ABSTRACT Introduction: Overweight and obesity among children may have psychological consequences, with potentially lasting effects on health-related quality of life (HRQOL). The aims of this study were to compare HRQOL across weight status among children and to determine the factors influencing HRQOL among children with overweight and obesity. Methods: This cross-sectional study involved school children aged 9–16 years that were recruited from eight randomly selected primary and secondary schools in Kuala Lumpur. The validated Malay version of Pediatric Quality of Life Inventory (PedsQL) was used to measure HRQOL. Complex sample general linear model was used to determine the significant factors associated with HRQOL among children with overweight and obesity. Results: From 928 students, 41.2% (n = 375) of them had either overweight or obesity. Children with obesity reported lower overall HRQOL, physical functioning, social functioning, and psychosocial health summary, compared to normal weight children. In the final model, children with obesity had significantly lower HRQOL and physical functioning compared to children who were overweight, while those who lived with a single parent reported poorer HRQOL compared to children who lived with both parents. Children with history of being bullied had lower HRQOL and psychosocial health. Whereas those with lower self-esteem reported significantly lower scores in all three domains. Conclusion: Overweight and obesity have negative impacts on HRQOL of children. Among children with overweight and obesity, factors such as degree of obesity, family structure, history of being bullied, and self-esteem were found to be significantly associated with HRQOL. Therefore, assessing and managing HRQOL should be included as a part of the obesity prevention programme.
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