Higher physical activity is associated with reduced odds of depressive symptoms among university students: A meta-analysis of over 66,000 participants.

Temporomandibular disorders (TMD) and orofacial pain (OFP) are influenced by behavioural and psychosocial stressors. The Gaza Strip's prolonged conflict provides a critical context for estimating burden and correlates. To estimate the prevalence of self-reported TMD/OFP symptoms and identify independent risk factors among adults in Gaza during wartime. Cross-sectional survey of 1000 adults (500 women, 500 men) equally allocated across five governorates. A structured questionnaire captured self-reported facial/TMJ/ear pain, jaw function, parafunctional behaviours (e.g., bruxism, oral habits) and psychological symptoms (tension, mood, sleep) was used. Analyses used descriptive statistics, chi-square tests and multivariable logistic regression adjusted for sex. TMD-related pain was reported by 33.1% (n = 331). Neck pain occurred in 41.0% and morning facial stiffness in 28.2%. In bivariate analyses, men more often reported jaw dysfunction (limited opening, chewing difficulty, joint sounds), while women more often reported psychological symptoms; sex was not an independent predictor. Independent predictors were morning facial stiffness (AOR 2.57-5.27 across frequency categories), limited mouth opening (AOR 3.03; 95% CI 1.75-5.28), joint noises (AOR 3.13; 95% CI 2.08-4.72), sleep bruxism (AOR 2.33; 95% CI 1.51-3.60) and daily somatic pain elsewhere (AOR 2.99; 95% CI 1.53-5.84). Gum chewing showed an inverse association (AOR 0.62-0.31). Tension, sadness, global sleep disturbance, daytime bruxism, smoking, alcohol use, orthodontic history and governorate were not independent predictors. The multivariable model showed good performance (AUC = 0.882; Nagelkerke's R2 = 0.519). During active war, self-reported TMD and OFP symptoms are prevalent among adults in Gaza and are strongly associated with parafunctional habits and psychological distress, both potentially intensified by war-related stress. These findings underscore the need for integrated dental and mental health interventions in conflict-affected populations.

Predictors of momentary emotion differentiation among veterans in residential treatment for posttraumatic stress disorder: An ecological momentary assessment study.

Fractional-order safe mental-health corridor modelling with Matignon spectral analysis of post-pandemic fatigue-to-recovery dynamics.

School personnel have historically exhibited universal practices, where assumptions of "one-size-fits-all" prevail. The limitations of this approach are evident when school personnel attempt to apply universal practices to students from underrepresented and historically marginalized populations. In this article, we describe the Participatory Culture-Specific Intervention Model (PCSIM; Nastasi & Hitchcock, 2016; Nastasi et al., 2004), a 10-phase process for developing culturally responsive practices. PCSIM uses an interdisciplinary approach to program development for social and cultural change, with an emphasis on participation and the intersection of culture and context. This article presents four examples of mental health prevention and intervention projects that used PCSIM in schools and communities to address issues of equity for this group, including urban African American students, lesbian, gay, bisexual, transgender, queer/questioning, and other sexual and gender identities youth, and individuals with developmental disabilities. This article concludes with lessons learned and suggestions for practitioners and researchers when applying PCSIM to address issues of equity for these groups through collaborative program development, implementation, and evaluation. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Suicidality calls to a national helpline: One year post the October 7 terror attack and amidst a prolonged war.

Decoding workplace mental health: Automatic clustering of the Spanish workforce.

Generalized Anxiety Disorder (GAD) is prevalent and often co-occurs with depression, contributing to significant disability and healthcare burden. Although treatments such as CBT and SSRIs are effective, access remains limited. This exploratory, randomized controlled trial evaluated the effectiveness of an AI-powered mental health app (PATH) in reducing symptoms of anxiety and depression. A total of 316 UK-based participants (aged 19-70) were randomized to either the intervention group (PATH) or a control group (NHS self-help website). The intervention provided evidence-based strategies including CBT-informed chat therapy and interactive tools. Anxiety (GAD-7) and depression (PHQ-9) scores were measured at baseline, two, eight, and twelve weeks. Of the 316 randomized participants, 235 completed the post-intervention assessment (33.0% attrition in the intervention group vs. 18.5% in the control group). Retention at 8-week and 12-week follow-ups was 77.4% and 54.0%, respectively. At two weeks, the intervention group showed significantly lower GAD-7 and PHQ-9 scores compared to control, with medium effect sizes. At eight weeks, those who continued using the app showed significant reductions in both anxiety and depression, while those who discontinued still showed medium improvements in anxiety. Effects were maintained at twelve weeks, with moderate to large effect sizes. Findings suggest that PATH significantly reduces anxiety and depressive symptoms, particularly with continued use. These results support the app's potential as a scalable, accessible digital intervention to address mental health treatment gaps.

