Body Fat Levels Research Articles

Body Image, Body Composition, and Aging in Women: Insights into an Older Adult Problem

Body image is understudied in aging women. The present perspective article reviews body image, body composition, and aging in women. Sarcopenia, a condition of low muscle mass, is associated with aging, and sarcopenia in combination with excessive body fat causes sarcopenic obesity. Findings of improved health in people with a higher body mass index, known as the obesity paradox, are due to misclassifying healthy people as overweight according to height and body weight instead of according to fat mass and fat-free mass. Body fat infiltrates internal organs in aging adults as increasing levels of body fat are redistributed into the trunk, especially in the abdomen, while subcutaneous fat in the appendages decreases. Accuracy of body image perceptions can determine an individual’s control of body weight. Aging women can protect against sarcopenic obesity by increasing fat-free mass with resistance training and by lowering body fat levels with weight management knowledge and skills. Healthy dietary patterns are low in ultra-processed foods that stimulate excessive consumption of calories and increase body fat levels. In combination with the phosphate additives in ultra-processed food which increase sarcopenia and aging, the present article proposes an etiological pathway in which ultra-processed food consumption eventually leads to aging-related sarcopenic obesity.

Postweaning cafeteria diet induces a short-term metabolic disfunction and a differential vulnerability to develop anxiety-like and depressive-like behaviors in male but not female rats.

Children and adolescents are high consumers of Western diets (rich in fat and sugars), which is a risk factor for overweight and obesity. Moreover, the presence of anxiety and depression among this population has increased significantly. This study explores in young postweaning rats the association between Western diet consumption and the development of metabolic and behavioral disturbances. At postnatal day (PN) 24,Wistarratsof both sexes were weaned and assigned to a control or cafeteria diet (CAF) group. After short-term exposure, a group of rats was euthanized at PN31 to obtain abdominal fat pads and blood samples. Another group of rats was tested in the open-field test, splash test, anhedonia test, and social play across 11days (PN32-42). The CAF groups exhibited a significantly high level of body fat, serum glucose, triglycerides, leptin, and HOMA index when compared to the control groups. Only CAF males exhibited anxiety-like and depression-like behavior. Present results indicate that postweaning short-term exposure to a CAF diet has immediate detrimental effects on metabolism in both sexes. However, only CAF males showed mood disturbances. This study provides evidence that a CAF diet exerts immediate effects on behavior and metabolism in the postweaning period and that sexes present differential vulnerability.

Hubungan Status Gizi, Persen Lemak Tubuh, dan Kadar Hemoglobin Terhadap Kualitas VO2 Maks Siswa Sekolah Sepak Bola Sport Supaya Sehat Semarang

Background: Have a good nutritional status, ideal body fat percentage and normal hemoglobin levels are needed for maintain physical endurance, physical fitness and help to improve the performance of football athletes. When the nutritional status and body fat levels are not ideal, it will interfere athlete mobility. Low hemoglobin levels could disrupt the metabolism of energy that can make an athlete have downgrade quality. Purpose: Know the relationship of nutritional status, body fat percentage, and hemoglobinlevels on the quality of VO2 max student levels from Sport Supaya Sehat (SSS) football school Semarang. Methods: This research was conducted with a cross sectional design at Sport Supaya Sehat (SSS) football school Semarang. All population is a sample which is has 56 respondent. Themeasured data are nutritional status was assessed with body mass index by age, body fat percentage was assessed using Bioelectrical Impedance Analysis, hemoglobin levels was measured using Easytouch GCHb tools and cardiorespiratory endurance was assessed using Yo-Yo test method. Bivariate analysis used Gamma test. Result: The majority characteristics of respondents are have a good nutritional status(69,6%), moderate fat percentages(62,5%), normal hemoglobin levels(71,4%), and good quality of VO2 max levels(55,4%). Bivariate analitical result are nutritional status and body fat percentage has no significant relationship with VO2 max quality levels (p>0,05). Hemoglobin level has significant relationship with VO2 max quality levels (p<0,05). Conclusion: There is a significant relationship between hemoglobin levels with VO2 max quality levels.Key words: Nutritional status; body fat percentage; hemoglobin; VO2 max

Effects of different weight loss dietary interventions on body mass index and glucose and lipid metabolism in obese patients.

