Medial Forebrain Bundle-lateral Hypothalamus Research Articles

A reinforcement analysis of rat hypothalamus.

ARTICLESA reinforcement analysis of rat hypothalamusDM AtrensDM AtrensPublished Online:01 Jan 1973https://doi.org/10.1152/ajplegacy.1973.224.1.62MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByEndomorphin-1 and -2 immunoreactive cells in the hypothalamus are labeled by fluoro-gold injections to the ventral tegmental area19 November 2002 | The Journal of Comparative Neurology, Vol. 454, No. 3Modelling drug kinetics with brain stimulation: Dopamine antagonists increase self-stimulationPharmacology Biochemistry and Behavior, Vol. 41, No. 3Electrical stimulation of the medial prefrontal cortex supports both ‘pure reward’ and ‘reward-escape’ behavior in ratsBrain Research, Vol. 483, No. 2Hedonic interactions of medial prefrontal cortex and nucleus reticularis gigantocellularisBrain Research, Vol. 483, No. 2Diazepam modulates lateral hypothalamic self-stimulation but not stimulation-escape in ratsBrain Research, Vol. 483, No. 2Differential effects of intracerebral microinjection of morphine on approach and escape responses induced by lateral hypothalamic stimulation in the mousePharmacology Biochemistry and Behavior, Vol. 30, No. 2Electrical self-stimulation in the medial and lateral septum as compared to the lateral hypothalamus: Differential intervention of reward and learning processes?Physiology & Behavior, Vol. 44, No. 1Effects of Drugs on Reward ProcessesDorso-ventral variation in the attenuating effect of lateral hypothalamic stimulation on the switch-off response elicited from the mesencephalic central gray areaPhysiology & Behavior, Vol. 40, No. 5Self-stimulation behavior can be elicited from various ‘aversive’ brain structuresBehavioural Brain Research, Vol. 22, No. 2Approach and escape responses to mesencephalic central gray stimulation in rats: Effects of morphine and naloxoneBehavioural Brain Research, Vol. 22, No. 1Ventral tegmental stimulation modulates centrally induced escape respondingPhysiology & Behavior, Vol. 36, No. 1Brain stimulation reward in the lateral hypothalamic medial forebrain bundle: Mapping of boundaries and homogeneityBrain Research, Vol. 274, No. 1Probable independence between the genetic determinants of approach and escape responses induced by lateral hypothalamic stimulation in the mouseBehavioral and Neural Biology, Vol. 37, No. 2Behavioral responses during approach and escape induced by hypothalamic stimulation in micePhysiology & Behavior, Vol. 27, No. 5Decours temporel des effets aversif et appetitif induits par stimulation intracerebralePhysiology & Behavior, Vol. 26, No. 6Differential aversive effects of mesencephalic central gray stimulation in two inbred strains of miceBehavioral and Neural Biology, Vol. 32, No. 1Latency to turn ICSS off and on: On time is more sensitive than off time to frequency and current variationsPhysiology & Behavior, Vol. 26, No. 1Escape and approach induced by brain stimulation:A parametric analysisBehavioural Brain Research, Vol. 2, No. 1An apparent genetic relationship between appetitive and aversive effects of lateral hypothalamic stimulation in the mousePhysiology & Behavior, Vol. 25, No. 3Escape induced by combined stimulation in medial hypothalamus and central grayPhysiology & Behavior, Vol. 24, No. 1Aversive and appetitive properties of lateral hypothalamic stimulation in miceBehavioral and Neural Biology, Vol. 27, No. 4Modulation of intracranial reward-punishment interaction by scopolaminePhysiology & Behavior, Vol. 23, No. 2Catecholaminergic and cholinergic agents and duration regulation of ICSS in the ratPharmacology Biochemistry and Behavior, Vol. 10, No. 5Evolution de la fuite et de l'approche en fonction du point de stimulation dans l'hypothalamus medianPhysiology & Behavior, Vol. 22, No. 2Rewarding and aversive properties of electrical stimulation in the dorsal and ventral regions of the lateral hypothalamus in the mouseBehavioral and Neural Biology, Vol. 25, No. 2Caractéristiques de l'autostimulation au niveau du tegmentum pontin dorsal et du cerveletPhysiology & Behavior, Vol. 19, No. 6Reward-aversion analysis of rat mesencephalonNeuroscience Letters, Vol. 6, No. 2-3Effets aversifs et appe´titifs induits par stimulation me´sence´phalique et hypothalamiqueBrain Research, Vol. 130, No. 3Cardiovascular responses and lateral hypothalamic self-stimulation: Anatomical differentiation and functional significanceBrain Research, Vol. 129, No. 1Neuropharmacology of Reward and PunishmentCaractéristiques fonctionnelles des systèmes de renforcement: Étude comportementalePhysiology & Behavior, Vol. 16, No. 4Self-stimulation thresholds and dorso-ventral variation in the lateral hypothalamus in mouse: Effects of food and water deprivationPhysiology & Behavior, Vol. 16, No. 2Modulation of reward and aversion processes in the rat diencephalon by neuroleptics: Differential effects of clozapine and haloperidolPsychopharmacology, Vol. 49, No. 1The effects of medial hypothalamic stimulation on escape from footshockBehavioral Biology, Vol. 15, No. 2The motivational properties of electrical stimulation of the guinea pig diencephalonBehavioral Biology, Vol. 15, No. 2Proceedings of the Australasian Society of Clinical and Experimental PharmacologistsClinical and Experimental Pharmacology and Physiology, Vol. 2, No. 5Anatomically-dependent facilitation and inhibition of hypothalamic self-stimulation by food deprivationBehavioral Biology, Vol. 13, No. 2Assessing the aversiveness of intracranial stimulationPsychopharmacologia, Vol. 44, No. 2Catecholamine systems as the neural substrate for intracranial self-stimulation: a hypothesisBrain Research, Vol. 73, No. 3Reinforcement contrast effects on the rewarding and aversive components of intracranial stimulationLearning and Motivation, Vol. 4, No. 4 More from this issue > Volume 224Issue 1January 1973Pages 62-65 Copyright & PermissionsCopyright © 1973 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1973.224.1.62PubMed4566851History Published online 1 January 1973 Published in print 1 January 1973 Metrics

