Left Inguinal Lymph Node Metastasis Research Articles

Clinical Characteristics of Basal Cell Carcinomas of the Scrotum: An Institutional Retrospective Review

Objective. To analyse the clinical and pathologic features, discuss therapeutic strategies, and possibly cause and identify prognostic factors of scrotal basal cell carcinoma (BCC) in Chinese patients. Materials and Methods. Between January 2012 and December 2022, 12 patients with scrotal BCC were diagnosed and treated at our institution. A review was conducted based on the clinical characteristics, pathology slides, and tissues of these patients. Results. The median patient age was 69.26 ± 11.23 years. The skin lesions presented as red papules, blue-grey polypoid nodules, erythematous patches, brownish plaques, and so on. All patients were treated using wide excision, but the margins varied from 0.5 cm to 2 cm. HPV infection was checked in all lesions, with 4 out of 12 testing positive for P16 and 1 for HPV16 DNA. We found mottled positive expression of P16 in the cytoplasm and membrane. One patient developed left inguinal lymph node metastasis and was successfully treated using bilateral inguinal lymphadenectomy. The rest recovered well without relapse. Conclusions. BCC of the scrotum is rare, but long-term surveillance is recommended for BCC patients, and whether genital HPV infection is a noteworthy feature for these patients remains under investigation.

Malignant Melanoma of Left Sole Metastasis to Brain: A Case Report

A 60-year-old man presented with malignant melanoma on left heel with left inguinal lymphnode metastasis. He developed right hemiparesis on the 3rd POD of wide local excision of anulcerated lesion of the left sole. CT scan showed multiple cerebral metastasis in the bothparietal lobes. No neurological features also manifested before operation of the primary lesion.
 Journal of Surgical Sciences (2016) Vol. 20 (1) : 32-33

An Unusual Case of Cervical Cancer with Inguinal Lymph Node Metastasis: A Case Report and Review of the Literature

There is limited data regarding to treatment of cervical cancer patients with isolated non-regional lymph node metastasis. Herein we report a case of cervical cancer with left inguinal lymph node metastasis at the time of diagnosis. A 52-year-old woman referred to gynecologic oncology department with postmenopausal vaginal bleeding history for a year. Gynecological examination revealed a bulky cervical tumor with left parametrial invasion. The biopsy of this lesion revealed a squamous cell carcinoma of the cervix. A pelvic magnetic resonance imaging (MRI) demonstrated a bulky cervical mass with a parametrial extension on left side, in addition to the suspicious lymph nodes in the para-aortic, pelvic and left inguinal chains. The patient was underwent extraperitoneal para-aortic lymph node dissection and left inguinal lymphadenectomy. Histopathological examination of the lymph nodes revealed that there were metastatic lymph nodes in the para-ortic, and left inguinal chains. We planned neoadjuvant chemotherapy consisting of paclitaxel and carboplatin; and we decided to plan adjuvant treatment with respect to the treatment response to the induction chemotherapy. The control computed tomography after 6 cycle of chemotherapy showed that there was a good-partial response; therefore definitive radiotherapy was planned. A month after the radiotherapy pelvic MRI was performed and it showed a complete response. After 38 months of follow-up the patient admitted to the emergency department with ileus. The patient developed sepsis and forty months after the completion of the radiotherapy the patient expired because of septic shock.

人工肛門部に発生し左鼠径リンパ節転移を伴った異時性多発大腸癌の1例

人工肛門部に発生し左鼠径リンパ節転移を伴った異時性多発大腸癌の1例

Basal Cell Carcinoma of the Scrotum: Clinicopathologic Analysis of 10 Cases

Basal cell carcinoma (BCC) located on the scrotum is rare. To analyze clinical and pathologic features, discuss therapeutic strategies, and identify prognostic factors of scrotal BCC in Chinese patients. Between 2000 and 2010, 10 patients with scrotal BCC were diagnosed and treated at our institution. A review was performed using the clinical records and dermatopathologic slides of these patients. The median patient age was 70. Skin lesions presented as red nodules and brownish plaques. All patients were treated using wide excision without adjuvant therapy. After an average follow-up of 47months, eight patients were in good health without any relapse. One patient developed left inguinal lymph node metastasis at 21months that was successfully treated using bilateral inguinal lymphadenectomy. One patient developed bilateral pulmonary metastasis at 48months and was palliatively treated with chemotherapy. The clinical and histopathologic risk factors predisposing to metastasis were large primary neoplasms; a long period of misdiagnosis; and infiltrating, morpheaform, spiky, irregular outline pathologic patterns. BCC of the scrotum is rare. It can metastasize after a long period of initial therapy. Long-term surveillance including a complete metastatic examination is recommended for these patients.

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We report a case of zosteriform and epidermotropic metastasis of a cutaneous squamous cell carcinoma (SCC) . A 72-year-old woman noticed multiple crustic and red papules with zosteriform distribution on the right L1-L3 dermatomes. She had been excised a SCC on the right knee and been dissected right inguinal lymph nodes two years before.The histopathological diagnosis of the papules on the right thigh and hip regions was epidermotropic metastasis of SCC. There were no other metastases, with an exception of left inguinal lymph node metastasis. Multiagent-combinationchemotherapy and radiation therapy were performed on the cutaneous metastatic lesions.Only a few cases of zosteriform and/or epidermotropic metastases of cutaneous SCC have ever been reported. [Skin Cancer (Japan) 2000; 15: 262-265]

Pulmonary adenocarcinoma metastatic to the gingiva

Gingival metastasis from lung cancer is very uncommon. We report a case of distant metastasis of pulmonary adenocarcinoma in the mandibular gingiva. A 54-year-old man was admitted to our hospital on September 1, 1997 with hemoptysis. Right upper lobectomy with mediastinal lymph node dissection was performed on September 16. On the 14th postoperative day, the patient complained of a gingival swelling. In the lower right premolar area, a wide pedunculated mass was seen on the mandibular gingiva. Excisional biopsy of the tumor was performed, and histopathological examination revealed that the tumor was a metastatic lesion from the pulmonary adenocarcinoma. The patient received 46.8 Gy of linac irradiation to the tumor area and the entire oral condition improved markedly. However, bilateral adrenal gland metastases were recognized, and left inguinal lymph node metastasis was detected 2 months after lung resection. He developed tumor metastases to multiple organs and died of respiratory failure on December 12, 1997.