Konya Training Research Articles

The Effect of Folic Acid Supplementation in the First Trimester of Pregnancy on Perinatal Outcomes: A Retrospective Cohort Study

Background: The purpose of this study is to compare the perinatal outcomes of pregnant women who received folic acid (FA) supplements to those who did not, using a large sample size. Methods: This study was conducted retrospectively at Konya Training and Research Hospital between 2016 and 2020. The study included pregnant women who took FA and those who did not. We obtained sociodemographic data and perinatal outcomes of all pregnant women from the electronic record system. We learned about folic acid usage from the e-prescription tracking system. Results: Out of the total sample size of 2393 patients, n = 861 (35.97%) received FA supplements during pregnancy, while n = 1532 (64.02%) did not. The gestational age at birth in the group receiving FA was higher than in the group not receiving FA (271.59 ± 13.83 days vs. 270.09 ± 15.27 days, p = 0.005). The group that did not take FA had more neonatal intensive care unit (NICU) admissions than the group that did (5.09% vs. 2.90%, p = 0.011). In the group that took FA, there were n = 17 (1.97%) patients with gestational diabetes (GDM), whereas in the group that did not use FA, there were n = 15 (0.98%) patients with GDM (p < 0.001). Conclusions: The group taking FA supplements had a higher gestational age at birth and GDM, while admission to the NICU were lower compared to the group not taking FA supplements.

Evaluation of the Clinical, Laboratory and Radiology Findings and Treatment Methods of Children with Acute Bronchiolitis: Experience of a Tertiary Center.

The aim of this study is to determine the factors affecting the duration of hospitalization and causing the initiation of antibiotics in children with acute bronchiolitis. This study was conducted retrospectively in Konya Training and Research Hospital. Demographic data, clinical features, laboratory and radiological findings, treatment methods and duration of hospitalization of 102 patients followed up in the pediatric service between September 2017 and April 2019 (in autumn, winter and spring seasons) were recorded from patient files. 67 (65.7%) of 102 patients were male, and 35 (34.3%) were female. Median age was 6.5 (11.0) months. According to Wang bronchiolitis clinical scoring, 36 (35.3%) of the patients were mild, 51 (50.0%) were moderate, 15 (14.7%) were severe bronchiolitis The most common agents in polymerase chain reaction (PCR) were respiratory syncytial virus 60 (58.8%), influenza virus 20 (19.6%), rhinovirus 15 (14.7%), bocavirus 15 (14.7%) and parainfluenza virus 12 (11.7%). The median duration of hospitalization was 7.0 (4.0) days. Forty-two (41.2%) of the patients were hospitalized for ≤5 days, and 60 (58.8%) were hospitalized for >5 days. Duration of hospitalization was significantly and positively correlated with crepitant crackles, leukocytosis, neutrophilia, and coinfection with influenza virus (p=0.036, p=0.034, p=0.028, p=0.036, respectively). Duration of hospitalization was significantly and negatively correlated with pH and increased aeration (p=0.002, p=0.003, respectively) Antibiotic initiation was significantly and positively correlated with wheezing, crepitant crackles, leukocytosis, and neutrophilia (p=0.033, p=0.013, p=0.028, p=0.002, respectively). A significant relationship was found between crepitant crackles in physical examination, respiratory acidosis in laboratory, co-infection with influenza virus detected by PCR and hospitalization for more than 5 days. A significant relationship was determined between wheezing or crepitant crackles in physical examination, leukocytosis or neutrophilia in laboratory and the initiation of antibiotic.

Analysis of Newborn Hearing Screening Test Results of Children with Down Syndrome.

Aim:The aim of this study was to analyze newborn hearing screening test results of children with Down syndrome (DS).Methods:The files of 84 children with DS and 84 healthy children (control group) admitted to the Pediatrics Polyclinics of the Konya Training and Research Hospital between January 2017 and June 2020 were retrospectively reviewed.Results:Thirty-one of the 84 babies with DS were female (36.9%), and 53 were male (63.1%); 37 of the 84 babies in the control group were female (44%), and and 47 were male (56%) (P = .346). Fortty-eight (57.1%) of the 84 babies with DS and 17 (20.2%) of the 84 babies in the control group failed the first screening test (P < .001). It was determined that 24 (50%) of the 48 infants with DS who failed the first test also failed the second test and were referred, and all 17 infants in the control group who failed the first test passed the second test (P < .001). There was no significant difference in terms of birth weight, gestational week, and maternal age between infants with DS who failed and passed after the second screening test (P > .05 for all).Conclusion:Our study shows that birth weight, gestational age, and maternal age do not pose an additional risk for hearing loss in DS babies who do not have known risk factors for hearing loss.

