Low-intensity Laser Research Articles

Effects of Laser and Sacroiliac Joint Mobilization for Sacroiliac Joint Dysfunction

To evaluate the effects of laser and sacroiliac join mobilization for sacroiliac joint dysfunction.The SI Joint`s primary functions are to provide to distribute trunk load to the lower limbs. Lowback discomforts are frequently caused by sacroiliac joint dysfunction (SI) Joint, which can bedifficult to diagnose. Prolonged standing or sitting postures can also make pain worse. Low Intensity Laser Therapy also known as Low Level Laser Therapy is thought to work by inducing a photochemical-reaction (Response) to light (Laser) Physiotherapist frequently Recommend spine mobilization to treat Musculoskeletal Problems. The Amplitude of Oscillating mobilization can be classified as considerable (GradesII and III) or little (Grades I and IV) depending on the possible range of motion. 5 Large amplitude oscillations excite more mechanoreceptors and hence reduce pain more effectively than small amplitude oscillations. To evaluate the effects of laser therapy and laser therapy with sacroiliac joint mobilization in patient with sacroiliac joint dysfunction. The total number of test subjects was 40. The Group(A) 20 Samples) and Group(B) 20 Samples, both groups pre and post-test values noted NPRS scale. Group-A Laser therapy was given by patient being in prone lying position and Group-B Laser therapy with sacroiliac joint mobilization techniques was given in being pronelying position. Both Groups treatment Will be given 4 weeks for Thrice a week for 30 minutes. This study was conducted as a experimental study. The sample were collected by convenient sampling technique. The data that had been gathered was statistically analyzed using an unpaired t-test. Compared to the laser group, the Laser with sacroiliac joint mobilization group exhibits significant effects in lowering pain and improving physical functional activity, as assessed by NPRS scale. It is concluded that laser therapy with sacroiliac joint mobilization technique was found to be more effective than laser therapy in sacroiliac joint dysfunction. Key Words: Sacroiliac joint dysfunction, Laser, Maitland mobilization Technique

Enhanced THz Radiation from Spatially Inhomogeneous Fields

Nonlinear terahertz (THz) radiation from gas media usually relies on the asymmetric laser-induced current produced by ultra-intense two-color laser fields with a specific phase delay. Here a new scheme is proposed and theoretically investigated, in which the radiation is generated by spatially inhomogeneous fields induced by relatively low-intensity monochromatic lasers and an array of single triangular metallic nanostructures. Our simulations are based on the classical photocurrent model and the time-dependent Schrödinger equations separately. It is found that the collective motion of the ionized electrons can be efficiently controlled by the inhomogeneous field, resulting in strong residual currents. The intensity of the THz radiation could be enhanced by about two orders of magnitude by increasing the spatial inhomogeneity of the field.

Control of the Pseudomonas aeruginosa growth by low-intensity laser therapy

Control of the Pseudomonas aeruginosa growth by low-intensity laser therapy

Experimental Determination of the Stability of the «Flamena» Gel Pharmacological Structure under the Influence of Low-Intensity Laser Radiation

In modern dentistry, the problem of the prevention and treatment of peri-implantitis is relevant. Proposed methods of treating patients with peri-implantitis do not stop the pathological process with the possibility of achieving long-term remission. Liposomal complexes with dihydroquercetin make it possible to influence the pathogenetic links of the inflammatory process in periodontal tissues with the prospect of normalizing blood circulation and regeneration processes in the affected area. It has been established that the complex simultaneous effect of low-intensity laser radiation and a pharmaceutical (laserophoresis) provides the possibility of more significant penetration of the drug components into periodontal tissues. The study of the laserophoresis of the liposomal complex with dihydroquercetin in the treatment of patients with peri-implantitis is relevant. However, in the modern literature, there is a lack of studies on the effect of low-intensity laser radiation on the pharmaceutical structure of drugs based on the above-mentioned basis.

Effectiveness of low-intensity laser photobiomodulation in reducing inflammatory events (pain, edema, and trismus) after orthognathic surgery: a systematic review and meta-analysis of randomized clinical trials.

