Long-term care work is known for its difficult working conditions, with potential implications for workers’ well being. In England, long-term care policies are moving progressively towards marketisation, while public social care funding is under considerable strain. Little evidence exists on the job demand and control of long-term care workers who provide personal and direct care to adults and older people. The article uses survey data from long-term care workers in England (n = 991) to examine the levels of, and differentials in, job strain among long-term care workers. The findings highlight the vulnerability of certain groups of workers, with potential negative impacts on their well being.