Intrinsic Movement Research Articles

Detecting Intrinsic Movements through Needle Tips Pinned at Zusanli ST-36 Point - a New Method for Characterizing Structures for Acupuncture Treatments

This study aims to investigate the characteristics of the observed intrinsic movements of needle tips pinned at the Zusanli ST-36 acupuncture point. The specificity of acupuncture points is an important principle underlying the acupuncture treatments and is closely related to the characteristics of some structures attributable to their therapeutic effects. The movements of needle tips pinned at the acupuncture and control points in rats were video recorded, and the position data were analyzed by using the power spectrum and the autocorrelation function. The power spectra in the frequency domain showed main peaks due to oscillations transferred from heart and lung movements, and the spectra showed no distinctive differences between the ST-36 and the control points. The autocorrelation function in the time domain, on the other hand, had different times for the first zero point in the envelope of the oscillating signals: 0.26±0.20 minutes for the ST-36 site and 0.80±0.61 minutes for the control site. The time difference was 0.54±0.45 minutes, which was statistically significant with a p-value = 0.002 from the paired t-test. The results of this study imply that the intrinsic movements transferred to the needle tips pinned at the ST-36 site are more disturbed by some internal mechanical factors than those transferred to the needle tips at the control site are and that the modernized method developed in this study may be a new tool for characterizing structures for acupuncture treatments.

Leprous ganglionitis and myelitis.

A 27-year-old Brazilian woman presented with a 7-month history of progressive pain, tingling, numbness, and weakness of the left upper limb, and paroxysmal dysesthesia affecting the left foot. On examination, there were erythematous, anesthetic patches of skin overlying the metacarpophalangeal joints and on the palmar surfaces of the hands (figure e-1 at [Neurology.org/nn][1]). There was congenital, bilateral campylodactyly and new flexion deformity of the fingers of the left hand with an incomplete range of passive extension. The intrinsic muscles of the left hand were wasted, particularly the thenar eminence and the dorsal interossei. Fasciculations were not observed. There was marked tenderness in the antecubital fossa and at the wrist, and the left superficial radial nerve was palpable. There was severe weakness of intrinsic finger movements, wrist flexion, and extension. Left upper limb reflexes were brisk and painful to percuss but tone, power, and reflexes including plantar responses were otherwise normal. Sensation to pinprick was reduced throughout the left hand with loss of temperature, vibration, and proprioceptive sensation distal to the wrist. Acknowledgment: The authors are grateful to the patient for her permission to publish the case report. They also acknowledge the support and expertise of Professor Diana Lockwood (London School of Hygiene and Tropical Health) whose advice regarding treatment and management has been greatly valued. C.M.R. is supported by the Burden Neurological Institute. [1]: /lookup/doi/10.1212/NXI.0000000000000236

Movee: Video Liveness Verification for Mobile Devices Using Built-In Motion Sensors

The ubiquitous and connected nature of camera-equipped mobile devices has greatly increased the value and importance of visual information they capture. Today, broadcasting videos from camera phones uploaded by unknown users is admissible on news networks, and banking customers expect to be able to deposit checks using mobile devices. In this paper, we introduce Movee, a system that addresses the fundamental question of whether the visual stream uploaded by a user has been captured live on a mobile device, and has not been tampered with by an adversary. Movee leverages the mobile device motion sensors and the intrinsic user movements during the shooting of the video. Movee exploits the observation that the movement of the scene recorded on the video stream should be related to the movement of the device simultaneously captured by the accelerometer. Contrary to existing algorithms, Movee has the unique strength of not depending on the audio track. We introduce novel attacks that focus on Movee's defenses, to fabricate acceleration data that mimics the motion observed in targeted videos. We use smartphones and wearable smart glasses to collect both genuine and attack data from 13 users. Our experiments show that Movee is able to efficiently detect human and automatically generated plagiarized videos: Movee's accuracy ranges between 68-93 percent on a smartphone, and between 76-91 percent on a Google Glass device.

