelf life. The aim of this study is to evaluate the oxidation processes of the protein-fat basis, which can be used to organize the rational nutrition of athletes. The oxidative stability of the crushed sunflower seeds, sesame seeds, flax and mixtures was studied at various component ratios. It has been established that sesame seeds are the least susceptible to oxidation, and most of all – flax seeds. Among mixtures of seeds, the most prone to oxidation are mixtures that contain flax seeds and sunflower seeds. When adding sesame seeds to the mixture, the oxidative stability increases sharply. The optimal content (% by weight) of oil seeds in a protein-fat basis was calculated using the method of mathematical experiment planning in the software package Statistica. The period of induction of oxidation of this mixture is 1.3 – 1.4 times higher than the induction period of sunflower seeds and 2.7 – 3.0 times higher than the induction period of flax seed. The use of such basis in food technologies, in particular the confectionery industry, opens up wide opportunities for expanding the range of specialized products for athletes.

Properties of dry masonry mixtures based on hollow aluminosilicate microspheres

At present, there is a steady increase in the volume of housing construction in the Russian Federation. The modern trends in the field of energy and resource saving determine the need of the use of efficient building materials that ensure the safety, comfort and minimum cost of housing construction. Among the materials, often used for erecting of fencing structures, it is possible to note effective small-piece elements (ceramic and light-weight concrete units, etc.). To ensure the solidity of such structures, it is necessary to use the masonry mortars whose properties correspond to those of the main wall material. The existing dry mixes for obtaining of such mortars are expensive and often do not meet the minimum physical-and-mechanical and exploitation requirements. The solution of this problem is the usage of the hollow ceramics (aluminosilicate) microspheres as a filler for such mixes. The article presents the results of studies of the main physical-and-mechanical and exploitation characteristics of dry masonry mixes with hollow ceramics microspheres modified with various chemical additives. The effect of the compounding factors on the average density and strength of dry masonry mixes was studied. The compositions have been optimized by the methods of mathematical planning.

THE PROPERTIES OF MOTHER LIQUORS OF THE WATER-SOLUBLE SALTS PRODUCTION BY CONVERSION METHOD

The paper deals with the conversion method which leads to the formation of mother liquors as by-products. In some cases, they can be used as commodity products after pre-revision. However, optimization of physical and chemical, and the functional properties of the liquid mixes by empirical way can appear long and inefficient process. The paper employs the physical and chemical analysis of homogeneous systems and a method of mathematical planning of experiment that allows optimizing the liquid mixes both on composition, and on some set functional properties. The paper notes the conversion method of production of potassium nitrate from calcium nitrate and potassium chloride is covered by a number of patents, however, it is not realized in industrial scale so far. The reason for this may be a problem of further use of the mother liquors containing calcium and potassium chlorides and nitrates. In the majority of patents, there are no data on the production of calcium chloride from the mother liquor that testifies to a number of the difficulties connected to crystallization of this salt. The mother liquors of potassium nitrate production can be used as an anti-icing reagent, a coolant, the heat-carrier in power systems, a mineral fertilizer and the heavy liquids in a petroleum industry. However, in each specific case, the certain revision of their composition is required in order to achieve the necessary physical and chemical, and functional properties. The paper analyzes the possibility for using the mother solution in the potassium nitrate production as heavy liquids in the oil industry. Moreover, the paper studies the cuts of the systems CaCl 2 – Ca(NO 3 ) 2 – М – H 2 O where М is the mother solution after the crystallization of potassium nitrate. The density and temperature of the solution freezing are identified in the homogeneous areas of the cuts. It is shown a fundamental possibility for improving the operating characteristics of the mother solutions with the introduction of additional amounts of calcium salts.

Исследование клеверотерки-скарификатора КС-0,2 с декой овального типа при скарификации семян

In 2017 in the Kirov region the clover-grater-and-scarificator KS-0.2 intended for extraction of seeds from wad of clover and other legumes and grasses as well as scarification of hard legume seeds was investigated. The machine includes frame, body, drum, deck, batch hopper, tedder, device for supplying material to a machine, pipe for input and output, extension, holder for bag, the drive mechanisms, electric equipment. For exception of the operation for deck replacement when reconfiguring the machine it was experimentally investigated the process of scarification of seeds of Galega orientalis with the oval type deck, equipped with 7 steel scarification plates installed between the round bars. Using of methods of mathematical planning of the experiment studied allow to established the influence of constructive and technological parameters on the degree of scarification of seeds and crushing of the seeds. Determined the range of values of the studied parameters under which the observed agro technical requirements for the machine were met. As a result of research defined values are revealed of the constructive and technological parameters of the machine for extraction and scarification grass seed КБ-0.2 with the use of a oval type deck, providing the required quality parameters (degree of scarification of seeds higher than 95% and crushing of seeds less than 1.5%): frequency of rotation of the drum 850...950 min -1 ; productivity 0.2...0.3 t/h; clearances at the entrance - 6.0 mm, at the outlet - 3.0 mm.