To investigate the effects of different weight loss interventions on body mass index (BMI) and glucose and lipid metabolism in obese patients. Obese patients (n = 135) admitted to our hospital between December 2020 and August 2022 were divided into 3 groups, according to their diet patterns: calorie-restricted diet (CRD) group (n = 39), high-protein diet (HPD) group (n = 28), and 5 + 2 intermittent fasting (IF) group (n = 68). Body weight, body fat rate, BMI, hip circumference, and waist circumference were measured before and 60 days after implementation of the respective diet plan. Glycosylated hemoglobin (HbA1c), fasting blood glucose (FBG), 2h postprandial blood glucose (2hPG), triglyceride (TG), total cholesterol, low-density lipoprotein, high-density lipoprotein, and adverse events were evaluated. Following the dietary intervention, the weight (P = .005 for CRD, P < .001 for HPD, and P = .001 for IF), body fat rate (P = .027 for CRD, P = .002 for HPD, and P = .011 for IF group), BMI (P = .017 for CRD, P < .001 for HPD, and P = .002 for IF group), hip circumference (P < .001 for CRD, P = .013 for HPD, and P = .032 for IF group), waist circumference (P = .005 for CRD, P < .001 for HPD, and P = .028 for IF group), HbA1c (P = .014 for CRD, P = .002 for HPD, and P = .029 for IF group), FBG (P = .017 for CRD, P < .001 for HPD, and P = .033 for IF group), and 2hPG (P = .009 for CRD, P = .001 for HPD, and P = .012 for IF group), were significantly decreased. TG (P = .007 for CRD, P < .001 for HPD, and P = .018 for IF group), TC (P = .029 for CRD, P = .013 for HPD, and P = .041 for IF group), LDL-C (P = .033 for CRD, P = .021 for HPD, and P = .042 for IF group), and LDL-C (P = .011 for CRD, P < .001 for HPD, and P = .027 for IF group) improved significantly in the 3 groups, when compared to that before treatment. The HPD had the best effect on reducing blood lipids, followed by the CRD; the effect of IF was slightly lesser. Short-term HPD, CRD, and IF can reduce the weight and body fat of overweight/obese individuals and improve blood lipid and blood sugar levels. The effect of HPD on weight loss, body fat, and blood lipid levels was greater than that of CRD or IF.

Insecticidal Mechanism of Botanical Crude Extracts and Their Silver Nanoliquids on Phenacoccus solenopsis.

In recent years, intensive studies have been carried out on the management of agricultural insect pests using botanical insecticides in order to decrease the associated environmental hazards. Many studies have tested and characterized the toxic action of plant extracts. Four plant extracts (Justicia adhatoda, Ipomea carnea, Pongamia glabra, and Annona squamosa) containing silver nanoparticles (AgNPs) were studied for their effects on Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae) using the leaf dip method. The effects were estimated based on assays of hydrolytic enzyme (amylase, protease, lipase, acid phosphatase, glycosidase, trehalase, phospholipase A2, and invertase) and detoxification enzyme (esterase and lactate dehydrogenase) levels; macromolecular content (total body protein, carbohydrate, and lipid); and protein profile. The results show that the total body of P. solenopsis contains trypsin, pepsin, invertase, lipase, and amylase, whereas J. adathoda and I. carnea aqueous extracts considerably decreased the protease and phospholipase A2 levels, and A. squamosa aqueous extract dramatically increased the trehalase level in a dose-dependent manner. The enzyme levels were dramatically decreased by P. glabura-AgNPs (invertase, protease, trehalase, lipase, and phospholipase A2); I. carnea-AgNPs (invertase, lipase, and phospholipase A2); A. squamosa-AgNPs (protease, phospholipase A2); and J. adathoda-AgNPs (protease, lipase, and acid phosphatase). Plant extracts and their AgNPs significantly reduced P. solenopsis esterase and lactate dehydrogenase levels in a dose-dependent manner. At higher concentrations (10%), all of the investigated plants and their AgNPs consistently decreased the total body carbohydrate, protein, and fat levels. It is clear that the plant extracts, either crude or together with AgNPs, may result in the insects having inadequate nutritional capacity, which will impact on all critical actions of the affected hydrolytic and detoxication enzymes.

