Two dimensional layered double hydroxides augment antigen loading and release.

From rapid reduction to stable immobilization: A regenerative 4D FeMgAl layered double hydroxide-microbial strategy for chromium remediation.

Exploring the frontiers of self-healing layered double hydroxides in corrosion: innovations, challenges, and applications

The electrocatalytic nitrate reduction reaction (NO3RR) efficiently converts nitrate pollutants into valuable ammonia. While layered double hydroxides (LDHs) are promising NO3RR catalysts, their inherent low conductivity and layer stacking hinder performance. Herein, we report a binary-soft-template-mediated colloidal strategy to fabricate monolayer NiMnFe LDH ultrathin nanosheets (UNSs), constructing Fe(OH)3/NiMnFe LDHs heteronanostructures (HNs) via edge-selective growth. This noble-metal-free, loop-sheet catalyst achieves an outstanding ammonia production rate (24.41 mg h-1 cm-2), high selectivity, and long-term durability. These superior catalytic properties are attributed to Fe incorporation, which optimizes the electronic structure and enriches active sites, and the constructed heterointerfaces that facilitate efficient electron transfer. This synthetic strategy provides a robust platform for engineering advanced LDH-based and 2D materials to achieve specific functionalities in nitrate reduction.

Layered double metal hydroxide nanosheets (LDH) delivery ICG for photoimmune antibacterial therapy and tissue infected wound regeneration.

Upcycling PET waste into CoNi-based electrocatalysts for ethylene glycol oxidation integrated with energy-efficient H2 evolution.

Current strategies for metabolic regulation within the tumor microenvironment (TME) often rely on exogenous drugs, leading to transient benefits and necessitating repeated administrations that frequently cause detrimental side effects. To address this, we have developed a novel bacterial biocatalytic reactor, LDGM, which is fabricated by functionalizing Shewanella oneidensis MR-1 (MR-1) bacteria with DOX/GOx-loaded layered double hydroxide (LDH) nanosheets. This sophisticated biomaterial exhibits specific targeting towards hypoxic tumor areas, facilitating the controlled release of doxorubicin (DOX), glucose oxidase (GOx), and Fe3+. Crucially, MR-1 continuously metabolizes intratumoral lactate, thereby augmenting chemotherapy efficacy and combating tumor multidrug resistance. Moreover, with the hypoxic environment generated by GOx and lactate metabolism, MR-1 performs iron respiration, promoting the reduction of Fe3+ through electron transfer to simultaneously induce ferroptosis and apoptosis. Our investigations in murine tumor models showed that LDGM significantly suppresses tumor progression while simultaneously enhancing ferroptosis and apoptosis. Therefore, this living biomaterial presents a promising avenue for advancing cancer therapy by establishing continuous metabolic regulation of the intratumoral lactate/glucose microenvironment.

Ni-Mo bimetallic layered double hydroxide encapsulated ZIF-67 catalyst with nanoflower-like porous structure promotes the activation of calcium sulfite for the degradation of chloroquine phosphate

Magnesium powder explosion suppression: high-performance carbonate-intercalated calcium-iron layered double hydroxide as an advanced suppressant

Layered double hydroxide intimately incorporated into geopolymer matrix: Feasibility study of an all-mineral composite

Investigation of biological pathway of cobalt-55-labeled layered double hydroxide depending on surface charge

Tumor disaggregation sensitizes radio-therapy for low rectal tumor.

Performance evaluation and field validation of a composite VOC inhibitor for asphalt pavement on the Qinghai-Tibet Plateau

Effects of reactive intercalated layered double hydroxides on performance of bio-oil rejuvenated SBS modified asphalt based on aged SBS bridge reconstruction mechanism

Peroxymonosulfate activation by NiCoFe-layered double hydroxides for enhancing contaminant elimination in water.

