Main Actor Research Articles

Proposal to improve the patient journey for women's cardiovascular prevention

The relevance of gender medicine in cardiovascular prevention is still underestimated, and there is a lack of viable women-specific preventive, diagnostic, and therapeutic strategies. To ensure women have equal access to cardiovascular prevention, cardiovascular disease risk stratification needs to consider gender-specific factors related to women reproductive cycle phases together with the different impact that traditional risk factors have on men and women. The aim of this document is to improve the patient journey for cardiovascular risk prevention in women, enhancing the importance of a multidisciplinary approach and the role of the various professional figures involved, starting with the general practitioner, as the main actor of the first risk stratification. The goal of the proposed patient journey is to ensure effective risk assessment of cardiovascular disease in women, by raising attention on the risk factors related to different hormonal phases and to bridge the sex and gender gap in cardiovascular prevention. We hope that this journey can be implemented as uniformly as possible in clinical practice throughout Italy.

Visionary Leadership Kepala Madrasah dalam Mengembangkan Budaya Organisasi yang Inklusif dan Berdaya Saing di Lembaga Pendidikan Islam

This study aims to determine the visionary leadership of madrasah heads in developing an inclusive and competitive organizational culture in Islamic educational institutions. This study uses a literature study method to identify and analyze the results of previous research that are relevant to the topic. The source of data for this research comes from various articles published through google scholar, Journal, and PubMed. The data analysis technique used is qualitative data analysis consisting of data reduction, data presentation, and conclusion drawing. The findings of this research are that the visionary leadership of the head of the madrasah is the ability of the head of the madrasah to create, formulate, communicate, and implement ideal ideas that come from him or the result of social interaction among madrasah members as the ideals of the madrasah in the future that must be achieved or realized through the commitment of all personnel. The development of organizational culture in schools cannot be separated from the leadership role of the principal as the main actor who determines and colors the lives of school residents. The visionary leadership of the head of the madrasah must be able to create a conducive organizational culture. The same steps and vision in carrying out duties and responsibilities must be possessed by each member so that everyone can improve his or her professionalism.

Subjective Matrix оf Vertical Political Communication

The article provides a brief overview of various aspects of research into subjects of political communication, analyzing their key characteristics and distinctive features. The authors introduce their own typology of political communication through the construction of a vertically integrated communication matrix. The key characteristics of each type of political communication and the main subjects of communication, their goals and degree of nativeness are described in detail. In the course of the study, the authors come to the conclusion that the leading role in the subject matrix is played by the dominant type of political communication, where the main actor is the highest official of the state.

Implementation of Biological Learning Management to Produce Productive Teachers

The implementation of learning management plays a very decisive role in the teaching and learning process. The biology teaching and learning process is the core of the formal education process, with the teacher as the main actor. This research uses the field study method (Field Research). Sources of data in this study using the purposive sampling technique. The data collected are data collection (field notes), data reduction (data reduction), data display (data presentation), and conclusion drawing/verification. The results of this study are teachers are very skilled in prioritizing the ability to open lessons, prioritizing Mastery of learning materials, referring to planned teaching and learning activities, and prioritizing the ability to use learning media. The implementation of biology learning management in this study includes four main functions in education management: planning, organizing, acting, and evaluating. Thus, good school management certainly produces school principals with good educational management implementation and has productive teachers in the teaching process in schools.

Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer’s mouse model and stimulates synaptic plasticity pathway enzymes

The Ketogenic Diet (KD) improves memory and longevity in aged C57BL/6 mice. We tested 7 months KD vs. control diet (CD) in the mouse Alzheimer’s Disease (AD) model APP/PS1. KD significantly rescued Long-Term-Potentiation (LTP) to wild-type levels, not by changing Amyloid-β (Aβ) levels. KD’s ‘main actor’ is thought to be Beta-Hydroxy-butyrate (BHB) whose levels rose significantly in KD vs. CD mice, and BHB itself significantly rescued LTP in APP/PS1 hippocampi. KD’s 6 most significant pathways induced in brains by RNAseq all related to Synaptic Plasticity. KD induced significant increases in synaptic plasticity enzymes p-ERK and p-CREB in both sexes, and of brain-derived neurotrophic factor (BDNF) in APP/PS1 females. We suggest KD rescues LTP through BHB’s enhancement of synaptic plasticity. LTP falls in Mild-Cognitive Impairment (MCI) of human AD. KD and BHB, because they are an approved diet and supplement respectively, may be most therapeutically and translationally relevant to the MCI phase of Alzheimer’s Disease.