This systematic review aimed to answer whether, in (P) individuals undergoing orthognathic surgery, (I) low-level laser therapy (LLLT) during or shortly after the surgical procedure compared to (C) pharmacologic therapy alone or no therapy for improvement of post-intervention complications relieves (O) postoperative inflammatory events in (S) randomized clinical trials. A preliminary electronic search was conducted for references with language following a Latin (Roman) alphabet in seven databases index, and gray literature without restriction on language or publication period. Risk of bias was performed by RoB 2.0 tool, and meta-analysis used mean differences (MD) for edema and mouth opening and standardized mean differences (SMD) for pain scores (p < 0.05, Revman®). A total of 91 control patients and 114 LLLT patients were included. The wavelengths ranged from 660 to 940nm, and the applied energy density was between 5 and 100J/cm2 at mostly extraoral distributed points. LLLT significantly reduced edema (MD = - 4.27, CI95% - 5.13 to - 3.41mm) in the period from 5days to 2weeks postoperatively (p < 0.001) and showed strongly reduced pain scores (SMD = - 1.37, I95% = - 1.99 to - 0.75) between 1day and 5weeks (p < 0.001), without significantly interfering with mouth opening (p = 0.110). Despite the low risk of bias, high heterogeneity among studies (I2 > 70%) and small sample sizes made the certainty of GRADE evidence low. This SR demonstrated that LLLT effectively controls pain and edema after orthognathic surgery. Systematic review that summarizes the use of photobiomodulation on orthognathic surgery.

Comparative assessment of clinical efficacy of different methods of medical rehabilitation in patients with rhinosinusitis polyposa

The article presents the results of a comparative assessment of the effectiveness of the course application of therapeutic physical factors (alternating magnetic field and low-intensity laser radiation) in complex medical rehabilitation of patients with moderate and severe rhinosinusitis polyposa with uncontrolled course. It was shown that the use of genetically engineered biological therapy (GEBT) with dupilumab contributed to the positive dynamics of the clinical parameters of sinonasal polyposis. Complementing GEBT with the course application of an alternating magnetic field was accompanied by an increase in the regression of the main clinical manifestations of rhinosinusitis polyposa. The maximum corrective activity was noted in the group with the complex use of therapeutic physical factors — an alternating magnetic field and low-intensity laser radiation against the background of GEBT. The growth is based on the ability of the complex use of physiotherapeutic factors to cause the development of synergistic phenomena through the use of corrective effects of different modality, having different mechanisms of action. The physical factors under consideration are able to improve hemo- and microcirculation in the area of chronic inflammation, exhibit anti-inflammatory, analgesic, and trophic-stimulating effects, which, together with the inactivation of the main pro-inflammatory interleukins of type 2 inflammation, enhances the sanogenetic potential that determines the duration of remission. Taking into account the chronic relapsing nature of the rhinosinusitis polyposa course, it is planned to conduct prolonged studies covering a follow-up period of 1.5–2 years.

Retracted: Application of Low-Intensity Laser in the Treatment of Skeletal Muscle Injury in Runners.

[This retracts the article DOI: 10.1155/2022/1211602.].

Major approaches to laser therapy in regenerative processes in bucco-maxillo-facial bone defects: a concise systematic review

Introduction: In the context of oral and bucco maxillo regenerative processes, bone defects are caused by trauma, surgery, tumor, congenital disease, and other pathological factors. Low-level laser therapy (LLLT) can regulate cellular functions by affecting cell growth and cytokine secretion, thereby exerting a variety of biological effects. Objective: It was to carry out a concise systematic review of the main stimulatory and regenerative effects of laser therapy on bone formation processes in maxillary oral surgery for bone defects. Methods: The systematic review rules of the PRISMA Platform were followed. The search was carried out from February to March 2023 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases, using articles from 1993 to 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed accordingly, according to the Cochrane instrument. Results and Conclusion: A total of 114 articles were found, 48 articles were evaluated and 29 were included and developed in this systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 16 studies with a high risk of bias and 40 studies that did not meet GRADE. It was concluded that there is scientific evidence of the positive effect of low-intensity laser energy on bone regeneration within a certain relationship between dose and output power. The low-intensity laser stimulates cellular metabolism, increasing protein synthesis and subsequent bone regeneration. A high dose combined with low potency or a low dose combined with high potency appears to produce a positive effect.