To achieve trace-level detection of antibiotics in food matrices, a NiFeCo layered double oxide supported N,S co-doped collagen-derived porous carbon (NiFeCo LDO-C) composite was rationally designed by integrating a dynamic metal active-site regeneration mechanism with a self-template/self-etching strategy for highly sensitive and stable electrochemical sensing of nitrofurantoin (NFT). The introduction of Co enables dynamic regeneration of Fe active sites, improving catalytic stability. This template-free strategy exploits the structural evolution of NiFeCo layered double hydroxides (LDH) during calcination: the decomposition process not only defines hierarchical pore channels through self-templating but also collaboratively promotes self-etching of the collagen-derived carbon matrix via the release of gases, enabling precise pore regulation. Benefiting from synergistic effects between heteroatom-doped carbon and mixed-valence Ni/Fe/Co centers, the sensor exhibits a wide linear range (0.05-350 μM), a low detection limit of 5.3 nM, and excellent selectivity. Satisfactory recoveries were obtained in milk and honey samples, while river water analysis further demonstrated broader applicability. Electrochemical analysis indicates that NFT reduction follows an irreversible, diffusion-controlled process. This work offers a promising strategy for developing self-regenerating electrochemical sensors for antibiotic residue detection in food safety monitoring.

Achieving durable oxygen evolution reaction (OER) under industrial alkaline water electrolysis (AWE) conditions remains a formidable challenge, arising from dynamic Fe dissolution and segregation in NiFe layered double hydroxides (LDH) and further aggravated by sluggish ion transport and bubble release at the gas-liquid-solid interface. Herein, we report a design concept of using an ultrathin sodium polyacrylate (PANa) hydrogel layer on NiFe LDH as a spatially confining, transport-permissive interphase to dynamically stabilize Fe sites and enhance multiphase interfacial transport for boosting OER durability in hectowatt-scale AWE. We demonstrate that the PANa interphase converts uncontrolled Fe dissolution-segregation into an interfacially confined and self-regulated dissolution-redeposition process, in which carboxylate-mediated Fe-O-C coordination thermodynamically stabilizes lattice Fe by suppressing overoxidation, while the hydrated polymer network kinetically retains transiently dissolved Fe within the interfacial region and favors its reincorporation toward homogeneous active-phase regeneration. Meanwhile, the carboxylate-rich framework reorganizes the interfacial hydrogen-bond network to accelerate OH- transport and promote rapid O2 disengagement through its porous superaerophobic architecture. In an industrial 600 W-scale alkaline electrolyzer (679 cm2 total anode area), the PANa/NiFe LDH anode sustains stable operation for over 2500 h at 0.5 A cm-2, with an energy consumption as low as 4.25 kWh Nm-3 H2 and a competitively low projected hydrogen production cost of US$ 2.38 kgH2-1.

An ECL immunosensor based on the synergistic self-enhancement of CuCoFe-LDH with Luminol-PEI for ultrasensitive detection of AFP.

Multi-modal sensor based on ANTS/MgFe-LDH nanocomposite combined with machine learning for the intelligent recognition of antioxidants and metal ions.

NiFe-based layered double hydroxides (LDHs), as engineered nanomaterials (ENMs), are widely utilized in industrial applications, environmental remediation, and soil improvement. However, the biological impacts of such ENMs on plant-soil systems remain insufficiently explored. A 50-day soil cultivation experiment was conducted to assess the effects of two-dimensional and three-dimensional NiFe-based LDHs (2D NiFe-LDHs and 3D NiFeS-LDHs) on ryegrass growth and soil ecosystem. Generally, morphology and structure differences influence the biological effects of NiFe-based LDHs. 2D NiFe-LDHs promote ryegrass growth at specific concentrations, whereas 3D NiFeS-LDHs exhibit significant inhibitory effects on ryegrass growth. NiFe-based LDHs directly impacted soil geochemistry. 3D NiFeS-LDHs decreased soil pH while increasing electrical conductivity and soil organic carbon. 2D NiFe-LDHs inhibited soil sucrase (S-SC) activity, but enhanced soil urease (S-UE) activity. Conversely, NiFeS-LDHs inhibited catalase (S-CAT) activity and S-UE activity, while promoting neutral phosphatase (S-NP) activity However, as concentrations increased, the effects of 2D NiFe-LDHs and 3D NiFeS-LDHs on soil properties and enzyme activities became more similar. Both NiFe-based LDHs altered the diversity of soil bacterial and fungal communities, with 3D NiFeS-LDHs exerting a stronger inhibitory effect on fungal diversity at higher concentrations. The structural differences in NiFe-based LDHs exert a distinct and substantial impact on the composition of soil microbial communities and soil enzyme activities. The findings provide critical insights into bio-effects of NiFe-based LDHs, which provide a theoretical basis for the study of potential ecological risks in soil.