FINANCIAL STATEMENT ANOMALY DETECTION BASED ON BENFORD LAW AND BENEISH MODEL: CASE OF A PUBLIC SECTOR HOSPITAL

Public financial management reforms played an important role in the restructuring of social institutions and organizations. Researchers examined the effects of the reform according to their expertise. However, the research has focused on the results and the effects of the results rather than focusing on the starting point of the actions of the main actors who are the source of knowledge. In our research, first of all, the social life world of a public hospital was schematized. The hospital information management system (HIS) data, where the main actor actions are recorded at the starting point of the information source, was accessed and the accuracy of these data was analyzed with Benford’s Law, which can be considered as data mining. There are two databases (subsystems) in the public hospital where sales revenues are tracked. These are HIS and uniform accounting system (UAS). The information produced in HIS consists of unstructured data. By structuring this data with accounting information, HIS financial statement variables were created. Logit analysis, which is considered one of the machine learning techniques, was performed using the HIS financial statement variables and the existing UAS financial statement variables Beneish Model. It was found that there is a statistically significant difference between HIS financial statements and UAS financial statements. It is argued that this difference can be eliminated by using accounting language (accounting coding system).

Pendidikan Khusus Profesi Advokat Dewan Pimpinan Nasional Persatuan Advokat Indonesia Dan Profesi Advokat Berdasarkan Pasal 3 Ayat (1) Huruf F Undang - Undang Republik Indonesia Nomor 18 Tahun 2003 Tentang Advokat

Special Education for the Advocate Profession (PKPA) is a mandate from Law of the Republic of Indonesia Number 18 of 2003 concerning Advocates. Special Education for the Advocate Profession is a form of education that must be followed by someone with a bachelor's degree with a higher legal education background. Special Education for the Advocate Profession (PKPA) has relevance to the Law of the Republic of Indonesia Number 20 of 2003 concerning the National Education System (SISDIKNAS) which states that the types of education consist of general, vocational, professional, vocational, religious and special education. This Community Service activity aims to produce professional lawyers who are reliable, independent and responsible so that they are able to appear as enforcers of justice in administering justice honestly and in accordance with legal objectives, namely, legal justice, legal benefits and legal certainty for all by enforcing equality at the forefront. before the law. This activity was attended by 30 (thirty) prospective advocate participants which was held on October 14 2023 at Tangerang Raya Tiga Raksa University, Tangerang Regency. The method used by Service Learning (SL) is intended to integrate learning into the Special Education for the Advocate Profession (PKPA) or the partnership of the National Leadership Council of the Indonesian Advocates Association (DPN PERSADIN) with the Faculty of Law, University of Greater Tangerang (UNTARA). Apart from that, the Participatory Action Research (PAR) approach is oriented towards empowering participants in Special Education for the Advocate Profession (PKPA). This is due to the need and resolution of legal problems in society. Higher education officials must place society as the main actor in development and change. The result of this activity is to give birth to the profession of advocates and provide an understanding that Advocates are a profession that is noble, free, independent and responsible in upholding the law, and that the activities of this profession are guaranteed and protected by law for the sake of implementing the Rule of Law.

Branding Capres Dan Konstruksi Wacana Politik Pilpres 2024 Di Ruang Media Sosial

ABSTRACT Social media is the most effective space for image branding and political construction for candidate who will compete in the 2024 presidential election. Currently, social media platforms (Facebook, Instagram, Youtube, Twitter and TikTok) are widely used by candidate to create an impression, polishing the image, forming a reputation, and constructing the identity of each candidate. This study aims to expand the branding and political construction of the presidential/vice presidential candidate's image in the 2024 presidential election through social media as another form of digital campaign that has not been fully effective in realizing news democratization in the virtual space. Through a qualitative approach with a descriptive case analysis method, this study found the fact that social media is the main actor in idea marketers, framing actors, and agenda setting organizers who provide access to news and evaluations (approval, justification, denial) of each other's image, reputation, and identity each candidate who will compete in the 2024 presidential election, with variations framing, degree of branding, and different accentuations of political construction.

Pentad Analysis of Presidential Elections 2024 on Social Media

This article aims to analyze Ganjar Pranowo's posts on social media. Ganjar Pranowo is one of the presidential candidates who has great potential in the 2024 presidential election because he is one of the candidates from the winning party (incumbent) in the previous election. As a presidential candidate, Ganjar realizes the importance of social media in socializing himself and building a positive image as a presidential candidate. One social media platform that is well managed is Instagram. On his Instagram account, namely @ganjar_pranowo, Ganjar posts all his activities as part of political communication in an effort to attract the attention of the Indonesian people ahead of the election. The research method used is a qualitative method with pentad analysis consisting of 5 elements: act, scene, agent, agency and purpose). The research results found that Ganjar plays as the main actor and rhetorical communicator (act); applies election and social media (scene); roles as a political actor with a humanist and simple figure (agent); nationalist-religious (agency); and he attracts public attention, public sympathy and winning elections (purpose).

