IT Fusion Research Articles

Bispecific human IL2-CCR4 immunotoxin targets human cutaneous T-cell lymphoma.

The majority of clinically diagnosed cutaneous T‐cell lymphomas (CTCL) highly express the cell‐surface markers CC chemokine receptor 4 (CCR4) and/or CD25. Recently, we have developed diphtheria toxin‐based recombinant Ontak®‐like human IL2 fusion toxin (IL2 fusion toxin) and anti‐human CCR4 immunotoxin (CCR4 IT). In this study, we first compared the efficacy of the CCR4 IT vs IL2 fusion toxin for targeting human CD25+CCR4+ CTCL. We demonstrated that CCR4 IT was more effective than IL2 fusion toxin. We further constructed an IL2‐CCR4 bispecific IT. The bispecific IT was significantly more effective than either IL2 fusion toxin or CCR4 IT alone. The bispecific IT is a promising novel targeted therapeutic drug candidate for the treatment of refractory and recurrent human CD25+ and/or CCR4+ CTCL.

A Poster Digital Sain Media for Humanity Interaction based Interactive Augmented Reality

Interactive and innovative learning media supported by Augmented Reality (AR) is specifically used in the field of science in helping the development of student learning process at State University of Malang (UM). This media is designed to build the pillar of learning innovation strategy through IT fusion on curriculum and learning. Specifically, the main target in the development of teaching media with interaction through AR mobile media and science posters integrated with virtual communications is to improve the visual capabilities of information. Several stages to be done to realize this service are: 1)build a framework of the system in a comprehensive manner, 2)testing with a number of students as a user response, 3)making showcase and 4)demonstrating application system with multimedia content with science materials with 3D perspective (animation and interactive video). The software engineering method used in this application development is the waterfall model, while the qualitative method approach is needed to measure the effectiveness and efficacy of this AR science product on increasing the level of student understanding after using this media through a questioner. It is expected that with the development of this media will accelerate the formation of learning innovation in life-based learning in UM in the future. In broader impact, this work will be able to make UM as a learning innovation university as the competitive and superior university as well as become a reference in the technology of learning media.

The Virtual Reality Experience and Leisure Experience of Screen Horse Riding Participants: from the ‘Simulation’ point of view by Boudrillard

This study aims to gain depth understanding of the virtual reality experience experienced by screen riding, to analyze in depth and interpret from the perspective of Boudrillard through a subjective and subjective perspective of leisure users. In this study, after learning about the experience of virtual reality symbols built into them through screen riding, the leisure experience of screen riding participants was further identified. The double-checking results are as follows. First, experience in the virtual reality of screen riding can be described as a fusion of virtual reality symbols and experiences. The virtual reality symbols inherent in screen riding are expressed as spatial symbols, behavioral symbols, and contents, and the fusion of experience means a transcendental and a transformative environment. Second, screen riding was a derivative of the study that enabled participants to enter horseback riding more easily and to continue with leisure activities, also to help with posture correction, constipation, diet, and Kegel exercise. thereby enhancing fun and desire for horseback riding. In the study, participants were focusing on subjective feelings arising from the experience of horseback riding, and they stated that the body's sensory stimuli increased the quality of life and felt happy. In this study, the leisure activities are satisfied with the simulacra which can replace reality according to the subjective viewpoint of the leisure experiencer and the reflection of personal circumstances in the virtual reality of screen riding sports which is IT fusion. In the future, It is necessary to study the consumption patterns and the popularity of the emerging virtual reality sports since various virtual reality sports are becoming popular and are being built into the culture of life.

Making a 3D Geography Teaching Aid and Developing an Augmented Reality App through IT Fusion

Making a 3D Geography Teaching Aid and Developing an Augmented Reality App through IT Fusion

