To report the clinical and imaging findings of a patient with right eye progressive vision loss, in whom ocular neurocysticercosis was diagnosed. The patient underwent vitreoretinal surgery with previous antihelmintic treatment, resulting in a successful extraction of the subretinal cyst. A patient with subretinal neurocysticercosis underwent a combination of ophthalmic examination, fundus photography, ocular ultrasound, brain MRI, and surgery. A 57-year-old female from La Guajira, Colombia presented with a 2-year history of unilateral subretinal neurocysticercosis and an overlying exudative inferior retinal detachment with multiple areas of RPE atrophy. Different methods of surgery were contemplated to achieve a favorable outcome, until deciding on a microincision vitrectomy surgery. An "in vivo" minimally invasive pars plana approach should be considered, given it has proven to be successful in removing intraocular cysts with no postoperative inflammatory response, preserving anatomic and functional integrity.
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