COMPARISON OF LICHTENSTEIN AND DESARDA REPAIRS IN INGUINAL HERNIAS IN TERMS OF POSTOPERATIVE CHRONIC PAIN AND RECURRENS; A PROSPECTIVE RANDOMIZED TRIAL

Objective&#x0D; Patient comfort is an important factor affecting the&#x0D; outcome and success of inguinal hernia repairs.&#x0D; Mesh usage significantly decreases recurrence rate&#x0D; however, the problems due to mesh usage negatively&#x0D; affects the patient comfort. Desarda repair using the&#x0D; body's own tissues has gained importance because&#x0D; it is more physiological and has low recurrence&#x0D; rates. In this study, we aimed to compare Desarda&#x0D; and Lichtenstein repairs in terms of chronic pain and&#x0D; recurrence.&#x0D; Material and Method&#x0D; Patients who were operated on at Konya Training&#x0D; and Research Hospital between October 2010&#x0D; and February 2014 were included in the study.&#x0D; Randomization was done using the closed envelope&#x0D; method. Desarda repair was performed in the first&#x0D; group (D), and Lichtenstein repair was performed in&#x0D; the second group (L). Both techniques were applied&#x0D; as originally described. 3 questionnaires were&#x0D; used in the assessment of chronic pain. All three&#x0D; questionairres were filled before the operation, after&#x0D; first and third year from the operation.&#x0D; Results&#x0D; 162 people participated in the research. There&#x0D; were 80 people in the Desarda group and 82 in the&#x0D; Lichtenstein group. The median follow up time was&#x0D; 122 (96-145) months. There were 2 cases with&#x0D; recurrence in each groups. Preoperative pain levels&#x0D; were similar. The pain incidence, severity and limited&#x0D; activity were similar in the first and third years. The&#x0D; mean operation time was significantly lower in D&#x0D; group than L group (44.5±3.7 min and 56.7±2.97 min&#x0D; respectively). Complication rates were similar in both&#x0D; groups.&#x0D; Conclusion&#x0D; Desarda technique can safely used for hernia repair&#x0D; with its similar recurrance, complications and chronic&#x0D; pain rates with the most commonly used Lichtenstein&#x0D; technique. Moreover, it is advantageous with&#x0D; physiological closure of myopectineal orifice, being&#x0D; easy to perform, not containing foreign material and&#x0D; being cost-effective.

Correlation of [18F]FDG PET activity with expressions of Ki-67 in non-small-cell lung cancer.

Lung carcinoma is the most commonly diagnosed cancer throughout the world and is the leading cause of cancer-related deaths. Non-small cell lung cancer (NSCLC) accounts for up to 80% of newly diagnosed lung cancer cases. This study aimed to investigate the relationship between Ki-67 proliferation index (PI) and the maximum standardized uptake value (SUVmax) obtained from [18F]FDG PET/CT in NSCLCs and whether prognosis was predicted with SUVmax values. This retrospective study included biopsy and resection materials of 41 patients, who were examined in the pathology laboratory of Konya Training and Research Hospital between January 2010 and December 2019, and diagnosed with NSCLC, and whose [18F]FDG PET/CT images were present. There was no significant difference between histopathological subtypes in terms of age (p = 0.077), Ki-67 PI (p = 0.454), and SUVmax (p = 0.143). No correlation was observed between Ki-67 PI and SUVmax values obtained from [18F]FDG PET/CT (p = 0.338, r = 0.153). There was no significant correlation between Ki-67 PI and tumor diameter (p = 0.531). The SUVmax value was found to be lower (12.78 ± 6.14) in tumors measuring ≤ 2.5 in diameter and higher (18.46 ± 7.81) in tumors measuring > 2.5 cm (p = 0.027). Metastases not proven histopathologically but detected in [18F]FDG PET/CT were found to have no significant correlation with Ki-67 and SUVmax values (p = 0.881, p = 0.837). This study showed that there was no significant relationship between Ki-67 PI and SUVmax value obtained from [18F]FDG PET/CT in NSCLC tumors.