Influence of contingent amygdaloid stimulation on lateral hypothalamic medial forebrain bundle self-stimulation

Rats were trained to self-stimulation for lateral hypothalamic medial forebrain bundle self-stimulation. When simultaneous ipsilateral amygdaloid stimulation accompanied each bar-press, there was an increase in response rate and a decrease in threshold for lateral hypothalamic self-stimulation. The same effect was observed after bilateral lesion of stria terminalis (Experiment 1). The increase in excitability of the lateral hypothalamic rewarding neurons in response to the contingent amygdala stimulation was also demonstrated by the findings that incentive shifts, indicated by positive and negative contrast effects, appeared when amygdala stimulation was started or interrupted, respectively (Experiment 2). On the basis of experimental data and the related literature it is assumed that the amygdala cannot represent a primary or basic reinforcing mechanism, but it has a definite role in the neural mechanism of central processes of higher level, whose control on the basic neuronal mechanism of reward may only be important in the organization of more complex forms of adaptive behavior.

Behaviorally determined neurophysiological properties of MFB self-stimulation fibers

A number of experiments have demonstrated that such neurophysiological properties as latent addition, neural refractoriness and temporal summation can be behaviorally measured in double pulse studies of the self-stimulation system of the rat. Since these phenomena have been investigated exclusively in the posterior lateral hypothalamic medial forebrain bundle (PH-MFB) or in the ventral tegmental area of the midbrain, the present experiment investigated these properties in an anterior area of the MFB. Eight rats were tested with PH-MFB electrodes and nine rats were tested with anterior preoptic electrodes (POA-MFB). The double pulse derived self-stimulation curves revealed: (a) a higher overall rate of responding for PH-MFB self-stimulation than for POA-MFB self-stimulation even though a higher current level was needed for POA-MFB self-stimulation; (b) refractory period differences between POA-MFB and PH-MFB electrodes; (c) evidence for latent addition; and (d) evidence for temporal summation. These results are discussed in terms of self-stimulation mapping studies of the rat diencephalon, the anatomy of the MFB, and previous double pulse self-stimulation studies.

Topographical differences in the responses of single hypothalamic neurons to limbic stimulation.