Intrinsic Pleckstrin Homology (PH) Domain Motion in Phospholipase C-β Exposes a Gβγ Protein Binding Site

Mammalian phospholipase C-β (PLC-β) isoforms are stimulated by heterotrimeric G protein subunits and members of the Rho GTPase family of small G proteins. Although recent structural studies showed how Gαq and Rac1 bind PLC-β, there is a lack of consensus regarding the Gβγ binding site in PLC-β. Using FRET between cerulean fluorescent protein-labeled Gβγ and the Alexa Fluor 594-labeled PLC-β pleckstrin homology (PH) domain, we demonstrate that the PH domain is the minimal Gβγ binding region in PLC-β3. We show that the isolated PH domain can compete with full-length PLC-β3 for binding Gβγ but not Gαq, Using sequence conservation, structural analyses, and mutagenesis, we identify a hydrophobic face of the PLC-β PH domain as the Gβγ binding interface. This PH domain surface is not solvent-exposed in crystal structures of PLC-β, necessitating conformational rearrangement to allow Gβγ binding. Blocking PH domain motion in PLC-β by cross-linking it to the EF hand domain inhibits stimulation by Gβγ without altering basal activity or Gαq response. The fraction of PLC-β cross-linked is proportional to the fractional loss of Gβγ response. Cross-linked PLC-β does not bind Gβγ in a FRET-based Gβγ-PLC-β binding assay. We propose that unliganded PLC-β exists in equilibrium between a closed conformation observed in crystal structures and an open conformation where the PH domain moves away from the EF hands. Therefore, intrinsic movement of the PH domain in PLC-β modulates Gβγ access to its binding site.

CAP support as a source of capital and labour productivity – analytical considerations

The level of internal generation of financial funds, i.e. savings, is limited by the achieved productivity and profitability of production. As aside not, it appears easier to overcome the income problem as the basis for that generation of savings by means of interventionism and the underlying transfer of funds from other fields of operation through the national and EU budget to the agricultural holdings. This is a supplementation of the internally generated funds. In the paper, the authors will signal the basic relations between the savings (and external subsidies), investments and increase in production capital of an agricultural producer and an increase of its labour productivity as a basis of growth of income. The goal is to demonstrate the following relations in this respect that form an intrinsic circuitous movement with mutual interdependencies. For the proof of legitimacy, an analytical model with empirical illustrations will be used. Keywords: agricultural producers, income, efficiency, transfers, subsidies and support for agriculture

Decentralized 4D Trajectory Generation for UAVs Based on Improved Intrinsic Tau Guidance Strategy

A decentralized four-dimensional (4D) trajectory generation method for unmanned aerial vehicles (UAVs), which uses the improved intrinsic tau gravity (tau-G) guidance strategy, is presented in this paper. Based on general tau theory, the current tau-G strategy can only generate the 4D trajectory with zero initial and final velocities, which is not appropriate for decentralized applications. By adding an initial velocity to the intrinsic movement of tau-G strategy, the improved tau-G strategy can synchronously guide the position and velocity to the desired values at the arrival time. In our decentralized 4D trajectory generation method, the improved tau-G strategy is used to plan the 4D trajectories for UAVs. To deal with environmental uncertainty and communication limitations, the receding horizon optimization driven by both sampling time and conflict events is utilized to renew trajectory parameters continually. The simulation results of challenging time-constrained tasks demonstrate that the proposed method can efficiently provide safer and lower-cost 4D trajectories.

Notes on Annotation

Notes on Annotation is one result of the work of the artist Florian Jenett on the Motion Bank Deborah Hay score project ‘Using the Sky’. The starting point for the project was her written score ‘No Time to Fly’ that the three dancer-choreographers invited to participate in the project—Jeanine Durning, Ros Warby and Juliette Map—based their own unique solo adaptations on. In order to account for the intrinsic movement variation in Deborah Hay's choreography, the decision was made to record as many versions as possible. To create a framework for analysing and comparing these twenty-one performances—seven from each performer—Jenett took on the task of annotating all video recordings. He used an altered version of the Piecemaker software developed by The Forsythe Company member David Kern for annotating their rehearsals. The following Notes on Annotation capture some of what he discovered during that intensive process. The results can be explored on http://scores.motionbank.org/dh

Echocardiography for prognostication during the resuscitation of intensive care unit patients with non-shockable rhythm cardiac arrest