An Approach to Blood and Blood Product Transfusion/Reactions

Objective: Transfusion of blood and blood products is life-saving in the right indication; however, it may cause serious complications that may lead to mortality. This study aimed to determine the level of knowledge of allied health personnel about blood and blood product transfusion and to raise awareness about this issue as a result. Materials and Methods: In our study, 191 assistant healthcare professionals serving the adult age group in Konya Training and Research Hospital were surveyed with 24 questions via the website. Results: The rate of correctly knowing all the symptoms related to the transfusion reaction was 31.9%, and 37.6% of the signs. After the grouping of years of service, the rate of correctly knowing transfusion symptoms and signs was similar between the groups, while the rate of knowing the right approach in case of reaction was higher in those with a service year of >20 years. The rate of recognizing the symptoms suggestive of transfusion reaction was higher in those who received transfusion training compared to those who did not receive training (39.1% - 25.3%). Conclusion: It was deduced that the training should be repeated at frequent intervals since it was determined that the rate of correct answers to the survey questions was high among those who have worked in the profession for a longer period and those who have received transfusion training.

Sistemik İsotretinoin Tedavisi Alan Akne Vulgaris Hastalarında Nötrofil- Lenfosit Oranı ve C-Reaktif Protein Düzeyleri

Introduction and Aim: Inflammatory mediators have importance in acne vulgaris pathogenesis. Which mediators cause lesions or increase with which variants is not clear. Neutrophil-lymphocyte ratio and C-reactive protein are the inflammatory indicators that used for follow up of inflammatory diseases. There are various studies state that neutrophil-lymphocyte ratio and C-reactive protein levels are important for systemic isotretinoin treatment or not. Evaluation of changes in neutrophil-lymphocyte ratio and C-reactive protein levels with systemic isotretinoin treatment is the aim of this study. Material and Method: Acne vulgaris patients who are treated with systemic isotretinoin and healthy control subjects between January 2006 and December 2016 in Konya Training and Research Hospital Dermatology outpatient clinic are included to study. Neutrophil-lymphocyte ratio and C-reactive protein levels compared in each group at the beginning of treatment and at the 3rd month. Results: 50 patients (28 of women and 22 of men) who are treated with systemic isotretinoin for acne vulgaris and 50 healthy control patients (21 of women and 29 of men) included to study. Mean age of treatment group was 21 (19-23) and control group was 29,5. Neutrophil-lymphocyte ratio are not found statistically significiant in patients and control group at the begining and middle of the treatment (1,84,[3,36-0,51] – 1,62,[4,07-0,68], p:0,107), C-reactive protein levels show a statistically significiant decrease in patient group with treatment (p&amp;lt;0,028). Conclusion: Systemic isotretinoin treatment may affect neutrophil-lymphocyte ratio and C-reactive protein levels in patients. Further studies are needed to clarify this relation.

The evaluation of the cases with extrapulmonary tuberculosis

Objective: Tuberculosis (TB) that can involve all organs is a disease progressing with a wide range of clinical presentations. It is especially difficult to diagnose the cases of extrapulmonary tuberculosis (EPTB) due to the atypical course, and the cases of EPTB constitute approximately 35% of all TB cases in our country. In our study, it was aimed to examine the distribution rates, diagnostic methods, and treatment processes of EPTB in terms of the involved systems.&#x0D; Material-Method: Of 308 patients diagnosed with TB, 119 cases having EPTB were retrospectively analyzed in The Konya Training and Research Hospital of Health Sciences University between 1st January 2015 and 30th June 2019.&#x0D; Results: While 119 (38.6%) EPTB cases of 308 cases diagnosed with TB were included in the study. 63 (52.9%) and 56 (47%) patients were women and men, respectively. The average age was found as 44.42±18.8 years (min: 18- max: 91 years). The distribution of involvement sites of EPTB was as follows: lymphadenitis, 45.3%; pleural tuberculosis, 24.3%; peritonitis, 14.2%; bone-joint tuberculosis, 7.5%; meningitis, 2.5%; miliary tuberculosis, 1.6%; others, 4.2%. In terms of EPTB, 83 (69.7%) cases were diagnosed histopathologically, 28 (23.5%) and nine (7.5%) were found to have culture and acido-resistant bacilli (ARB) positivity, respectively. A total of 29 (24.3%) cases were diagnosed microbiologically, and the purified protein derivative (PPD) positivity was detected in 106 (89%) cases. While the success rate of the treatment was found to be 93.2%, the mortality rate was measured as 3.3%. &#x0D; Conclusion: It should be kept in mind that TB is a common multisystem disease in our country and may present itself with a wide range of symptoms. In the presence of clinical suspicion, supportive tests should be performed; biopsy and culture samples should be obtained from the appropriate tissues; anti-TB treatment should be initiated at once if clinicians have sufficient evidence.