Defense Economic Diplomacy in Overcoming the Impact of the Israel - Hamas War on Indonesia's Economic Resilience

One of the most real threats from the increasingly heated Hamas-Israel conflict is the soaring world crude oil prices. Geographically, the proximity of the conflict in the Middle East is quite close to oil-producing countries. If the supply or distribution of oil from this area is disrupted. A significant increase in oil prices in a short time can have a tremendous shock effect on the market, the impact of this increase in commodities will spread to the national economy. This research was conducted using descriptive analysis. The process of Israel's annexation of Palestine will be described and analyzed in detail. The Indonesian government, through the first paragraph of the preamble to the 1945 Constitution, has the obligation to realize world peace by creating a new environment free from sovereignty conflicts, and clear and well-defined authority over economic activities that can take the Palestinian economy further towards the path of higher development and growth. Playing a direct diplomatic role by becoming the fifth of four countries currently the main actor in maintaining peace in the Middle East.

Betting the farm: Rural illiberal State-building in Angola via Chinese loans

Abstract Angola’s government has historically championed the revival of the agricultural sector as a national priority, though it has remained unclear what role the nation’s peasantry is intended to play. Looking to the future while fixated on the past, the first failed recipe for growth was initially based on nationalizing the colonial export model by incorporating the social and economic forces of the rural economy. The government’s early embrace of authoritarian modernization has since pursued an illiberal rural development model seeking to entrench the state’s control over rural areas and extend elite reproduction capacities, exercised principally through a series of state-owned enterprises. Upon the end of the civil war in Angola in 2002, the timely arrival of Chinese loans and technical assistance allowed the administration of President José Eduardo dos Santos to revitalize this strategy with a return to the establishment of a series of state agro-industrial farms a quarter century later. A historical presidential transition in 2017 upended these strategies of rural governance, leading to a vast privatization scheme of state assets built up over decades. This article reveals how the Angolan state has historically sought to engineer elite minority control over the agricultural sector while marginalizing the vast majority of the main rural economic actor, the peasantry. Likewise, the case study provides insight into the hidden costs of Chinese loans on Angola’s rural economy.

Duration of DAPT After Stent Implantation, How Low Can We Go?

Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is the main actor in secondary prevention of recurrent coronary ischemic events and stent thrombosis. For this exact purpose the combination of two antiplatelet molecules have proven efficacy and superiority compared to monotherapy, aspirin alone, but this comes with an increased risk of major and potentially fatal bleedings, making the choice of the molecules and especially the duration of treatment a true challenge for every cardiologist. We are going to discuss some of the main factors that play a role in the decision, and the most important trials that studied the subject.

Peptide and peptidomimetic tyrosinase inhibitors.

Melanin, which is produced by melanocytes and spread over keratinocytes, is responsible for human skin browning. There are several processes involved in melanogenesis, mostly prompted by enzymatic activities. Tyrosinase (TYR), a copper containing metalloenzyme, is considered the main actor in melanin production, as it catalyzes two crucial steps that modify tyrosine residues in dopaquinone. For this reason, TYR inhibition has been exploited as a possible mechanism of modulation of hyper melanogenesis. There are various types of molecules used to block TYR activity, principally used as skin whitening agents in cosmetic products, e.g., tretinoin, hydroquinone, azelaic acid, kojic acid, arbutin and peptides. Peptides are highly valued for their versatile nature, making them promising candidates for various functions. Their specificity often leads to excellent safety, tolerability, and efficacy in humans, which can be considered their primary advantage over traditional small molecules. There are several examples of tyrosinase inhibitor peptides (TIPs) operating as possible hypo-pigmenting agents, which can be classified according to their origin: natural, hybrid or synthetically produced. Moreover, the possibility of variating their backbones, introducing non-canonical amino acids or modifying one or more peptide bond(s), to obtain peptidomimetic molecules, is an added value to avoid or delay proteolytic activity, while the possibility of conjugation with other bioactive peptides or organic moieties can bring other specific activity leading to dual-functional peptides.