IT Fusion Global Education Methods for Fostering GlobalTeachers

To meet the requirements in the global age, the necessity and importance of global education in the field of education is rapidly increasing. However, according to the viewpoint on global education, a general consensus of its definition and model is not clear yet and the substantial outcome falls short of our Received (February 23, 2016), Review Result (March 9, 2016) Accepted (March 16, 2016), Published (April 30, 2016) 63243 Dept. Computer Education, Jeju Nat’l Univ., 102 Jejudaehak-ro, Jeju-si, Jeju-do, Korea email: jykang@jejunu.ac.kr (Corresponding Author) 63243 Dept. Computer Education, Jeju Nat’l Univ., 102 Jejudaehak-ro, Jeju-si, Jeju-do, Korea email: sbkim@jejunu.ac.kr (Corresponding Author) 63243 Major in Geography Education, Jeju Nat’l Univ., 102 Jejudaehak-ro, Jeju-si, Jeju-do, Korea email: sckwon@jejunu.ac.kr * 이 논문은 제주대학교 글로벌교원양성사업 지원으로 작성되었습니다. * 이 논문은 2015년도 정부(교육과학기술부)의 재원으로 한국연구재단의 지원을 받아 수행된 기초연구사업 (No. 2013R1A1A4A01009428) 지원으로 작성되었습니다. IT Fusion Global Education Methods for Fostering Global Teachers Copyright c 2016 HSST 342 expectation due to high cost, low effectiveness, and lack of persistency in the process of global education. Furthermore, there has been little research on global education for fostering global capabilities of pre-teachers. In this research, we compared and analyzed the ongoing global education programs for training global teachers in domestic universities. Also, through a study on IT fusion education system for tackling the difficulties in global education, we examined appropriate IT fusion education methods. In particular, beased on big data analysis techniques, we presented a recommendation system to complete a global curriculum, which can help a dual-degree or exchange student program.

평균풍속 및 유가변동에 따른 최적 마이크로그리드 구성

Abstract - This paper presents the optimal network configuration for electric stations using HOMER software. For the given data such as annual average wind speed and grid costs, this software calculates the NPC(Net Present Cost), operating cost and COE(Cost of Energy). Based on these simulation results, it is possible to find the optimal network configuration for electric stations depending on the grid cost and average wind speed. When the rising grid cost is considered, it is essential to use grid and renewable energy together. Depending on the increase of the grid cost, NPC of the configuration using renewable energy and grid can be gradually getting smaller than NPC of the configuration using only grid.Key Words : Electric stations, HOMER, Net present cost, Cost of energy†Corresponding Author : Dept. of Electrical Engineering,Hankyong National University, IT Fusion Research Institute, Korea.E-mail : kyuho@hknu.ac.kr* Dept. of Electrical Engineering, Hankyong National University, Korea.Received : November 18, 2014; Accepted : December 29, 2014

광센서를 이용한 안개 탐지 시스템 연구

본 연구에서는 항해 도발적인 기후 변화에 따라 광센서를 이용하여 감지하고 경보를 가능하게 할 수 있는 시스템을 개발하였다. 국내에서는 조선 산업과 IT융합기술에 대한 연구가 활발히 이루어지고 있고, 시급히 선박 운한 시 안개 및 폭우에 따른 시정상태를 항해사에게 경보해 줄 수 있는 고 신뢰성 안전장치 개발이 필요하다. 따라서 본 연구에서는 시스템 개발을 위하여 소형, 소전력의 광센서 송수신기와 센싱 데이터 처리장치를 설계 제작을 하였으며, 성능평가는 시뮬레이션 분석을 통하여 이루어졌다. 측정 방법은 실내 외에서 거리별로 분석하였다. 분석 결과 실내에서 최소 32.36[dB], 최대 89.20[dB]의 값을 측정하였고, 실외에서는 32.55~60.66[dB]까지 측정 되었다. 측정 결과 정상적으로 작동함을 알 수 있었으며 향후 광산업과 더불어 조선기술의 발달에 기초자료로 도움이 될 것이라 사료된다. In this paper, we developed a system which can detect and can alarm about the sailing provocative climate by using a photo. The research on domestic shipbuilding industry and in IT fusion technology is under construction, but a reliable safety device which can alarm a sailor about the circumstances of the fog and rain during ship operation as soon as possible due to the constant state in domestic. In this paper, a compact, for system low-power transceiver and data processing equipment for sensing were developed, also a performance evaluation got accomplished with simulation analysis. In results, it is operating normally at least 32.36[dB] and maximum values f 89.20[dB] in the domestic, and 32.55 to 60.66[dB] in the outdoors.