Awareness of cervical cancer, human papilloma virus (HPV) and HPV vaccination among women in a cancer screening, early diagnosis and education center

Aim: This study was conducted to assess the awareness of women about cervical cancer and human papilloma virus (HPV) and to evaluate their HPV DNA test results.Materials and Methods: This analytical cross-sectional study was conducted in 250 women who applied to Cancer Early Diagnosis Screening and Training Center (KETEM) at Konya Training and Research Hospital of Health Sciences University. A questionnaire prepared by the researchers was applied to determine the women's sociodemographic characteristics, cervical cancer and HPV knowledge levels.Results: The mean age of the women was 47.7 ± 7.5 years old. When the smear results of the women included in the study are examined, HPV was positive in 3.2% (n=8). Participants with higher education levels had significantly higher Pap smear test knowledge and performed more Pap smear tests than those who had lower education levels (p<0.001). Participants with higher monthly income had significantly higher levels of HPV vaccination knowledge (p=0.014). Women who had regular gynecological examinations, had higher screening test knowledge and had Pap smear tests more than those who were not screened regularly (p<0.001). Participants who know what is a Pap smear test, had a significantly higher HPV vaccine knowledge (p<0.001). Women who had higher education levels had a significantly higher knowledge level about HPV-related lesions (p<0.001).Conclusions: Pap smear test rates, awareness and knowledge regarding HPV, cervical cancer and HPV vaccine were appeared to be very low in our study. It is possible to reduce disorders caused by HPV infection and cervical cancer incidence by improving awareness for cervical cancer and HPV infection, generalizing use of preventive measures, and extending participation to screening programs and HPV vaccination.

Acute respiratory distress syndrome (ARDS) after valproic acid toxicity in the intensive care unit: Case report.

Bipolar DisordersVolume 22, Issue 5 p. 541-542 CLINICAL CURIOSITY Acute respiratory distress syndrome (ARDS) after valproic acid toxicity in the intensive care unit: Case report Ayşe İlksen Eğilmez, Corresponding Author Ayşe İlksen Eğilmez ilksenayten@gmail.com Anesthesiology and Reanimation Department, Health and Science University, Konya Training and Research Hospital, Konya, Turkey Correspondence Ayşe İlksen Eğilmez, Anesthesiology and Reanimation Department, Health and Science University, Konya Training and Research Hospital, Konya, Turkey. Email: ilksenayten@gmail.comSearch for more papers by this authorYasin Tire, Yasin Tire orcid.org/0000-0002-9905-8856 Brain and Nerve Surgery Department, Health and Science University, Konya Training and Research Hospital, Konya, TurkeySearch for more papers by this author Ayşe İlksen Eğilmez, Corresponding Author Ayşe İlksen Eğilmez ilksenayten@gmail.com Anesthesiology and Reanimation Department, Health and Science University, Konya Training and Research Hospital, Konya, Turkey Correspondence Ayşe İlksen Eğilmez, Anesthesiology and Reanimation Department, Health and Science University, Konya Training and Research Hospital, Konya, Turkey. Email: ilksenayten@gmail.comSearch for more papers by this authorYasin Tire, Yasin Tire orcid.org/0000-0002-9905-8856 Brain and Nerve Surgery Department, Health and Science University, Konya Training and Research Hospital, Konya, TurkeySearch for more papers by this author First published: 11 June 2020 https://doi.org/10.1111/bdi.12951Citations: 1Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume22, Issue5August 2020Pages 541-542 RelatedInformation

The Effect of Beta-Trace Protein on Diagnosis and Prognosis in Patients with Acute Coronary Syndrome.