AimTransthoracic echocardiography (TTE) during cardiopulmonary arrest (CPA) has been studied in victims of cardiac arrests. Our objective was to evaluate the feasibility and usefulness of TTE in victims of cardiac arrest with non-shockable rhythms hospitalized in intensive care units (ICUs). MethodsThis prospective and observational cohort study evaluated ICU patients with CPA in asystole or pulseless electrical activity (PEA). Intensivists performed TTE during intervals of up to 10s as established in the treatment protocol. Myocardial contractility was defined as intrinsic movement of the myocardium coordinated with cardiac valve movement. PEA without contractility was classified as electromechanical dissociation (EMD), and with contractility as pseudo-EMD. The images, the rates of return of spontaneous circulation (ROSC) and the survival upon hospital discharge and after 180 days were evaluated. ResultsA total of 49 patients were included. Image quality was considered adequate in all cases and contributed to the diagnosis of CPA in 51.0% of the patients. Of the 49 patients included, 17 (34.7%) were in asystole and 32 (65.3%) in PEA, among which 5 (10.2%) were in EMD and 27 (55.1%) in pseudo-EMD. The rates of ROSC were 70.4% for those in pseudo-EMD, 20.0% for those in EMD, and 23.5% for those in asystole. Survival upon hospital discharge and after 180 days occurred only in patients in pseudo-EMD (22.2% and 14.8%, respectively). ConclusionsTTE conducted during cardiopulmonary resuscitation in ICU patients can be performed without interfering with care protocols and can contribute to the differential diagnosis of CPA and to the identification of a subgroup of patients with better prognosis.

Perception of social interactions for spatially scrambled biological motion.

It is vitally important for humans to detect living creatures in the environment and to analyze their behavior to facilitate action understanding and high-level social inference. The current study employed naturalistic point-light animations to examine the ability of human observers to spontaneously identify and discriminate socially interactive behaviors between two human agents. Specifically, we investigated the importance of global body form, intrinsic joint movements, extrinsic whole-body movements, and critically, the congruency between intrinsic and extrinsic motions. Motion congruency is hypothesized to be particularly important because of the constraint it imposes on naturalistic action due to the inherent causal relationship between limb movements and whole body motion. Using a free response paradigm in Experiment 1, we discovered that many naïve observers (55%) spontaneously attributed animate and/or social traits to spatially-scrambled displays of interpersonal interaction. Total stimulus motion energy was strongly correlated with the likelihood that an observer would attribute animate/social traits, as opposed to physical/mechanical traits, to the scrambled dot stimuli. In Experiment 2, we found that participants could identify interactions between spatially-scrambled displays of human dance as long as congruency was maintained between intrinsic/extrinsic movements. Violating the motion congruency constraint resulted in chance discrimination performance for the spatially-scrambled displays. Finally, Experiment 3 showed that scrambled point-light dancing animations violating this constraint were also rated as significantly less interactive than animations with congruent intrinsic/extrinsic motion. These results demonstrate the importance of intrinsic/extrinsic motion congruency for biological motion analysis, and support a theoretical framework in which early visual filters help to detect animate agents in the environment based on several fundamental constraints. Only after satisfying these basic constraints could stimuli be evaluated for high-level social content. In this way, we posit that perceptual animacy may serve as a gateway to higher-level processes that support action understanding and social inference.

Affective Movement Recognition Based on Generative and Discriminative Stochastic Dynamic Models

For an engaging human-machine interaction, machines need to be equipped with affective communication abilities. Such abilities enable interactive machines to recognize the affective expressions of their users, and respond appropriately through different modalities including movement. This paper focuses on bodily expressions of affect, and presents a new computational model for affective movement recognition, robust to kinematic, interpersonal, and stochastic variations in affective movements. The proposed approach derives a stochastic model of the affective movement dynamics using hidden Markov models (HMMs). The resulting HMMs are then used to derive a Fisher score representation of the movements, which is subsequently used to optimize affective movement recognition using support vector machine classification. In addition, this paper presents an approach to obtain a minimal discriminative representation of the movements using supervised principal component analysis (SPCA) that is based on Hilbert-Schmidt independence criterion in the Fisher score space. The dimensions of the resulting SPCA subspace consist of intrinsic movement features salient to affective movement recognition. These salient features enable a low-dimensional encoding of observed movements during a human-machine interaction, which can be used to recognize and analyze human affect that is displayed through movement. The efficacy of the proposed approach in recognizing affective movements and identifying a minimal discriminative movement representation is demonstrated using two challenging affective movement datasets.