SELECTION OF STRUCTURES OF THE ACTIVATED MINERAL POWDERS WITH USE OF A METHOD OF PLANNING OF EXPERIMENT

With use of a method of mathematical planning of experiment structures are picked up and mathematical models of properties of the activated mineral powders on the basis of ashes-ablation depending on the expense of activating additives are received. Optimum structures and properties of the activated mineral powders on the basis of the ashes-ablation, corresponding to requirements of GOST 32761-2014 to the activated mineral powders of mark of MP-1, are established by means of software package Maple. Mathematical planning of experiment has allowed to reduce considerably process of selection and to optimise structures of the activated mineral powders with the set complex of properties.

Developing compositions based on nanoparticles for final treatment of textile materials

The study is aimed at developing a stable composition based on nanodimensional silicon dioxide, which may be used for final treatment of cotton and polyester textile materials in the processes of industrial and household washing of textile products in order to improve their properties (hydroscopicity, moisture yielding capacity, moisture absorption, humidity, water vapor permeability and soiling). As a result of the performed studies, four compositions based on nanodimensional silicon dioxide were formed. The main advantages of the developed compositions are: a significant increase in indices of the properties of textile materials with different fiber composition after treatment; all the experiments were conducted at room temperature and low module processing, which indicates energy efficiency while using the developed compositions. Stabilizing properties of surfactants and polymers were revealed, the expediency of their joint use with the purpose of increasing the sedimentation and aggregation stability of the suspensions based on silicon dioxide was substantiated. Applying the methods of mathematical planning with the use of simplex centroid plan for q=3, compiled with relation to pseudo­components, allowed assessing the changes in properties in a limited area of composition components content: polymer from 0 g/l to 10 g/l, SAS from 0 g/l to 5 g/l, nanodimensional silicon dioxide of less than 10 g/l. We managed to optimize the ratio between components of the compositions using the Harrington function of desirability for maximum enhancement of properties of hydroscopicity, moisture yielding capacity, moisture absorption, water vapor permeability, humidity and soiling of the studied textile materials. The assessment of sedimentation and aggregation resistance of the developed composition formulations was carried out and the compositions were obtained, the percentage content of nanoparticles in fractions in relation to the initial content of nanoparticles increases. In the bicomponent suspension, 17.1 % of nanoparticles remain in the solution, and with adding a mixture of stabilizers their amount increases by 11.5 % for composition No. 1, by 17,1 % for composition No. 2, by 16.5 % for composition No. 3, and by 6,24 % for composition No. 4. These results indicate the existence of features of monodispersity of compositions based on nanodimensional silicon dioxide. Characteristics of the compositions change by 1–3 % as a result of their redispersion after stilling for 30 days. Negative impact of using compositions on the environment was studied by analyzing the waste solution as for the amount of surfactants. It was found that more than half of silicon dioxide remains in the waste solution. The solution to the problem of avoiding the above mentioned negative phenomena by reusing sediment was formulated. However, no specific conclusions regarding the recommendation of one of the four studied compositions were made. The results of the research may be implemented in the production of textile materials. The composition may be used as a preparation for the final treatment of textile materials with the aim of improving their marketing prospects and consumer properties. It is possible to use the developed compositions at enterprises of household services (laundries) and for individual home washing. In these cases, the use of the composition as a conditioner for rinsing is implied.

Physical and Mechanical Properties of the Cement Stone Based on Biocidal Portland Cement with Active Mineral Additive

The article considers innovative materials for construction. Using mathematical planning methods, we studied how the quantitative composition, the biocidal additive and gypsum content influence on the compressive and flexural strength and density of the composites. We found that the more gypsum in a composition the higher compressive and flexural strength of a specimen. So, with the greatest degree of compositions filling (fly ash – 20 mass fractions, gypsum – 11.2 mass fractions) maximum compressive strength is 72.5 MPa. We determined when the fly ash content rises up to 20 mass fractions per 100 mass fractions of clinker, flexural strength rises too and specimen density decreases. The developed compositions of biocidal cements recommended for use in the manufacture of materials, products and structures for buildings and constructions, operating in aggressive environments.