Assessment of macronutrients dietary intake, central adiposity among pre- and postmenopausal Egyptian women with benign and malignant breast tumors

Breast cancer (BC) is the second most frequent cancer in women and the second most common cancer worldwide. Lifestyle factors, like body weight, physical activity and diet, may be accompanying with higher BC risk. The assessment of macronutrients dietary intake; protein, fat, carbohydrates and their components of amino, fatty acids, and central obesity/adiposity among pre- and postmenopausal Egyptian women with benign and malignant breast tumors. The current case control study included 222 women: 85 control, 54 benign and 83 breast cancer patients. Clinical, anthropocentric and biomedical examinations were performed. Dietary history and health attitude were done. The anthropometric parameters including waist circumference (WC) and the body mass index (BMI) of the benign and the women with malignant breast lesions showed the highest values when compared to the control (35.45±15.58km2 and 101.24±15.01cm, 31.39±6.77km2 and 98.85±13.53cm and 27.51±7.10km2 and 84.33±13.78cm). The biochemical parameters revealed high concentration of the total cholesterol (TC) (192.83±41.54mg/dl), low density lipoprotein-cholesterol (LDL-C) (117.88±35.18mg/dl) and the median insulin level 13.8 (10.2-24.1) μu/ml in the malignant patients with high significant difference compared to the control. The malignant patients had the highest daily caloric intake (795.84±519.95K calories) proteins (65.39±28.77g), total fats (69.09±32.15g) and carbohydrates (196.70±85.35g), when compared to the control. Data also revealed the high daily consumption of the different types of the fatty acids with high linoleic/linoleinic ratio among the malignant group (14.284±6.25). Branched chain amino acids (BGAAs), sulphur amino acids (SAAs), conditional amino acids (CAAs) and aromatic amino acids (AAAs) proved to be the highest in this group. Correlation coefficient between the risk factors revealed either positive or negative weak correlation except that between serum LDL-C concentration and the amino acids (isoleucine, valine cysteine, tryptophan and tyrosine) and negative association with the protective polyunsaturated fatty acids. Participants with breast cancer had the greatest levels of body fatness and unhealthy feeding habits relative to their high calorie, protein, carbohydrate, and fat intake.

The Effect of Physical Activities on Somatic Parameters of Masaryk University Students – Some Selected Results

Purpose: The current trend is an increasing sedentary lifestyle in all age categories. Among university students, there is an alarming decline in physical activity while increasing the percentage of total body fat compared to high school students. The main goal of the study is to describe the current state of body composition of university students and to assess the impact of physical activity/inactivity in this specific age group, which has changed very dynamically in recent years due to the coronavirus pandemic. Methods: A total of 358 probands with a mean age of 20.87 ± 1.43 years were involved in the research, of which 234 women (65.4%) had a height of 167.9 ± 6.3 cm and a body weight of 61.3 ± 10.0 kg, BMI 21.7 ± 3.2, body fat 25.9 ± 6.4%, skeletal muscle mass 24.7 ± 3.3% and 124 men (34.6%) with body height 180.9 ± 7.7 cm, body weight 77.6 ± 12.4 kg, BMI 23.6 ± 2.8, body fat 15.8 ± 5.4%, skeletal muscle mass 37.0 ± 5.6%. For the purposes of valid categorization into high active, minimally active, and inactive probands, the International Standardized Physical Activity Questionnaire (IPAQ) was used, which monitors physical activity in the last 7 days. The questionnaire includes questions regarding the frequency and time spent in each intensity of physical activity, as well as the time spent sitting. The non-invasive method of bioelectric tetrapolar impedance using the InBody 230 device was used for the analysis of somatic parameters. The Takei hand dynamometer was used for the diagnosis of muscle strength. Some selected results: According to IPAQ, probands were classified as inactive (16%), minimally active (58%) and high active (25%). The analysis of selected aspects of physical activity shows that men are more active than women, but both sexes spend more than 5.5 hours a day sitting on average. A total of 39% of probands have a higher level of total body fat than the recommended norms. Conclusion: The study showed that lower levels of physical activity are associated with higher values ​of total body fat in university students. At the same time, within our sample both sexes out of 84% comply with general recommendations regarding the volume and intensity of physical activity.