Functional optoacoustic imaging of moving objects using microsecond-delay acquisition of multispectral three-dimensional tomographic data.

The breakthrough capacity of optoacoustics for three-dimensional visualization of dynamic events in real time has been recently showcased. Yet, efficient spectral unmixing for functional imaging of entire volumetric regions is significantly challenged by motion artifacts in concurrent acquisitions at multiple wavelengths. Here, we introduce a method for simultaneous acquisition of multispectral volumetric datasets by introducing a microsecond-level delay between excitation laser pulses at different wavelengths. Robust performance is demonstrated by real-time volumetric visualization of functional blood parametrers in human vasculature with a handheld matrix array optoacoustic probe. This approach can avert image artifacts imposed by velocities greater than 2 m/s, thus, does not only facilitate imaging influenced by respiratory, cardiac or other intrinsic fast movements in living tissues, but can achieve artifact-free imaging in the presence of more significant motion, e.g. abrupt displacements during handheld-mode operation in a clinical environment.

Correlating Charge Movements with Local Conformational Changes of a Na+-Coupled Cotransporter

To gain insight into the steady-state and dynamic characteristics of structural rearrangements of an electrogenic secondary-active cotransporter during its transport cycle, two measures of conformational change (pre-steady-state current relaxations and intensity of fluorescence emitted from reporter fluorophores) were investigated as a function of membrane potential and external substrate. Cysteines were substituted at three believed-new sites in the type IIb Na+-coupled inorganic phosphate cotransporter (SLC34A2 flounder isoform) that were predicted to be involved in conformational changes. Labeling at one site resulted in substantial suppression of transport activity, whereas for the other sites, function remained comparable to the wild-type. For these mutants, the properties of the pre-steady-state charge relaxations were similar for each, whereas fluorescence intensity changes differed significantly. Fluorescence changes could be accounted for by simulations using a five-state model with a unique set of apparent fluorescence intensities assigned to each state according to the site of labeling. Fluorescence reported from one site was associated with inward and outward conformations, whereas for the other sites, including four previously indentified sites, emissions were associated principally with one or the other orientation of the transporter. The same membrane potential change induced complementary changes in fluorescence at some sites, which suggested that the microenvironments of the respective fluorophores experience concomitant changes in polarity. In response to step changes in voltage, the pre-steady-state current relaxation and the time course of change in fluorescence intensity were described by single exponentials. For one mutant the time constants matched well with and without external Na+, providing direct evidence that this label reports conformational changes accompanying intrinsic charge movement and cation interactions.

New visuomotor maps are immediately available to the opposite limb

Humans can learn to make accurate movements when the required map between vision and motor commands changes, but can visuomotor maps obtained through experience with one limb benefit the other? Complete transfer would require new maps to be both fully compatible and accessible between limbs. However, when this question is addressed by providing subjects with rotated visual feedback during reaching, transfer is rarely apparent in the first few trials with the unpracticed limb and is sometimes absent altogether. Partial transfer might be explained by limited accessibility to remapped brain circuits, since critical visuomotor transformations mediating unilateral movements appear to be lateralized. Alternatively, if adaptation involves movement representations associated with both extrinsic (i.e., direction of motion in space) and intrinsic (i.e., joint or muscle based) frames of reference, new visuomotor maps might be incompatible with opposite limb use when visual distortions have opposite effects for the two limbs in intrinsic coordinates. Here we addressed this issue when subjects performed an isometric aiming task with the index finger. We manipulated the alignment of visuomotor distortion for the two hands in different reference frames by altering body posture relative to the orientation of the finger and the visual display. There was strong, immediate transfer of adaptation between limbs only when visuomotor distortion had identical effects in eye- and joint-based coordinates bilaterally. This implies that new visuomotor maps are encoded in neural circuits associated with both intrinsic and extrinsic movement representations and are available to both limbs.