ObjectiveThe purpose of this study was to determine the effect of beta-trace protein (BTP) levels at the time of admission and at 8th hour on diagnosis and prognosis in patients who were under treatment and follow-up with acute coronary syndrome (ACS) diagnosis at coronary intensive care unit and emergency department.Materials and MethodsThis study was conducted between June 2014 and December 2014 at the Emergency Department of Konya Training and Research Hospital. Demographic characteristics, background, vital findings, laboratory findings, blood BTP levels, coronary angiography results, and echocardiography findings of the patients diagnosed with ACS were recorded. Risk classification was performed for patients with ACS and their mortality rates were recorded. Relation of BTP level with risk classification and mortality was evaluated.ResultsA total of 174 individuals, 138 patients and 36 control subjects, were included in the study. No significant difference was detected between BTP levels at the time of admission and at 8th hour in the patient group (p=0.883). There was no difference between the patient and control groups in terms of the BTP level (p=0.335). Ten patients (7.2%) died in the patient group. BTP levels measured at the time of admission and at 8th hour were not different for dead and living patients (admission p=0.085, 8th hour p=0.141).ConclusionWe determined that there was a lack of biochemical markers that could be used for the prognosis of serum BTP levels in patients admitting to the emergency unit with ACS.

Pulmonary Hypertension in Children with Lower Respiratory Tract Infections in the Konya Province of Turkey

Abstract Objective Lower respiratory tract infections (LRTI) are one of the most important causes of morbidity and mortality in childhood. Hypoxemia, pulmonary hypertension (PH) due to pulmonary vasoconstriction, and heart failure due to various causes are the most important risk factors for mortality in LRTI. The aim of this study was to investigate characteristics of the patients with LRTI and the frequency of PH that developed secondary to LRTI. Materials and Methods The study included 70 patients who were diagnosed as having LRTI clinically and radiologically between January 2012 and March 2013 at Department of Pediatrics, Konya Training and Research Hospital. Age, sex, risk factors for LRTI, symptoms and physical examination findings, laboratory tests, and Doppler echocardiography findings of the patients were retrospectively reviewed. Results Of the patients, 44 (62.9%) were male and 26 (37.1%) were female. Thirty-seven (52.9%) patients were younger than 1 year, and the mean age was 2.5 ± 3.11 years. The most common symptoms of the patients were cough and fever. Rhonchus, retraction, and crackles were found to be the most common findings in physical examinations. Heart failure was found in 10% of patients and PH was detected in 8.6% through Doppler echocardiography. Development of heart failure and the presence of bilateral patch infiltration on posteroanterior chest X-rays were significantly more frequent in patients with PH. Some 42.9% of patients had at least one viral agent in their nasopharyngeal swabs. The most common viral agents were respiratory syncytial virus and rhinoviruses. Conclusion PH may develop during the course of LRTI in children. Given that the development of PH can cause life-threatening complications such as heart failure, affected patients should be kept under close follow-up. It should be remembered that PH is more likely to develop in patients with bilateral patch infiltration on chest X-ray.

The Comparison of LISA and INSURE techniques in term of neonatal morbidities and mortality among premature infants.

Background and aim of the work:Respiratory distress syndrome (RDS) is the most common cause of respiratory failure among premature infants. The most important choice for the treatment of RDS is still exogenous surfactant replacement therapy and respiratory support. Today, there are some different surfactant applying techniques. In this study, we aimed to evaluate the effects of the surfactant administration techniques in premature infants less than 33 weeks of gestational age.Methods:The medical data were collected retrospectively from the medical records of Baskent University, Konya Training and Research Hospital between 2010 and 2016. The patient divided into two subgroups as Less Invasive Surfactant Administration (LISA) group (n: 35) and Intubation- Surfactant administration and rapid Extubation (INSURE) group (n: 30). Two surfactant administration techniques were evaluated on the neonatal morbidities and mortality among premature infants.Results:There were no significant differences in maternal and neonatal characteristics between the two groups. Duration on the nasal continues positive airway pressure (nCPAP) is significantly higher in the LISA group as compared with the INSURE group (p<0.001). And also between two groups, there were no significant differences in term of neonatal mortality and morbidities.Conclusion:The technique of the surfactant administration has no effect on the postnatal morbidities. LISA method is safe and effective as much as INSURE method, which is still a good alternative in centers with lack of experience about LISA. We need to perform studies that have larger sample size and prospective randomized controlled trials. (www.actabiomedica.it)