The effect of SGLT2 inhibitors, GLP1 agonists, and their sequential combination on cardiometabolic parameters: A randomized, prospective, intervention study

BackgroundPulse wave velocity (PWV) and augmentation index (AIx) are indices used to assess arterial stiffness. We aim to compare the effect of empagliflozin, liraglutide and their sequential combination on arterial stiffness indices in patients with type 2 diabetes (T2D). MethodsThis was a randomized single blind study evaluating the effect of empagliflozin vs liraglutide in adult patients with T2D. Patients were randomized to liraglutide titrated gradually to 1.8 mg or empagliflozin 25 mg in 1:1 ratio. Three months later empagliflozin was added to the liraglutide group, and liraglutide was added to the empagliflozin group. Patients were assessed with non-invasive tests for arterial stiffness (i.e., carotid-femoral PWV and AIx of aortic pressure) at baseline, 3-month and 9-month visits (final visit was extended for 3 months from the initial design due to Covid 19 pandemic). The primary outcome was the between-group difference of PWV change (ΔPWV) and ΔAIx at 3 months. Secondary outcomes included the between-group difference of ΔPWV and ΔAIx at 9 months, as well as the ΔPWV and ΔAIx between baseline and 9-month visit when total study population was assessed. ResultsA total of 62 patients with T2D (30 started liraglutide; 32 empagliflozin, mean age 63 years, 25 % with established cardiovascular disease) participated in the study. We failed to show any significant between-group differences of ΔPWV and ΔΑΙx at 3 and 9 months, as well as between-group difference of ΔPWV and ΔAIx for the total study population between baseline and 9-month visit. In contrast, systemic vascular resistance and lipoprotein(a) levels improved, showing better results with liraglutide than empagliflozin. Favorable effects were also observed on body weight, body mass index, body and visceral fat, blood pressure, HbA1c, and uric acid levels. ConclusionNo evidence of a favorable change in arterial stiffness indices was seen with empagliflozin or liraglutide or their combination in this study. Well-designed powerful studies are needed to address any potential effects on arterial stiffness in selected populations.

Clinical Study of Metabolic Parameters, Leptin and the SGLT2 Inhibitor Empagliflozin among Patients with Obesity and Type 2 Diabetes.

Obesity is a major public health problem worldwide, and it is associated with many diseases and abnormalities, most importantly, type 2 diabetes. The visceral adipose tissue produces an immense variety of adipokines. Leptin is the first identified adipokine which plays a crucial role in the regulation of food intake and metabolism. Sodium glucose co-transport 2 inhibitors are potent antihyperglycemic drugs with various beneficial systemic effects. We aimed to investigate the metabolic state and leptin level among patients with obesity and type 2 diabetes mellitus, and the effect of empagliflozin upon these parameters. We recruited 102 patients into our clinical study, then we performed anthropometric, laboratory, and immunoassay tests. Body mass index, body fat, visceral fat, urea nitrogen, creatinine, and leptin levels were significantly lower in the empagliflozin treated group when compared to obese and diabetic patients receiving conventional antidiabetic treatments. Interestingly, leptin was increased not only among obese patients but in type 2 diabetic patients as well. Body mass index, body fat, and visceral fat percentages were lower, and renal function was preserved in patients receiving empagliflozin treatment. In addition to the known beneficial effects of empagliflozin regarding the cardio-metabolic and renal systems, it may also influence leptin resistance.

Clinical observation of Febuxostat in the treatment of gout patients with different body fat levels.

Clinical observation of Febuxostat in the treatment of gout patients with different body fat levels.

Application of Caenorhabditis elegans in Lipid Metabolism Research.