Java 프로그래밍 학습을 위한 로봇 트레이닝키트의 설계 및 구현

The latest programming paradigm has been mostly geared toward object-oriented programming and visual programming based on the object-oriented programming. However, object-oriented programming has a more difficult and complicated concept compared with that of existing structural programming technique; thus it has been very difficult to educate students in the IT-related department. This study designed and implemented a Java robot training kit in which the Java virtual machine is built so that it may enhance the desire and motivation of students for learning the object-oriented programming using the training kit which is possible to attach various input and output devices and to control a robot. The developed Java robot training kit is able to communicate with a computer through the USB interface, and it also enables learners to manufacture a robot for education and to practice applied programming because there is a general purpose input and output port inside the kit, through which diverse input and output devices, DC motor, and servo motor can be operated. Accordingly, facing the IT fusion era, the wall between the academic circles and the major becomes lower and the need for introducing education about creative engineering object-oriented programming language is emerging. At this point, the Java robot training kit developed in this study is expected to make a great commitment in this regard.

IT융합 차세대 농기계 수출전략형 핵심기술 우선순위 선정에 관한 연구

The objective of this study was to develop the export strategic core technologies for IT fusion next generation agricultural machines by the analysis of comprehensive and cooperative systems of industries, universities, and institutes. In order to achieve the objective of this study, an expert panel was formed and operated. The first survey was conducted by the Delphi method. For this the export strategic core technologies were surveyed and analyzed using the questionnaire. Based on the results of the first survey, the second survey was conducted. The questionnaire used for the second survey was designed by results of the first survey. The results of the second survey was analyzed by AHP method. The third survey was conducted based on the second one, and the final results were analyzed and the export strategic core technologies were developed through the expert meeting. The study results showed six export strategic core technologies as the followings : 1) environment-friendly engine technology for high performance 2) high performance/high efficiency power transmission system technology 3) development of measurement system technology for safety of agricultural products 4) field application of sensor networks 5) large size combine development technology for high performance 6) quality evaluation technology for agricultural products.

Development and Verification of Technical Criteria for a U-Bridge

With the recent acceleration in the adoption of IT in industries, converged Construction-IT has been drawing attention as a new market driver in the IT fusion industry. Despite the simultaneous implementation of U-Cities all over Korea in a manner suiting each city's own attributes, Technical Criteria to build an optimized IT-infrastructure have not yet been prepared. To solve this problem, a standard for U-City construction should be prepared. This research, therefore, draw sample contents in order to establish and verify the criteria for U-City construction. The findings are expected to be meaningful, in that they would serve as significant data for establishing the criteria for future U-City construction.

Errata: Passive regulation of volume-flow ratio for microfluidic streams with different hydrophilicity and viscosity

The corresponding author of this paper is: Professor Youn Tae Kim, Department of IT Fusion Technology, Chosun University, 375 Seosk-dong, Dong-gu, Gwangju 501–759, Korea E-mail: petruskim@chosun.ac.kr Fax: +82-62-233-6896

Molecular Simulations and Conformational Studies of Fucoseα1-3)Gal(β1-X)GlcNAc where X=3, 4, or 6 Oligosaccharides

Energy minimization and conformational studies of molecular ions generated by ESI (electrospray ionization) tandem mass spectrometry (MS/MS) can be used for the discrimination of stereoisomeric permethylated and sodium cationized trisaccharides. Sets of fucose-containing trisaccharides having different internal and terminal linkages have been synthesized to analyze the reducing terminal linkage positions using BT and IT fusion approaches. A detailed investigation has been undertaken on the conformational behaviors of four trisaccharide fragments from human milk and blood group determinants of Type 1 and Type 2, namely Fuc(α13)Gal(β1-3)GalNAc and Fuc(α1-3)Gal(β1-X)GlcNAc where X = 3, 4 and 6 using molecular modeling methods. Three dimensional rigid and adiabatic phi-psi-energy maps (Surfer program) describing the energy as a function of rotation around corresponding glycosidic linkages were calculated by SYBYL molecular modeling and MM4 force field programs conjunction with cleavage energies of ESI MS/MS for the side group orientations. This approach predicted conformational behaviors exhibited by isomer saccharides for future applications on biologically active glycoconjugates and to exploit a faster method of synthesizing a series of structural isomeric oligosaccharides.