Photobiomodulation for Correction of Systemic Disorders of Experimental Pain Syndromes

The development of anti-pain technologies in the complex treatment of pain syndromes is one of the most urgent tasks of modern medicine. We undertook a placebo-controlled experimental study of the therapeutic potential of low-intensity laser radiation when applied to acupuncture points that are directly related to the autonomic nervous system. The adaptation effect of puncture photobiomodulation on the induction of stress-mediated autonomic reactions, oxidative metabolism and microcirculation in animals during the acute phase of pain stress was revealed. The data obtained are of interest for use in the complex rehabilitation of patients with pain syndromes.

Single-photon ionization of aligned H with near-ionization-threshold photon energy

We study single-photon ionization of aligned H in a high-frequency low-intensity laser field. We focus on the cases where the laser frequency is near to or somewhat larger than the ionization potential of the target. The calculated photoelectron momentum distribution through numerical solution of time-dependent Schrödinger equation shows clear interference patterns. However, different from the cases of photon energy far larger than the ionization potential usually explored in experiments, the positions of interference maxima and minima for the present cases can not be explained by the interference of the electronic wave with the observed momentum between these two atomic centers of the molecule. By developing a theory model applicable for ionization of molecules in high-frequency laser field, we show that the Coulomb potential plays an important role in the momentum component of the emitting electronic wave near the nuclei, resulting in a remarkable shift of the interference pattern. A simple expression with Coulomb-modified momentum is obtained to predict the interference extrema, which gives suggestions for probing the structure and electron dynamics of the aligned molecule in single-photon ionization with lower photon energy.

Low-intensity laser diode plus extracorporeal shock wave therapy: a new treatment strategy in the management of Peyronie's disease.

To assess the clinical effectiveness of extra corporeal shockwave therapy (ESWT) administration compared with ESWT plus a low-intensity laser diode therapy (LILDT) in the management of Peyronie's disease (PD) stable stage. In this study, 214 patients affected by PD in stable stage (≥ 12months), were divided into two groups. Group 1 (G1) counted 111 patients treated only with ESWT; Group 2 (G2) consisted of 103 patients that received ESWT with the same protocol of G1 plus LILDT for six weeks. The patients of both groups were assessed at baseline and follow-up for erectile function, painful erections, penile plaque size and penile curvature. The results were evaluated at baseline and 3, 6, 12months after the treatment. Three months after the treatment in G2 pain in an erection or during intercourse was resolved completely in 78.6% of the patients, whereas in 55.8% cases of G1 (p < 0.003). G2 patients had a reduction of curvature degree after the 3months treatment (p < 0.002). However, mean plaque size decreased in both groups without statistically differences with baseline values. Mean ± SD IIEF-5 score further improved significantly in the group treated with ESWT plus LILDT (p < 0.001). There were no permanent adverse sequelae after treatments. This study demonstrates an interesting therapeutic strategy when combined to the synergistic action of a shock wave therapy with low-intensity laser therapy on the stable plaques with significant benefits in terms of pain perception, penile curvature and sexual activity.

Combined treatment of idiopathic male infertility using low-intensity laser therapy and complex prostate peptides: single-centre experience