РАДЯНСЬКА ПОПУЛЯРНА МУЗИКА В 1960–1980-х рр.: ЗАГАЛЬНА ХАРАКТЕРИСТИКА Й ТЕНДЕНЦІЇ РОЗВИТКУ

The article is devoted to the development of Soviet popular music in the 1960s – 1980s. The author analyzed the song’s characteristics, identified the distinguishing features of the performer’s image and identified the main development trends. Internal and external influences on popular music are also highlighted. On the one hand, this is a factor of the penetration of Western pop culture, and on the other hand, the traditions formed under the influence of ideology within the USSR. For a long time, the official pop music was almost the only permitted option for musical creativity in the totalitarian system. It was characterized by a high level of performance skill and an orientation to the academic tradition, a predominance of a clear and refined melody, patriotic and intimate lyrics, as well as restraint and modesty of manners and a generally conservative image of the artist. At the same time, there was a search for new musical and textual forms, manifested in an appeal to more pronounced melodism, and artists’ experiments with their own style, when typical and strict clothes were replaced by bright and original outfits, the work of VIA was a vivid expression of this. As an alternative to the pop music, an amateur author’s song appears and develops. For the author’s song of the romantic direction, which arose during the period of Khrushchev’s liberalization, idealization of military achievements, travels and life trials, which were full of lyricism and light humor, was inherent in the romantic form; however, later, with the beginning of the collapse of the liberal course, the protest work of bards came to the fore – the themes of exposing cruelty began to dominate, irony and sarcasm appeared in the texts, and in some places the vocabulary was reduced. The image of a Soviet bard was formed – a poet-musician with a guitar. During Gorbachev’s socio-political transformations, the state, which used to be the main actor in musical culture, conceded its positions to young representatives of amateur creativity. That’s when disco and rock music become popular. Disco was characterized by an orientation towards rhythmic textures and themes of urban romances, while the manner and image of the performers were dominated by looseness and extravagance. Soviet rock was based on «big beat» and the social themes of the lyrics, and the artist’s style stood out for its simplicity and freedom. Pop music begins to depart from the formed tradition, adopting certain features of disco and even rock. More electronic music is appearing, lyrics are becoming less serious, expressing simpler meanings, and artists’ styles are becoming more casual.

Інвестиційне забезпечення видобутку вуглеводневої сировини в США: основні тренди, енергетичні альтернативи та екологічні детермінанти

It is substantiated that the United States are present as the main actor in the global energy market in terms of both forming the supply of energy carriers and ensuring the stability of its functioning. It is found that in recent decades, the production of hydrocarbons in the United States has been regulated by the federal government, based on conjunctural fluctuations in the world hydrocarbon market and the reformatting of the centers of gravity in global energy flows. It is found that in 2010–2022 in the United States, despite the growth of hydrocarbon production, there was a decrease in the volume of investment support for the development of the oil and gas industry. It is proved that the reduction of investment injections into oil and gas production in recent years is due to the diversification of the investment portfolio of «hydrocarbon» TNCs and the change in priorities in the development of hydrocarbon reserves. It is identified that the diversification of the investment portfolio of oil and gas companies occurs through the transfer of financial flows to the development of alternative energy and giving priority to the implementation of small, less risky megaprojects, rather than excessively risky megaprojects. It is substantiated that the United States has formed a diversified investment landscape in the field of natural gas and oil production, which includes large transnational corporations, independent oil and gas companies, financial institutions, and private investment companies. It is agreed that one of the main priorities of investment support for hydrocarbon extraction projects is the extraction of shale gas, based on its significant reserves and taking into account the emergence of new niches in the capacious market of Western Europe as a result of the imposition of sanctions against oil and gas suppliers from terrorist countries. It is verified that an effective form of investment support for shale gas extraction are public-private partnership (PPP) agreements, which provide investment in the development of the infrastructure of technological and innovation centers, which are focused on the development of advanced technologies related to the exploration, production and use of this component of hydrocarbon raw materials. This creates conditions for gaining competitive advantages in the volatile and sensitive global oil and gas market.

Pentahelix Model In Community-Based Tourism Development In Situbondo District

Community-based tourism is part of sustainable tourism development. Community-based tourism involves the community as the main actor in its management and aims to increase economic and industrial activities, preserve culture, and improve the economies of local communities. This research aims to describe the pentahelix model in community-based tourism development in Situbondo Regency, East Java. The research method used is qualitative research with a case study approach. The research data were collected from observations, interviews and documentation. The research data were analyzed descriptively and qualitatively. The results showed that community-based tourism development in Situbondo Regency has involved collaboration among actors in the pentahelix model, namely local government, academics, industry and business, the community, and mass media. The local government acts as a regulator in formulating policies related to community-based tourism management. The community, as the manager of community-based tourism, prepares institutional planning and organization and builds cooperation with academics and businesses in developing innovation, knowledge and competence in human resources and business management. The mass media play a role in the promotion and marketing of community-based tourism. However, the cooperation between the actors in the pentahelix model has not been optimal, especially with the limited involvement of industry/business and mass media. There is a need to strengthen cooperation among actors and to strengthen the institutional capacity of the community as a manager of community-based tourism.