Over the last decade, the development and prevalence of obesity have posed a serious public health risk, which has prompted studies on the regulation of adiposity. With the ease of genetic manipulation, the diversity of the methods for characterizing body fat levels, and the observability of feeding behavior, Caenorhabditis elegans (C. elegans) is considered an excellent model for exploring energy homeostasis and the regulation of the cellular fat storage. In addition, the homology with mammals in the genes related to the lipid metabolism allows many aspects of lipid modulation by the regulators of the central nervous system to be conserved in this ideal model organism. In recent years, as the complex network of genes that maintain an energy balance has been gradually expanded and refined, the regulatory mechanisms of lipid storage have become clearer. Furthermore, the development of methods and devices to assess the lipid levels has become a powerful tool for studies in lipid droplet biology and the regulation of the nematode lipid metabolism. Herein, based on the rapid progress of C. elegans lipid metabolism-related studies, this review outlined the lipid metabolic processes, the major signaling pathways of fat storage regulation, and the primary experimental methods to assess the lipid content in nematodes. Therefore, this model system holds great promise for facilitating the understanding, management, and therapies of human obesity and other metabolism-related diseases.

Assessment of the obesity based on voice perception

Human voice is an extremely important biological signal which contains information about sex, age, emotional state, health and physical features of a speaker. Estimating a physical appearance from a vocal cue can be an important asset for sciences including forensics and dietetics. Although there have been several studies focused on the relationships between vocal parameters and ratings of height, weight, age and musculature of a speaker, to our knowledge, there has not been a study examining the assessment of one’s BMI based on voice alone. The purpose of the current study was to determine the ability of female “Judges” to evaluate speakers’ (men and women) obesity and body fat distribution from their vocal cues. It has also been checked which voice parameters are key vocal cues in this assessment. The study material consisted of 12 adult speakers’ (6 women) voice recordings assessed by 87 “Judges” based on a 5-point graphic scale presenting body fat level and distribution (separately for men and women). For each speaker body height, weight, BMI, Visceral Fat Level (VFL, InBody 270) and acoustic parameters were measured. In addition, the accuracy of BMI category was verified. This study also aimed to determine which vocal parameters were cues for the assessment for men and women. To achieve it, two independent experiments were conducted: I: “Judges” had to choose one (obese) speaker from 3 voices (in 4 series); II: they were asked to rate body fat level of the same 12 speakers based on 5-point graphic scale. Obese speakers (i.e., BMI above 30) were selected correctly with the accuracy greater than predicted by chance (experiment I). By using a graphic scale, our study found that speakers exhibiting higher BMI were rated as fatter (experiment II). For male speakers the most important vocal predictors of the BMI were harmonics-to-noise ratio (HNR) and formant dispersion (Df); for women: formant spacing (Pf) and intensity (loudness). Human voice contains information about one’s increased BMI level which are hidden in some vocal cues.

Genetic and phenotypic relationships between ewe reproductive performance and wool and growth traits in Uruguayan Ultrafine Merino sheep.

This study reports genetic parameters for yearling and adult wool and growth traits, and ewe reproductive performance. Data were sourced from an Uruguayan Merino flock involved in a long-term selection program focused on reduced fiber diameter (FD), and increased clean fleece weight (CFW) and live weight (LW). Pedigree and performance data from approximately 5,700 mixed-sex yearling lambs and 2,000 mixed-age ewes born between 1999 and 2019 were analyzed. The number of records ranged from 1,267 to 5,738 for yearling traits, and from 1,931 to 7,079 for ewe productive and reproductive performance. Data on yearling and adult wool traits, LW and body condition score (BCS), yearling eye muscle area (Y_EMA), and fat thickness (Y_FAT), and several reproduction traits were analyzed. The genetic relationships between FD and reproduction traits were not different from zero. Moderate unfavorable genetic correlations were found between adult CFW and ewe lifetime reproduction traits (-0.34 ± 0.08 and -0.33 ± 0.09 for the total number of lambs weaned and total lamb LW at weaning, respectively). There were moderate to strong positive genetic correlations between yearling LW and all reproduction traits other than ewe-rearing ability (-0.08 ± 0.11) and pregnancy rate (0.18 ± 0.08). The genetic correlations between Y_EMA and reproduction traits were positive and ranged from 0.15 to 0.49. Moderate unfavorable genetic correlations were observed between yearling FD and Y_FAT and between adult FD and BCS at mating (0.31 ± 0.12 and 0.23 ± 0.07, respectively). The genetic correlations between adult fleece weight and ewe BCS at different stages of the cycle were negative, but generally not different from zero. This study shows that selection for reduced FD is unlikely to have any effect on reproduction traits. Selection for increased yearling LW and Y_EMA will improve ewe reproductive performance. On the other hand, selection for increased adult CFW will reduce ewe reproductive performance, whereas selection for reduced FD will negatively impact body fat levels. Although unfavorable genetic relationships between wool traits and both FAT and ewe reproductive performance existed, simultaneous improvements in the traits would occur using appropriately designed indexes.

