Grape pomace as a natural preservative: Metabolomics insights into lipid oxidation inhibition and flavor stability in beef.

Synergistic inhibition of lipid and protein oxidation in refrigerated pork by a chitosan-based composite film incorporated with ZnO and lysine-modified walnut melanin.

• Curcumin oleogels suppressed AGEs and 5-HMF formation during frying. • β-sitosterol/γ-oryzanol oleogels enhanced moisture and oxidative stability. • Curcumin delivery via oleogels improved texture and color of fried chicken. • Antioxidant oleogel coatings preserved sensory quality of fried chicken. This study evaluated curcumin-enriched oleogel coatings structured with β-sitosterol and γ-oryzanol in rice bran oil for mitigating heat-induced toxic compound formation and improving the quality of deep-fried chicken nuggets. Nuggets coated with oleogels containing 0.1–0.5 g curcumin/100 g oleogel were compared with uncoated controls. The highest curcumin treatment (0.5 g/100 g) reduced fat content by over 50% and increased moisture retention from 48.28% (control) to 60.13% (p < 0.05). Lipid oxidation was significantly inhibited, with TBARS decreasing from 4.12 to 1.07 mg MDA/kg. Heat-induced toxicants were markedly reduced; 5-hydroxymethylfurfural decreased to 29.11 mg/100 g, while advanced glycation end products were minimized, with Nε-(carboxymethyl) lysine and Nε-(carboxyethyl) lysine reduced to 1.50 and 1.11 µg/g, respectively (p < 0.05). Coated samples exhibited lighter color (L* increased from 31.43 to 57.21), reduced crust hardness (puncture force decreased from 12.32 to ∼3.5 N), and improved sensory acceptability (scores > 7). These results demonstrate that β-sitosterol/γ-oryzanol oleogels serve as an effective delivery system for curcumin, simultaneously reducing fat, oxidative degradation, and toxic compounds while preserving sensory quality in fried chicken products.

Flavor fingerprinting and aroma-active compound evolution in prune preserves: Comparative analysis of drying technologies by GC-MS and GC-IMS.

Fat composition and lipid oxidation in raw and cooked minced meat and skin of spent laying and broiler ducks

Application of rice wine lees in enhancing beef jerky quality: synergistic improvement of microbial community succession, flavor characteristics and texture.

Refrigeration-reheating induced fishy odor in cooked Chinese mitten crab (Eriocheir sinensis): Formation and intrinsic factors.

Fueling the fatal voyage: How metabolic plasticity empowers every step of cancer metastasis.

Effects of pre-conditioning combined with innovative grilling processes on myofibrillar protein microstructure, volatilome shifting, and heterocyclic amine formation in duck meat.

Orally engineered liver-targeted garlic exosome-like nanovesicles for astaxanthin precise delivery against alcoholic liver disease in mice.

Ferroptosis-driven coronary plaque vulnerability: A tandem mechanism involving endothelial cells, macrophages, and smooth muscle cells.

Acrylamide is a food contaminant formed via the Maillard reaction that may impair cardiometabolic health. Considering its role in oxidative stress, lipid peroxidation, and adipogenesis, acrylamide may compromise lipid and glucose profiles. The present study aims to assess acrylamide dietary exposure and test longitudinal associations with cardiometabolic outcomes from childhood to adolescence. From G21-birth-cohort, 3138 participants with at least 2 consecutive follow-ups from 4 to 13 years of age were included. Acrylamide dietary exposure was estimated using 3-day food diaries and occurrence data of acrylamide in food. Children presented a higher dietary acrylamide exposure than adolescents. The median exposure was, respectively, 0.79 µg/kg/d at 4 years and 0.44 µg/kg/d at 13 years. Both children (MOE = 215) and adolescents (MOE = 386) exposure levels presented health concerns regarding neoplastic effects. Cross-sectional and longitudinally, acrylamide dietary exposure was positively associated with blood glucose, waist circumference, and fat mass percentage. A negative association was found between dietary acrylamide exposure and z-BMI and cholesterol. This variability suggests that the effects of dietary acrylamide exposure on cardiometabolic health are complex and multifactorial. It was not possible to conclude, without uncertainty, that dietary acrylamide exposure is responsible for abnormalities in cardiometabolic outcomes from childhood to adolescence.

ZFP36 inhibits trophoblast ferroptosis and attenuates preeclampsia development by promoting NCOA4 mRNA degradation and suppressing ferritinophagy.

Barium (Ba) is a non-essential trace element increasingly detected in coastal ecosystems, yet its sublethal effects on marine invertebrates remain poorly characterized. This study investigated the biochemical and mechanistic responses of the shrimp Palaemon adspersus to barium chloride (BaCl2) using an integrated dose-response and modeling framework. Shrimps were exposed for five days (0, 20, 40 and 80mg/L), and hepatopancreas biomarkers were quantified: oxidative stress (H2O2, LOOH, MDA), protein oxidation (PCO, AOPP), antioxidant defenses (SOD, CAT, GPx, GST, GSH, MTs, Vit C, FRAP), neurotoxicity (AChE), and fatty acid composition (SFA, MUFA, PUFA; n-3/n-6). Ba bioaccumulated dose-dependently and was associated with increased oxidative and lipid peroxidation damage, coordinated but ultimately insufficient antioxidant activation, AChE inhibition, and shifts in fatty acids consistent with peroxidation-driven membrane remodeling. Benchmark Dose (BMD) modeling identified LOOH and AChE as the most sensitive endpoints (BMDL=1.49 and 1.73mg/L), while higher BMDL values for antioxidant enzymes indicated later compensatory responses. EC50 analysis corroborated this ranking, confirming oxidative stress and cholinergic disruption as early biomarkers of Ba toxicity. Partial Least Squares Path Modeling (PLS-PM) showed that oxidative damage is the central driver linking antioxidant activation, fatty-acid remodeling, and AChE inhibition (GoF=0.92), supporting a mechanistic cascade from mitochondrial ROS overproduction to membrane damage and neurofunctional impairment. Altogether, this work establishes oxidative stress-mediated toxicity as the primary pathway of Ba in P. adspersus, highlights fatty-acid composition as an integrative endpoint, and validates this species as a sensitive sentinel for biomonitoring trace-metal impacts in coastal and lagoon systems.

Astaxanthin-loaded chitosan nanoparticles attenuate chlorpyrifos-induced nephrotoxicity via activation of the Nrf2/HO-1 axis and suppression of oxidative, inflammatory, and apoptotic pathways.

Polygonatum sibiricum polysaccharides ameliorate diabetes-induced vascular endothelial injury partly through Nrf2/GPX4 activation.

Zein/chitosan nanocomplexes loaded with polyphenols from Polygonatum cyrtonema Hua improve Pickering emulsion stability and β-carotene protection

Effects of lipid oxidation on the deterioration of corn during high-temperature storage: Integration of lipidomics and volatile flavor compound profiling.

Single-cell and metabolomic profiling reveals multi-lineage hepatic perturbations and metabolic reprogramming in pregnant mice exposed to dimethomorph

Dehydration-induced changes in physical and volatile characteristics of house cricket (Acheta domesticus) powder