Changes in thiol/disulfide homeostasis in patients with chronic kidney disease

Thiol/disulfide homeostasis (TDH) is a new marker of oxidative stress. In this study, we would like to determine the changes in TDH in hemodialysis (HD) patients with chronic kidney disease (CKD). This cross-sectional study was conducted in the Nephrology Clinic of Konya Training and Research Hospital. A total of 197 individuals including 75 HD patients, 41 end stage renal disease (ESRD) patients (having stage 3-5 CKD but not receiving hemodialysis), and 81 healthy controls were enrolled in the study. Serum native thiol, total thiol, and disulfide levels were measured with a new method developed by Erel and Neselioglu. It was determined that there was a statistically significant difference in the mean age, body mass index (BMI), modification of diet in renal disease (MDRD), and creatinine level between the three groups (p

PLASMA ATHEROGENIC INDEX IS AN INDEPENDENT INDICATOR AND PROGNOSTIC VALUE IN RAYNAUD’S PHENOMENON?

Objective: Raynaud’s phenomenon (RP) is characterized by cold induced temporary ischaemia of the fingers or toes and an inflammatory autoimmune disease of connective tissues. Plasma atherogenic index (PAI) is a valuable marker for the cardiovascular disease and cardiac risk. The aim of this study was to evaluate the role and clinical use of PAI in RP patients.&#x0D; Materials and Methods: In this retrospective-cohort study, we examined the clinical value count blood cells in 55 patients with RP and 14 clinical controls admitted Konya Training and Research Hospital Department of Cardiovascular Surgery between January 2016-March 2019 were investigated retrospectively screened. PAI was measured as a logarithmic value of triglyceride to high-density cholesterol ratio. PAI levels &lt;0.11 is accepted as low risk, 0,11-0,21 intermediate risk, and 0.21 &gt;increased risk. PAI was measured as a logarithmic value of triglyceride to high-density cholesterol ratio. The lipid and other biochemical parameters of patient and control groups were examined and measured.&#x0D; Results: The study consisted of 29 females (42.03%) and 40 males (57.97%). There was a significant difference between differences between PAI level groups. There was no significant difference in PAI results between genders (p&gt;0.355).We also found disagreement in biochemical parameters and PAI between controls and patients.&#x0D; Conclusion: When we evaluated PAI in the patients with RP and controls, it was determined that there was no significant difference in either parameter. However, PAI levels have showed that significant elevated between groups so It can be a simple, economic and non invasive marker to identify for future studies.&#x0D; Keywords: Raynaud’s phenomenon, Plasma atherogenic index, Blood lipid components

Placement of double-J stent in patients with malignant ureteral obstruction: antegrade or retrograde approach?

To determine whether antegrade or retrograde methods should be preferred for double-J stent placement in patients with malignant ureteral obstruction (MUO). The medical records of patients treated for MUO in the Urology and Interventional Radiology Clinic, Konya Training and Research Hospital, were reviewed retrospectively. Patients with benign aetiology were excluded from the study. Reports of the procedures, ultrasonography findings, computed tomography (CT), angiography, and pyelography images and the follow-up records of patients with MUO were assessed. A total of 111 patients and 114 ureteral stenting treatments were included in the study; 63 (55.3%) were operated on using the antegrade ureteral stenting (AUS) method, whereas 51 (44.7%) were operated on using the retrograde ureteral stenting (RUS), method, and the characteristics of these groups were evaluated. The presence of hydroureteronephrosis and ureteral tortuosity were determined. Overall success rates were found to be 95.2% using the AUS method and 47.1% using the RUS method. The technical success of the antegrade method was significantly higher in patients with or without tortuosity (respectively: p=0.005, Z shape p=0.001, pigtail shape p=0.035″). The technical success of the antegrade method was significantly higher in patients with hydroureteronephrosis (p=0.001). The AUS technique should be the first choice for double-J stent placement in patients with MUO.

Associations between night eating syndrome and metabolic parameters in pregnant women.

Objective:In this study, we aimed to evaluate the incidence of night eating in pregnancy and the relationship between night eating scores and nutritional status, insulin resistance, and lipid profile in pregnant women.Materials and Methods:In this study, 148 pregnant women who presented to the Gynecology and Obstetrics Clinics at Konya Training and Research Hospital in Konya were divided into two groups according to their night eating scores. These two groups were compared in terms of their nutritional attitudes and metabolic parameters.Results:Comparisons of participants meeting night eating syndrome (NES) scores versus women without NES indicated that patients with NES exhibited fever hunger at breakfast time, more breakfast skipping (p<0.05) than those without NES. Also homeostatic model assessment insulin resistance, insulin, and high-density lipoprotein cholesterol parameters were significantly higher in pregnant women in the NES group (p<0.05). Also, correlations were found between higher night eating questionnaire total scores and higher HbA1c, insulin resistance, insulin, and more breakfast skipping.Conclusion:The results of this study suggest that night eating symptoms during pregnancy may increase and this is able to effect glucose metabolism.