Patterns of eating habits and body composition in primary school children

The study of the influence of nutrition and its associations with other parameters, which are closely related to the metabolic profile, in order to better understand the mechanisms of realization of the obesity phenotype in the child population is of particular interest. The aim of the study was to investigate the eating habits of elementary school children and their dependence on the parameters of physical development and body composition of the child population of Tomsk. Material and methods. 506 children aged 7 to 12 years were examined. The main group consisted of 216 children (53.1% boys, 46.9% girls) with overweight and obesity, the control group - 290 healthy children (49.0% boys, 51.0% girls). All children underwent measurement of anthropometric parameters with the calculation of SDS body mass index (WHO Anthro Plus), estimation of body composition by bioimpedancemetry. The actual nutrition of schoolchildren was assessed by the frequency method using a questionnaire. Results. Overweight and obese children had levels of body fat, percent body fat, visceral fat area and whole-body phase angle which were statistically significantly (p<0.001) higher in comparison with the control group. Regular meals were more typical for schoolchildren of the control group compared to the main group (p=0.002). A survey of parents showed that 55.0% of them don't have problems with the nutrition of their children, 32.0% do not have conditions for monitoring their nutrition, 37.5% of children consume high-calorie foods, 29.0% do not comply with the diet, 64.5% - eat while watching TV. Only 21.1% of children consume fresh vegetables daily, cereals - 21.8%, dairy products - 30.3%, milk - 56.5%, meat - 58.5%, cottage cheese - 10.3%. Fish is not consumed by 25.6% of children, consumed less than once a week - by 47.2%. Several times a week, sausages and sausages are consumed by 41.7% of schoolchildren, confectionery - by 32.5%, chocolate and sweets - by 51.5%. Conclusion. The food habits of primary school students in Tomsk are characterized by an insufficient amount of vegetables and fruits, dairy products, fish dishes, a high level of consumption of ultra-processed red meat and various confectionery products (sweets, chocolate, cakes). The absence of statistically significant differences in the results of the survey between the control group and the main group may be due to the multifactorial nature of obesity associated with a variety of behavioral, biological and social factors, the real contribution of which remains to be determined.

Which anthropometric equation to predict body fat percentage is more strongly associated with maximum oxygen uptake in adolescents? A cross-sectional study.

Identifying the relationship between maximum consumption of oxygen and body fat percentage is important due to increased cardiovascular risk factors. This study aimed to verify the association between body fat percentage determined by three predictive equations using anthropometric measures (Lohman, Boileau, and Slaughter) and maximum oxygen uptake (VO2max). We also aimed to estimate the capacity of these equations for explaining VO2max variations in adolescents according to sex. This was a cross-sectional study conducted in high schools in São José, Southern Brazil. This study included 879 adolescents (14-19 years) from Southern Brazil. Aerobic fitness was assessed using the modified Canadian Aerobic Fitness Test. The independent variable was body fat percentage predicted by the Lohman, Boileau, and Slaughter equations. Analyses adjusted for sociodemographic variables, physical activity level, and sexual maturation were performed with P value < 0.05. All anthropometric prediction equations used to estimate body fat percentage explained VO2max variations in adolescents. In male adolescents, both regression models based on the Boileau et al.12 and Lohman10 equations revealed higher explanatory power for VO2max (20%) compared with that based on the Slaughter et al.13 equation (19%). In female adolescents, the model based on the anthropometric equation of Slaughter et al.13 showed the greatest explanatory power for VO2max (18%). The inverse relationship between VO2max and body fat intensifies the need for effective intervention programs that prioritize maintenance of appropriate body fat and aerobic fitness levels because inadequate levels of both factors result in negative health consequences.