ARTICLESTopographical differences in the responses of single hypothalamic neurons to limbic stimulationJT Murphy, JJ Dreifuss, and P GloorJT Murphy, JJ Dreifuss, and P GloorPublished Online:01 Jun 1968https://doi.org/10.1152/ajplegacy.1968.214.6.1443MoreSectionsPDF (2 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByParticipation of NMDA receptors in the lateral hypothalamus in gastric erosion induced by cold-water restraintPhysiology & Behavior, Vol. 140Gastric mucosal erosion produced by NMDA microinfusions in the lateral hypothalamus: effect of selective knife cutsBehavioural Brain Research, Vol. 102, No. 1-2The lateral hypothalamic area revisited: Neuroanatomy, body weight regulation, neuroendocrinology and metabolismNeuroscience & Biobehavioral Reviews, Vol. 17, No. 2Interconnectedness of Steroid Hormone-Binding Neurons: Existence and ImplicationsNeurophysiological analysis of the development of endocrine and hypertensive reactions in prolonged emotional stressBrain Research, Vol. 344, No. 2An electrophysiological study of the neural projections from the hippocampus to the ventral pallidum and the subpallidal areas by way of the nucleus accumbensNeuroscience, Vol. 15, No. 4A [14C]2-deoxyglucose analysis of the functional neural pathways of the limbic forebrain in the rat. I. The amygdalaBrain Research Reviews, Vol. 5, No. 1Lateral septum-medial hypothalamic connections: An electrophysiological study in the ratNeuroscience, Vol. 7, No. 11Mechanism of inhibition by the amygdala in the lateral hypothalamic area of ratsBrain Research Bulletin, Vol. 8, No. 6Electrophysiological responses of neurons of the ventral tegmental area to electrical stimulation of amygdala and lateral septumNeuroscience, Vol. 6, No. 3INTRODUCTION TO PSYCHOPHYSIOLOGY OF MOTIVATION (ORGANIZATION OF THE CORTICO-LIMBIC-RETICULAR AXIS IN REGULATING HYPOTHALAMIC ACTIVITY)Influence of midbrain stimulation on the excitability of neurons in the medial hypothalamus of the ratBrain Research, Vol. 174, No. 1Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and catThe Journal of Comparative Neurology, Vol. 178, No. 2Role of the Amygdaloid Complex in the Secretion of Antidiuretic Hormone and OxytocinUnitary responses of the hypothalamic nuclei to stimulation of the frontobasal neocortexNeurophysiology, Vol. 10, No. 1Comparative effects of amygdala and central gray matter of the midbrain on lateral hypothalamic unit activityNeurophysiology, Vol. 9, No. 1BibliographyProlonged medial forebrain bundle unit responses to rewarding and aversive intracranial stimuliBrain Research Bulletin, Vol. 1, No. 6Infant rats: Hypothalamic unit activityBrain Research Bulletin, Vol. 1, No. 6Unit responses in hypothalamus and mesencephalic reticular formation to acoustic stimuli and electrical stimulation of ipsi- and contralateral amygdalaPhysiology & Behavior, Vol. 17, No. 4Septal-Hypothalamic RelationshipsEvaluation of extrahypothalamic control of reproductive physiology21 June 2005Acetylcholine, an inhibitory transmitter in the rat lateral hypothalamusBrain Research Bulletin, Vol. 1, No. 1Extralimbic mediation of emotionality and social cohesiveness effectsPhysiology & Behavior, Vol. 15, No. 3The ventromedial hypothalamus and the control of avoidance behavior and aggression: Fear hypothesis versus response-suppression theory of limbic system functionBehavioral Biology, Vol. 15, No. 1Effects of electrical stimulation of the lateral habenular nucleus and lateral hypothalamus on unit activity in the upper brain stemBrain Research, Vol. 78, No. 3Effects of electrical stimulation of the lateral hypothalamus, hippocampus, amygdala and olfactory bulb on unit activity of the lateral habenular nucleus in the ratBrain Research, Vol. 77, No. 3An analysis of the effects of septal lesions on negatively reinforced behaviorBehavioral Biology, Vol. 9, No. 2The neurobiology of motivated behaviorProgress in Neurobiology, Vol. 1Influence of contingent amygdaloid stimulation on lateral hypothalamic medial forebrain bundle self-stimulationPhysiology & Behavior, Vol. 9, No. 5Effect of electrical stimulation of the septum and the lateral preoptic area on unit activity of the lateral habenular nucleus in the ratBrain Research, Vol. 43, No. 2Projections of the septum to the lateral hypothalamusExperimental Neurology, Vol. 34, No. 2Effects of Electrical Stimulation of the Amygdaloid Complex on the Ventromedial HypothalamusAmygdaloid-Hypothalamic Neurophysiological InterrelationshipsRelationships among Amygdaloid and Other Limbic Structures in Influencing Activity of Lateral Hypothalamic NeuronsThe Role of the Amygdala in Controlling Hypothalamic OutputTemporal Lobe Epilepsy: Its Possible Contribution to the Understanding of the Functional Significance of the Amygdala and of Its Interaction with Neocortical-Temporal MechanismsForebrain activation of single units in preoptic area of sunfishComparative Biochemistry and Physiology Part A: Physiology, Vol. 40, No. 3Effect of septal stimulation on lateral hypothalamic unit activity in the ratBrain Research, Vol. 32, No. 1Effects of septal stimulation on drinking elicited by electrical stimulation of the lateral hypothalamusExperimental Neurology, Vol. 32, No. 3The response of single lateral hypothalamic neurons to ventromedial nucleus and limbic stimulationPhysiology & Behavior, Vol. 6, No. 5ELECTROPHYSIOLOGICAL STUDIES OF AMYGDALO-HYPOTHALAMIC CONNECTIONSAnnals of the New York Academy of Sciences, Vol. 157, No. 2 Neural RegulaInhibitory interneurons in the ventromedial nucleus of the hypothalamusBrain Research, Vol. 9, No. 2 More from this issue > Volume 214Issue 6June 1968Pages 1443-1453 Copyright & PermissionsCopyright © 1968 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1968.214.6.1443PubMed4870150History Published online 1 June 1968 Published in print 1 June 1968 Metrics

Contrasting effects of two identified amygdaloid efferent pathways on single hypothalamic neurons.

Contrasting effects of two identified amygdaloid efferent pathways on single hypothalamic neurons.