Suicide attempts and related factors in schizophrenia patients.

Objectives:To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts.Methods:A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the Department of Psychiatry, Selcuk University and the Beyhekim Psychiatric Clinic Konya Training and Research Hospital, Konya, Turkey, between January 2014 and January 2018 The data collection forms created by researchers were completed using hospital medical records.Results:It was determined that 40.8% of schizophrenia patients attempted suicide at least once and that 39.6% of schizophrenia patients who attempted suicide had recurrent suicide attempts. Those with suicide attempts had a significantly longer mean duration of untreated psychosis and a higher total number of hospitalizations compared to those without suicide attempts. In addition, the use of depot antipsychotic drugs was significantly lower in those with suicide attempts. There was a statistically significant difference in the presence of traumatic life events between those with and without suicide attempts.Conclusion:Suicidal behavior is an important problem in schizophrenia. Identifying risk factors and high-risk individuals will guide us in the development of preventive interventions.

Management of acute mitochondriopathy and encephalopathy syndrome in pediatric intensive care unite: a new clinical entity.

Acute mitochondriopathy and encephalopathy syndrome (AMES) is described differently by different authors in the literature. As a new clinical entity, we aimed to present the clinical signs and symptoms, diagnosis and treatment algorithm of our patients with AMES. 56 patients aged between 2months and 18years who were followed up in pediatric intensive care units of Konya Training and Research Hospital and Selcuk University Medical Faculty Hospital, between January 2010 and June 2017 were included. Patients' data were obtained retrospectively from the intensive care unit patient files. 34 (60.7%) of the patients were male and 22 (39.3%) were female. The median age of our patients was 10.0months. At the time of admission, 42 (75%) of the patients had fever, 35 (62.5%) vomiting, 27 (48.2%) abnormal behaviour and agitation and 28 (50%) convulsion. The etiological classification of patients with AMES was divided into four groups as infection, metabolic disorder, toxic, and hypoxic-ischemic. 39 (69.6%) patients were found to have infection, 10 (17.9%) patients hypoxia, 7 (12.5%) patients metabolic disorders. AMES occurs rarely, but should be kept in mind in the differential diagnosis of patients with any encephalopathy of unknown origin especially in those with a history of ingestion of drugs, previous viral infection and vomiting. Early recognition and treatment is imperative to reduce morbidity and mortality in children with AMES.

The comparison of patients with schizophrenia in community mental health centers according to living conditions in nursing home or home

Objective: Community mental health centers constitute the core of the community-based mental health service model. Some of the patients enrolled in these centers that provide support to individuals and their families with severe mental disorders are staying in a nursing home. In this study, it was aimed to compare the sociodemog- raphic, clinical and drug treatment characteristics of the patients living in nursing home with the patients living at home. Methods: The study included a total of 135 patients who were diagnosed with schizophrenia according to DSM-5 criteria and who attended to rehabilitation program at community mental health centers of Selcuk University Faculty of Medicine, Konya Training and Research Hospital, Beyhekim Psychiatry Clinic, Konya Numune Hospital and Konya Eregli State Hospital at least one day in a month. The study design was retrospective, the data collection forms were filled using hospital medical records. Results: A total of 135 patients with schizophrenia were included in the study. While 82 (60.7%) of the patients were living at home, 53 (39.3%) were in the nursing home. The rate of male patients in the nursing home, the average age, the number of days they participated in the rehabilitation program, the duration of the illness, and the smoking rate were significantly higher than the patients who were living at home. When all patients using multiple antipsychotics were evaluated, positive correlation was found between the number of drugs and side effect scale score, Positive and Negative Syndrome Scale total score. According to the logistic regression analysis to determine the variables predicting the use of single antipsychotic or multiple antipsychotic drugs, the male gender and the number of hospitalizations were found to increase the rate of combined drug use. Discussion: In order to improve the service provided in community mental health centers, it is necessary to identify the need areas of patients according to living conditions in nursing home or home, to share the good practices in psychosocial interventions and to increase the awareness in drug treatments in order to make new arrangements in line with the recommendations of the treatment guidelines.