Fear of Missing Out (FoMO) is one of the risk factors for problematic mobile phone use (PMPU) among adolescents. However, previous findings have been inconsistent and have not comprehensively considered the roles of cognition and emotion. Grounded in the I-PACE model, this study examines the role of desire thinking and craving in the predictive relationship between FoMO and PMPU among adolescents through path analysis, while employing network analysis to identify the most central and influential nodes within this mechanism. This study focused on adolescents and employed the FoMO scale, the Desire Thinking Questionnaire, the Psychological Craving Assessment Scale, and the Smartphone Application-Based Addiction Scale to conduct a four-wave longitudinal survey of 509 adolescents. The results of the path model showed that desire thinking and craving played a role of chain mediation in this relationship. Network analysis revealed that the "irresistible longing" node was the strongest bridge node of the network. Among the associations between nodes of different communities, the strongest association was between the "difficulty stopping" node in Desire Thinking and the "irresistible longing" node in Craving, followed by the "stress relief" node in Craving and the "mood modification" node in PMPU. These findings provide empirical evidence for the I-PACE model and underscore the critical roles of desire thinking and craving. They also offer valuable insights for future research and clinical interventions targeting PMPU among adolescents.

Sequential associations among perceived heat-related symptoms, fatigue, and performance-related behavior during summer training.

The relationship between mental health disorders and LUTS.

Central serous chorioretinopathy (CSC) is a chorioretinal disease characterised by serous subretinal fluid (SRF) in the macula, resulting in sudden central vision loss. It predominantly affects working-age adults, particularly men aged 30 to 60 years. Its multifactorial pathophysiology is modulated by systemic factors, such as corticosteroid use, psychological stress, and hypertension. Previous studies suggest that broader environmental influences, including seasonal variation, may contribute to disease onset. This study aimed to systematically review and analyse the evidence on seasonal variation in CSC incidence. A systematic search was conducted across 10 databases (PubMed, Embase, Cochrane Central, Web of Science Core Collection, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI-Korean Journal Database, ProQuest™ Dissertations and Theses Citation Index, and SciELO Citation Index) on 22 June 2025. Eligible studies included observational designs reporting CSC incidence or frequency across seasons; case reports and reviews were excluded. Five studies, with 907 participants in total, met the inclusion criteria. Three studies with sufficient data were included in quantitative meta-analysis, while the remaining two conference abstracts were included in the qualitative synthesis. Seasonal variation in CSC incidence was reported across studies. Meta-analysis using summer as the reference season showed a significantly increased incidence of CSC in spring (OR 1.42; 95% CI: 1.18-1.73; p = 0.0003) and autumn (OR 1.23; 95% CI: 1.02-1.48; p = 0.03). No significant difference was found for winter (OR 0.97; 95% CI: 0.80-1.19; p = 0.80). The remaining 2 studies not included in the meta-analysis also reported seasonal trends consistent with these findings. The findings indicate a significant seasonal variation in CSC incidence, with a consistently increased risk during spring and autumn compared with summer. Further research is needed to examine how seasonal environmental and physiological mechanisms may contribute to CSC development.

Physio-Cognitive Decline Syndrome (PCDS) is a clinical characterized by concurrent declines in physical and cognitive functions that precede disability. Taiwan's rapidly aging population highlights declines in physical and cognitive functions as precursors to disability, posing key challenges in geriatric care. Research shows these declines begin in early middle age and progress with age. Understanding middle-aged and older adults' experiences and coping strategies for Physio-Cognitive Decline Syndrome (PCDS) is essential for developing effective interventions. This study explored the subjective experiences and perceptions of PCDS among middle-aged and older adults to identify key themes and coping strategies in response to such declines. This qualitative study utilized purposive sampling, semi-structured face-to-face interviews with middle-aged (55-64 years) and older (≥65 years) adults to explore PCDS perceptions. Data were analyzed using content analysis. Participant experiences and perceptions formed three themes: (1) aging accelerates PCDS progression, (2) PCDS threatening daily life, and (3) adapting to changes. These findings further delineate a four-phase PCDS process: Individual Perception (recognizing decline), Life Threat (impact on daily life), Adaptation (accepting reality), and Positive Coping (implementing management strategies). Correspondingly, participants developed coping strategies to mitigate physical and cognitive decline, seek professional assessment, and strengthen support systems. Middle-aged and older adults with PCDS face physical and cognitive declines, mobility limitations, psychological stress, and social isolation. They adopt coping strategies like health maintenance, cognitive training, and social participation. Family and social support systems play a crucial role in their coping processes, while seeking professional medical assistance and engaging in community activities further enhance their confidence in managing PCDS.