Introduction. The study of effective and safe combined methods of conservative treatment of idiopathic male infertility is of great interest.Objective. To evaluate the effectiveness of the combined use of low-level laser therapy (LLLT) in the infrared (IR) spectrum and bioregulatory therapy with complex prostate peptides on the semen parameters and sperm DNA fragmentation (SDNAF) in men with idiopathic infertility.Materials &amp; methods. The study is based on the results of examination and treatment of 97 men with idiopathic infertility. Prior to the start of treatment, all patients were divided into three groups by randomization. Patients in group 1 (n = 34) underwent a course of LLLT in the IR spectrum consisting of 10 procedures q.o.d. Patients in group 2 (n = 31) were prescribed complex prostate peptides Supp. Prostatilen® AC (30 + 180 mg) PR q.h.s. FXD, with a repeat of the course of treatment after 5 days. Patients in group 3 (n = 32) underwent combined treatment: LLLT sessions in the IR spectrum (10 procedures q.o.d.) and a course of Supp. Prostatilen® AC (30 + 180 mg) PR q.h.s. FXD, with a repeat of the course of treatment with peptides according to the same scheme after 5 days. Control examination of patients in all groups was carried out two months after the end of treatment.Results. As a result of treatment of patients in groups 1, 2, and 3, a significant improvement in the main semen parameters, a decrease in the grade of pathological SDNAF, an increase in serum total and free testosterone concentration (p &lt; 0.05) were observed. A comparative statistical analysis of the results obtained in three groups of patients showed that the combined treatment of patients of group 3, who were prescribed a course of LLLT in combination with complex prostate peptides Supp. Prostatilen® AC, was significantly more effective in improving concentration (p &lt; 0.01) and progressive sperm motility (p &lt; 0.01), as well as a decrease in the grade of pathological SDNAF (p &lt; 0.05), than in groups 1 and 2.Conclusion. Combined therapy that includes complex prostate peptides and LLLT in the IR spectrum improves the main semen parameters and reduces the grade of pathological SDNAF in men with idiopathic infertility.

Generation of rf radiation by low-intensity laser pulse trains in air.

In this paper, we analyze and numerically simulate mechanisms for generating directed rf radiation by a low-intensity laser pulse train (LPT) propagating in air. The LPT ionizes the air, forming a plasma filament. The ionization process relies on the background level of radioactivity which plays an important role in initiating a collisional ionization process. In our model a low-intensity LPT photoionizes background negative ions (produced by ambient ionizing radiation) and provides the seed electrons necessary to initiate collisional ionization. The intensity of the LPT is far below tunneling ionization levels. The ponderomotive forces associated with the LPT and self-fields drive plasma oscillations predominately in the radial direction. The driven radial electron currents in turn generate directed rf radiation. As the plasma density builds up on axis, the later portion of the LPT can defocus and limit the interaction length. The spectrum of the rf radiation consists of the fundamental frequency associated with the pulse separation time as well as harmonics. The rf generation mechanism is analyzed using fluid equations which incorporate, among other things, the effects of background radioactivity, photoionization, collisional ionization, ponderomotive and space-charge effects, and electron attachment-recombination processes. As an example, for a specific set of parameters, the rf spectrum and intensity are compared to experimental data.

Boosting of proton beam quality by a pair of low-intensity reverse laser pulses

An attempt has been made to boost the proton beam quality using the multiple counter-propagating laser pulses target interaction with the help of particle-in-cell simulation. Here, we show that a pair of low-intensity reversely incident laser pulses can significantly improve the proton beam quality, i.e., leading to generating a highly peaked monoenergetic proton beam with reduced energy spread. The reverse laser pulses not only help to guide the main laser but also provide initial momentum to the target electrons and thus protons, which is very crucial for efficient acceleration. As a result, a high-quality (sharp narrow peak) monoenergetic proton beam, with energy spectra peaked around GeV, can be obtained for the pulse energies at the level of 50 J. Furthermore, the effects of the time delay for the main laser pulse and the distances between the incident points of the reverse laser pulses are also investigated.

Integrated Dose-Effect Relationship of Near-Infrared Light-Emitting Diode Light on Bone Regeneration in Disuse Osteoporosis Rats.

Objective: To examine the integrated dose-effect relationship of near-infrared (NIR) light-emitting diode (LED) light therapy in promoting bone defect repair in the rat model for osteoporosis (OP). Background: Low-intensity laser therapy has been shown to promote bone regeneration in OP rats. However, its integrated dose-effect relationship is not clear. Methods: Twenty-week-old male Sprague-Dawley rats were randomly assigned to 11 groups: (1) no-treatment control group (C group), (2) tail suspension (TS)-induced disuse OP experimental group (TS-OP group), and (3) OP rats with LED light treatment at nine dosages (L1-L9 groups). The tail of the rat was tied and suspended on the beam of the cage to suspend their hind limbs to induce bone loss for 4 or 7 weeks. The rats were then released and returned to their regular positions. An NIR LED at 810 nm was used on the bilateral hind limbs daily for 4 weeks. The C group rats were not given any treatment. The TS-OP group rats were subjected to identical procedures with L groups, with the exception that the light power was not turned on. After the experiment, the dual-energy X-rays or the microcomputed tomography scan analysis was performed to evaluate bone tissue status. Data analysis was done using SPSS and the health scale. Results: The trabecular thickness, trabecular number, bone volume/total volume, and connectivity density of cancellous bone and the biomechanical properties of femur in light groups were significantly increased compared with the TS-OP group, while the trabecular separation and structure model index were significantly decreased. Conclusions: NIR LED light therapy may promote trabecular bone repair of TS-OP rats. Light intensity influences photobiomodulation. In our dose levels, the greater the light intensity, usually the more effective.