The effects of dietary self-monitoring intervention on anthropometric and metabolic changes via a mobile application or paper-based diary: a randomized trial.

Weight loss via a mobile application (App) or a paper-based diary (Paper) may confer favorable metabolic and anthropometric changes. A randomized parallel trial was conducted among 57 adults whose body mass indices (BMIs) were 25 kg/m2 or greater. Participants randomly assigned to either the App group (n = 30) or the Paper group (n = 27) were advised to record their foods and supplements through App or Paper during the 12-week intervention period. Relative changes of anthropometries and biomarker levels were compared between the 2 intervention groups. Untargeted metabolic profiling was identified to discriminate metabolic profiles. Out of the 57 participants, 54 participants completed the trial. Changes in body weight and BMI were not significantly different between the 2 groups (P = 0.11). However, body fat and low-density lipoprotein (LDL)-cholesterol levels increased in the App group but decreased in the Paper group, and the difference was statistically significant (P = 0.03 for body fat and 0.02 for LDL-cholesterol). In the metabolomics analysis, decreases in methylglyoxal and (S)-malate in pyruvate metabolism and phosphatidylcholine (lecithin) in linoleic acid metabolism from pre- to post-intervention were observed in the Paper group. In the 12-week randomized parallel trial of weight loss through a App or a Paper, we found no significant difference in change in BMI or weight between the App and Paper groups, but improvement in body fatness and LDL-cholesterol levels only in the Paper group under the circumstances with minimal contact by dietitians or health care providers. Clinical Research Information Service Identifier: KCT0004226.

Effect of repeated alternative thermal stress on the physiological and body composition characteristics of young women sporadically using sauna

Aim: The aim of this study was to determine the effect of repeated alternative thermal stress on the physiological parameters of young women sporadically used sauna. Materials and method: Twenty young women (age: 24.2±2.1 years) were exposed to four sauna sessions of 12 minutes each (temperature: 90-91°C; humidity: 14-16 %) with four 6-minute cool-down breaks including 2-minute cold water immersion (temperature: 9-11oC). Physiological characteristics were monitored before and after the 72-minute experiment. Systolic and diastolic blood pressures (systolic - SBP, diastolic - DBP), heart rate (HR), forehead temperature, and body composition were determined on each subject and dependent t-test were performed on each variable. Results: During the 72-minute experiment forehead temperature increased significantly (p&lt;0.001). A significant decrease was observed in DBP (p=0.045), body mass (p&lt;0.001), minerals (p=0.01), body fat mass (p=0.035), BMI (p&lt;0.001), waist to hip ratio (p=0.042), visceral fat level (p=0.004) and obesity degree (p=0.044) during four successive 12-minute sauna sessions. Conclusions: Seventy-two minutes of alternating (hot and cold) repeated thermal stress has a significant effect on significant decrease in the values of DBP, and body composition (body mass, BMI, BFM and minerals) characteristics. Two-minute cold water immersions allow the body to cool down significantly and gives the opportunity to stay in the sauna for longer time. Long stays in the sauna can be used to reduce levels of body fat in the human body.

Visceral Adiposity Index as an Indicator of Cardiometabolic Risk in Patients with Congenital Adrenal Hyperplasia.