Targeted Transtracheal Stimulation for Vocal Fold Closure

Paralysis of the structures in the head and neck due to stroke or other neurological disorder often causes dysphagia (difficulty in swallowing). Patients with dysphagia have a significantly higher incidence of aspiration pneumonia and death. The recurrent laryngeal nerve (RLN), which innervates the intrinsic laryngeal muscles that control the vocal folds, travels superiorly in parallel to the trachea in the tracheoesophageal groove. This study tests the hypothesis that functional electrical stimulation (FES) applied via transtracheal electrodes can produce controlled vocal fold adduction. Bipolar electrodes were placed at 15° intervals around the interior mucosal surface of the canine trachea, and current was applied to the tissue while electromyography (EMG) from the intrinsic laryngeal muscles and vocal fold movement visualization via laryngoscopy were recorded. The lowest EMG thresholds were found at an average location of 100° to the left of the ventral midsagittal line and 128° to the right. A rotatable pair of bipolar electrodes spaced 230° apart were able to stimulate bilaterally both RLNs in every subject. Laryngoscopy showed complete glottal closure with transtracheal stimulation in six of the eight subjects, and this closure was maintained under simultaneous FES-induced laryngeal elevation. Transtracheal stimulation is an effective tool for minimally invasive application of FES to induce vocal fold adduction, providing an alternative mechanism to study airway protection.

A speed invariant human identification system using gait biometrics

Can gait biometrics be used for identification of a person? We feel that each individual has an intrinsic gait behaviour, irrespective of the individual's gait speed. The challenge is to extract this gait behaviour from the gait biometrics. In this paper, we used a computer vision-based technique for gait identification. The silhouette treadmill gait database obtained from OU-ISIR, Japan has been used in this gait research work. We have used 22 subjects walking at different speeds varying from 2 km/hr to 6 km/hr with speed variation of 1 km/hr. The gait energy image GEI has been computed from this gait data. The width of GEI, along the horizontal axis, has been used as the feature vector for training and testing. These features show speed invariance but is intrinsic and unique to the subject. The feature captures the intrinsic hand movement, head node and leg oscillations of the subjects. A probabilistic model based on Bayes' conditional probability rule and connectionist model based on multilayer perceptron neural network have been used for classification. This technique provides a promising result of identifying a subject invariant of the gait speed.

Correlating Charge Movements with Local Conformational Changes of a Na-Coupled Cotransporter

To gain insight into the steady-state and dynamic characteristics of structural rearrangements of an electrogenic secondary-active cotransporter during its transport cycle, two measures of conformational change (presteady-state current relaxations and intensity of fluorescence emitted from reporter fluorophores) were investigated as a function of membrane potential and external substrate. Cysteines were substituted at externally accessible sites in the Na+-coupled inorganic cotransporter (SLC34A2) and the mutants expressed in Xenopus oocytes. Fluorophore labeling at one site resulted in complete suppression of transport activity, whereas Cys-substitution and labeling at 6 other sites had marginal effect on kinetics. For these 6 mutants, the properties of the presteady-state charge relaxations (mid-point potential, apparent valence) were similar, whereas fluorescence intensity changes (delta-F) differed significantly depending on the labeling site. By using a 5-state kinetic model, we simulated the measured delta-F and determined the contributions from each state as a function of membrane voltage to obtain a unique set of apparent quantum yields for each mutant. At one site, delta-F originated from the fluorophore sensing inward and outward conformations, whereas for the other sites delta-F was associated principally with one or the other orientation. In response to step changes in voltage, the presteady-state current relaxation and the time course of change in fluorescence intensity were described by single exponentials. For one mutant, the time constants matched well with and without external Na+, providing direct evidence that the fluorophore at this site reported conformational changes accompanying intrinsic charge movement and cation interactions in response to voltage steps. For other mutants, correlations were found only in the presence of Na+ and V>0. Additional evidence for the movement of parts of the protein into a more aqueous environment was obtained using iodide as a collisional quencher.