Beyond Electroculture: Modeling Possible Effect of Low Intensity Laser Pen to Improve Plant Growth

It is known that in many regions in this earth, there are growing concerns on rice and other crops supply stability, while the water supply for irrigation has become more scarce. Part of the problem is that farm lands have been reallocated to other purposes, including housing etc, and other reasons include the technology on farming was quite in stagnation for years. In this regard, studies have shown beneficial effects of laser technology to boost plant growth and especially during seed formation. In this small experiment, we take a look at modeling of such low intensity laser pen interacting with plant leaf, and then we tried to look at how low intensity laser pen actually can improve leaf textures, etc. Not necessarily increased leaf area is the only concern, as quality of leaf shall be more visible after low intensity laser pen treatment. It is our hope that this experiment can be useful in one or other ways especially in the spirit of Masanobu Fukuoka, the father of natural farming.

Changes in the activity of micromycete endocellular oxidoreductases under the influence of low-frequency pulsed magnetic field and low-intensity laser radiation

This study aims to investigate the effects of low-frequency pulsed magnetic field (1.5 Hz) and low-intensity laser radiation (0.3 and 0.7 W) on the activity of micromycete endocellular oxidoreductases that catalyze biodegradation of industrial materials such as Penicillium cyclopium, Aspergillus niger, and Alternaria alternata. The investigated physical factors had dose-dependent effects on the activity of fungal endocellular oxidoreductases (catalase and peroxidase): increases and decreases in the activities of enzymes have been observed. An increase in the activity of enzymes can contribute to the manifestation of the adaptive properties of fungi against the action of such physical factors as low-intensity laser radiation and magnetic field. A decrease in the activity of endocatalase and endoperoxidase under the influence of these factors may suppress the vital activity of microorganisms.

Changes in the Activity of Micromycete Intracellular Oxidoreductases under the Action of a Low-Frequency Pulsed Magnetic Field and Low-Intensity Laser Radiation

Changes in the Activity of Micromycete Intracellular Oxidoreductases under the Action of a Low-Frequency Pulsed Magnetic Field and Low-Intensity Laser Radiation

USE OF PHOTOBIOMODULATION IN THE TREATMENT OF BREAST POSTPARTUM INTERCURRENCY: INTEGRATIVE REVIEW

Objective: To analyze the evidence available in the literature about the use of photobiomodulation in the treatment of breast complications in the postpartum. Method: Integrative review of manuscripts in National Library of Medicine National Institutes of Health (PubMed), Web of Science, Latin American and Caribbean Health Sciences Literature (LILACS), Cumulative Index to Nursing and Allied Health Literature (CINAHL), EMBASE, and Scopus databases. Original articles written in Portuguese and English were included, analyzed according to the level of evidence and methodological quality. Results: The sample consisted of five articles. Based on the analysis of the results, three thematic categories were created: types of photobiomodulator used in breast complications, effects of photobiomodulators on healing of breast complications, and effects of photobiomodulators on reducing nipple pain. Both light-emitting diode (LED) and laser photobiomodulators were effective in the treatment of nipple trauma, as the application accelerated the healing process. Low-intensity laser therapy was found to be effective intreating nipple injuries in nursing mothers with pain, providing relief and prolonging exclusive breastfeeding. The single application laser protocol was not effective in reducing pain in women with damaged nipples. Conclusion: This study is an effort to mitigate existing gaps between nursing assistance and research, as it contributes to care based on evidence-based practice.

Correlation of low-intensity laser irradiation and rate of orthodontic tooth movement — a prospective clinical study

Correlation of low-intensity laser irradiation and rate of orthodontic tooth movement — a prospective clinical study