Spinal cord injury (SCI) is a debilitating neurological condition that leads to physical dependence, substantial financial burden, and psychological stress. Current for SCI, such as stem cell therapy, pharmacological interventions, and neural implants offer limited functional recovery. Among emerging strategies, exosome-based therapies in nerve damage can reduce neuroinflammation and promote neural repair by angiogenesis and neurogenesis. MicroRNAs (miRNAs) are key modulators of inflammatory and regenerative pathways in SCI. Specifically, miR-19a-3p, miR-19b-3p, and miR-27b have been implicated in regulating neuroinflammatory responses, neuronal survival, and tissue remodeling. Dysregulation of these miRNAs following SCI can exacerbate inflammation and hinder recovery. In this study, exosomes were extracted and characterized using flowcytometry for surface markers CD81 and CD9, scanning electron microscopy (SEM), dynamic light scattering (DLS), and Zeta potential analysis. Thirty-two female rats were randomly assigned into four groups: laminectomy only, contusion, contusion + PBS, and contusion + exosomes. SCI were induced using contusion model and thirty minutes after the injury, the exosome-treated group received an intravenous injection of 100 μl of exosomes via the tail vein for 7 days. Motor and behavioral functions were assessed through the open-field test, Basso, Beattie, and Bresnahan (BBB) scale and narrow beam test (NBT). Eight weeks after the SCI, real time PCR, Western blotting was utilized to assess changes in inflammatory cytokines, while histological changes were observed using hematoxylin and eosin (H&E) staining and stereology. In vivo experiments showed that the administration of exosomes significantly enhanced functional recovery and behavioral test outcomes following SCI. The treatment also resulted in a significant reduction in inflammatory cytokine levels and a marked decrease in the size of the cavity in the group treated with exosomes. Molecular analysis revealed that exosome therapy modulated the expression of miR-19a-3p, miR-19b-3p, and miR-27b, which are key regulators of neuroinflammation and neural repair. These findings suggest that exosomes hold strong therapeutic potential for treating SCI by modulating inflammation and promoting neural repair. Collectively, these findings indicate a potential mechanism through which exosomes exert their neuroprotective effects, particularly by regulating inflammatory and regenerative pathways.

The correlation between gut microbiota and sleep quality changes in breast cancer patients receiving postoperative chemotherapy: a longitudinal study.

The role of housing in patient health: Practitioner insights and protocol review.

Research on mental fatigue in ball sports (2000-2025): A bibliometric analysis.

Displacement in the body: A mixed-methods study of the syndemic interaction of mental distress and musculoskeletal disorders among Afghan immigrants.

Social comparison and envy are significant psychosocial stressors in humans and are known to be involved in the onset and persistence of psychiatric disorders. However, animal models capable of experimentally reproducing the effects of indirect social comparison without physical contact are limited. In this study, we used a newly developed "adjacent-cage paradigm" to investigate whether chronic vicarious exposure to conspecifics in different environments induces envy-like stress in mice. Male C57BL/6 N mice served as observers, while demonstrator mice were assigned to one of four conditions: (1) an environment enriched with objects, (2) an igloo, (3) a tube, or (4) social isolation. Observers were continuously exposed to these adjacent cages for 21 days. Subsequently, a comprehensive battery of behavioral tests was conducted to assess general health, anxiety-like behavior, spatial memory, social behavior, and depression-like behavior. In the objects condition, a decrease in time spent in the light compartment of the light/dark box indicated an increase in anxiety-like behavior. In the isolation condition, the mean duration per social interaction was shortened, suggesting a qualitative change in social behavior. The igloo condition resulted in reduced immobility time in the forced swim test, suggesting a possible alteration in stress coping behavior. Furthermore, increased nociceptive sensitivity was observed in the hot plate test under both the objects and isolation conditions. Although the envy-like stress paradigm did not affect many behavioral indices, it did cause condition-dependent and limited behavioral changes. This suggests that the paradigm may serve as a novel model for capturing psychological and context-dependent social stress, which differs from conventional physical stress models. Elucidating the neural basis of this paradigm is expected to contribute to the understanding of how social comparison affects mental health in modern society.

Understanding national trends and regional variations in mental health disorders among older adults is essential for improving mental health services and guiding evidence-based policy. This study examined national and regional trends in major mental health disorders, including anxiety (ANXD), trauma and stressor (TSRD), bipolar (BIPD), depressive (DEPD), and schizophrenia or other psychotic (SOPD) disorders, among U.S. older adults (≥60years) treated in the State Mental Health System. Ten years (2013-2022) of Mental Health Client-Level Data were analyzed for 4,195,615U.S. adults. Unadjusted and adjusted logistic regression models, controlling for age, sex, and race/ethnicity, were used to assess temporal trends in each disorder nationally and by U.S. Census region. Nationally, ANXD and TSRD showed increasing trends, with ANXD prevalence rising from 13.29% to 22.62% (adjusted odds ratio (AOR): 1.90, 95% CI: 1.26-2.88) and TSRD from 8.73% to 14.30% (AOR: 1.70, CI: 1.30-2.23). In contrast, BIPD (17.03% to 14.23%; AOR: 0.79, CI: 0.68-0.92) and SCOD (27.19% to 24.29%; AOR: 0.78, CI: 0.70-0.87) declined. Regional variations were pronounced: the Midwest and South showed steep increases in ANXD and TSRD; the Northeast exhibited rising TSRD; and in the West, ANXD and TSRD rose while BIPD and DEPD declined. Anxiety and trauma-related disorders increased nationally and across most regions, whereas bipolar and psychotic disorders declined, with depressive disorders remaining persistently prevalent. These patterns highlight the need to investigate underlying drivers such as diagnostic, demographic, and service-related factors and to develop targeted interventions for each disorder.

A wearable system enabling acute stress monitoring and closed-loop mitigation through transcutaneous median nerve stimulation.

Moderating effect of coping strategies on the relationship between mental workload and work stress. The case of financial traders. A structural modeling approach

Burnout, Stress, and Moral Injury Among Emergency Medical Services Clinicians: A Systematic Review.

A mixed methods feasibility and acceptability study to test a brief nature-based intervention to improve university students’ mental wellbeing

Physiological responses to emotional video stimuli: ECG, EDA, and temperature data.

Food insecurity and depressive symptoms among miners in Ghana: The role of psychosomatic factors

Geopolitical rhetoric as a potential psychological stressor: A conceptual review of mechanisms linking political discourse and population mental health.

Cerium-iron symbiotic nanozyme alleviates drought stress in wheat by targeting stomatal regulation and photosynthesis.