Genomic medicine is transforming psychiatry by revealing the genetic aetiology of mental illness. The diversity of India’s population presents a singular opportunity to incorporate genomic information into psychiatric practice. This review discusses recent developments in psychiatric genomics, such as Genome-Wide Association Studies (GWAS), Polygenic Risk Scores (PRS), and pharmacogenomics, which facilitate more tailored mental health interventions. Pharmacogenomics promises to individualise treatments based on genetic profiles, whereas epigenetics and gene-environment interactions shed light on the biological underpinnings of mental health across various sociocultural settings. Genomic psychiatry in India has the potential to be applied in personalised medicine, early risk prediction, targeted therapies, and informing national mental health policy. Yet, the uptake of genomic psychiatry is hindered by infrastructure constraints, ethical as well as privacy issues, and the requirement of cultural competence. The proposed directions include increased research, combining genomic Learning Health Systems (gLHS), and use of Artificial Intelligence (AI) in predictive analytics. This review sums up with major recommendations for progressing genomic psychiatry in India through modifications in policy, funding for research, and public education efforts.

Navigating national acute trauma: Developing and implementing a crisis mental health service for evacuated civilians following the October 7, 2023, attack in Israel.

Best-Practice Mental Health Interventions Following Acute Cardiovascular Events.

Understanding whether living alone correlates with depression and suicidal ideation is key to identifying older adults at risk. We pooled data from the 2005, 2010, 2017, and 2021 nationally representative cross-sectional Health Barometer surveys conducted by Santé Publique France, and focused on adults aged 65 to 75 (n=12,026). Logistic regressions were performed to identify associations between 12-month major depressive episode (MDE), suicidal ideation (SI) and living alone, adjusting for sociodemographic factors. Analyses were conducted in the overall sample and stratified by sex. Overall, 18.3% of men and 33.8% of women lived alone. In total, 5.5% of adults experienced MDE: 8.8% of those living alone and 4.3% of those not living alone (χ2=80.94, df=1, p<.001), and 2.9% reported SI: 4.8% of those living alone and 2.1% of those not living alone (χ2=55.60, df=1, p<.001). In the overall sample and controlling for sociodemographic factors, living alone was associated with MDE (AOR=1.80, 95%CI=1.51-2.14). This held true both among men (AOR=2.30, 95%CI=1.60-3.32) and among women (AOR=1.69, 95%CI=1.38-2.06). Controlling for sociodemographic factors and MDE, living alone was associated with 12-month SI (AOR=1.90, 95%CI=1.49-2.44). This was true in men (AOR=2.21, 95%CI=1.46-3.34) and in women (AOR=1.68, 95%CI=1.24-2.29). Cross-sectional survey preventing causal interpretation. In the first ten years following typical retirement age, men and women living alone deserve attention from public health officials and clinicians as they, as a group, have a higher risk of MDE and SI, highlighting the need for targeted mental health interventions and social support strategies.

Seven-year data trends in mental health of refugees in transit: a repeated cross-sectional study.

Digital mental health interventions (DMHIs) have shown promise improving depression, anxiety, and psychiatric distress, yet real-world engagement remains low. Increasing engagement has great potential to improve the impact of DMHIs, but little is known about the drivers of engagement in naturalistic settings. To better understand predictors of engagement, we examined sociodemographic and clinical characteristics associated with DMHI usage among a large clinical sample of adults. 1223 adults (74% White, 68% women, Mage=36.8years) with scheduled intake appointments for outpatient psychiatric services were randomized to either a mindfulness-based app (Headspace) or a CBT-based app (SilverCloud). Usage data were automatically collected, and participants were neither required nor compensated to use the apps. Participants engaged with their assigned DMHIs a median of 8days, with 88.2% of participants using their assigned DMHI at least once. Participants engaged with Headspace for more than twice as many days [IRR (95% CI)=2.4 (2.1, 2.7)] as SilverCloud. Female sex, white race, a college degree, and older age up to 60 predicted greater engagement. Further, depression severity was associated with engagement in a non-linear manner for those assigned to Headspace, with less engagement at minimal/mild and severe symptoms compared to moderate and moderately-severe symptoms. These findings indicate meaningful differences in engagement between DMHIs based on sociodemographic and clinical characteristics. There may be opportunities to improve engagement by tailoring DMHI offerings, with a particular emphasis on meeting the needs of less-engaged populations.

Grounded in Self-Determination Theory and Social Cognitive Theory, this longitudinal study examined reciprocal relationships among MVPA, academic self-efficacy (ASE), self-esteem, and depression in 640 Chinese junior high school students (Mage=13.26, SD=0.76). Validated measures were administered at two time points over six months. Results showed significant autoregressive effects and key cross-lagged paths: higher self-esteem at Time 1 predicted lower depression at Time 2, while higher depression at Time 1 negatively predicted MVPA at Time 2. However, MVPA at Time 1 did not significantly predict later depression. These findings suggest that internal beliefs and psychological needs do not function in isolation. Enhancing adolescents' competence (ASE) and confidence (self-esteem) may be essential for improving mental health. This study offers theoretical and practical implications for school-based interventions integrating physical activity and psychological development. EDUCATIONAL RELEVANCE STATEMENT: This study provided longitudinal insights into the psychological and behavioral factors influencing junior high school students' well-being. The findings showed that earlier depressive symptoms significantly predicted lower levels of physical activity six months later. Academic self-efficacy and self-esteem demonstrated strong temporal stability, while self-esteem-but not academic self-efficacy-significantly predicted reduced depressive symptoms over time. These results emphasized the need for early mental health interventions in school settings and suggested that promoting self-esteem may serve as a more effective approach to prevent adolescent depression than focusing solely on academic self-beliefs.