Upaya Pemerintah Provinsi Riau dalam Menangani Kasus Kebakaran Hutan Riau berdasarkan ASEAN Agreement on Transboundary Haze Pollution

This research discusses the efforts of the Riau Provincial Government in raising awareness among the local community to prevent forest and land fires, which have become a serious issue in the Southeast Asian region. Grounded in the theories of compliance, neoliberal institutionalism, and the concept of international regimes, this study reveals that Indonesia, as the main actor in the ASEAN Agreement on Transboundary Haze Pollution (AATHP), has made efforts to comply with the agreement. Preventive measures against forest and land fires involve the central and local governments, as well as the active participation of local communities. Education and socialization programs about the dangers of forest and land fires, relevant regulations, and their negative impacts are crucial components of the prevention strategy. Furthermore, private companies such as Asian Agri and PT SRL play a significant role in supporting these prevention programs. The research findings indicate that despite numerous efforts, the issues of forest fires and transboundary air pollution remain serious concerns in the Southeast Asian region. AATHP, as a binding legal framework for Indonesia, requires more extensive and sustainable efforts to achieve the desired goals of preventing transboundary air pollution. Community awareness and cooperation between government, private entities, and NGOs will be key to addressing this issue.

Global Justice’s Critics of Green Politics Theory Towards International Rules of Climate Change

Environmental issues have become a concern issues in the last decades. Green Politics emerge as an enforcement from the global community because of the climate change problem in the world. Green Politics emphasized on the decentralization of power to solved the environmental issues. The role of individual become important in solving environmental issues. If each individual has the similar awareness,it could be solved the environmental issues. Global Justice come up and claimed as a solution to see the environmental problems. According to global justice, the equal right in opportunities is the key of handling the climate change. States is an actor that can facilitated the movement of climate change. The perception of global justice perceive if individual is the main actor in environmental issues, it would not be unfair to individual in the developing countries. Distributive of justice is needed to make developing countries have a similar opportunities to reach a similar improvement liked developed countries.

MODEL PENTAHELIX PADA WISATA BERBASIS MASYARAKAT DI PULAU LEMUKUTAN BENGKAYANG

Beach tourism in Lemukutan Island is located in Bengkayang Regency, West Kalimantan Province is one of the tourist objects in West Kalimantan that used the concept of community-based tourism (CBT), this research uses a descriptive qualitative approach that is field research, the data in this research is collected through interview, observation and documentation. This study aims to explain the role of the community in managing tourism on Lemukutan Island and to understand the pentahelix collaboration model on tourism that synergizes other stakeholders to build tourism sustainability in after the Covid-19 pandemic, and explain the economic impact for the community of tourism on Lemukutan Island. The results showed that the community have an essential role in the sustainability of tourism, the community's ability to manage tourism can attract some other stakeholders to synergizes in developing a Lemukutan Island tourism, especially after the Covid-19 pandemic, as a result the economy of the Lemukutan Island community has also increased. The pentahelix model in tourism development on Lemukutan Island involves five main actors, namely the community or society as the main actor managing tourism, government, Business or private companies, academic and media. The participation of these stakeholders, Lemukutan Island tourism will continue to exist in the future.

The SOCIAL NETWORK ANALYSIS EFEKTIVITAS PROMOSI PARIWISATA MELALUI TAGAR #BATUKOTAWISATA DI TWITTER


 
 
 
 The tourism sector in Indonesia has been badly affected by the covid 19 pandemic. Slowly the tourism sector is starting to revive along with the shift of covid 19 from a pandemic to an endemic one. One of the quick strategies in the revival of the tourism sector is the movement of domestic tourists to local Indonesian destinations. The movement of domestic tourists can be triggered by tourism promotions. Using the social network analysis method, this research wants to see the effectiveness of tourism promotion through the hashtag #BatuKotawisata on Twitter social media. The results of the study show that tourism promotion through the #BatuKotawisata hashtag on Twitter is not effective because the main actor spreading the hashtag is not an actor with an interest in the tourism sector. The main actor brings his own interests through the message conveyed in the hashtag #BatuKotawisata. The positive thing that can be seen in tourism promotion through the #BatuKotawisata hashtag is that this hashtag has penetrated trending topics.