Revisiting the effects of physical activity on anxiety and mediation from plasma proteins: triangulation of evidence from observational study, Mendelian randomization, mediation and meta-analysis.

Association between age at first birth and depressive symptoms: the mediation effects of HDL-cholesterol.

Systemic inflammation mediated the association between body roundness index and depression among adults: a nationwide population-based study.

Body roundness index, depression, and the mediating role of lifestyle: Insights from the UK biobank cohort.

Exploring the causal relationships between psychiatric disorders and hypothyroidism combining mendelian randomization with network pharmacology.

ABSTRACT In the competitive landscape of the job market, imaginative thinking allows adolescents to see beyond traditional career paths and envision creative ways to solve problems. Moreover, competitive attitude drives success in the workplace is not necessarily about outperforming others, but about striving for personal growth. We sought to analyze in a sample of 661 Italian adolescents, 424 males and 237 females, the role of imaginative and competitive attitudes and self-efficacy as possible predictor variables of career self-efficacy in adolescents. Results indicated that imaginative capability was positively associated with both competitive attitude and problem-solving self-efficacy. Additionally, both problem-solving self-efficacy and competitive attitude showed direct positive relationships with career decision self-efficacy. Mediation analyses revealed that competitive attitude and problem-solving self-efficacy jointly mediated the link between imaginative capability and career decision self-efficacy. Overall, imagination appears essential for anticipating future possibilities, while problem-solving competence emerges as a key resource for navigating evolving professional landscape.

Purpose This study draws on value congruence theory and epistemic motivation theory to examine whether the effect of ethical and environmental appeals on consumers’ perceptions of technological improvement and support for government initiatives varies across different novel food technologies, including cellular agriculture, gene editing and controlled environment agriculture. It further investigates whether epistemic value acts as a psychological mechanism that mediates these effects. Design/methodology/approach A 3 (appeal: ethical, environmental and control) × 3 (food technology: cellular agriculture, gene editing and controlled environment agriculture) between-subjects experimental design was employed to assess the effectiveness of strategic communication in enhancing consumer perceptions. Mediation analyses tested whether epistemic value explains the relationship between these relationships. Findings Based on data from 1,360 New Zealand consumers, ethical and environmental appeals increased support for cellular agriculture but not for gene editing or controlled environment agriculture, likely due to differences in how consumers perceive these technologies relative to the message appeals. Additionally, epistemic value emerged as a key psychological mechanism that helps explain these differential effects. Originality/value This study highlights the importance of aligning message appeals with consumers’ perceptions of novel food technologies. It provides both theoretical and practical insights for improving public support for novel food technologies through more targeted and aligned communication strategies.

Genetic correlates of self-harm hospitalization: Insights from polygenic scores in the Taiwan Biobank.

Predictive value of a body shape index for incident type 2 diabetes and all-cause mortality in adults: Evidence from two long-term cohort studies.

The role of motor subtypes in modulating neuropsychiatric and cognitive function in Parkinson's disease: A group-stratified mediation analysis.

Depressive symptoms, balance, and gait in older adults: Mediation and moderation analysis.

Associations of indoor airborne microbiome with systemic inflammation in the context of indoor particulate matter pollution and the metabolic mechanisms.

The association of social determinants of health and depressive symptoms with quality of life among rural patients with coronary heart disease and heart failure.

This paper aims to evaluate the role of AI and ML-driven innovative technologies in enhancing customs operations in Jordan. This research employed a quantitative approach to develop an overall conceptual model that encompasses both the technical and behavioral aspects of intelligent system adoption. The target population consisted of customs officers, border security personnel, and IT personnel responsible for customs clearance and trade facilitation in Jordan. The structured questionnaires were administered to the respondents to measure their perceptions of system effectiveness, satisfaction, performance outcomes, and evasion behavior and yielded a total of 358 valid responses. The research was conducted with proper statistical analysis, and the statistical techniques employed included primary data collected via SPSS Version 29 and advanced modeling using Structural Equation Modeling-Partial Least Squares (SEM-PLS) through the use of SmartPLS 4.0. The results indicated that the measurement model proved to be both valid and reliable, with Cronbach's alpha values exceeding 0.82 and AVE values above 0.50, indicating good internal consistency and convergent validity. Moreover, the structural model achieved good explanatory power, with R² values of 59% for Customs Evasion, 43% for User Satisfaction, and 100% for Digital Performance Indicators. These findings underscore the significance of user satisfaction as a key outcome of system effectiveness and a valuable tool for enhancing performance and deterrence. More specifically, the results shown how Intelligent System Effectiveness presents a positive and significant impact on User Satisfaction (β = 0.656, p < 0.001), which in turn has a high positive effect on both Digital Performance Indicators (β = 1.000, p < 0.001) and Customs Evasion reduction (β = 0.770, p < 0.001). The mediation analysis also confirmed that User Satisfaction fully mediates the relationship between system effectiveness and performance outcome, as well as between system effectiveness and evasion reduction. This research contributes to theory and practice by demystifying the design and implementation of AI-driven customs systems. It illustrates the importance of valuing both technical system quality and user-centric values in achieving and maintaining optimal performance in the digital space, as well as conformance with the law.

Associations between emerging endocrine-disrupting chemicals and thyroid hormone homeostasis in pregnant women.

Automation or augmentation? The impact of artificial intelligence's technological characteristics on usage intention in medical staff.

Antibiotic consumption, genetic risk and incidence of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.

Immune cells influence major depression through metabolites: A Mendelian randomization analysis of bidirectional causality and mediating effects.

Interoceptive sensibility mediates emotional dysregulation: Insights from individuals with Bipolar II Depression.

The complexity of twenty-first century church leadership calls for adaptive models that move beyond the dominance of a single pastoral figure. This study examined the effect of collective leadership on pastoral ministry and church growth, with pastoral ministry tested as a mediating variable. The research was conducted at the Gereja Kristen Perjanjian Baru (GKPB) “Masa Depan Cerah” in Surabaya, Indonesia, involving 100 valid respondents drawn from both leaders and active members. Data were gathered through a structured Likert-scale questionnaire and analysed using linear regression and mediation analysis. The results indicated that collective leadership had a positive and significant influence on pastoral ministry (R² = 0.514). Furthermore, both collective leadership and pastoral ministry together explained a substantial proportion of church growth (R² = 0.706). The mediation test revealed that pastoral ministry significantly strengthened the effect of collective leadership on church growth. This suggests that leadership structures are most effective when translated into concrete pastoral practices that equip and nurture the congregation. Theologically, these findings affirm the principle of the body of Christ in Ephesians 4:11-16, which stresses the complementarity of diverse leadership gifts in building up the church. Church growth is thereby understood not merely in numerical terms, but also in spiritual maturity and congregational involvement. This study provides one of the first quantitative examinations of collective leadership within an Indonesian church context. It demonstrates that a model of collective leadership integrated with pastoral ministry can serve as a biblically grounded and contextually effective strategy for sustainable church growth, and contributes fresh insights from the Global South to current global debates on church leadership.