Low-Cost Eye Gaze Prediction System for Interactive Networked Video Streaming

Eye gaze is now used as a content adaptation trigger in interactive media applications, such as customized advertisement in video, and bit allocation in streaming video based on region-of-interest (ROI). The reaction time of a gaze-based networked system, however, is lower-bounded by the network round trip time (RTT). Furthermore, only low-sampling-rate gaze data is available when commonly available webcam is employed for gaze tracking. To realize responsive adaptation of media content even under non-negligible RTT and using common low-cost webcams, we propose a Hidden Markov Model (HMM) based gaze-prediction system that utilizes the visual saliency of the content being viewed. Specifically, our HMM has two states corresponding to two of human's intrinsic gaze behavioral movements, and its model parameters are derived offline via analysis of each video's visual saliency maps. Due to the strong prior of likely gaze locations offered by saliency information, accurate runtime gaze prediction is possible even under large RTT and using common webcam. We demonstrate the applicability of our low-cost gaze prediction system by focusing on ROI-based bit allocation for networked video streaming. To reduce transmission rate of a video stream without degrading viewer's perceived visual quality, we allocate more bits to encode the viewer's current spatial ROI, while devoting fewer bits in other spatial regions. The challenge lies in overcoming the delay between the time a viewer's ROI is detected by gaze tracking, to the time the effected video is encoded, delivered and displayed at the viewer's terminal. To this end, we use our proposed low-cost gaze prediction system to predict future eye gaze locations, so that optimized bit allocation can be performed for future frames. Through extensive subjective testing, we show that bit-rate can be reduced by up to 29% without noticeable visual quality degradation when RTT is as high as 200 ms.

Structure, Agency And Hezbollah: a Morphogenetic View

ABSTRACT The role and nature of Hezbollah’s involvement in Lebanese politics has been an omnipresent topic in Middle Eastern studies. The recent ‘Arab Spring’ uprisings further accentuated this complex role, given the party’s support for every single popular resistance movement in the Arab world, with the exception of Syria, its major political ally in the region. This stark contradiction highlights once again the question of how far Hezbollah should be perceived as a proxy client of both Iran and Syria or whether it represents an intrinsic and genuine local resistance movement. In this article I argue that scholarly treatment of Hezbollah’s nature, which has oscillated between structure-led, agency-led and dualistic types of analyses, is problematic. The article proposes a historically situated dialectical analysis of structure–agency which can potentially explain better how a legitimate social force can still be understood within the premises of proxy client politics.

Selection pressures give composite correlated random walks Lévy walk characteristics

Composite correlated random walks have been posited as a strong alternative to Lévy walks as models of multi-scale forager movement patterns. Here it is shown that if plastic then intrinsic composite correlated random walks will, under selection pressures, evolve to resemble optimal Lévy walks when foraging is non-destructive. The fittest composite correlated random walkers are found to be those that come closest to being optimal Lévy walkers. This may explain why such a diverse range of foragers have movement patterns that can be approximated by optimal Lévy walks and shows that the ‘Lévy-flight foraging’ hypothesis has a broad hinterland. The new findings are consistent with recent observations of mussels Mytilus edulis and the Australian desert ant Melophorus bagoti which suggest that animals approximate a Lévy walk by adopting an intrinsic composite movement strategy with different modes.

The contribution of different cues of facial movement to the emotional facial expression adaptation aftereffect

Probing emotional facial expression recognition with the adaptation paradigm is one way to investigate the processes underlying emotional face recognition. Previous research suggests that these processes are tuned to dynamic facial information (facial movement). Here we examined the tuning of processes involved in the recognition of emotional facial expressions to different sources of facial movement information. Specifically we investigated the effect of the availability of rigid head movement and intrinsic facial movements (e.g., movement of facial features) on the size of the emotional facial expression adaptation effect. Using a three-dimensional (3D) morphable model that allowed the manipulation of the availability of each of the two factors (intrinsic facial movement, head movement) individually, we examined emotional facial expression adaptation with happy and disgusted faces. Our results show that intrinsic facial movement is necessary for the emergence of an emotional facial expression adaptation effect with dynamic adaptors. The presence of rigid head motion modulates the emotional facial expression adaptation effect only in the presence of intrinsic facial motion. In a second experiment we show these adaptation effects are difficult to explain by merely the perceived intensity and clarity (uniqueness) of the adaptor expressions. Together these results suggest that processes encoding facial expressions are differently tuned to different sources of facial movements.