Aim: To evaluate the cardiometabolic risk in patients with CAH (21 (OH) enzyme deficiency) on the basis of the visceral adiposity index (VAI), which indicates dysfunction of the visceral adipose tissue (VAT). Materials and Methods: A total of 41 patients and 38 body mass index (BMI), age, and gender-matched healthy controls (HC) were included. The patients' and HCs' age, gender, waist circumference (WC), BMI information and total cholesterol (TC), high-density lipoprotein (HDL), triglyceride (TG) values, smoking, and medication history were obtained from medical charts. Weight, height, WC, and blood pressure levels were measured. Patients' and HCs' BMI, Framingham risk scores (FRS), VAI and Ferriman-Gallwey scores were calculated. The patients' and HCs' age, gender TC, HDL, and TG, androstenedione, dehydroepiandrosterone sulfate (DHEASO4), 17 hydroxyprogesterone (17(OH)P) values, smoking, and medication history were obtained from medical charts. Body fat and muscle mass levels were measured with Tanita T 6360. Results: Gender distribution, mean age, and BMI of patients with CAH were 34/7, 30 ± 8, 27 ± 5.4; HC subjects 30/8, 30 ± 6, 27 ± 3.8 (P = 0.9, 0.6, 0.9, respectively). The VAI values of patients with a diagnosis of CAH 3.7 (2.3-6.9) were found to be significantly higher than those of HC patients 2.5 (1.8-3.9; P = 0.02). The mean glucocorticoid doses of the patients were 17 ± 9 mg/day. The glucocorticoid dose level was determined as independent risk factor on the FRS (P = 0.03, β = 0.04) and VAI (P = 0.018, β = 0.17). Conclusion: Glucocorticoid dose optimization should be done more carefully to improve metabolic and cardiovascular outcomes in CAH patients.

Changes in Anthropometric Measurements and Physical Fitness of Polish Students in 20-Year Period

Intergenerational changes are still being recorded worldwide, although their magnitude and direction may vary in different countries. The aim of this study was to determine changes in the magnitude and direction of changes in the body morphology and motor abilities of physically active adults over 20 years. Two hundred and fifty-two individuals aged 18-28 years volunteered to participate in the study. The changes were analyzed over a 20-year period (March 2001; P1 vs. March 2022; P2). The measured parameters were body height, weight, and body fat. Further, hand grip strength with dynamometer measurement, a sit-up test, a sit and reach test, and a standing long jump were performed to examine motor abilities. The results of the conducted tests were compared between subjects from both periods. Our study confirms changes in trends concerning body morphology and motor ability performance. Higher values of body mass index and body fat were observed in P2 women, whereas these differences were not significant in men. Additionally, in terms of physical performance, the P2 group noted worse results than their peers from the past. Despite young adults claiming to have similar physical activity levels to those observed in the past, they demonstrate poorer physical performance and higher body fat levels. The observed changes can be considered negative.

Saturated fat from dairy sources is associated with lower cardiometabolic risk in the Framingham Offspring Study

Current dietary guidance recommends limiting intakes of saturated fats, but most fails to consider that saturated fats from different food sources may have different health effects. We aimed to evaluate the associations of saturated fats from dairy and nondairy sources with measures of body fat, inflammatory biomarkers, lipid concentrations, and lipid particle sizes and concentrations. The Framingham Offspring Study is a prospective cohort study. Participants (n=2391) ≥30 y of age who had dietary records and data on the outcomes of interest were included. Among females, those in the highest quintile (compared with the lowest) of dairy-derived saturated fat had lower multivariable-adjusted levels of body fat [BMI (in kg/m2): 26.2 compared with 27.8, P<0.01; and percentage fat mass: 36.7% compared with 38.0%, P=0.09) and larger LDL particle sizes. Nondairy saturated fat in females was inversely associated with the triglyceride (TG):HDL ratio (P=0.03). Among males, intakes of dairy-derived saturated fats were inversely associated with C-reactive protein (P<0.01), fibrinogen (P<0.01), TGs (P<0.01), and the TG:HDL ratio (P<0.01). HDL cholesterol was 2.8mg/dL (P=0.04) higher among males in the highest (compared with the lowest) quintile of saturated fat from dairy sources. Males with the highest intakes of dairy-derived saturated fats had larger HDL and LDL particle sizes (P<0.01 for both), a higher HDL particle concentration (P<0.01), and a lower VLDL particle concentration (P<0.01). There were no statistically significant adverse effects of saturated fats from nondairy sources on any of these outcomes in either males or females. Males with higher intakes of dairy-derived saturated fats had a less atherogenic profile than males with lower intakes of these fats. These effects were weaker in females. Nondairy saturated fats were not associated with these cardiometabolic outcomes.