The mass civilian attack on October 7th, 2023, marked a watershed moment in Israeli history, particularly for frontline communities such as Sderot. This paper presents an in-depth descriptive analysis of the response provided by the Sderot Resilience Center (SRC), a community-based mental health facility established in 2007 to address chronic exposure to security-related trauma based on over 13,000 electronically documented treatment records, this study documents a dramatic surge in service demand following the events of October 7th, identifies demographic and treatment-related shifts-including a marked increase in adult service utilization and a relative decline among children and adolescents-and reflects on the unique therapeutic model employed by resilience centers in Israel. Beyond the clinical response, the SRC exemplifies an innovative community-based governance model that integrates mental health, welfare, education, and community services under a unified resilience framework. Operated independently but closely collaborating with the municipality, the SRC's longstanding presence within Sderot fostered trust and accessibility, allowing residents to view it as a familiar, reliable resource rather than an external intervention. This foundation of trust, combined with the center's capacity to rapidly scale interventions and adapt to evolving needs, formed the basis of its success in responding to the crisis. Findings demonstrate that such centers can rapidly scale mental health interventions and adapt to evolving needs in times of national crisis.

The lingering shadow: Understanding the long-term impact of natural disasters on social trust.

Unmet Mental Health Need and Barriers to Care Among Transgender and Cisgender Adults.

Distinct patterns of formal treatment and informal support strategies among U.S. college students with elevated symptoms of depression and/or anxiety: A cluster analysis.

From a neurobiological standpoint, emotion regulation is a core neurocognitive process that supports psychological well-being and adaptive social functioning through coordinated interactions between cortical regulatory systems and subcortical affective circuits. Among regulation strategies, expressive suppression—the inhibition of outward emotional expression after an emotional response has already been initiated—has received increasing attention in affective neuroscience. Suppression is associated with top-down inhibitory control processes mediated by the dorsolateral prefrontal cortex and ventrolateral prefrontal cortex, which modulate activity in limbic regions including the amygdala and insula that encode emotional salience and interoceptive states. Although suppression may facilitate short-term social coordination, frequent reliance on this strategy has been associated with increased physiological stress and elevated risk for anxiety and depressive symptoms. Neuroimaging and psychophysiological evidence suggest that suppression engages sustained activation of the anterior cingulate cortex and other cognitive control networks, reflecting the metabolic and cognitive demands of inhibiting behavioral expression while affective responses persist. These processes are further influenced by neuromodulatory systems involving serotonin, dopamine, and gamma-aminobutyric acid, which regulate emotional reactivity and inhibitory control. This study examines the neural architecture underlying expressive suppression using publicly available functional magnetic resonance imaging (fMRI) data from the OpenNeuro dataset ds000108, which investigates prefrontal–subcortical pathways involved in emotion regulation tasks. The dataset includes 34 participants performing cognitive emotion regulation tasks involving negative image appraisal. Analysis focuses on functional activation patterns within prefrontal–limbic circuits implicated in emotional control. Results indicate that suppression and related regulatory processes recruit top-down inhibitory control networks involving the dorsolateral prefrontal cortex and ventrolateral prefrontal cortex, which modulate activity in limbic structures such as the amygdala and insula. These interactions reflect dynamic prefrontal–subcortical pathways that influence emotional experience and behavioral expression. Neurochemical modulation via serotonin, dopamine, and gamma-aminobutyric acid likely contributes to variability in regulatory outcomes. Findings highlight how sustained recruitment of executive control networks during suppression may increase cognitive load and stress, while adaptive emotion regulation strategies rely on flexible engagement of distributed neural networks. These results support integrative models linking neural circuitry, culture, and psychological outcomes in emotion regulation. In turn, cultural context may shape the neural implementation and functional outcomes of suppression. In collectivist cultural environments, norms emphasizing emotional restraint may reinforce neural pathways associated with social monitoring and cognitive control, including circuits involving the medial prefrontal cortex. Conversely, individualistic cultures tend to prioritize expressive authenticity, promoting regulatory strategies such as cognitive reappraisal that engage earlier modulation of limbic responses. This paper synthesizes empirical findings from affective neuroscience and cultural psychology to examine the neural mechanisms, mental health correlates, and sociocultural modulation of expressive suppression. Particular attention is given to bicultural stress and identity conflict, which may increase reliance on suppression among individuals navigating multiple cultural frameworks. We conclude by discussing implications for culturally informed neuroscience and mental health interventions, emphasizing the importance of regulatory flexibility in the adaptive engagement of prefrontal–limbic networks.